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H. Tovey · SciRah

Researcher profile · Semantic Scholar

H. Tovey

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H. Tovey — researcher profile on SciRah

h-index: 16
Works: 71
Citations: 2,196

Most-cited papers

A randomised phase III trial of carboplatin compared with docetaxel in BRCA1/2 mutated and pre-specified triple negative breast cancer “BRCAness” subgroups: the TNT Trial
A. Tutt, H. Tovey, M. Cheang, S. Kernaghan +34 more
2018Nature Medicine819 citations Open access
Semantic Scholar
Assessment of Molecular Relapse Detection in Early-Stage Breast Cancer.
I. Garcia-Murillas, N. Chopra, I. Comino-Méndez, M. Beaney +18 more
2019JAMA Oncology377 citations Open access
Semantic Scholar
Homologous recombination DNA repair deficiency and PARP inhibition activity in primary triple negative breast cancer
N. Chopra, H. Tovey, A. Pearson, R. Cutts +18 more
2020Nature Communications218 citations Open access
Semantic Scholar
Abstract S3-01: The TNT trial: A randomized phase III trial of carboplatin (C) compared with docetaxel (D) for patients with metastatic or recurrent locally advanced triple negative orBRCA1/2breast cancer (CRUK/07/012)
A. Tutt, P. Ellis, L. Kilburn, Cheryl Gilett +30 more
2015171 citations
Semantic Scholar
Targeting myeloid chemotaxis to reverse prostate cancer therapy resistance
Christina Guo, A. Sharp, B. Gurel, M. Crespo +45 more
2023Nature127 citations Open access
Semantic Scholar
A phase I dose-escalation study of enzalutamide in combination with the AKT inhibitor AZD5363 (capivasertib) in patients with metastatic castration-resistant prostate cancer
M. Kolinsky, P. Rescigno, D. Bianchini, Z. Zafeiriou +26 more
2020Annals of Oncology68 citations Open access
Semantic Scholar
Effect of Celecoxib vs Placebo as Adjuvant Therapy on Disease-Free Survival Among Patients With Breast Cancer: The REACT Randomized Clinical Trial.
R. Coombes, H. Tovey, L. Kilburn, J. Mansi +21 more
2021JAMA Oncology48 citations Open access
Semantic Scholar
Vistusertib (dual m-TORC1/2 inhibitor) in combination with paclitaxel in patients with high-grade serous ovarian and squamous non-small-cell lung cancer
B. Basu, M. G. Krebs, R. Sundar, R. H. Wilson +24 more
2018Annals of Oncology36 citations Open access
Semantic Scholar
Results from the biomarker-driven basket trial of RO5126766 (CH5127566), a potent RAF/MEK inhibitor, in RAS- or RAF-mutated malignancies including multiple myeloma.
M. Chénard-Poirier, M. Kaiser, K. Boyd, P. Sriskandarajah +15 more
201733 citations
Semantic Scholar
Molecular profiling of aromatase inhibitor sensitive and resistant ER+HER2- postmenopausal breast cancers
E. Schuster, E. López-Knowles, Anastasia Alataki, L. Zabaglo +11 more
2023Nature Communications24 citations Open access
Semantic Scholar
Assessment of structural chromosomal instability phenotypes as biomarkers of carboplatin response in triple negative breast cancer: the TNT trial
O. Sipos, H. Tovey, J. Quist, S. Haider +14 more
2020Annals of Oncology23 citations Open access
Semantic Scholar
Proton beam therapy for oropharyngeal cancer (TORPEdO): a phase 3, randomised controlled trial.
David J. Thomson, James M. Price, Matthew Tyler, Matthew Beasley +22 more
2026The Lancet21 citations Open access
Semantic Scholar
A simple digital image analysis system for automated Ki67 assessment in primary breast cancer
Anastasia Alataki, L. Zabaglo, H. Tovey, A. Dodson +1 more
2021Histopathology20 citations Open access
Semantic Scholar
VinCaP: A phase II trial of vinflunine chemotherapy in locally-advanced and metastatic carcinoma of the penis (CRUK/12/021).
L. Pickering, H. Tovey, T. Elliott, S. Burnett +11 more
201819 citations
Semantic Scholar
Clinico-pathologic relationships with Ki67 and its change with short-term aromatase inhibitor treatment in primary ER + breast cancer: further results from the POETIC trial (CRUK/07/015)
J. Bliss, H. Tovey, Abigail Evans, C. Holcombe +14 more
2023Breast Cancer Research17 citations Open access
Semantic Scholar
HER2-enriched subtype and novel molecular subgroups drive aromatase inhibitor resistance and an increased risk of relapse in early ER+/HER2+ breast cancer
M. Bergamino, E. López-Knowles, G. Morani, H. Tovey +12 more
2022EBioMedicine17 citations Open access
Semantic Scholar
Abstract S6-01:BRCA1methylation status, silencing and treatment effect in the TNT trial: A randomized phase III trial of carboplatin compared with docetaxel for patients with metastatic or recurrent locally advanced triple negative or BRCA1/2 breast cancer (CRUK/07/012)
A. Tutt, M. Cheang, L. Kilburn, H. Tovey +30 more
201713 citations
Semantic Scholar
Fracture Risk in Men with Metastatic Prostate Cancer Treated With Radium-223
A. Hijab, S. Curcean, N. Tunariu, H. Tovey +12 more
2021Clinical Genitourinary Cancer12 citations Open access
Semantic Scholar
VinCaP: a phase II trial of vinflunine in locally advanced and metastatic squamous carcinoma of the penis
S. Nicholson, H. Tovey, T. Elliott, S. Burnett +13 more
2021British Journal of Cancer11 citations Open access
Semantic Scholar
Abstract GS3-03: A phase III multicentre double blind randomised trial of celecoxib versus placebo in primary breast cancer patients (REACT – Randomised EuropeAn celecoxib trial)
R. Coombes, H. Tovey, L. Kilburn, J. Mansi +20 more
201811 citations
Semantic Scholar
Randomised single centre double-blind placebo controlled phase II trial of Tocovid SupraBio in combination with pentoxifylline in patients suffering long-term gastrointestinal adverse effects of radiotherapy for pelvic cancer: the PPALM study.
H. Andreyev, J. Matthews, Carolyn Adams, L. Gothard +11 more
2022Radiotherapy and Oncology10 citations Open access
Semantic Scholar
Impact of duration of neoadjuvant aromatase inhibitors on molecular expression profiles in estrogen receptor positive breast cancers
M. Bergamino, G. Morani, J. Parker, Eugene F Schuster +8 more
2021Clinical Cancer Research9 citations Open access
Semantic Scholar
Identifying Biomarkers to Pair with Targeting Treatments within Triple Negative Breast Cancer for Improved Patient Stratification
H. Tovey, M. Cheang
2019Cancers8 citations Open access
Semantic Scholar
The value of baseline 18F-sodium fluoride and 18F-choline PET activity for identifying responders to radium-223 treatment in castration-resistant prostate cancer bone metastases
R. Donners, N. Tunariu, H. Tovey, E. Hall +6 more
2023European Radiology7 citations Open access
Semantic Scholar
Radium-223 in metastatic castration-resistant prostate cancer: whole-body diffusion-weighted magnetic resonance imaging scanning to assess response
Chris Parker, N. Tunariu, H. Tovey, R. Alonzi +16 more
2023JNCI Cancer Spectrum7 citations Open access
Semantic Scholar
Multi-candidate immunohistochemical markers to assess radiation response and prognosis in prostate cancer: results from the CHHiP trial of radiotherapy fractionation
A. Wilkins, B. Gusterson, H. Tovey, C. Griffin +6 more
2023EBioMedicine7 citations Open access
Semantic Scholar
Relationship between ER expression by IHC or mRNA with Ki67 response to aromatase inhibition: a POETIC study
E. López-Knowles, S. Detre, M. Hills, Eugene F Schuster +10 more
2022Breast Cancer Research7 citations Open access
Semantic Scholar
Abiraterone in patients with recurrent epithelial ovarian cancer: principal results of the phase II Cancer of the Ovary Abiraterone (CORAL) trial (CRUK – A16037)
Susana Banerjee, H. Tovey, R. Bowen, E. Folkerd +13 more
2020Therapeutic Advances in Medical Oncology6 citations Open access
Semantic Scholar
Updated efficacy and safety results from the phase I study of intermittent dosing of the dual MEK/RAF inhibitor, RO5126766 in patients (pts) with RAS/RAF mutated advanced solid tumours.
S. Harris, M. D. De Miguel Luken, D. R. Perez, R. P. Lopez +12 more
20166 citations
Semantic Scholar
Short-duration preoperative endocrine therapy alters molecular profiles to predict favourable outcome in ER+/HER2+ early breast cancer: a POETIC translational study
M. B. Sirvén, E. López-Knowles, Xixuan Zhu, H. Tovey +10 more
2025EBioMedicine5 citations Open access
Semantic Scholar
1O Detection of homologous recombination repair deficiency (HRD) in treatment-naive early triple-negative breast cancer (TNBC) by RAD51 foci and comparison with DNA-based tests
V. Elizalde, A. Llop-Guevara, A. Pearson, C. Cruz +16 more
20215 citations Open access
Semantic Scholar
A phase I dose-escalation study of enzalutamide in combination with the AKT inhibitor AZD5363 in patients with mCRPC.
M. Kolinsky, P. Rescigno, D. Bianchini, Z. Zafeiriou +16 more
20175 citations
Semantic Scholar
PERSEUS1: An Open-label, Investigator-initiated, Single arm, Phase 2 Trial Testing the Efficacy of Pembrolizumab in Patients with Metastatic Castration-resistant Prostate Cancer with Mismatch Repair Deficiency and Other Immune-sensitive Molecular Subtypes.
P. Rescigno, M. D. Fenor de la Maza, H. Tovey, G. Villacampa +39 more
2025European Urology Oncology4 citations Open access
Semantic Scholar
Integrated Multimodal Analyses of DNA Damage Response and Immune Markers as Predictors of Response in Metastatic Triple-Negative Breast Cancer in the TNT Trial (NCT00532727)
H. Tovey, O. Sipos, J. Parker, K. Hoadley +15 more
2023Clinical Cancer Research4 citations Open access
Semantic Scholar
P3.02c-003 TAX-TORC: The novel combination of weekly paclitaxel and the dual mTORC1/2 inhibitor AZD2014 for the treatment of squamous NSCLC.
M. Krebs, J. Spicer, Nicola Steele, D. Talbot +12 more
20174 citations Open access
Semantic Scholar
Managing non-proportionality of hazards (PH) within TNT: a randomised phase III trial of carboplatin compared to docetaxel for patients with metastatic or recurrent locally advanced triple negative (TN) or brca1/2 breast cancer (BC)
H. Tovey, J. Bliss, A. Tutt, J. Morden +5 more
2015Trials4 citations Open access
Semantic Scholar
Concordance of intrinsic subtyping and risk of recurrence (ROR) scores between matched primary and metastatic tissue from Triple Negative Breast Cancer Trial (TNT).
M. Cheang, J. Bliss, M. Dowsett, L. Kilburn +11 more
20153 citations
Semantic Scholar
Abstract OT2-05-01: The HER2-RADiCAL study (Response ADaptive CAre pLan) - Tailoring treatment for HER2 positive early breast cancer
I. Macpherson, S. McIntosh, L. Kilburn, H. Tovey +17 more
2022Cancer Research2 citations
Semantic Scholar
Fracture risk after radium-223 (Ra-223) in metastatic castration resistant prostate cancer (mCRPC).
R. Alonzi, C. Parker, N. Tunariu, D. Koh +10 more
2019Journal of Clinical Oncology2 citations
Semantic Scholar
A phase I trial of selective PI3K inhibitor taselisib (tas) plus palbociclib (palb) with and without endocrine therapy incorporating pharmacodynamic (PD) studies in patients (pts) with advanced cancers.
J. Lim, U. Asghar, N. Diamantis, S. Ward +15 more
20172 citations
Semantic Scholar
Principal results of the cancer of the ovary abiraterone trial (CORAL): A phase II study of abiraterone in patients with recurrent epithelial ovarian cancer (CRUKE/12/052)
Susana Banerjee, L. Kilburn, R. Bowen, H. Tovey +16 more
20162 citations Open access
Semantic Scholar
Abstract PD15-02: HER2-enriched subtype and novel molecular subgroups drive aromatase inhibitor resistance and an increased risk of relapse in early ER+/HER2+ breast cancer
M. Bergamino Sirvén, E. López-Knowles, G. Morani, H. Tovey +9 more
2022Cancer Research1 citations
Semantic Scholar
VinCaP: a phase II trial of vinflunine in locally advanced and metastatic squamous carcinoma of the penis
S. Nicholson, H. Tovey, T. Elliott, S. Burnett +13 more
2021British Journal of Cancer1 citations Open access
Semantic Scholar
Abstract P1-06-07: Characterization of chromosomal instability in the TNT trial: A randomized phase III trial of carboplatin compared with docetaxel for patients with metastatic or recurrent locally advanced triple negative or BRCA1/2 breast cancer (CRUK/07/012)
O. Sipos, H. Tovey, J. Quist, S. Haider +12 more
2019Poster Session Abstracts1 citations
Semantic Scholar
Does 18F-sodium fluoride PET/CT have a role in the assessment of response to 223Ra therapy in men with prostatic bone metastases?
Glen M. Blake, R. Donners, Amelia E. B. Moore, H. Tovey +10 more
2026European Journal of Nuclear Medicine and Molecular Imaging0 citations Open access
Semantic Scholar
A Digital Environment for Multi-modal Relational Management, Representation, and Analysis of Cancer Clinical Studies
F. Rodriguez, X. Zhu, E. Schuster, L. Kilburn +7 more
2026medRxiv0 citations Open access
Semantic Scholar
Abstract A045: The 5G (Next Generation AGile Genomically Guided Glioma) Platform Trial – A First-in-world Adaptive Clinical Trial for Precision Treatment of Brain Tumours
J. Lopez, Diogo J. Silva, Maria L. Thompson, Liam Welsh +23 more
2026Cancer Research0 citations
Semantic Scholar
A Randomized, Phase II Clinical Trial of FLT-PET and FDG-PET for Early Response Assessment of Neoadjuvant Systemic Therapy in Triple-Negative Breast Cancer
Melek Akay, Jennifer Glendenning, H. Tovey, Yi-Ting Tsai +18 more
2026Clinical Cancer Research0 citations Open access
Semantic Scholar
External validation of a digital pathology-based multimodal artificial intelligence (MMAI)-derived prognostic biomarker in the randomised phase III CHHiP trial.
Sarah Stewart, E. Limb, H. Tovey, Yi Ren +16 more
2026Journal of Clinical Oncology0 citations
Semantic Scholar
Invest where impact begins: recommendations from Breast Cancer Research Foundation Early Career Investigator Working Group (Part 1 of 2)
Y. Abdou, M. Rozenblit, Dario Trapani, I. Zerdes +34 more
2026npj Breast Cancer0 citations Open access
Semantic Scholar

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