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H. Than · SciRah

Researcher profile · Semantic Scholar

H. Than

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H. Than — researcher profile on SciRah

h-index: 12
Works: 76
Citations: 1,269

Most-cited papers

A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer
K. Ng, A. Hillmer, C. Chuah, Wen Chun Juan +51 more
2012Nature Medicine594 citations
Semantic Scholar
Combining the Allosteric Inhibitor Asciminib with Ponatinib Suppresses Emergence of and Restores Efficacy Against Highly Resistant BCR-ABL1 Mutants
C. Eide, M. Zabriskie, Samantha L. Savage Stevens, Orlando Antelope +20 more
2019Cancer Cell211 citations Open access
Semantic Scholar
SIRT5 IS A DRUGGABLE METABOLIC VULNERABILITY IN ACUTE MYELOID LEUKEMIA
D. Yan, Anca Franzini, A. Pomicter, Brayden J Halverson +27 more
2019Blood Cancer Discovery58 citations Open access
Semantic Scholar
Pyrvinium selectively targets blast phase-chronic myeloid leukemia through inhibition of mitochondrial respiration
Wei Xiang, J. K. Cheong, Hui-Ang Shi, Bryan Teo +7 more
2015OncoTarget50 citations Open access
Semantic Scholar
The transcriptome of CMML monocytes is highly inflammatory and reflects leukemia-specific and age-related alterations.
Anca Franzini, A. Pomicter, D. Yan, J. Khorashad +5 more
2019Blood Advances44 citations Open access
Semantic Scholar
First experiences with the use of rivaroxaban in the treatment of heparin-induced thrombocytopenia.
H. Ng, H. Than, E.-C.-Y. Teo
2015Thrombosis Research44 citations
Semantic Scholar
A Single-cell Atlas Identifies Pretreatment Features of Primary Imatinib Resistance in Chronic Myeloid Leukemia.
V. Krishnan, Florian Schmidt, Zahid Nawaz, P. Venkatesh +18 more
2022Blood43 citations Open access
Semantic Scholar
NUCLEAR-CYTOPLASMIC TRANSPORT IS A THERAPEUTIC TARGET IN MYELOFIBROSIS
D. Yan, A. Pomicter, S. Tantravahi, C. C. Mason +22 more
2018Clinical Cancer Research38 citations Open access
Semantic Scholar
SRSF1 mediates cytokine-induced impaired imatinib sensitivity in chronic myeloid leukemia
J. R. Sinnakannu, K. Lee, Shanshan Cheng, Jia Li +13 more
2020Leukemia24 citations Open access
Semantic Scholar
Lysosome Inhibition by Mefloquine Preferentially Enhances the Cytotoxic Effects of Tyrosine Kinase Inhibitors in Blast Phase Chronic Myeloid Leukemia
Hui-Lam Yi, H. Than, Colin Sng, M. Cheong +2 more
2019Translational Oncology22 citations Open access
Semantic Scholar
Rivaroxaban for heparin-induced thrombocytopenia: adding to the evidence
Yeu-Ong Shin, Y. Chin, H. Than, Chuen W. Tan +3 more
2017Annals of Hematology16 citations
Semantic Scholar
Favorable outcomes of COVID‐19 in vaccinated hematopoietic stem cell transplant recipients: A single‐center experience
Jing Y. Tan, En-Wee Liang, Y. Tan, E. P. Conceicao +13 more
2023Transplant Infectious Disease12 citations
Semantic Scholar
Conjunctival T Cell Profile in Allogeneic Hematopoietic Stem Cell Transplant Patients after Instilling Topical Cyclosporine-A 0.1% Cationic Emulsion
L. Tong, E. L. Lim, Sharon Yeo, Ai-Hua Hou +7 more
2023Ophthalmology and Therapy10 citations Open access
Semantic Scholar
A comprehensive study of current haemophilia care and outcomes in Singapore
H. J. Ng, J. Lam, P. Koh, Lee-Sang Ho +8 more
2015Haemophilia10 citations
Semantic Scholar
BIM deletion polymorphism profiling complements prognostic values of risk scores in imatinib-treated Asian chronic myeloid leukemia patients
H. Than, W. Lye, Colin Sng, J. C. Allen +2 more
2018Leukemia and Lymphoma8 citations
Semantic Scholar
The EUTOS Score Is Highly Predictive for Clinical Outcome and Survival in Asian Patients with Early Chronic Phase Chronic Myeloid Leukemia Treated with Imatinib
H. Than, Ling-Yee Kuan, C. H. Seow, Wenyun Li +2 more
20128 citations
Semantic Scholar
Consensus recommendations for optimising the diagnosis and treatment of paroxysmal nocturnal haemoglobinuria in Singapore.
Y. Goh, E. Yap, Chuen W. Tan, Daryl Tan +5 more
2024Annals of the Academy of Medicine, Singapore7 citations Open access
Semantic Scholar
A cost-effectiveness analysis of ruxolitinib versus best alternative therapy for patients with steroid-refractory chronic graft-versus-host disease aged > 12 years in Singapore
J. C. Ong, H. Than, S. Tripathi, Christina Gkitzia +1 more
2023Cost Effectiveness and Resource Allocation6 citations Open access
Semantic Scholar
COORDINATED INHIBITION OF NUCLEAR EXPORT AND BCR-ABL1 SELECTIVELY TARGETS CHRONIC MYELOID LEUKEMIA STEM CELLS
H. Than, A. Pomicter, D. Yan, Larry P. Beaver +8 more
2020Leukemia6 citations Open access
Semantic Scholar
Abstract 1911: A common BIM polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer
S. Ong, K. Ng, A. Hillmer, C. Chuah +46 more
20126 citations
Semantic Scholar
Pegcetacoplan: the first and only C3-targeted therapy for the treatment of adults with paroxysmal nocturnal hemoglobinuria
Tze-Wei Chan, H. Than, T. Tuy, Y. Goh
2024Expert Review of Hematology5 citations Open access
Semantic Scholar
Ongoing Clonal Evolution in Chronic Myelomonocytic Leukemia on Hypomethylating Agents: A Computational Perspective
H. Than, Yi Qiao, Xiao-Meng Huang, D. Yan +6 more
2018Leukemia5 citations Open access
Semantic Scholar
Managing Myelofibrosis: Matching Advances in Treatments With Clinical Unmet Needs
Chan-Tze Wei, H. Than, Fei-Qiang Huang, Gauri Billa +1 more
2025Hematological Oncology4 citations Open access
Semantic Scholar
Tear Cytokine Changes up to One Year After Allogeneic Hematopoietic Stem Cell Transplant: Effect of Daily Topical Cyclosporine-A 0.1% Emulsion
Louis Tong, Yu-Chi Liu, Sharon Yeo, Chang Liu +8 more
2025International Journal of Molecular Sciences3 citations
Semantic Scholar
Fusion Genes in Myeloid Malignancies
C. Ang, H. Than, T. Tuy, Y. Goh
2024Cancers3 citations Open access
Semantic Scholar
A proposed predictive mathematical model for efficient T-cell collection by leukapheresis for manufacturing chimeric antigen receptor T cells
Xin-Xin Huang, Gina Gan, E. Chan, K. Heng +13 more
2023Haematologica3 citations Open access
Semantic Scholar
Combining the Allosteric ABL1 Inhibitor Asciminib (ABL001) with Ponatinib Suppresses Emergence of and Restores Efficacy Against Highly Resistant BCR-ABL1 Compound Mutants
C. Eide, M. Zabriskie, Samantha Savage, Orlando Antelope +20 more
2019Blood3 citations Open access
Semantic Scholar
SIRT5 As a Therapeutic Target in Acute Myeloid Leukemia
D. Yan, A. Pomicter, W. Heaton, C. C. Mason +9 more
2018Blood3 citations
Semantic Scholar
Rapid Disease Progression of Myelodysplastic Syndrome is Reflected in Transcriptomic and Functional Abnormalities of Bone Marrow MSCs.
H. Than, Xiubo Fan, A. Cheung, W. Hwang +1 more
2024Stem Cells2 citations
Semantic Scholar
Long-term survival and clinical implications of allogeneic stem cell transplantation in relapse/refractory lymphoma: A 20-year Singapore experience.
W. Loke, J. Catapia, C. L. Low, F. Lim +14 more
2024Annals of the Academy of Medicine, Singapore2 citations Open access
Semantic Scholar
Haploidentical Hematopoietic Cell Transplantation of Ex Vivo Tcrαβ-Depleted Grafts with CD45RA-Depleted Memory T Cell Add-Back Reduces Chronic Graft-Versus-Host Disease and Results in Favourable Gvhd-Relapse Free Survival: 5-Year Follow-up of 107 Patients Treated in a Multicenter Study in Singapore
L. Koh, M. Poon, J. Quek, L. Tan +22 more
2022Blood2 citations Open access
Semantic Scholar
Genetic Profiling Augments Prognostic Value of the EUTOS Long-Term Survival Score for Disease-Specific Mortality in Imatinib-Treated Asian Chronic Myeloid Leukaemia Patients
H. Than, W. Lye, C. H. Seow, Colin Sng +2 more
20162 citations
Semantic Scholar
Mefloquine Effectively Targets Blast Phase Chronic Myeloid Leukemia through Inducing Oxidative Stress and Lysosomal Disruption
Wei Xiang, Yi Lam, C. Sng, M. Cheong +3 more
20162 citations
Semantic Scholar
Clinical utility of anti-Xa monitoring and differential sensitivity of prothrombin time assays: an illustrated case report
H. Than, Joanna Loh, C. L. L. Sum, H. Ng
2015Journal of Clinical Pathology2 citations
Semantic Scholar
A Common Deletion Polymorphism in the BIM Gene Contributes to Intrinsic Imatinib Resistance in Chronic Myelogenous Leukemia
A. Hillmer, K. Ng, C. Chuah, Wen Chun Juan +32 more
20112 citations
Semantic Scholar
Upfront memory T cell add-back with haploidentical TCRαβ-depleted graft in adults with haematological malignancies: a nationwide, multicentre, single-arm, prospective study
L. Koh, Y. Linn, Y. L. Boo, Victor Ling +24 more
2025Bone Marrow Transplantation1 citations
Semantic Scholar
A formula using day 4 parameters to predict next-day peripheral blood stem cell yield in healthy haematopoietic stem cell donors
Jing Y. Tan, L. Koh, Y. Woon, K. Heng +21 more
2025Bone Marrow Transplantation1 citations
Semantic Scholar
BRIDGING RADIATION THERAPY IN CAR‐T THERAPY
T. Li, F. Lim, Y. Chen, C. Nagarajan +10 more
2025Hematological Oncology1 citations
Semantic Scholar
Impact of C‐MYC/BCL2 Double Expression on Survival Outcomes After Autologous Transplantation in Relapsed/Refractory Diffuse Large B Cell Lymphoma—A Nationwide Retrospective Analysis in Singapore
Jing Y. Tan, Victor Ling, L. C. K. Ng, Cindy Krisnadi +17 more
2024Hematological Oncology1 citations
Semantic Scholar
Co-Expression of C-MYC/BCL2 Is Associated with Inferior Survival Outcomes in Relapsed/Refractory Diffuse Large B-Cell Lymphoma after Autologous Stem Cell Transplantation - a Nationwide Retrospective Analysis in Singapore
Jing-Yuan Tan, Victor Ling Wei Teik, Cindy Krisnadi, L. Ng +17 more
2023Blood1 citations
Semantic Scholar
Daratumumab Bortezomib and Dexamethasone in Transplant Ineligible Newly Diagnosed Elderly Myeloma Patients - a Trial By Asian Myeloma Network
C. Nagarajan, M. Tan, Yun-Xin Chen, Melissa G. Ooi +7 more
2023Blood1 citations Open access
Semantic Scholar
Outcomes of B-Cell Acute Lymphoblastic Leukemia Patients Who Relapse after Blinatumomab Salvage Therapy - a Tertiary Centre Experience
Jing-Yuan Tan, Nurul Aidah Abdul Halim, C. Ang, T. Tuy +7 more
2023Blood1 citations Open access
Semantic Scholar
Transcriptomic Signature and Functional Abnormalities of Bone Marrow Mesenchymal Stromal Cells Mediate Disease Progression of Myelodysplastic/Myeloproliferative Neoplasms
Z. Poon, John Ouyang, A. Cheung, Xiubo Fan +3 more
2023Blood1 citations Open access
Semantic Scholar
Mobilization kinetics of peripheral blood stem cells with rescue plerixafor – real-world experience from a single center
Khaing-Shwe Wah Pwint, Yunxin Chen, C. Diong, Y. Goh +12 more
2020Leukemia and Lymphoma1 citations
Semantic Scholar
Inhibition of Nucleocytoplasmic Export Enhances Selective Elimination of Leukemic Stem Cells in Chronic Myeloid Leukemia
H. Than, A. Pomicter, C. C. Mason, A. Eiring +7 more
20171 citations
Semantic Scholar
Molecular Mechanism of TKI Resistance and Potential Approaches to Overcome Resistance
H. Than, C. Chuah, S. Ong
20161 citations
Semantic Scholar
Overcoming donor-specific anti-human leukocyte antigen antibodies with desensitisation in adult ex-vivo T-cell depleted haploidentical haematopoietic stem cell transplantation: a real-world analysis.
C. Tham, Y. Linn, L. P. Koh, C. Phang +10 more
2026Transplantation and Cellular Therapy0 citations Open access
Semantic Scholar
Autoimmune cytopenia after allogeneic haematopoietic stem cell transplantation - A single-center case series.
Ying-Qi Wang, Y. Goh, A. Ho, William Huang +4 more
2026Transplant Immunology0 citations
Semantic Scholar
Clinical Characteristics and Molecular Profiling of SF3B1-Mutated Myelodysplastic Syndrome (MDS) in a Real-World Practice
Ruonan Wang, H. Than, C. Tham, G. How +2 more
2026International Journal of Molecular Sciences0 citations Open access
Semantic Scholar
One-Year Tear Proteomic Alterations with Topical Cyclosporine-A 0.1% Emulsion in Patients with Allogeneic Stem Cell Transplant.
Chang Liu, Xin-Yue Wang, Sharon Yeo, Isabelle Xin Yu Lee +10 more
2025Transplantation and Cellular Therapy0 citations
Semantic Scholar

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