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Joana Smirnovienė · SciRah

Researcher profile · Semantic Scholar

Joana Smirnovienė

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Joana Smirnovienė — researcher profile on SciRah

h-index: 12
Works: 20
Citations: 377

Most-cited papers

Discovery and characterization of novel selective inhibitors of carbonic anhydrase IX.
V. Dudutienė, J. Matulienė, A. Smirnov, David D. Timm +30 more
2014Journal of Medicinal Chemistry87 citations Open access
Semantic Scholar
Intrinsic thermodynamics of 4-substituted-2,3,5,6-tetrafluorobenzenesulfonamide binding to carbonic anhydrases by isothermal titration calorimetry.
A. Zubrienė, Joana Smirnovienė, A. Smirnov, Vaida Morkūnaitė +7 more
2015Biophysical Chemistry61 citations
Semantic Scholar
Functionalization of Fluorinated Benzenesulfonamides and Their Inhibitory Properties toward Carbonic Anhydrases
V. Dudutienė, A. Zubrienė, A. Smirnov, David D. Timm +7 more
2015ChemMedChem39 citations
Semantic Scholar
Picomolar inhibitors of carbonic anhydrase: Importance of inhibition and binding assays.
Joana Smirnovienė, V. Smirnovas, D. Matulis
2017Analytical Biochemistry31 citations
Semantic Scholar
Intrinsic Thermodynamics and Structure Correlation of Benzenesulfonamides with a Pyrimidine Moiety Binding to Carbonic Anhydrases I, II, VII, XII, and XIII
M. Kišonaitė, A. Zubrienė, E. Čapkauskaitė, A. Smirnov +6 more
2014PLoS ONE25 citations Open access
Semantic Scholar
Synthesis and structure-affinity relationship of chlorinated pyrrolidinone-bearing benzenesulfonamides as human carbonic anhydrase inhibitors.
Benas Balandis, Guostė Ivanauskaitė, Joana Smirnovienė, K. Kantminienė +3 more
2020Bioorganic chemistry (Print)21 citations
Semantic Scholar
Intrinsic binding of 4‐substituted‐2,3,5,6‐tetrafluorobenezenesulfonamides to native and recombinant human carbonic anhydrase VI
Justina Kazokaitė, Goda Milinavičiūtė, Joana Smirnovienė, J. Matulienė +1 more
2015The FEBS Journal18 citations
Semantic Scholar
Engineered Carbonic Anhydrase VI-Mimic Enzyme Switched the Structure and Affinities of Inhibitors
Justina Kazokaitė, V. Kairys, Joana Smirnovienė, A. Smirnov +4 more
2019Scientific Reports16 citations Open access
Semantic Scholar
A standard operating procedure for an enzymatic activity inhibition assay
Joana Smirnovienė, L. Baranauskienė, A. Zubrienė, D. Matulis
2021European Biophysics Journal14 citations
Semantic Scholar
PLBD: protein–ligand binding database of thermodynamic and kinetic intrinsic parameters
D. Linge, M. Gedgaudas, Andrius Merkys, V. Petrauskas +19 more
2023Database J. Biol. Databases Curation13 citations Open access
Semantic Scholar
Picomolar fluorescent probes for compound affinity determination to carbonic anhydrase IX expressed in live cancer cells
J. Matulienė, Gediminas Žvinys, V. Petrauskas, A. Kvietkauskaitė +24 more
2022Scientific Reports13 citations Open access
Semantic Scholar
Isoform-Selective Enzyme Inhibitors by Exploring Pocket Size According to the Lock-and-Key Principle.
V. Dudutienė, A. Zubrienė, V. Kairys, A. Smirnov +7 more
2020Biophysical Journal12 citations Open access
Semantic Scholar
Volume of Hsp90 Protein-Ligand Binding Determined by Fluorescent Pressure Shift Assay, Densitometry, and NMR.
Zigmantas Toleikis, V. Sirotkin, Gediminas Skvarnavičius, Joana Smirnovienė +3 more
2016Journal of Physical Chemistry B10 citations
Semantic Scholar
Switching the Inhibitor‐Enzyme Recognition Profile via Chimeric Carbonic Anhydrase XII
Joana Smirnovienė, A. Smirnov, A. Zakšauskas, A. Zubrienė +10 more
2021ChemistryOpen8 citations Open access
Semantic Scholar
High pressure spectrofluorimetry – a tool to determine protein-ligand binding volume
Gediminas Skvarnavičius, Zigmantas Toleikis, M. Grigaliunas, Joana Smirnovienė +4 more
20175 citations Open access
Semantic Scholar
Sulfonamide Inhibitors of Amyloid Aggregation: A Promising Path against Neurodegenerative Diseases
Joana Smirnovienė, D. Matulis
2025ChemMedChem2 citations
Semantic Scholar
Experimental approaches to identify selective picomolar inhibitors for carbonic anhydrase IX.
Justina Kazokaitė-Adomaitienė, H. Becker, Joana Smirnovienė, L. Dubois +1 more
2020Current Medicinal Chemistry2 citations
Semantic Scholar
Intrinsic Thermodynamics - Structure Correlation of Carbonic Anhydrase Inhibitors
D. Matulis, A. Zubrienė, L. Baranauskienė, A. Smirnov +5 more
20150 citations Open access
Semantic Scholar
Differences in stability profiles and thermodynamics of inhibitor binding to target protein purified from E. coli, mammalian cells, and human saliva
Justina Kazokaitė, Goda Milinavičiūtė, Joana Smirnovienė, V. Dudutienė +3 more
20140 citations
Semantic Scholar
Switching inhibitor recognition by engineering isozymes of carbonic anhydrase
Joana Smirnovienė
0 citations
Semantic Scholar

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D. Matulis×19
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D. Matulis — researcher profile on SciRah
A. Zubrienė×11
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A. Zubrienė — researcher profile on SciRah
A. Smirnov×9
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S. Gražulis×7
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