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M. Highkin · SciRah

Researcher profile · Semantic Scholar

M. Highkin

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M. Highkin — researcher profile on SciRah

h-index: 17
Works: 27
Citations: 1,319

Most-cited papers

Modulation of cellular S1P levels with a novel, potent and specific inhibitor of sphingosine kinase-1.
M. Schnute, Matthew D. Mcreynolds, T. Kasten, M. Yates +20 more
2012Biochemical Journal271 citations
Semantic Scholar
Characterization of the Cytoprotective Action of Peroxynitrite Decomposition Catalysts*
T. P. Misko, M. Highkin, A. W. Veenhuizen, P. Manning +3 more
1998Journal of Biological Chemistry229 citations Open access
Semantic Scholar
Persistence of mouse hepatitis virus A59 RNA in a slow virus demyelinating infection in mice as detected by in situ hybridization
E. Lavi, D. Gilden, M. Highkin, Susan R. Weiss
1984Journal of Virology101 citations Open access
Semantic Scholar
The organ tropism of mouse hepatitis virus A59 in mice is dependent on dose and route of inoculation.
E. Lavi, D. Gilden, M. Highkin, S. Weiss
1986Laboratory animal science99 citations
Semantic Scholar
Limbic encephalitis after inhalation of a murine coronavirus.
E. Lavi, P. Fishman, M. Highkin, S. Weiss
1988Laboratory investigation; a journal of technical methods and pathology97 citations
Semantic Scholar
Infection of the basal ganglia by a murine coronavirus.
P. Fishman, J. S. Gass, P. Swoveland, E. Lavi +2 more
1985Science80 citations
Semantic Scholar
Coronavirus mouse hepatitis virus (MHV)-A59 causes a persistent, productive infection in primary glial cell cultures
E. Lavi, A. Suzumura, M. Hirayama, M. Highkin +3 more
1987Microbial Pathogenesis58 citations Open access
Semantic Scholar
Structure−Activity Relationship Studies on 1-[2-(4-Phenylphenoxy)ethyl]pyrrolidine (SC-22716), a Potent Inhibitor of Leukotriene A4 (LTA4) Hydrolase
Thomas D. Penning, Nizal S. Chandrakumar, Barbara B. Chen, Helen Y. Chen +23 more
200054 citations Open access
Semantic Scholar
Characterization of nitrotyrosine as a biomarker for arthritis and joint injury.
T. P. Misko, M. R. Radabaugh, M. Highkin, M. Abrams +6 more
2013Osteoarthritis and Cartilage46 citations Open access
Semantic Scholar
Discovery of a Potent and Selective Sphingosine Kinase 1 Inhibitor through the Molecular Combination of Chemotype-Distinct Screening Hits.
M. Schnute, Matthew D. Mcreynolds, Jeffrey Carroll, J. Chrencik +8 more
2017Journal of Medicinal Chemistry44 citations Open access
Semantic Scholar
Concurrent HER or PI3K Inhibition Potentiates the Anti-tumor Effect of ERK Inhibitor Ulixertinib in Preclinical Pancreatic Cancer Models
Hong-Mei Jiang, Mai Xu, Lin Li, P. Grierson +6 more
2018Molecular Cancer Therapeutics38 citations Open access
Semantic Scholar
Synthesis of potent leukotriene A(4) hydrolase inhibitors. Identification of 3-[methyl[3-[4-(phenylmethyl)phenoxy]propyl]amino]propanoic acid.
T. Penning, M. Russell, Barbara B. Chen, Helen Y. Chen +15 more
2002Journal of Medicinal Chemistry34 citations Open access
Semantic Scholar
High-Throughput Screening Assay for Sphingosine Kinase Inhibitors in Whole Blood Using RapidFire® Mass Spectrometry
M. Highkin, M. Yates, O. Nemirovskiy, W. Lamarr +4 more
2011Journal of biomolecular screening33 citations Open access
Semantic Scholar
Synthesis of imidazopyridines and purines as potent inhibitors of leukotriene A4 hydrolase.
T. Penning, N. Chandrakumar, B. N. Desai, S. Djuric +14 more
2003Bioorganic & Medicinal Chemistry Letters25 citations Open access
Semantic Scholar
High Level, Stable Production of Recombinant Proteins in Mammalian Cell Culture using the Herpesvirus VP16 Transactivator
P. Hippenmeyer, M. Highkin
1993Bio/Technology23 citations
Semantic Scholar
Structure-activity relationship studies on 1-[2-(4-Phenylphenoxy)ethyl]pyrrolidine (SC-22716), a potent inhibitor of leukotriene A(4) (LTA(4)) hydrolase.
T. Penning, N. Chandrakumar, B.-B. Chen, H.-Y. Chen +22 more
2000Journal of Medicinal Chemistry20 citations
Semantic Scholar
MHV-A59 pathogenesis in mice.
E. Lavi, D. Gilden, M. Highkin, Susan R. Weiss
1984Advances in Experimental Medicine and Biology18 citations Open access
Semantic Scholar
The herpesvirus protease: mechanistic studies and discovery of inhibitors of the human cytomegalovirus protease.
D. Flynn, D. P. Becker, V. M. Dilworth, M. Highkin +10 more
1997Drug Design and Discovery16 citations
Semantic Scholar
Pyrrolidine and piperidine analogues of SC-57461A as potent, orally active inhibitors of leukotriene A(4) hydrolase.
T. Penning, N. Chandrakumar, B. N. Desai, S. Djuric +14 more
2002Bioorganic & Medicinal Chemistry Letters10 citations Open access
Semantic Scholar
Phase II trial of levocetirizine with capecitabine and bevacizumab to overcome the resistance of antiangiogenic therapies in refractory metastatic colorectal cancer.
M. Amin, M. Desai, K. Trinkaus, Amberly Brown +7 more
2019Journal of Gastrointestinal Oncology8 citations Open access
Semantic Scholar
Abstract PS4-13: Irreversible inhibition of HER2 activating mutations with neratinib enhances the pre-clinical efficacy of trastuzumab emtansine and trastuzumab deruxtecan
R. Bose, Shun-Qiang Li, Tina M Primeau, M. Highkin +13 more
20217 citations
Semantic Scholar
Detection of MHV-A59 RNA by in situ hybridization.
E. Lavi, D. Gilden, M. Highkin, Susan R. Weiss
1984Advances in Experimental Medicine and Biology6 citations Open access
Semantic Scholar
Abstract 2375: Concurrent HER or PI3K inhibition potentiates the anti-tumor effect of ERK inhibitor BVD-523 (ulixertinib) in preclinical pancreatic cancer models
Hong-Mei Jiang, Mai Xu, Lin Li, M. Highkin +4 more
2018Molecular and Cellular Biology / Genetics2 citations
Semantic Scholar
FRI0046 Characterization of nitrotyrosine as a clinical biomarker for arthritis and joint injury
T. P. Misko, M. R. Radabaugh, M. Highkin, M. Abrams +7 more
20130 citations
Semantic Scholar
O28. NO biomarkers: Windows to NO-mediated pathology and therapeutic intervention
T. P. Misko, O. Nemirovskiy, M. Radabaugh, P. Aggarwal +6 more
20060 citations
Semantic Scholar
Production of recombinant proteins using herpesviruspromotorer and VP16 transactivators
M. Highkin, P. Hippenmeyer
19930 citations
Semantic Scholar
Production of recombinant proteins using herpes virus promoters and VP16 transactivation activators
M. Highkin, P. Hippenmeyer
19930 citations
Semantic Scholar

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