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Xin-Yan Wu · SciRah

Researcher profile · Semantic Scholar

Xin-Yan Wu

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Xin-Yan Wu — researcher profile on SciRah

h-index: 25
Works: 60
Citations: 4,101

Most-cited papers

A draft map of the human proteome
Min-Sik Kim, Sneha M. Pinto, D. Getnet, R. Nirujogi +68 more
2014Nature2,167 citations Open access
Semantic Scholar
HOXB7, a homeodomain protein, is overexpressed in breast cancer and confers epithelial-mesenchymal transition.
Xin-Yan Wu, He-Xin Chen, B. Parker, Ethel Rubin +4 more
2006Cancer Research215 citations Open access
Semantic Scholar
SLITs Suppress Tumor Growth In vivo by Silencing Sdf1/Cxcr4 within Breast Epithelium
Rebecca Marlow, Phyllis A. Strickland, Ji-Shin Lee, Xin-Yan Wu +8 more
2008Cancer Research131 citations Open access
Semantic Scholar
The HOXB7 protein renders breast cancer cells resistant to tamoxifen through activation of the EGFR pathway
Kideok Jin, X. Kong, T. Shah, Marie-France Penet +13 more
2011Proceedings of the National Academy of Sciences of the United States of America126 citations Open access
Semantic Scholar
A role for the HOXB7 homeodomain protein in DNA repair.
Ethel Rubin, Xin-Yan Wu, T. Zhu, Joyce C. Y. Cheung +9 more
2007Cancer Research107 citations Open access
Semantic Scholar
Epithelial cell adhesion molecule (EpCAM) is overexpressed in breast cancer metastases
Ashley M. Cimino, M. Halushka, P. Illei, Xin-Yan Wu +2 more
2009Breast Cancer Research and Treatment103 citations Open access
Semantic Scholar
BioSITe: A Method for Direct Detection and Quantitation of Site-Specific Biotinylation
Dae In Kim, J. Cutler, C. Na, S. Reckel +10 more
2017Journal of Proteome Research89 citations Open access
Semantic Scholar
Activation of diverse signaling pathways by oncogenic PIK3CA mutations
Xin-Yan Wu, S. Renuse, Nandini A. Sahasrabuddhe, M. S. Zahari +21 more
2014Nature Communications80 citations Open access
Semantic Scholar
HOXA5 acts directly downstream of retinoic acid receptor beta and contributes to retinoic acid-induced apoptosis and growth inhibition.
He-Xin Chen, Huiping Zhang, Jishin Lee, Xiaohui Liang +5 more
2007Cancer Research76 citations Open access
Semantic Scholar
TSLP Signaling Network Revealed by SILAC-Based Phosphoproteomics*
J. Zhong, Min-Sik Kim, Raghothama Chaerkady, Xin-Yan Wu +14 more
2012Molecular & Cellular Proteomics63 citations Open access
Semantic Scholar
Quantitative Phosphoproteomics Reveals Crosstalk Between Phosphorylation and O-GlcNAc in the DNA Damage Response Pathway
J. Zhong, Marissa R Martinez, Srona Sengupta, Albert Lee +7 more
2015Proteomics62 citations Open access
Semantic Scholar
Phosphoproteomic Profiling Reveals Epstein-Barr Virus Protein Kinase Integration of DNA Damage Response and Mitotic Signaling
Ren-Feng Li, Gangling Liao, R. Nirujogi, Sneha M. Pinto +11 more
2015PLoS Pathogens61 citations Open access
Semantic Scholar
The Preferred Locations of Meningioma According to Different Biological Characteristics Based on Voxel-Wise Analysis
Chong-Ran Sun, Zhangqi Dou, Jiawei Wu, B. Jiang +12 more
2020Frontiers in Oncology59 citations Open access
Semantic Scholar
AXL kinase-mediated astrocytic phagocytosis modulates outcomes of traumatic brain injury
Hang Zhou, Li-bin Hu, Jian-Ru Li, Wu Ruan +16 more
2021Journal of Neuroinflammation53 citations Open access
Semantic Scholar
Global phosphotyrosine survey in triple-negative breast cancer reveals activation of multiple tyrosine kinase signaling pathways
Xin-Yan Wu, M. S. Zahari, B. Ma, Ren Liu +23 more
2015OncoTarget48 citations Open access
Semantic Scholar
TREM1 Regulates Neuroinflammatory Injury by Modulate Proinflammatory Subtype Transition of Microglia and Formation of Neutrophil Extracellular Traps via Interaction With SYK in Experimental Subarachnoid Hemorrhage
Xin-Yan Wu, Han-Hai Zeng, Chao-Ran Xu, Huai-Jun Chen +8 more
2021Frontiers in Immunology45 citations Open access
Semantic Scholar
A multi-omic analysis of human naïve CD4+ T cells
Christopher J. Mitchell, D. Getnet, Min-Sik Kim, Srikanth S. Manda +31 more
2015BMC Systems Biology44 citations Open access
Semantic Scholar
The non-receptor tyrosine kinase TNK2/ACK1 is a novel therapeutic target in triple negative breast cancer
Xin-Yan Wu, M. S. Zahari, S. Renuse, Dhanashree S. Kelkar +8 more
2016OncoTarget42 citations Open access
Semantic Scholar
The Role of the Blood Neutrophil-to-Lymphocyte Ratio in Aneurysmal Subarachnoid Hemorrhage
Lingxin Cai, Han-Hai Zeng, Xiao-Xia Tan, Xin-Yan Wu +2 more
2021Frontiers in Neurology41 citations Open access
Semantic Scholar
Neutrophil to lymphocyte ratio predicting poor outcome after aneurysmal subarachnoid hemorrhage: A retrospective study and updated meta-analysis
Ying-Han Guo, Jiang Liu, Han-Hai Zeng, Lingxin Cai +10 more
2022Frontiers in Immunology31 citations Open access
Semantic Scholar
Inhibition of P2X4R attenuates white matter injury in mice after intracerebral hemorrhage by regulating microglial phenotypes
Xiong-Jie Fu, Guoyang Zhou, Xin-Yan Wu, Chao-Ran Xu +11 more
2021Journal of Neuroinflammation31 citations Open access
Semantic Scholar
The impact of concurrent bacterial lung infection on immunotherapy in patients with non-small cell lung cancer: a retrospective cohort study
Qiang Cao, Xin-Yan Wu, Yuquan Chen, Qiong-peng Wei +3 more
2023Frontiers in Cellular and Infection Microbiology29 citations Open access
Semantic Scholar
Serial analysis of gene expression of lobular carcinoma in situ identifies down regulation of claudin 4 and overexpression of matrix metalloproteinase 9
D. Cao, K. Polyak, M. Halushka, H. Nassar +7 more
2008Breast Cancer Research28 citations Open access
Semantic Scholar
Endothelial Scaffolding Protein ENH (Enigma Homolog Protein) Promotes PHLPP2 (Pleckstrin Homology Domain and Leucine-Rich Repeat Protein Phosphatase 2)-Mediated Dephosphorylation of AKT1 and eNOS (Endothelial NO Synthase) Promoting Vascular Remodeling
Jia-Qi Huang, Changhong Cai, Tianyu Zheng, Xin-Yan Wu +21 more
2020Arteriosclerosis, Thrombosis and Vascular Biology27 citations Open access
Semantic Scholar
Global Effects of DDX3 Inhibition on Cell Cycle Regulation Identified by a Combined Phosphoproteomics and Single Cell Tracking Approach
Marise R. Heerma van Voss, K. Kammers, F. Vesuna, Justin Brilliant +7 more
2018Translational Oncology27 citations Open access
Semantic Scholar
Epigenetic reprogramming of cell cycle genes by ACK1 promotes breast cancer resistance to CDK4/6 inhibitor
Mithila Sawant, Audrey Wilson, Dhivya Sridaran, Kiran Mahajan +9 more
2023Oncogene25 citations Open access
Semantic Scholar
Metformin Alleviates Neuroinflammation Following Intracerebral Hemorrhage in Mice by Regulating Microglia/Macrophage Phenotype in a Gut Microbiota-Dependent Manner
Xiao-Bo Yu, Xiong-Jie Fu, Xin-Yan Wu, Wenwen Tang +12 more
2022Frontiers in Cellular Neuroscience24 citations Open access
Semantic Scholar
Phosphoproteomic Analysis Identifies Focal Adhesion Kinase 2 (FAK2) as a Potential Therapeutic Target for Tamoxifen Resistance in Breast Cancer*
Xin-Yan Wu, M. S. Zahari, S. Renuse, R. Nirujogi +6 more
2015Molecular & Cellular Proteomics24 citations Open access
Semantic Scholar
HOXB 7 , a Homeodomain Protein , Is Overexpressed in Breast Cancer and Confers Epithelial-Mesenchymal Transition
Xin-Yan Wu, He-Xin Chen, B. Parker, Ethel Rubin +4 more
200623 citations
Semantic Scholar
DJ-1 Alleviates Neuroinflammation and the Related Blood-Spinal Cord Barrier Destruction by Suppressing NLRP3 Inflammasome Activation via SOCS1/Rac1/ROS Pathway in a Rat Model of Traumatic Spinal Cord Injury
Lingxin Cai, Lian-Sheng Gao, Guoqiang Zhang, Han-Hai Zeng +4 more
2022Journal of Clinical Medicine22 citations Open access
Semantic Scholar
Mutation-specific and common phosphotyrosine signatures of KRAS G12D and G13D alleles.
Raiha Tahir, S. Renuse, Savita Udainiya, Anil K. Madugundu +6 more
2020Journal of Proteome Research19 citations
Semantic Scholar
Role of the Extracellular Traps in Central Nervous System
Xin-Yan Wu, Han-Hai Zeng, Lingxin Cai, Gao Chen
2021Frontiers in Immunology18 citations Open access
Semantic Scholar
ADP Ribosylation by PARP-1 Suppresses HOXB7 Transcriptional Activity
Xin-Yan Wu, S. Ellmann, Ethel Rubin, M. Gil +7 more
2012PLoS ONE16 citations Open access
Semantic Scholar
Signature Fragment Ions of Biotinylated Peptides
S. Renuse, Anil K. Madugundu, J. Jung, Seul Kee Byeon +9 more
2020Journal of the American Society for Mass Spectrometry15 citations Open access
Semantic Scholar
Quantitative phosphoproteomic analysis reveals reciprocal activation of receptor tyrosine kinases between cancer epithelial cells and stromal fibroblasts
Xin-Yan Wu, M. S. Zahari, S. Renuse, Nandini A. Sahasrabuddhe +7 more
2018Clinical Proteomics15 citations Open access
Semantic Scholar
Integrative phosphoproteome and interactome analysis of the role of Ubash3b in BCR-ABL signaling
J. Cutler, Savita Udainiya, Anil K. Madugundu, S. Renuse +5 more
2019Leukemia14 citations Open access
Semantic Scholar
A phosphoproteomic screen demonstrates differential dependence on HER3 for MAP kinase pathway activation by distinct PIK3CA mutations
Brian G. Blair, Xin-Yan Wu, M. S. Zahari, M. Mohseni +11 more
2014Proteomics14 citations Open access
Semantic Scholar
Phosphoproteomic profiling of tumor tissues identifies HSP27 Ser82 phosphorylation as a robust marker of early ischemia
M. S. Zahari, Xin-Yan Wu, Sneha M. Pinto, R. Nirujogi +8 more
2015Scientific Reports13 citations Open access
Semantic Scholar
Activating Mutations in PIK3CA Lead to Widespread Modulation of the Tyrosine Phosphoproteome
M. S. Zahari, Xin-Yan Wu, Brian G. Blair, Sneha M. Pinto +6 more
2015Journal of Proteome Research12 citations Open access
Semantic Scholar
DNase-1 Treatment Exerts Protective Effects in Neurogenic Pulmonary Edema via Regulating the Neutrophil Extracellular Traps after Subarachnoid Hemorrhage in Mice
Xin-Yan Wu, Ying-Han Guo, Han-Hai Zeng, Gao Chen
2022Journal of Clinical Medicine11 citations Open access
Semantic Scholar
Quantitative Tyrosine Phosphoproteome Profiling of AXL Receptor Tyrosine Kinase Signaling Network
Xin-Yan Wu, Li Wang, Nicole A. Pearson, S. Renuse +7 more
2021Cancers11 citations Open access
Semantic Scholar
A breast cancer cell microarray (CMA) as a rapid method to characterize candidate biomarkers
Xin-Yan Wu, M. S. Zahari, S. Renuse, Harrys K. C. Jacob +5 more
2014Cancer Biology & Therapy10 citations Open access
Semantic Scholar
Characterization of Lipid Alterations by Oncogenic PIK3CA Mutations Using Untargeted Lipidomics in Breast Cancer
Jaehun Jung, Da-Qing Yang, Hong-Ming Song, Xiangyu Wang +4 more
2023Omics9 citations Open access
Semantic Scholar
Proximity-dependent biotinylation to elucidate the interactome of TNK2 non-receptor tyrosine kinase
Raiha Tahir, Anil K. Madugundu, Savita Udainiya, J. Cutler +7 more
2021bioRxiv7 citations Open access
Semantic Scholar
Identification of spleen tyrosine kinase as a potential therapeutic target for esophageal squamous cell carcinoma using reverse phase protein arrays
M. A. Barbhuiya, M. Kashyap, Vinuth N. Puttamallesh, Rekha V. Kumar +3 more
2018OncoTarget5 citations Open access
Semantic Scholar
Integrating network pharmacology analysis and pharmacodynamic evaluation for exploring the active components and molecular mechanism of moutan seed coat extract to improve cognitive impairment
Yue Wang, Xin-Yan Wu, Kailin Yang, Qing Liu +4 more
2022Frontiers in Pharmacology4 citations Open access
Semantic Scholar
Strategy of De Novo Design toward First-In-Class Imaging Agents for Simultaneously Differentiating Glioma Boundary and Grades.
Feng Yan, Jian-Feng Zhuang, Qian Yu, Zhangqi Dou +11 more
2021ACS Sensors2 citations
Semantic Scholar
Post-translation regulation inhibits Claudin-7 expression in invasive breast cancer cells.
Xin-Yan Wu, Liang-Feng Han, S. Kominsky, S. Sukumar
20051 citations
Semantic Scholar
Induction of epithelial-mesenchymal transition of MCF-10A cells with high expression of HOXB7.
Xin-Yan Wu, Ethel Rubin, T. Zhu, B. Parker +1 more
20041 citations
Semantic Scholar
Abstract P3-11-04: Endoxifen Downregulates AKT Phosphorylation Through Protein Kinase C Beta 1 in ER+/HER2- Breast Cancer
S. Jayaraman, Xin-Yan Wu, K. Kalari, Xiao-Jia Tang +9 more
2023Cancer Research0 citations
Semantic Scholar

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