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Charles W. Johannes · SciRah

Researcher profile · Semantic Scholar

Charles W. Johannes

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Charles W. Johannes — researcher profile on SciRah

h-index: 21
Works: 60
Citations: 1,419

Most-cited papers

bioPROTACs as versatile modulators of intracellular therapeutic targets including proliferating cell nuclear antigen (PCNA)
Shu-Hui Lim, R. Khoo, Khong Ming Peh, Jin-Kai Teo +9 more
2020Proceedings of the National Academy of Sciences of the United States of America148 citations Open access
Semantic Scholar
Zr-Catalyzed Kinetic Resolution of Allylic Ethers and Mo-Catalyzed Chromene Formation in Synthesis. Enantioselective Total Synthesis of the Antihypertensive Agent (S,R,R,R)-Nebivolol
Charles W. Johannes, Michael Visser, A. Hoveyda
1998133 citations
Semantic Scholar
Applications of Zr-Catalyzed Carbomagnesation and Mo-Catalyzed Macrocyclic Ring Closing Metathesis in Asymmetric Synthesis. Enantioselective Total Synthesis of Sch 38516 (Fluvirucin B1)
Zhong-Ming Xu, Charles W. Johannes, A. Houri, Daniel S. La +3 more
199786 citations
Semantic Scholar
Natural product-like synthetic libraries.
Gemma L. Thomas, Charles W. Johannes
2011Current Opinion in Chemical Biology78 citations
Semantic Scholar
In vitro and in vivo anticancer activities of synthetic (-)-laulimalide, a marine natural product microtubule stabilizing agent.
Jun-Ke Liu, M. Towle, H. Cheng, P. Saxton +12 more
2007Anticancer Research72 citations
Semantic Scholar
Enantioselective Total Synthesis of Antifungal Agent Sch 38516
Zhong-Ming Xu, Charles W. Johannes, Sarri S. Salman, A. Hoveyda
199671 citations
Semantic Scholar
A new organocatalyst for 1,3-dipolar cycloadditions of nitrones to α,β-unsaturated aldehydes
San-San Chow, Marta Nevalainen, C. A. Evans, Charles W. Johannes
200768 citations
Semantic Scholar
Tandem oxidative amidation of benzyl alcohols with amine hydrochloride salts catalysed by iron nitrate
S. Ghosh, Joyce S. Y. Ngiam, A. Seayad, T. Dang +2 more
201353 citations
Semantic Scholar
Synthesis and biological evaluation of (-)-laulimalide analogues.
Brian M. Jr. Gallagher, Francis G. Fang, Charles W. Johannes, Marc Pesant +6 more
2004Bioorganic & Medicinal Chemistry Letters51 citations
Semantic Scholar
Macrocyclic α helical peptide therapeutic modality: A perspective of learnings and challenges.
T. Sawyer, A. Partridge, H. Y. K. Kaan, Juang Yu-Chi +19 more
2018Bioorganic & Medicinal Chemistry50 citations
Semantic Scholar
Enantio-, Diastereo-, and Regioselective Zirconium-Catalyzed Carbomagnesation of Cyclic Ethers with Higher Alkyls of Magnesium. Utility in Synthesis and Mechanistic Implications
M. Didiuk, Charles W. Johannes, J. Morken, A. Hoveyda
199543 citations
Semantic Scholar
Direct conversion of indoles to 3,3-difluoro-2-oxindoles via electrophilic fluorination.
Y. Lim, Qunxiang Ong, Hung A. Duong, T. Nguyen +1 more
2012Organic Letters42 citations Open access
Semantic Scholar
NanoClick: A High Throughput, Target-Agnostic Peptide Cell Permeability Assay.
A. Peier, Lan Ge, Nicolas Boyer, J. Frost +21 more
2021ACS Chemical Biology41 citations
Semantic Scholar
Incorporation of Putative Helix-Breaking Amino Acids in the Design of Novel Stapled Peptides: Exploring Biophysical and Cellular Permeability Properties
A. Partridge, H. Y. K. Kaan, Juang Yu-Chi, Ahmad Sadruddin +19 more
2019Molecules40 citations Open access
Semantic Scholar
Diversity-oriented synthesis of a cytisine-inspired pyridone library leading to the discovery of novel inhibitors of Bcl-2.
L. Marcaurelle, Charles W. Johannes, D. Yohannes, B. Tillotson +1 more
2009Bioorganic & Medicinal Chemistry Letters39 citations Open access
Semantic Scholar
Application of natural product-inspired diversity-oriented synthesis to drug discovery.
L. Marcaurelle, Charles W. Johannes
2008Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques34 citations
Semantic Scholar
A new route to bicyclo[1.1.1]pentan-1-amine from 1-azido-3-iodobicyclo[1.1.1]pentane.
Yi-Ling Goh, E. Tam, P. Bernardo, C. Cheong +3 more
2014Organic Letters32 citations
Semantic Scholar
De-risking drug discovery of intracellular targeting peptides: screening strategies to eliminate false-positive hits
Simon Ng, Juang Yu-Chi, Arun Chandramohan, Hung Yi Kristal Kaan +16 more
2019bioRxiv26 citations Open access
Semantic Scholar
Discovery of cell active macrocyclic peptides with on-target inhibition of KRAS signaling
Shu-Hui Lim, Nicolas Boyer, Nicole Boo, Chunhui Huang +29 more
2021bioRxiv23 citations Open access
Semantic Scholar
Intranasal administration of a stapled relaxin‐3 mimetic has anxiolytic‐ and antidepressant‐like activity in rats
Subhi Marwari, A. Poulsen, N. Shih, R. Lakshminarayanan +4 more
2019British Journal of Pharmacology21 citations Open access
Semantic Scholar
Palladium-meta-terarylphosphine catalyst for the Mizoroki-Heck reaction of (hetero)aryl bromides and functional olefins.
Daniel Weiliang Tay, Howard Jong, Y. Lim, Wen-Qin Wu +3 more
2015Journal of Organic Chemistry21 citations
Semantic Scholar
Macrocyclization of an all-d linear α-helical peptide imparts cellular permeability† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9sc06383h
S. Kannan, Pietro G. A. Aronica, Simon Ng, Dawn Thean Gek Lian +22 more
2020Chemical Science20 citations Open access
Semantic Scholar
A Versatile and Efficient Palladium–meta‐Terarylphosphine Catalyst for the Copper‐Free Sonogashira Coupling of (Hetero‐)Aryl Chlorides and Alkynes
Yong Yang, Xin-Ying Chew, Charles W. Johannes, E. Robins +2 more
201420 citations
Semantic Scholar
Cascade fluorofunctionalisation of 2,3-unsubstituted indoles by means of electrophilic fluorination.
T. Nguyen, Hung A. Duong, Jean-Alexandre Richard, Charles W. Johannes +3 more
2013Chemical Communications20 citations
Semantic Scholar
Mechanistic Insights and Implications of Dearomative Rearrangement in Copper-Free Sonogashira Cross-Coupling Catalyzed by Pd-Cy*Phine
A. Mak, Y. Lim, Howard Jong, Yong Yang +3 more
201619 citations Open access
Semantic Scholar
Palladium precatalysts containing meta-terarylphosphine ligands for expedient copper-free Sonogashira cross-coupling reactions
Yong Yang, Joyce Lim, Xin-Ying Chew, E. Robins +3 more
201516 citations
Semantic Scholar
Synthesis of amino sugars through a highly diastereoselective dipolar cycloaddition. Enantioselective synthesis of the carbohydrate segment of Sch 38516
Zhong-Ming Xu, Charles W. Johannes, Daniel S. La, Gloria E. Hofilena +1 more
199716 citations
Semantic Scholar
Stereoisomerism of stapled peptide inhibitors of the p53-Mdm2 interaction: an assessment of synthetic strategies and activity profiles
Tsz-Ying Yuen, C. Brown, Yue-Zhen Xue, Y. S. Tan +9 more
2019Chemical Science14 citations Open access
Semantic Scholar
One‐Pot Palladium‐Catalyzed Cross‐Coupling Treble of Borylation, the Suzuki Reaction and Amination
Howard Jong, Stanley T.‐C. Eey, Y. Lim, S. Pandey +4 more
201713 citations
Semantic Scholar
Stabilized Wittig olefination for bioconjugation.
Kenneth M. Lum, V. J. Xavier, Michelle Jui Hsien Ong, Charles W. Johannes +1 more
2013Chemical Communications13 citations
Semantic Scholar
Decarboxylative/Sonogashira-type cross-coupling using PdCl2(Cy*Phine)2
Yong Yang, Y. Lim, E. Robins, Charles W. Johannes
201612 citations
Semantic Scholar
Synthesis of 3-fluoro-2-hetarylindoles and 3,3-difluoro-2-hetarylindolines through Lewis acid-catalyzed formation of 3,3-difluoroindolium ions
J. Fong, S. Choo, Jean-Alexandre Richard, M. Garland +3 more
201512 citations
Semantic Scholar
Synthesis of Chiral Alkenyl Cyclopropane Amino Acids for Incorporation into Stapled Peptides.
Tsz-Ying Yuen, C. Brown, Y. S. Tan, Charles W. Johannes
2019Journal of Organic Chemistry9 citations
Semantic Scholar
Palladium-catalyzed decarboxylative cross-coupling of 3-pyridyl and 4-pyridyl carboxylates with aryl bromides
L. R. Chennamaneni, A. William, Charles W. Johannes
20159 citations
Semantic Scholar
Liposome Click Membrane Permeability Assay for Identifying Permeable Peptides
T. Desai, Bahanu Habulihaz, Joe R. Cannon, Arun Chandramohan +11 more
2021Pharmaceutical Research8 citations
Semantic Scholar
Expedient synthesis of bicyclo[3.2.1]octanes and bicyclo[3.3.1]nonanes via the double Michael addition to cyclic dienones
Aurélie Moulia, Joycelyn Teo, Charles W. Johannes, Jean-Alexandre Richard
20137 citations
Semantic Scholar
An intramolecular tryptophan-condensation approach for peptide stapling.
Eunice Y.-L. Hui, Bhimsen Rout, Y. S. Tan, C. Verma +2 more
2018Organic and biomolecular chemistry6 citations Open access
Semantic Scholar
Empirical and Computational Insights into N-Arylation Reactions Catalyzed by Palladium meta-Terarylphosphine Catalyst.
F. Yong, A. Mak, Wen-Qin Wu, M. Sullivan +4 more
2017ChemPlusChem6 citations
Semantic Scholar
A high‐throughput microfluidic mechanoporation platform to enable intracellular delivery of cyclic peptides in cell‐based assays
S. Kasper, S. Otten, Brian Squadroni, Cionna Orr‐Terry +19 more
2023Bioengineering & Translational Medicine5 citations Open access
Semantic Scholar
One-pot Suzuki–Heck relay to prepare industrially valuable intermediates using the Pd–Cy*Phine catalyst system
U. Das, Roxanne Clément, Charles W. Johannes, E. Robins +2 more
20175 citations
Semantic Scholar
Improved synthesis of pyridyl–biaryl ring systems via benzidine rearrangements
G. Y. C. Leung, A. William, Charles W. Johannes
20145 citations
Semantic Scholar
A New Organocatalyst for 1,3‐Dipolar Cycloadditions of Nitrones to α,β‐Unsaturated Aldehydes.
San-San Chow, Marta Nevalainen, C. A. Evans, Charles W. Johannes
20075 citations
Semantic Scholar
Synthesis of an octahydroindolinone scaffold for a diversity-based chemical compound library
G. Keaney, Charles W. Johannes
20074 citations
Semantic Scholar
Zr‐Catalyzed Kinetic Resolution of Allylic Ethers and Mo‐Catalyzed Chromene Formation in Synthesis. Enantioselective Total Synthesis of the Antihypertensive Agent (S,R,R,R)‐Nebivolol.
Charles W. Johannes, Michael Visser, A. Hoveyda
19992 citations
Semantic Scholar
Design-Rules for Stapled Alpha-Helical Peptides with On-Target In Vivo Activity: Application to Mdm2/X dual antagonists
Arun Chandramohan, H. Josien, Tsz-Ying Yuen, Ruchia Duggal +22 more
2023bioRxiv1 citations Open access
Semantic Scholar
A Versatile and Efficient Palladium-meta-Terarylphosphine Catalyst for the Copper-Free Sonogashira Coupling of (Hetero-)Aryl Chlorides and Alkynes.
Yong Yang, Xin-Ying Chew, Charles W. Johannes, E. Robins +2 more
20151 citations
Semantic Scholar
Enantioselective Total Synthesis of Antifungal Agent Sch 38516.
Z. Xu, Charles W. Johannes, Sarri S. Salman, A. Hoveyda
19971 citations
Semantic Scholar
Correction to: Liposome Click Membrane Permeability Assay for Identifying Permeable Peptides
T. Desai, Bahanu Habulihaz, Joe R. Cannon, Arun Chandramohan +11 more
2021Pharmaceutical Research0 citations Open access
Semantic Scholar
Supporting Information Macrocyclization of an all-D linear α-helical peptide imparts cellular permeability
S. Kannan, Pietro G. A. Aronica, Simon Ng, D. Lian +27 more
20200 citations
Semantic Scholar
bioPROTACs as versatile modulators of intracellular therapeutic targets: Application to proliferating cell nuclear antigen (PCNA)
Shu-Hui Lim, R. Khoo, Khong Ming Peh, Jin-Kai Teo +9 more
2019bioRxiv0 citations Open access
Semantic Scholar

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