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S. Ogbagabriel · SciRah

Researcher profile · Semantic Scholar

S. Ogbagabriel

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S. Ogbagabriel — researcher profile on SciRah

h-index: 8
Works: 18
Citations: 232

Most-cited papers

Securin is overexpressed in breast cancer
S. Ogbagabriel, Manory A. Fernando, F. Waldman, S. Bose +1 more
2005Modern Pathology56 citations
Semantic Scholar
Tumor penetration and epidermal growth factor receptor saturation by panitumumab correlate with antitumor activity in a preclinical model of human cancer
D. Freeman, K. McDorman, S. Ogbagabriel, C. Kozlosky +6 more
2012Molecular Cancer33 citations Open access
Semantic Scholar
Fully human Anti-HER3 monoclonal antibodies (mAbs) have unique in vitro and in vivo functional and antitumor activities versus other HER family inhibitors
D. Freeman, S. Ogbagabriel, M. Rothe, R. Radinsky +1 more
200827 citations
Semantic Scholar
Panitumumab and cetuximab epitope mapping and in vitro activity
D. Freeman, Ji-Lin Sun, R. Bass, K. Jung +3 more
200823 citations
Semantic Scholar
Activity of panitumumab alone or with chemotherapy in non-small cell lung carcinoma cell lines expressing mutant epidermal growth factor receptor
D. Freeman, T. Bush, S. Ogbagabriel, B. Belmontes +5 more
2009Molecular Cancer Therapeutics21 citations Open access
Semantic Scholar
Fully human Anti-HER3 monoclonal antibodies (mAbs) inhibit oncogenic signaling and tumor cell growth in vitro and in vivo
M. Treder, S. Hartmann, S. Ogbagabriel, E. Borges +5 more
200819 citations
Semantic Scholar
309 POSTER Fully human anti-HER3 mAb U3-1287 (AMG 888) demonstrates unique in vitro and in vivo activities versus other HER family inhibitors in NSCLC models
M. Treder, S. Ogbagabriel, R. Moor, U. Schulze-Horsel +4 more
200817 citations
Semantic Scholar
Abstract A182: U3–1287 (AMG 888), a fully human anti-HER3 mAb, demonstrates in vitro and in vivo efficacy in the FaDu model of human squamous cell carcinoma of the head and neck (SCCHN).
D. Freeman, S. Ogbagabriel, J. Bready, Ji-Rong Sun +2 more
201111 citations
Semantic Scholar
Abstract B167: Identifying first in human (FIH) doses and schedule of U3‐1287 (AMG 888), a fully human anti‐HER3 mAb, based on preclinical pharmacokinetic (PK), pharmacodynamic (PD) and efficacy data
Peggy Lum, J. P. Ruixo, S. Ogbagabriel, S. Doshi +5 more
20098 citations
Semantic Scholar
Abstract LB-306: U3-1287 (AMG 888), a fully human anti-HER3 mAb, inhibits HER3 activation and induces HER3 internalization and degradation
T. Hettmann, Matthias Schneider, S. Ogbagabriel, Jian-Song Xie +4 more
20104 citations
Semantic Scholar
Abstract B171: U3‐1287 (AMG 888), a fully human anti‐HER3 mAb, demonstrates in vitro and in vivo efficacy in NSCLC models
D. Freeman, S. Ogbagabriel, Matthias Schneider, R. Radinsky +1 more
20094 citations
Semantic Scholar
Heregulin expression level as a predictive biomarker for patritumab efficacy.
Matthias Schneider, S. Blum, C. Wenzl, J. Bange +3 more
20143 citations
Semantic Scholar
Abstract B161: U3‐1287 (AMG 888), a fully human anti‐HER3 mAb, demonstrates preclinical efficacy in HER2+ and HER2− breast cancer models
Thore Hettman, Matthias Schneider, S. Blum, S. Hartmann +5 more
20093 citations
Semantic Scholar
Tumor penetration and epidermal growth factor receptor saturation by panitumumab correlate with antitumor activity in a preclinical model of human cancer
D. Freeman, K. McDorman, S. Ogbagabriel, C. Kozlosky +6 more
2012Molecular Cancer1 citations Open access
Semantic Scholar
Mechanisms mediating the negative interaction between oxaliplatin (Ox) and epidermal growth factor receptor (EGFR) inhibitors in patients (pts) with KRAS mutant (MT) colorectal cancer (CRC).
D. Freeman, S. Ogbagabriel, Jian-Song Xie, Gloria Juan +3 more
20121 citations
Semantic Scholar
Epitope mapping and eludication of the mechanism of action of panitumumab, a fully human monoclonal antibody targeting the epidermal growth factor receptor (EGFR)
D. Freeman, Ji-Lin Sun, R. Bass, K. Chong +3 more
20071 citations
Semantic Scholar
P-0199 Mechanisms Mediating The Negative Interaction Between Oxaliplatin and Epidermal Growth Factor Receptor Inhibitors in Patients With KRAS Mutant Colorectal Cancer
D. Freeman, S. Ogbagabriel, Jian-Song Xie, Juan Gloria +3 more
20120 citations Open access
Semantic Scholar
Abstract A150: Molecular mechanisms mediating the pharmacodynamic interactions between oxaliplatin (Ox) and epidermal growth factor receptor (EGFR) inhibitors in KRAS mutant colorectal cancer (CRC) cells.
S. Ogbagabriel, Jian-Song Xie, Gloria Juan, C. Begley +2 more
20110 citations
Semantic Scholar

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