Helen Kotanides

Most-cited papers

1. Vascular Endothelial Growth Factor (VEGF)-driven Actin-based Motility Is Mediated by VEGFR2 and Requires Concerted Activation of Stress-activated Protein Kinase 2 (SAPK2/p38) and Geldanamycin-sensitive Phosphorylation of Focal Adhesion Kinase*

   S. Rousseau, François Houle, Helen Kotanides, L. Witte +3 more

   2000Journal of Biological Chemistry313 citations Open access

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2. Monoclonal antibodies targeting the VEGF receptor-2 (Flk1/KDR) as an anti-angiogenic therapeutic strategy

   L. Witte, D. Hicklin, Zhenping Zhu, B. Pytowski +3 more

   1998Cancer Metastasis Review284 citations

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3. Inhibition of vascular endothelial growth factor-induced receptor activation with anti-kinase insert domain-containing receptor single-chain antibodies from a phage display library.

   Zhen-Ping Zhu, P. Rockwell, Dan Lu, Helen Kotanides +4 more

   1998Cancer Research112 citations

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4. DEGA/AMIGO-2, a leucine-rich repeat family member, differentially expressed in human gastric adenocarcinoma: effects on ploidy, chromosomal stability, cell adhesion/migration and tumorigenicity

   K. Rabenau, Jennifer M O'Toole, R. Bassi, Helen Kotanides +3 more

   2004Oncogene78 citations Open access

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5. Cloning, genetic characterization, and chromosomal mapping of the mouse VDUP1 gene.

   D. Ludwig, Helen Kotanides, T. Le, Diana Chavkin +2 more

   2001Gene54 citations

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6. Inhibition of vascular endothelial growth factor induced mitogenesis of human endothelial cells by a chimeric anti-kinase insert domain-containing receptor antibody.

   Zhen-Ping Zhu, Dan Lu, Helen Kotanides, Angel Santiago +5 more

   1999Cancer Letters54 citations

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7. Bispecific Targeting of PD-1 and PD-L1 Enhances T-cell Activation and Antitumor Immunity

   Helen Kotanides, Yiwen Li, Maria Malabunga, C. Carpenito +24 more

   2020Cancer immunology research46 citations Open access

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8. Acquired antagonistic activity of a bispecific diabody directed against two different epitopes on vascular endothelial growth factor receptor 2.

   Dan Lu, Helen Kotanides, Xenia Jimenez, Qin-Wei Zhou +4 more

   1999JIM - Journal of Immunological Methods35 citations

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9. Characterization of 7A5: A Human CD137 (4-1BB) Receptor Binding Monoclonal Antibody with Differential Agonist Properties That Promotes Antitumor Immunity

   Helen Kotanides, R. M. Sattler, Maria B. Lebron, C. Carpenito +21 more

   2020Molecular Cancer Therapeutics15 citations Open access

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10. A human monoclonal antibody targeting the stem cell factor receptor (c-Kit) blocks tumor cell signaling and inhibits tumor growth

    Maria B. Lebron, L. Brennan, C. Damoci, M. Prewett +15 more

    2014Cancer Biology & Therapy13 citations Open access

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11. Abstract C159: A human monoclonal antibody targeting the stem cell factor receptor (c-Kit) blocks tumor cell signaling and inhibits tumor growth.

    Maria B. Lebron, L. Brennan, C. Damoci, M. Prewett +10 more

    20131 citations

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12. 707 Identification and characterization of DEGA, a novel leucine-rich repeat family member differentially expressed in human gastric adenocarcinoma: effects on cell cycle and tumorigenicity

    D. Pereira, K. Rabenau, Jennifer M O'Toole, K. Kobylarz +4 more

    20030 citations

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