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L. Elo · SciRah

Researcher profile · Semantic Scholar

L. Elo

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L. Elo — researcher profile on SciRah

h-index: 44
Works: 199
Citations: 8,689

Most-cited papers

Systematic evaluation of differential splicing tools for RNA-seq studies
A. Mehmood, A. Laiho, M. Venäläinen, A. McGlinchey +2 more
2019Briefings Bioinform.152 citations Open access
Semantic Scholar
Computational solutions for spatial transcriptomics
Iivari Kleino, Paulina Frolovaitė, T. Suomi, L. Elo
2022Computational and Structural Biotechnology Journal99 citations Open access
Semantic Scholar
Metagenomics analysis of gut microbiota in response to diet intervention and gestational diabetes in overweight and obese women: a randomised, double-blind, placebo-controlled clinical trial
K. Mokkala, Niklas Paulin, N. Houttu, E. Koivuniemi +6 more
2020Gut98 citations
Semantic Scholar
Computational strategies for single-cell multi-omics integration
Nigatu A. Adossa, Sofia Khan, K. Rytkönen, L. Elo
2021Computational and Structural Biotechnology Journal97 citations Open access
Semantic Scholar
Benchmarking methods for detecting differential states between conditions from multi-subject single-cell RNA-seq data
S. Junttila, Johannes Smolander, L. Elo
2022bioRxiv74 citations Open access
Semantic Scholar
Crowdsourcing digital health measures to predict Parkinson’s disease severity: the Parkinson’s Disease Digital Biomarker DREAM Challenge
S. Sieberts, J. Schaff, M. Duda, B. Pataki +39 more
2020bioRxiv63 citations Open access
Semantic Scholar
Secretin activates brown fat and induces satiation
Sanna Laurila, Lihua Sun, Minna Lahesmaa, K. Schnabl +17 more
2021Nature Metabolism59 citations
Semantic Scholar
Stable Iterative Variable Selection
Mehrad Mahmoudian, M. Venäläinen, R. Klén, L. Elo
2021Bioinform.55 citations Open access
Semantic Scholar
A carbohydrate-active enzyme (CAZy) profile links successful metabolic specialization of Prevotella to its abundance in gut microbiota
J. Aakko, Sami Pietilä, Raine K. Toivonen, A. Rokka +4 more
2020Scientific Reports55 citations Open access
Semantic Scholar
Integrative omics approaches provide biological and clinical insights: examples from mitochondrial diseases.
Sofia Khan, Gulayse Ince-Dunn, A. Suomalainen, L. Elo
2020Journal of Clinical Investigation48 citations Open access
Semantic Scholar
CIP2A interacts with TopBP1 and drives basal-like breast cancer tumorigenesis
A. Laine, S. Nagelli, Caroline C Farrington, Umar Butt +20 more
2021Cancer Research45 citations Open access
Semantic Scholar
Hypoxia-inducible factor (HIF)-prolyl hydroxylase 3 (PHD3) maintains high HIF2A mRNA levels in clear cell renal cell carcinoma
Petra Miikkulainen, H. Högel, Fatemeh Seyednasrollah, K. Rantanen +2 more
2019Journal of Biological Chemistry38 citations Open access
Semantic Scholar
Introducing untargeted data-independent acquisition for metaproteomics of complex microbial samples
Sami Pietilä, T. Suomi, L. Elo
2022ISME Communications36 citations Open access
Semantic Scholar
Risk factors for prosthetic joint infections following total hip arthroplasty based on 33,337 hips in the Finnish Arthroplasty Register from 2014 to 2018
Valtteri J. Panula, Kasperi J. Alakylä, M. Venäläinen, J. Haapakoski +7 more
2021Acta Orthopaedica36 citations Open access
Semantic Scholar
Compressive stress-mediated p38 activation required for ERα + phenotype in breast cancer
P. Munne, Lahja Martikainen, Iiris Räty, Kia Bertula +30 more
2021Nature Communications36 citations Open access
Semantic Scholar
Histone deacetylases 1 and 2 restrain CD4+ cytotoxic T lymphocyte differentiation
T. Preglej, Patricia Hamminger, M. Luu, Tanja Bulat +21 more
2020JCI Insight34 citations Open access
Semantic Scholar
MYO10-filopodia support basement membranes at pre-invasive tumor boundaries.
E. Peuhu, Guillaume Jacquemet, C. Scheele, Aleksi Isomursu +13 more
2022Developmental Cell32 citations Open access
Semantic Scholar
Evaluation of tools for identifying large copy number variations from ultra-low-coverage whole-genome sequencing data
Johannes Smolander, Sofia Khan, Kalaimathy Singaravelu, Leni Kauko +3 more
2021BMC Genomics31 citations Open access
Semantic Scholar
Protein synthesis is suppressed in sporadic and familial Parkinson’s Disease by LRRK2
Prasannakumar Deshpande, Dani Flinkman, Ye Hong, Elena Goltseva +7 more
2020bioRxiv29 citations Open access
Semantic Scholar
Early DNA methylation changes in children developing beta cell autoimmunity at a young age
I. Starskaia, E. Laajala, T. Grönroos, T. Härkönen +12 more
2022Diabetologia26 citations Open access
Semantic Scholar
Prediction of complication related death after radical cystectomy for bladder cancer with machine learning methodology
R. Klén, A. Salminen, Mehrad Mahmoudian, K. Syvänen +2 more
2019Scandinavian journal of urology26 citations Open access
Semantic Scholar
Preoperative Risk Prediction Models for Short-Term Revision and Death After Total Hip Arthroplasty
M. Venäläinen, Valtteri J. Panula, R. Klén, J. Haapakoski +7 more
2021JB & JS open access21 citations Open access
Semantic Scholar
MASTL promotes cell contractility and motility through kinase-independent signaling
M. E. Taskinen, Elisa Närvä, J. Conway, L. Hinojosa +8 more
2020Journal of Cell Biology21 citations Open access
Semantic Scholar
Polymorphism in interferon alpha/beta receptor contributes to glucocorticoid response and outcome of ARDS and COVID-19
J. Jalkanen, Sofia Khan, K. Elima, T. Huttunen +4 more
2023Critical Care19 citations Open access
Semantic Scholar
Tool evaluation for the detection of variably sized indels from next generation whole genome and targeted sequencing data
Ning Wang, V. Lysenkov, K. Orte, V. Kairisto +3 more
2022PLoS Comput. Biol.19 citations Open access
Semantic Scholar
PIM kinases regulate early human Th17 cell differentiation
T. Buchacher, Ankitha Shetty, S. A. Koskela, Johannes Smolander +10 more
2023Cell Reports18 citations Open access
Semantic Scholar
Risk factors for revision due to prosthetic joint infection following total knee arthroplasty based on 62,087 knees in the Finnish Arthroplasty Register from 2014 to 2020
H. Keemu, Kasperi J. Alakylä, R. Klén, Valtteri J. Panula +9 more
2023Acta Orthopaedica18 citations Open access
Semantic Scholar
Improved risk prediction of chemotherapy‐induced neutropenia—model development and validation with real‐world data
M. Venäläinen, E. Heervä, O. Hirvonen, Sohrab Saraei +6 more
2021Cancer Medicine18 citations Open access
Semantic Scholar
Adult-Onset Anti-Citrullinated Peptide Antibody-Negative Destructive Rheumatoid Arthritis Is Characterized by a Disease-Specific CD8+ T Lymphocyte Signature
T. Kelkka, P. Savola, Dipabarna Bhattacharya, Jani Huuhtanen +19 more
2020Frontiers in Immunology18 citations Open access
Semantic Scholar
Gene expression signature predicts rate of type 1 diabetes progression
T. Suomi, I. Starskaia, Ubaid Ullah Kalim, O. Rasool +138 more
2023EBioMedicine17 citations Open access
Semantic Scholar
SMG6 localizes to the chromatoid body and shapes the male germ cell transcriptome to drive spermatogenesis
Tiina Lehtiniemi, M. Bourgery, Lin Ma, A. Ahmedani +14 more
2022Nucleic Acids Research17 citations Open access
Semantic Scholar
Weight Loss Trajectories in Healthy Weight Coaching: Cohort Study
S. Kupila, M. Venäläinen, L. Suojanen, M. Rosengård-Bärlund +3 more
2022JMIR Formative Research16 citations Open access
Semantic Scholar
Computational deconvolution to estimate cell type-specific gene expression from bulk data
Maria K. Jaakkola, L. Elo
2021NAR Genomics and Bioinformatics16 citations
Semantic Scholar
Targeted serum proteomics of longitudinal samples from newly diagnosed youth with type 1 diabetes distinguishes markers of disease and C-peptide trajectory
R. Moulder, Tommi Välikangas, M. Hirvonen, T. Suomi +13 more
2023Diabetologia15 citations Open access
Semantic Scholar
A systematic comparison of FOSL1, FOSL2 and BATF-mediated transcriptional regulation during early human Th17 differentiation
A. Shetty, S. Tripathi, S. Junttila, T. Buchacher +9 more
2022Nucleic Acids Research14 citations Open access
Semantic Scholar
Discovery of a Novel CIP2A Variant (NOCIVA) with Clinical Relevance in Predicting TKI Resistance in Myeloid Leukemias
Eleonora Mäkelä, Karolina Pavic, Taru Varila, U. Salmenniemi +10 more
2021Clinical Cancer Research14 citations Open access
Semantic Scholar
CIP2A Constrains Th17 Differentiation by Modulating STAT3 Signaling
Mohd Moin Khan, Ubaid Ullah, M. H. Khan, Ling-Jia Kong +9 more
2020iScience14 citations Open access
Semantic Scholar
Distinct cellular immune responses in children en route to type 1 diabetes with different first-appearing autoantibodies
I. Starskaia, Milla Valta, Sami Pietilä, T. Suomi +12 more
2024Nature Communications13 citations Open access
Semantic Scholar
L1TD1 - a prognostic marker for colon cancer
D. Chakroborty, M. Emani, R. Klén, C. Böckelman +5 more
2019BMC Cancer13 citations Open access
Semantic Scholar
Cell-connectivity-guided trajectory inference from single-cell data
Johannes Smolander, S. Junttila, L. Elo
2023Bioinform.12 citations Open access
Semantic Scholar
Long Intergenic Noncoding RNA MIAT as a Regulator of Human Th17 Cell Differentiation
Mohd Moin Khan, M. H. Khan, Ubaid Ullah Kalim, Sofia Khan +6 more
2022Frontiers in Immunology12 citations Open access
Semantic Scholar
scShaper: an ensemble method for fast and accurate linear trajectory inference from single-cell RNA-seq data
Johannes Smolander, S. Junttila, M. Venäläinen, L. Elo
2021Bioinform.12 citations Open access
Semantic Scholar
Umbilical cord blood DNA methylation in children who later develop type 1 diabetes
E. Laajala, Ubaid Ullah Kalim, T. Grönroos, O. Rasool +20 more
2021Diabetologia12 citations Open access
Semantic Scholar
Dirichlet process mixture models for single-cell RNA-seq clustering
Nigatu A. Adossa, K. Rytkönen, L. Elo
2022Biology Open11 citations Open access
Semantic Scholar
COVID-19-specific transcriptomic signature detectable in blood across multiple cohorts
Tommi Välikangas, S. Junttila, K. Rytkönen, Anu Kukkonen-Macchi +2 more
2022Frontiers in Genetics11 citations Open access
Semantic Scholar
Persistent coxsackievirus B1 infection triggers extensive changes in the transcriptome of human pancreatic ductal cells
T. Buchacher, Anni Honkimaa, Tommi Välikangas, N. Lietzén +7 more
2021iScience11 citations Open access
Semantic Scholar
Complex Interplay Between MAZR and Runx3 Regulates the Generation of Cytotoxic T Lymphocyte and Memory T Cells
A. Gülich, R. Rîca, Caroline Tizian, C. Viczenczová +11 more
2021Frontiers in Immunology11 citations Open access
Semantic Scholar
Estimating cell type-specific differential expression using deconvolution
Maria K. Jaakkola, L. Elo
2021Briefings Bioinform.11 citations Open access
Semantic Scholar
A proximal enhancer regulates RORA expression during early human Th17 cell differentiation.
Ubaid Ullah Kalim, Rahul Biradar, S. Junttila, Mohd Moin Khan +10 more
2024Clinical Immunology10 citations Open access
Semantic Scholar
Histone H3K4me3 breadth in hypoxia reveals endometrial core functions and stress adaptation linked to endometriosis
K. Rytkönen, Thomas Faux, Mehrad Mahmoudian, T. Heinosalo +5 more
2022iScience10 citations Open access
Semantic Scholar

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A. Laiho×11
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M. Venäläinen×9
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