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Nisreen M. A. Okba · SciRah

Researcher profile · Semantic Scholar

Nisreen M. A. Okba

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Nisreen M. A. Okba — researcher profile on SciRah

h-index: 32
Works: 62
Citations: 9,735

Most-cited papers

Severe Acute Respiratory Syndrome Coronavirus 2−Specific Antibody Responses in Coronavirus Disease Patients
Nisreen M. A. Okba, M. Müller, Wen-Tao Li, Chunyan Wang +15 more
2020Emerging Infectious Diseases1,319 citations Open access
Semantic Scholar
Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability
P. Brouwer, Tom G. Caniels, K. van der Straten, Jonne L. Snitselaar +29 more
2020Science1,198 citations Open access
Semantic Scholar
A human monoclonal antibody blocking SARS-CoV-2 infection
Chunyan Wang, Wen-Tao Li, D. Drabek, Nisreen M. A. Okba +6 more
2020Nature Communications1,072 citations Open access
Semantic Scholar
Phenotype and kinetics of SARS-CoV-2-specific T cells in COVID-19 patients with acute respiratory distress syndrome
D. Weiskopf, K. Schmitz, M. Raadsen, A. Grifoni +10 more
2020Science immunology854 citations Open access
Semantic Scholar
Comparative pathogenesis of COVID-19, MERS, and SARS in a nonhuman primate model
B. Rockx, T. Kuiken, S. Herfst, T. Bestebroer +20 more
2020Science853 citations Open access
Semantic Scholar
Duration and key determinants of infectious virus shedding in hospitalized patients with coronavirus disease-2019 (COVID-19)
J. V. van Kampen, D. A. van de Vijver, P. Fraaij, B. Haagmans +21 more
2021Nature Communications656 citations Open access
Semantic Scholar
SARS-CoV-2 is transmitted via contact and via the air between ferrets
M. Richard, Adinda Kok, D. de Meulder, T. Bestebroer +8 more
2020Nature Communications437 citations Open access
Semantic Scholar
An evaluation of COVID-19 serological assays informs future diagnostics and exposure assessment
C. Geurtsvankessel, Nisreen M. A. Okba, Z. Iglói, S. Bogers +12 more
2020Nature Communications319 citations Open access
Semantic Scholar
Shedding of infectious virus in hospitalized patients with coronavirus disease-2019 (COVID-19): duration and key determinants
J. V. van Kampen, D. A. van de Vijver, P. Fraaij, B. Haagmans +21 more
2020medRxiv264 citations Open access
Semantic Scholar
An orthopoxvirus-based vaccine reduces virus excretion after MERS-CoV infection in dromedary camels
B. Haagmans, J. V. D. van den Brand, V. S. Raj, A. Volz +13 more
2016Science248 citations Open access
Semantic Scholar
SARS-CoV-2 specific antibody responses in COVID-19 patients
Nisreen M. A. Okba, M. Muller, Wen-Tao Li, Chunyan Wang +15 more
2020medRxiv225 citations Open access
Semantic Scholar
Convalescent Plasma for COVID-19. A randomized clinical trial
Arvind Gharbharan, C. Jordans, Corine H. Geurts van Kessel, J. den Hollander +24 more
2020medRxiv220 citations Open access
Semantic Scholar
A conserved immunogenic and vulnerable site on the coronavirus spike protein delineated by cross-reactive monoclonal antibodies
Chunyan Wang, Rien van Haperen, J. Gutiérrez-Álvarez, Wen-Tao Li +14 more
2021Nature Communications185 citations Open access
Semantic Scholar
Two-component spike nanoparticle vaccine protects macaques from SARS-CoV-2 infection
P. Brouwer, Mitch Brinkkemper, P. Maisonnasse, N. Dereuddre-Bosquet +43 more
2020bioRxiv182 citations Open access
Semantic Scholar
Effects of potent neutralizing antibodies from convalescent plasma in patients hospitalized for severe SARS-CoV-2 infection
A. Gharbharan, C. Jordans, C. Geurtsvankessel, J. den Hollander +28 more
2020Nature Communications150 citations Open access
Semantic Scholar
Safety and immunogenicity of a modified vaccinia virus Ankara vector vaccine candidate for Middle East respiratory syndrome: an open-label, phase 1 trial
T. Koch, C. Dahlke, A. Fathi, A. Kupke +21 more
2020Lancet. Infectious Diseases (Print)132 citations Open access
Semantic Scholar
Susceptibility of rabbits to SARS-CoV-2
A. Mykytyn, M. Lamers, Nisreen M. A. Okba, Tim I. Breugem +9 more
2020bioRxiv131 citations Open access
Semantic Scholar
Towards a solution to MERS: protective human monoclonal antibodies targeting different domains and functions of the MERS-coronavirus spike glycoprotein
Ivy Widjaja, Chunyan Wang, Rien van Haperen, J. Gutiérrez-Álvarez +11 more
2019Emerging Microbes and Infections118 citations Open access
Semantic Scholar
Immunogenicity and efficacy of the COVID-19 candidate vector vaccine MVA-SARS-2-S in preclinical vaccination
A. Tscherne, J. Schwarz, Cornelius Rohde, A. Kupke +25 more
2021Proceedings of the National Academy of Sciences of the United States of America92 citations Open access
Semantic Scholar
Phenotype of SARS-CoV-2-specific T-cells in COVID-19 patients with acute respiratory distress syndrome
D. Weiskopf, K. Schmitz, M. Raadsen, A. Grifoni +10 more
2020medRxiv88 citations Open access
Semantic Scholar
Sensitive and Specific Detection of Low-Level Antibody Responses in Mild Middle East Respiratory Syndrome Coronavirus Infections
Nisreen M. A. Okba, V. S. Raj, Ivy Widjaja, C. Geurtsvankessel +11 more
2019Emerging Infectious Diseases81 citations Open access
Semantic Scholar
Chimeric camel/human heavy-chain antibodies protect against MERS-CoV infection
V. Stalin Raj, Nisreen M. A. Okba, J. Gutiérrez-Álvarez, D. Drabek +13 more
2018Science Advances80 citations Open access
Semantic Scholar
Middle East respiratory syndrome coronavirus vaccines: current status and novel approaches
Nisreen M. A. Okba, V. S. Raj, B. Haagmans
2017Current Opinion in Virology60 citations Open access
Semantic Scholar
Towards the next phase: evaluation of serological assays for diagnostics and exposure assessment.
Corine H. Geurts van Kessel, Nisreen M. A. Okba, Zsofia Igloi, C. Embregts +9 more
2020medRxiv59 citations Open access
Semantic Scholar
MERS-coronavirus: From discovery to intervention
W. Widagdo, Nisreen M. A. Okba, V. Stalin Raj, B. Haagmans
2016One Health56 citations Open access
Semantic Scholar
Publisher Correction: A human monoclonal antibody blocking SARS-CoV-2 infection
Chunyan Wang, Wen-Tao Li, D. Drabek, Nisreen M. A. Okba +6 more
2020Nature Communications53 citations Open access
Semantic Scholar
Comparative Pathogenesis Of COVID-19, MERS And SARS In A Non-Human Primate Model
B. Rockx, T. Kuiken, S. Herfst, T. Bestebroer +17 more
2020bioRxiv51 citations Open access
Semantic Scholar
SARS-CoV-2 neutralizing human antibodies protect against lower respiratory tract disease in a hamster model
B. Haagmans, D. Noack, Nisreen M. A. Okba, Wen-Tao Li +18 more
2020bioRxiv45 citations Open access
Semantic Scholar
Middle East respiratory syndrome coronavirus specific antibodies in naturally exposed Israeli llamas, alpacas and camels
D. David, Ditza Rotenberg, E. Khinich, Oran Erster +7 more
2018One Health42 citations Open access
Semantic Scholar
Seasonal coronavirus–specific B cells with limited SARS-CoV-2 cross-reactivity dominate the IgG response in severe COVID-19
Muriel Aguilar-Bretones, M. Raadsen, E. de Bruin, Nisreen M. A. Okba +10 more
202138 citations
Semantic Scholar
Species-Specific Colocalization of Middle East Respiratory Syndrome Coronavirus Attachment and Entry Receptors
W. Widagdo, Nisreen M. A. Okba, Wen-Tao Li, A. D. de Jong +5 more
2019Journal of Virology38 citations Open access
Semantic Scholar
Particulate multivalent presentation of the receptor binding domain induces protective immune responses against MERS-CoV
Nisreen M. A. Okba, Ivy Widjaja, Brenda van Dieren, A. Aebischer +9 more
2020Emerging Microbes and Infections35 citations Open access
Semantic Scholar
Modulation of lipid nanoparticle-formulated plasmid DNA drives innate immune activation promoting adaptive immunity
Nicholas J. Tursi, Sachchidanand Tiwari, N. Bedanova, Toshitha Kannan +26 more
2025Cell Reports Medicine33 citations Open access
Semantic Scholar
A single subcutaneous or intranasal immunization with adenovirus‐based SARS‐CoV‐2 vaccine induces robust humoral and cellular immune responses in mice
Eun Kim, Florian J. Weisel, Stephen C. Balmert, M. S. Khan +16 more
2021European Journal of Immunology32 citations Open access
Semantic Scholar
Blocking transmission of Middle East respiratory syndrome coronavirus (MERS-CoV) in llamas by vaccination with a recombinant spike protein
J. Rodón, Nisreen M. A. Okba, Nigeer Te, Brenda van Dieren +5 more
2019Emerging Microbes and Infections31 citations Open access
Semantic Scholar
Severe COVID-19 patients display a back boost of seasonal coronavirus-specific antibodies
B. Westerhuis, Muriel Aguilar-Bretones, M. Raadsen, E. de Bruin +10 more
2020medRxiv30 citations Open access
Semantic Scholar
MERS-CoV in Camels but Not Camel Handlers, Sudan, 2015 and 2017
E. Farag, R. Sikkema, A. Mohamedani, E. de Bruin +17 more
2019Emerging Infectious Diseases26 citations Open access
Semantic Scholar
Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Seropositive Camel Handlers in Kenya
A. Kiyong'a, E. Cook, Nisreen M. A. Okba, V. Kivali +3 more
2020Viruses25 citations Open access
Semantic Scholar
Zika Virus Infection Induces Elevation of Tissue Factor Production and Apoptosis on Human Umbilical Vein Endothelial Cells
Fatih Anfasa, M. Goeijenbier, W. Widagdo, J. Siegers +7 more
2019Frontiers in Microbiology25 citations Open access
Semantic Scholar
Serologic Detection of Middle East Respiratory Syndrome Coronavirus Functional Antibodies
Nisreen M. A. Okba, Ivy Widjaja, Wen-Tao Li, C. Geurtsvankessel +8 more
2020Emerging Infectious Diseases23 citations Open access
Semantic Scholar
Seasonal coronavirus-specific B-cells with limited SARS-CoV-2 cross-reactivity dominate the IgG response in severe COVID-19 patients.
Muriel Aguilar-Bretones, B. Westerhuis, M. Raadsen, E. de Bruin +14 more
2021Journal of Clinical Investigation19 citations Open access
Semantic Scholar
Increased neutralization and IgG epitope identification after MVA-MERS-S booster vaccination against Middle East respiratory syndrome
A. Fathi, C. Dahlke, Verena Krähling, A. Kupke +23 more
2022Nature Communications16 citations Open access
Semantic Scholar
Homologous and heterologous antibodies to coronavirus 229E, NL63, OC43, HKU1, SARS, MERS and SARS-CoV-2 antigens in an age stratified cross-sectional serosurvey in a large tertiary hospital in The Netherlands
B. Westerhuis, E. de Bruin, F. Chandler, C. Ramakers +9 more
2020medRxiv16 citations Open access
Semantic Scholar
Characterization of non-neutralizing human monoclonal antibodies that target the M1 and NP of influenza A viruses
W. Rijnink, D. Stadlbauer, E. Puente-Massaguer, Nisreen M. A. Okba +7 more
2023Journal of Virology15 citations Open access
Semantic Scholar
Experimental and field investigations of exposure, replication and transmission of SARS-CoV-2 in pigs in the Netherlands
R. Sikkema, T. Tobias, N. Oreshkova, E. de Bruin +17 more
2021Emerging Microbes and Infections13 citations Open access
Semantic Scholar
Lack of Middle East Respiratory Syndrome Coronavirus Transmission in Rabbits
W. Widagdo, Nisreen M. A. Okba, M. Richard, D. de Meulder +10 more
2019Viruses12 citations Open access
Semantic Scholar
Identification of a seasonal influenza vaccine-induced broadly protective neuraminidase antibody.
Anders Madsen, Nisreen M. A. Okba, T. Pholcharee, Hanover C Matz +11 more
2025Journal of Experimental Medicine10 citations Open access
Semantic Scholar
Broadly protective bispecific antibodies that simultaneously target influenza virus hemagglutinin and neuraminidase
Kevin E. Ramos, Nisreen M. A. Okba, Jessica Tan, Pooja D. Bandawane +9 more
2024mBio9 citations Open access
Semantic Scholar
Extended Viral Shedding of MERS-CoV Clade B Virus in Llamas Compared with African Clade C Strain
J. Rodón, A. Mykytyn, Nigeer Te, Nisreen M. A. Okba +10 more
2023Emerging Infectious Diseases8 citations Open access
Semantic Scholar
Isolation of cross-reactive monoclonal antibodies against divergent human coronaviruses that delineate a conserved and vulnerable site on the spike protein
Chunyan Wang, Rien van Haperen, J. Gutiérrez-Álvarez, Wen-Tao Li +14 more
2020bioRxiv8 citations Open access
Semantic Scholar

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