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B. Gran · SciRah

Researcher profile · Semantic Scholar

B. Gran

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B. Gran — researcher profile on SciRah

h-index: 48
Works: 155
Citations: 9,487

Most-cited papers

Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS)
C. Constantinescu, N. Farooqi, Kate M. O'Brien, B. Gran
2011British Journal of Pharmacology1,404 citations Open access
Semantic Scholar
IDO upregulates regulatory T cells via tryptophan catabolite and suppresses encephalitogenic T cell responses in experimental autoimmune encephalomyelitis
Ya-ping Yan, Guang-Xian Zhang, B. Gran, F. Fallarino +5 more
2010Journal of Immunology359 citations Open access
Semantic Scholar
Fatigue in multiple sclerosis - a brief review.
Isuru Induruwa, C. Constantinescu, B. Gran
2012Journal of Neurological Sciences249 citations
Semantic Scholar
EAE: imperfect but useful models of multiple sclerosis.
B. '. 't Hart, B. Gran, Robert Weissert
2011Trends in Molecular Medicine180 citations
Semantic Scholar
TLR2 Stimulation Drives Human Naive and Effector Regulatory T Cells into a Th17-Like Phenotype with Reduced Suppressive Function
M. Nyirenda, L. Sanvito, P. Darlington, Kate M. O'Brien +4 more
2011Journal of Immunology169 citations Open access
Semantic Scholar
CpG Type A Induction of an Early Protective Environment in Experimental Multiple Sclerosis
J. Crooks, M. Gargaro, C. Vacca, C. Volpi +9 more
2017Mediators of Inflammation168 citations Open access
Semantic Scholar
Multiple sclerosis-associated IL2RA polymorphism controls GM-CSF production in human TH cells
F. Hartmann, M. Khademi, J. Aram, S. Ammann +7 more
2014Nature Communications164 citations Open access
Semantic Scholar
The association between human endogenous retroviruses and multiple sclerosis: A systematic review and meta-analysis
E. Morandi, R. Tanasescu, R. Tarlinton, C. Constantinescu +3 more
2017PLoS ONE95 citations Open access
Semantic Scholar
CNS-specific therapy for ongoing EAE by silencing IL-17 pathway in astrocytes.
Ya-ping Yan, Xiaoli Ding, Ke Li, B. Ciric +5 more
2012Molecular Therapy89 citations Open access
Semantic Scholar
Therapeutic effect of baicalin on experimental autoimmune encephalomyelitis is mediated by SOCS3 regulatory pathway
Y. Zhang, Xing Li, B. Ciric, Cun-Gen Ma +3 more
2015Scientific Reports86 citations Open access
Semantic Scholar
TLR2 Stimulation Regulates the Balance between Regulatory T Cell and Th17 Function: A Novel Mechanism of Reduced Regulatory T Cell Function in Multiple Sclerosis
M. Nyirenda, E. Morandi, U. Vinkemeier, D. Constantin-Teodosiu +9 more
2015Journal of Immunology76 citations Open access
Semantic Scholar
Interaction between cytokines, cannabinoids and the nervous system.
L. Jean-Gilles, B. Gran, C. Constantinescu
2010Immunobiology74 citations
Semantic Scholar
Abnormal effector and regulatory T cell subsets in paediatric-onset multiple sclerosis
Ina Mexhitaj, M. Nyirenda, Rui Li, Julia O'Mahony +12 more
2019Brain : a journal of neurology73 citations Open access
Semantic Scholar
Are current disease‐modifying therapeutics in multiple sclerosis justified on the basis of studies in experimental autoimmune encephalomyelitis?
N. Farooqi, B. Gran, C. Constantinescu
2010Journal of Neurochemistry69 citations Open access
Semantic Scholar
Hookworm Treatment for Relapsing Multiple Sclerosis: A Randomized Double-Blinded Placebo-Controlled Trial.
R. Tanasescu, C. Tench, C. Constantinescu, G. Telford +11 more
2020JAMA Neurology63 citations Open access
Semantic Scholar
The primate autoimmune encephalomyelitis model; a bridge between mouse and man
B. '. 't Hart, Y. van Kooyk, J. Geurts, B. Gran
2015Annals of Clinical and Translational Neurology60 citations Open access
Semantic Scholar
Effects of cigarette smoke on immunity, neuroinflammation and multiple sclerosis.
Mohammed Alrouji, A. Manouchehrinia, B. Gran, C. Constantinescu
2019Journal of Neuroimmunology56 citations
Semantic Scholar
Helicobacter pylori infection reduces disease severity in an experimental model of multiple sclerosis
K. Cook, J. Crooks, Khiyam Hussain, Kate M. O'Brien +5 more
2015Frontiers in Microbiology56 citations Open access
Semantic Scholar
Increased levels of interleukins 2 and 17 in the cerebrospinal fluid of patients with idiopathic intracranial hypertension.
L. Edwards, B. Sharrack, A. Ismail, C. Tench +5 more
2013American Journal of Clinical and Experimental Immunology56 citations
Semantic Scholar
Lymphocryptovirus Infection of Nonhuman Primate B Cells Converts Destructive into Productive Processing of the Pathogenic CD8 T Cell Epitope in Myelin Oligodendrocyte Glycoprotein
S. A. Jagessar, I. Holtman, S. Hofman, E. Morandi +7 more
2016Journal of Immunology51 citations Open access
Semantic Scholar
EBV Infection and Multiple Sclerosis: Lessons from a Marmoset Model.
Bert A. ’tHart, Y. Kap, E. Morandi, J. Laman +1 more
2016Trends in Molecular Medicine48 citations Open access
Semantic Scholar
Intranasal Delivery of Neural Stem Cells: A CNS-specific, Non-invasive Cell-based Therapy for Experimental Autoimmune Encephalomyelitis
Shuai Wu, Ke Li, Ya-ping Yan, B. Gran +5 more
2013Journal of Clinical & Cellular Immunology46 citations Open access
Semantic Scholar
The Soluble Form of Toll-Like Receptor 2 Is Elevated in Serum of Multiple Sclerosis Patients: A Novel Potential Disease Biomarker
Md. Jakir Hossain, E. Morandi, R. Tanasescu, N. Frakich +5 more
2018Frontiers in Immunology44 citations Open access
Semantic Scholar
The Potential for EBV Vaccines to Prevent Multiple Sclerosis
P. Maple, A. Ascherio, J. Cohen, G. Cutter +4 more
2022Frontiers in Neurology41 citations Open access
Semantic Scholar
Urinary tract infections in multiple sclerosis: under-diagnosed and under-treated? A clinical audit at a large University Hospital.
A. Mahadeva, R. Tanasescu, B. Gran
2014American Journal of Clinical and Experimental Immunology41 citations
Semantic Scholar
Neural Stem Cells Engineered to Express Three Therapeutic Factors Mediate Recovery from Chronic Stage CNS Autoimmunity
Xing Li, Y. Zhang, Ya-ping Yan, B. Ciric +5 more
2016Molecular Therapy40 citations Open access
Semantic Scholar
Effect of Fingolimod on Neural Stem Cells: A Novel Mechanism and Broadened Application for Neural Repair.
Yuan Zhang, Xing Li, B. Ciric, Cun-Gen Ma +3 more
2017Molecular Therapy39 citations Open access
Semantic Scholar
Multiple Sclerosis between Genetics and Infections: Human Endogenous Retroviruses in Monocytes and Macrophages
E. Morandi, R. Tarlinton, B. Gran
2015Frontiers in Immunology39 citations Open access
Semantic Scholar
Accelerated and enhanced effect of CCR5-transduced bone marrow neural stem cells on autoimmune encephalomyelitis
Jing-Xian Yang, Ya-ping Yan, Cun-Gen Ma, Ting-Guo Kang +9 more
2012Acta Neuropathologica39 citations Open access
Semantic Scholar
The essential role of t cells in multiple sclerosis: A reappraisal
C. Constantinescu, B. Gran
2014Biomedical Journal37 citations Open access
Semantic Scholar
A different response to Cytomegalovirus (CMV) and Epstein-Barr virus (EBV) infection in UK people with multiple sclerosis (PwMS) compared to controls.
P. Maple, R. Tanasescu, B. Gran, C. Constantinescu
2020Journal of Infection36 citations
Semantic Scholar
Interferon regulatory factor (IRF) 3 is critical for the development of experimental autoimmune encephalomyelitis
Denise C. Fitzgerald, Kate M. O'Brien, A. Young, Zoe Fonseca-Kelly +2 more
2014Journal of Neuroinflammation36 citations Open access
Semantic Scholar
Do Antiretroviral Drugs Protect From Multiple Sclerosis by Inhibiting Expression of MS-Associated Retrovirus?
E. Morandi, R. Tanasescu, R. Tarlinton, D. Constantin-Teodosiu +1 more
2019Frontiers in Immunology35 citations Open access
Semantic Scholar
Innate immune regulation of autoimmunity in multiple sclerosis: Focus on the role of Toll-like receptor 2.
Md. Jakir Hossain, R. Tanasescu, B. Gran
2017Journal of Neuroimmunology35 citations
Semantic Scholar
Identification of the Synthetic Cannabinoid R(+)WIN55,212-2 as a Novel Regulator of IFN Regulatory Factor 3 Activation and IFN-β Expression
Eric J. Downer, E. Clifford, B. Gran, H. Nel +2 more
2011Journal of Biological Chemistry35 citations Open access
Semantic Scholar
Discrepant Effects of Human Interferon-gamma on Clinical and Immunological Disease Parameters in a Novel Marmoset Model for Multiple Sclerosis
S. A. Jagessar, B. Gran, N. Heijmans, J. Bauer +3 more
2011Journal of Neuroimmune Pharmacology34 citations Open access
Semantic Scholar
The TLR7 agonist, imiquimod, increases IFN-beta production and reduces the severity of experimental autoimmune encephalomyelitis.
Kate M. O'Brien, Denise C. Fitzgerald, A. Rostami, B. Gran
2010Journal of Neuroimmunology33 citations
Semantic Scholar
Reciprocal Regulation of Substance P and IL-12/IL-23 and the Associated Cytokines, IFNγ/IL-17: A Perspective on the Relevance of This Interaction to Multiple Sclerosis
J. Vilisaar, K. Kawabe, M. Braitch, J. Aram +8 more
2015Journal of Neuroimmune Pharmacology32 citations Open access
Semantic Scholar
T-cell based immunotherapy in experimental autoimmune encephalomyelitis and multiple sclerosis
Kate M. O'Brien, B. Gran, A. Rostami
2010Immunotherapy30 citations Open access
Semantic Scholar
A GpC-Rich Oligonucleotide Acts on Plasmacytoid Dendritic Cells To Promote Immune Suppression
C. Volpi, F. Fallarino, R. Bianchi, C. Orabona +7 more
2012Journal of Immunology26 citations Open access
Semantic Scholar
Multiple sclerosis: Autoimmune associations in multiple sclerosis
C. Constantinescu, B. Gran
2010Nature Reviews Neurology24 citations
Semantic Scholar
Reduced Myelin Signal in Normal-appearing White Matter in Neuromyelitis Optica Measured by 7T Magnetic Resonance Imaging
I-Jun Chou, R. Tanasescu, Olivier E. Mougin, P. Gowland +7 more
2019Scientific Reports22 citations Open access
Semantic Scholar
Human endogenous retroviruses and multiple sclerosis: Causation, association, or after-effect?
E. Morandi, R. Tarlinton, R. Tanasescu, B. Gran
2017Multiple Sclerosis17 citations Open access
Semantic Scholar
Innate Immune Responses in the CNS: Role of Toll-Like Receptors, Mechanisms, and Therapeutic Opportunities in Multiple Sclerosis
Giulio Podda, M. Nyirenda, J. Crooks, B. Gran
2013Journal of Neuroimmune Pharmacology17 citations
Semantic Scholar
CCN3 is dynamically regulated by treatment and disease state in multiple sclerosis
M. Naughton, Jill Moffat, G. Eleftheriadis, Nira de la Vega Gallardo +15 more
2020Journal of Neuroinflammation14 citations Open access
Semantic Scholar
PAF-R on activated T cells: Role in the IL-23/Th17 pathway and relevance to multiple sclerosis
A. Midgley, D. Barakat, M. Braitch, C. Nichols +7 more
2020Immunobiology13 citations Open access
Semantic Scholar
Delineating the Role of Toll-Like Receptors in the Neuro-inflammation Model EAE.
F. Fallarino, M. Gargaro, Giada Mondanell, Eric J. Downer +2 more
2016Methods in molecular biology12 citations
Semantic Scholar
Differential Expression of HERV-W in Peripheral Blood in Multiple Sclerosis and Healthy Patients in Two Different Ethnic Groups
R. Tarlinton, Belinda Wang, E. Morandi, B. Gran +4 more
2020Frontiers in Pharmacology11 citations Open access
Semantic Scholar
Subcutaneous cladribine to treat multiple sclerosis: experience in 208 patients
K. Allen-Philbey, S. De Trane, Z. Mao, C. Álvarez-González +34 more
2021Therapeutic Advances in Neurological Disorders10 citations Open access
Semantic Scholar
Increased IL-2 and Reduced TGF-β Upon T-Cell Stimulation are Associated with GM-CSF Upregulation in Multiple Immune Cell Types in Multiple Sclerosis
J. Aram, N. Frakich, E. Morandi, Mohammad Alrouji +7 more
2020Biomedicines9 citations Open access
Semantic Scholar

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R. Tanasescu×12
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Guang-Xian Zhang

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Kate M. O'Brien×6

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