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G. Hardisty · SciRah

Researcher profile · Semantic Scholar

G. Hardisty

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G. Hardisty — researcher profile on SciRah

h-index: 11
Works: 35
Citations: 828

Most-cited papers

Neutrophil Extracellular Traps in Inflammatory Bowel Disease: Pathogenic Mechanisms and Clinical Translation
B. Drury, G. Hardisty, R. Gray, G. Ho
2021Cellular and Molecular Gastroenterology and Hepatology198 citations Open access
Semantic Scholar
Delayed Neutrophil Apoptosis Enhances NET Formation in Cystic Fibrosis
R. Gray, G. Hardisty, K. Regan, Maeve P. Smith +18 more
2017Thorax174 citations Open access
Semantic Scholar
The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation
Danielle Minns, K. Smith, Virginia Alessandrini, G. Hardisty +5 more
2020Nature Communications139 citations Open access
Semantic Scholar
High Purity Isolation of Low Density Neutrophils Casts Doubt on Their Exceptionality in Health and Disease
G. Hardisty, Frances Llanwarne, Danielle Minns, J. Gillan +3 more
2021Frontiers in Immunology53 citations Open access
Semantic Scholar
Randomised controlled trial of intravenous nafamostat mesylate in COVID pneumonitis: Phase 1b/2a experimental study to investigate safety, Pharmacokinetics and Pharmacodynamics
T. Quinn, E. Gaughan, A. Bruce, J. Antonelli +45 more
2022EBioMedicine46 citations Open access
Semantic Scholar
The Outcome of Neutrophil-T Cell Contact Differs Depending on Activation Status of Both Cell Types
Danielle Minns, K. Smith, G. Hardisty, A. G. Rossi +1 more
2020bioRxiv46 citations Open access
Semantic Scholar
Role of the B Allele of Influenza A Virus Segment 8 in Setting Mammalian Host Range and Pathogenicity
Matthew L. Turnbull, H. Wise, M. Q. Nicol, Nikki Smith +16 more
2016Journal of Virology32 citations Open access
Semantic Scholar
An Inhaled Galectin-3 Inhibitor in COVID-19 Pneumonitis: A Phase Ib/IIa Randomized Controlled Clinical Trial (DEFINE)
E. Gaughan, T. Quinn, Andrew Mills, A. Bruce +35 more
2022American Journal of Respiratory and Critical Care Medicine30 citations Open access
Semantic Scholar
Human cystic fibrosis monocyte derived macrophages display no defect in acidification of phagolysosomes when measured by optical nanosensors.
S. Law, Samuel J Stanfield, G. Hardisty, I. Dransfield +2 more
2020Journal of Cystic Fibrosis27 citations Open access
Semantic Scholar
CAGE sequencing reveals CFTR-dependent dysregulation of type I IFN signaling in activated cystic fibrosis macrophages
J. Gillan, Mithil Chokshi, G. Hardisty, S. Clohisey Hendry +10 more
2023Science Advances15 citations Open access
Semantic Scholar
Concurrent Infection With the Filarial Helminth Litomosoides sigmodontis Attenuates or Worsens Influenza A Virus Pathogenesis in a Stage-Dependent Manner
G. Hardisty, J. Knipper, A. Fulton, J. Hopkins +2 more
2022Frontiers in Immunology12 citations Open access
Semantic Scholar
Neutrophil-dependent Mitochondrial DNA Release Associated With Extracellular Trap Formation in Inflammatory Bowel Disease
B. Drury, C. Chuah, Rebecca Hall, G. Hardisty +2 more
2023Gastro Hep Advances9 citations Open access
Semantic Scholar
Ivacaftor modifies cystic fibrosis neutrophil phenotype in subjects with R117H residual function CFTR mutations
G. Hardisty, S. Law, S. Carter, B. Grogan +3 more
2020European Respiratory Journal9 citations Open access
Semantic Scholar
Neutrophil extracellular traps are associated with airways inflammation and increased severity of lung disease in cystic fibrosis
S. Law, G. Hardisty, J. Gillan, Nicola J Robinson +4 more
2024ERJ Open Research8 citations Open access
Semantic Scholar
SERS Microsensors for the Study of pH Regulation in Cystic Fibrosis Patient-Derived Airway Cultures
William H. Skinner, Nicola J Robinson, G. Hardisty, Robert D. Gray +1 more
2024ACS Sensors8 citations Open access
Semantic Scholar
SERS microsensors for pH measurements in the lumen and ECM of stem cell derived human airway organoids.
C. Campbell, William H. Skinner, Nicola J Robinson, G. Hardisty +4 more
2023Chemical Communications7 citations Open access
Semantic Scholar
Ultra-pure isolation of low density neutrophils casts doubt on their exceptionality in health and disease
G. Hardisty, Frances Llanwarne, Danielle Minns, J. Gillan +3 more
2020bioRxiv6 citations Open access
Semantic Scholar
Macrophages from gut-corrected CF mice express human CFTR and lack a pro-inflammatory phenotype
J. Gillan, G. Hardisty, D. Davidson, R. Gray
2021Journal of Cystic Fibrosis4 citations Open access
Semantic Scholar
Latent gammaherpesvirus infection enhances type I IFN response and reduces virus spread in an influenza A virus co-infection model.
G. Hardisty, M. Q. Nicol, Darren J Shaw, I. Bennet +6 more
2024Journal of General Virology1 citations Open access
Semantic Scholar
T regulatory cells promote bile duct regeneration through modulating ductular reaction in a model of cholestatic liver injury
Naruhiro Kimura, G. Hardisty, A. Tsuchiya, S. Terai +2 more
2022Journal of Hepatology1 citations
Semantic Scholar
P240 Elexacaftor/tezacaftor/ivacaftor treatment improves cystic fibrosis quality of life over multiple domains
N. Robinson, A. Gordon, L. Hunt, G. Hardisty +1 more
2022Journal of Cystic Fibrosis1 citations Open access
Semantic Scholar
P218 CFTR modulators in the real world: an observational study of patient response to tezacaftor/ivacaftor therapy
N. Robinson, C. McMullan, A. Berwick, J. Robertson +4 more
20201 citations Open access
Semantic Scholar
WS08-1 Calprotectin: the cystic fibrosis antigen regulates neutrophil migration during experimental lung inflammation and is a novel therapeutic target in cystic fibrosis
G. Hardisty, S. Law, J. Gillan, E. Findlay +3 more
2019Journal of Cystic Fibrosis1 citations Open access
Semantic Scholar
Pharmacological correction of CFTR improves systemic inflammation and lung disease in Cystic Fibrosis but does not correct a basic defect in lung repair
N. Robinson, G. Hardisty, J. Gillan, R. C. Quisilema +4 more
2026medRxiv0 citations Open access
Semantic Scholar
P162 Elexacaftor/tezacaftor/ivacaftor significantly improves thoracic radiological outcomes in cystic fibrosis
N. Robinson, G. Hardisty, A. Baird, R. Gray
2023Journal of Cystic Fibrosis0 citations Open access
Semantic Scholar
443 Elexacaftor/tezacaftor/ivacaftor treatment promotes inflammation resolution in people with cystic fibrosis
N. Robinson, G. Hardisty, J. Gillan, R. Gray
2022Journal of Cystic Fibrosis0 citations Open access
Semantic Scholar
ePS5.08 The effects on systemic inflammation of elexacaftor/tezacaftor/ivacaftor
N. Robinson, G. Hardisty, R. Gray
2022Journal of Cystic Fibrosis0 citations Open access
Semantic Scholar
WS17.05 Elexacaftor/tezacaftor/ivacaftor (ETI) treatment in people with cystic fibrosis (pwCF) impacts airway progenitor cell function
N. Robinson, G. Hardisty, R. Gray
2022Journal of Cystic Fibrosis0 citations Open access
Semantic Scholar
TITLE: Randomised Controlled Trial of Intravenous Nafamostat Mesylate in COVID pneumonitis: Phase 1b/2a Experimental Study to Investigate Safety, Pharmacokinetics and Pharmacodynamics
T. Quinn, E. Gaughan, A. Bruce, J. Antonelli +45 more
2021medRxiv0 citations Open access
Semantic Scholar
350: Elexacaftor-tezacaftor-ivacaftor treatment fundamentally changes the inflammatory landscape in people with CF
G. Hardisty, N. Robinson, J. Gillan, L. Hunt +1 more
2021Journal of Cystic Fibrosis0 citations Open access
Semantic Scholar
349: Tezacaftor/ivacaftor improves clinical outcomes but has only modest effects on inflammation in CF
N. Robinson, G. Hardisty, J. Gillan, R. Gray
2021Journal of Cystic Fibrosis0 citations Open access
Semantic Scholar
ePS3.03 Probing the central role of macrophages in cystic fibrosis inflammation
J. Gillan, G. Hardisty, N. Robinson, R. Gray
20200 citations Open access
Semantic Scholar
P221 Neutrophil extracellular traps are elevated in cystic fibrosis sputum and associated with neutrophilic inflammation and lung function decline
S. Law, G. Hardisty, I. Dransfield, R. Gray
2019Journal of Cystic Fibrosis0 citations Open access
Semantic Scholar
74 Ivacaftor treatment activates circulating neutrophils in R117H patients: potential for a CFTR independent mechanism
G. Hardisty, S. Law, S. Carter, B. Grogan +3 more
20170 citations Open access
Semantic Scholar
Effect of on-going and persistent infection on acute respiratory infection with influenza A
G. Hardisty
20160 citations
Semantic Scholar

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