Researcher profile · Semantic Scholar

Karen D. Simpson

h-index: 12
Works: 23
Citations: 1,229

Most-cited papers

The nuclear receptor REV-ERBα mediates circadian regulation of innate immunity through selective regulation of inflammatory cytokines
J. Gibbs, J. Blaikley, Stephen Beesley, L. Matthews +7 more
2011Proceedings of the National Academy of Sciences of the United States of America656 citations Open access
Semantic Scholar
Obesity and disease severity magnify disturbed microbiome-immune interactions in asthma patients
D. Michalovich, Noelia Rodriguez-Perez, S. Smolińska, M. Pirożyński +24 more
2019Nature Communications201 citations Open access
Semantic Scholar
Neuronal Markers in Allergic Rhinitis: Expression and Correlation With Sensory Testing
S. O'Hanlon, P. Facer, Karen D. Simpson, G. Sandhu +2 more
2007The Laryngoscope58 citations
Semantic Scholar
The MIF Antagonist ISO-1 Attenuates Corticosteroid-Insensitive Inflammation and Airways Hyperresponsiveness in an Ozone-Induced Model of COPD
Kirsty E. Russell, K. Chung, Colin J Clarke, A. Durham +10 more
2016PLoS ONE56 citations Open access
Semantic Scholar
Altered fatty acid metabolism and reduced stearoyl‐coenzyme a desaturase activity in asthma
Noelia Rodriguez-Perez, Elisa Schiavi, R. Frei, Ruth Ferstl +14 more
2017Allergy. European Journal of Allergy and Clinical Immunology41 citations Open access
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Obesity dysregulates the pulmonary antiviral immune response
M. Almond, H. Farne, M. Jackson, Akhilesh Jha +17 more
2023Nature Communications36 citations Open access
Semantic Scholar
The role of the liver X receptor in chronic obstructive pulmonary disease
A. Higham, S. Lea, J. Plumb, B. Maschera +3 more
2013Respiratory Research36 citations Open access
Semantic Scholar
The effects of repeated Toll-like receptors 2 and 4 stimulation in COPD alveolar macrophages
S. Lea, Sophie Reynolds, M. Kaur, Karen D. Simpson +3 more
2018International Journal of COPD31 citations Open access
Semantic Scholar
Increased Nerve Fiber Expression of Sensory Sodium Channels Nav1.7, Nav1.8, and Nav1.9 in Rhinitis
S. Keh, P. Facer, Karen D. Simpson, G. Sandhu +2 more
2008The Laryngoscope30 citations
Semantic Scholar
Ampicillin resistance in Haemophilus influenzae from COPD patients in the UK
Satyanarayana Maddi, U. Kolsum, Sarah Jackson, R. Barraclough +6 more
2017International Journal of COPD28 citations Open access
Semantic Scholar
A ligand-specific kinetic switch regulates glucocorticoid receptor trafficking and function
P. Trebble, James M. Woolven, Ken A Saunders, Karen D. Simpson +3 more
2013Journal of Cell Science25 citations Open access
Semantic Scholar
The effects of corticosteroids on cytokine production from asthma lung lymphocytes.
M. Kaur, Sophie Reynolds, L. Smyth, Karen D. Simpson +2 more
2014International Immunopharmacology23 citations Open access
Semantic Scholar
The role of CRAC channel in asthma.
M. Kaur, M. Birrell, B. Dekkak, Sophie Reynolds +8 more
2015Pulmonary Pharmacology & Therapeutics7 citations Open access
Semantic Scholar
Lipids in the lung: Respiratory inflammation in COPD
A. Higham, S. Lea, Karen D. Simpson, Dave Singh
20124 citations
Semantic Scholar
The pre-clinical pharmacology of an inhaled PI3Kdelta inhibitor
A. Amour, Vikki Barrett, P. Carter, F. Priest +21 more
20111 citations
Semantic Scholar
An in vitro Co-culture Model to Characterize Cross-talk between COPD Airway Epithelia and Dendritic Cells
Katherine E. Huang, Paul S. Redford, M. Lennon, Karen D. Simpson +3 more
20150 citations
Semantic Scholar
The effect of in vitro culture methods on corticosteroid sensitivity in COPD alveolar macrophages
A. Higham, S. Lea, Karen D. Simpson, Dave Singh
2013European Respiratory Journal0 citations
Semantic Scholar
Trials in asthma : asthma exacerbations and severe asthma P 1782 Use of steroid receptor related STIP 1 gene analysis as an asthma marker
H. Einisman, M. L. Reyes, J. Angulo, M. López-Lastra +17 more
20120 citations
Semantic Scholar
Effect of corticosteroids on lymphocytes from severe asthma patients
M. Kaur, Sophie Reynolds, L. Smyth, S. Hall +3 more
20120 citations
Semantic Scholar
Novel non-steroidal glucocorticoids that dissociate rapid signalling effects from gene transcription
Peter Trebble, Karen D. Simpson, L. Matthews, S. Farrow +1 more
20110 citations
Semantic Scholar
Effect Of Corticosteroids On Lymphocytes From Mild Asthmatics
M. Kaur, L. Smyth, T. Southworth, P. Cadden +3 more
2011Asian Test Symposium0 citations
Semantic Scholar
Induction Of Macrophage Migration Inhibitory Factor (MIF) By Hydrogen Peroxide
Kirsty E. Russell, Simon Hall, Karen D. Simpson, I. Adcock
2011Asian Test Symposium0 citations
Semantic Scholar
The Role Of Liver X Receptor In Chronic Obstructive Lung Disease
A. Higham, S. Lea, J. Plumb, B. Maschera +2 more
2011Asian Test Symposium0 citations
Semantic Scholar

Sophie Reynolds

×5

D. Ray×4

Ken A Saunders×4

E. Hessel×4

A. Higham×4

L. Smyth×4

L. Matthews×3

S. Farrow×3