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G. Virkel · SciRah

Researcher profile · Semantic Scholar

G. Virkel

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G. Virkel — researcher profile on SciRah

h-index: 30
Works: 88
Citations: 2,980

Most-cited papers

Understanding triclabendazole resistance.
G. Brennan, I. Fairweather, A. Trudgett, E. Hoey +12 more
2007Experimental and molecular pathology (Print)243 citations
Semantic Scholar
Comparative plasma disposition kinetics of ivermectin, moxidectin and doramectin in cattle.
C. Lanusse, A. Lifschitz, G. Virkel, L. Alvarez +4 more
1997Journal of Veterinary Pharmacology and Therapeutics226 citations
Semantic Scholar
Comparative distribution of ivermectin and doramectin to parasite location tissues in cattle.
A. Lifschitz, G. Virkel, J. Sallovitz, J. Sutra +3 more
2000Veterinary parasitology193 citations
Semantic Scholar
Ivermectin disposition kinetics after subcutaneous and intramuscular administration of an oil-based formulation to cattle.
A. Lifschitz, G. Virkel, A. Pis, F. Imperiale +4 more
1999Veterinary parasitology108 citations
Semantic Scholar
Strategies to Optimize the Efficacy of Anthelmintic Drugs in Ruminants.
C. Lanusse, C. Cantón, G. Virkel, L. Álvarez +2 more
2018Trends in Parasitology101 citations Open access
Semantic Scholar
Effects of sub-lethal exposure of rats to the herbicide glyphosate in drinking water: glutathione transferase enzyme activities, levels of reduced glutathione and lipid peroxidation in liver, kidneys and small intestine.
K. Larsen, R. Najle, A. Lifschitz, G. Virkel
2012Environmental Toxicology and Pharmacology97 citations Open access
Semantic Scholar
Altered drug influx/efflux and enhanced metabolic activity in triclabendazole-resistant liver flukes
L. Álvarez, H. Solana, M. Mottier, G. Virkel +2 more
2005Parasitology92 citations
Semantic Scholar
MODULATION OF THE P-GLYCOPROTEIN-MEDIATED INTESTINAL SECRETION OF IVERMECTIN: IN VITRO AND IN VIVO ASSESSMENTS
M. Ballent, A. Lifschitz, G. Virkel, J. Sallovitz +1 more
2006Drug Metabolism And Disposition85 citations Open access
Semantic Scholar
Comparative hepatic and extrahepatic enantioselective sulfoxidation of albendazole and fenbendazole in sheep and cattle.
G. Virkel, A. Lifschitz, J. Sallovitz, A. Pis +1 more
2004Drug Metabolism And Disposition84 citations
Semantic Scholar
Comparative tissue pharmacokinetics and efficacy of moxidectin, abamectin and ivermectin in lambs infected with resistant nematodes: Impact of drug treatments on parasite P-glycoprotein expression
M. Lloberas, L. Álvarez, C. Entrocasso, G. Virkel +4 more
2012International Journal for Parasitology: Drugs and Drug Resistance81 citations Open access
Semantic Scholar
Persistence of ivermectin in plasma and faeces following administration of a sustained-release bolus to cattle.
M. Alvinerie, J. Sutra, Pierre Galtier, A. Lifschitz +3 more
1999Research in Veterinary Science81 citations
Semantic Scholar
Ivermectin (3.15%) long-acting formulations in cattle: absorption pattern and pharmacokinetic considerations.
A. Lifschitz, G. Virkel, M. Ballent, J. Sallovitz +3 more
2007Veterinary parasitology75 citations Open access
Semantic Scholar
Moxidectin in cattle: correlation between plasma and target tissues disposition.
A. Lifschitz, G. Virkel, F. Imperiale, J. Sutra +3 more
1999Journal of Veterinary Pharmacology and Therapeutics69 citations
Semantic Scholar
Breed differences on the plasma availability of moxidectin administered pour-on to calves.
J. Sallovitz, A. Lifschitz, F. Imperiale, A. Pis +2 more
2002The Veterinary Journal65 citations
Semantic Scholar
Assessment of the main metabolism pathways for the flukicidal compound triclabendazole in sheep.
G. Virkel, A. Lifschitz, J. Sallovitz, A. Pis +1 more
2006Journal of Veterinary Pharmacology and Therapeutics64 citations Open access
Semantic Scholar
Interference with P-glycoprotein improves ivermectin activity against adult resistant nematodes in sheep.
A. Lifschitz, C. Entrocasso, L. Alvarez, M. Lloberas +5 more
2010Veterinary parasitology63 citations Open access
Semantic Scholar
Clinical efficacy assessment of the albendazole-ivermectin combination in lambs parasitized with resistant nematodes.
C. Entrocasso, L. Alvarez, J. Manazza, A. Lifschitz +4 more
2008Veterinary parasitology63 citations Open access
Semantic Scholar
Bioequivalence of ivermectin formulations in pigs and cattle.
A. Lifschitz, A. Pis, L. Álvarez, G. Virkel +4 more
1999Journal of Veterinary Pharmacology and Therapeutics57 citations
Semantic Scholar
Loperamide-induced enhancement of moxidectin availability in cattle.
A. Lifschitz, G. Virkel, J. Sallovitz, F. Imperiale +2 more
2002Journal of Veterinary Pharmacology and Therapeutics53 citations
Semantic Scholar
Enantiomeric behaviour of albendazole and fenbendazole sulfoxides in domestic animals: pharmacological implications.
B. P. S. Capece, G. Virkel, C. Lanusse
2009The Veterinary Journal47 citations Open access
Semantic Scholar
Evaluation of the interaction between ivermectin and albendazole following their combined use in lambs.
L. Alvarez, A. Lifschitz, C. Entrocasso, J. Manazza +4 more
2008Journal of Veterinary Pharmacology and Therapeutics46 citations
Semantic Scholar
The herbicide glyphosate is a weak inhibitor of acetylcholinesterase in rats.
K. Larsen, A. Lifschitz, C. Lanusse, G. Virkel
2016Environmental Toxicology and Pharmacology44 citations Open access
Semantic Scholar
Hepatic and extra-hepatic metabolic pathways involved in flubendazole biotransformation in sheep.
L. Maté, G. Virkel, A. Lifschitz, M. Ballent +1 more
2008Biochemical Pharmacology44 citations Open access
Semantic Scholar
Involvement of P-glycoprotein on ivermectin kinetic behaviour in sheep: itraconazole-mediated changes on gastrointestinal disposition.
M. Ballent, A. Lifschitz, G. Virkel, J. Sallovitz +1 more
2007Journal of Veterinary Pharmacology and Therapeutics44 citations Open access
Semantic Scholar
Comparative depletion of ivermectin and moxidectin milk residues in dairy sheep after oral and subcutaneous administration
F. Imperiale, A. Lifschitz, J. Sallovitz, G. Virkel +1 more
2004Journal of Dairy Research41 citations
Semantic Scholar
Effects of Sublethal Exposure to a Glyphosate-Based Herbicide Formulation on Metabolic Activities of Different Xenobiotic-Metabolizing Enzymes in Rats
K. Larsen, R. Najle, A. Lifschitz, M. Maté +2 more
2014International journal of toxicology39 citations Open access
Semantic Scholar
Combined use of ivermectin and triclabendazole in sheep: in vitro and in vivo characterisation of their pharmacological interaction.
A. Lifschitz, G. Virkel, M. Ballent, J. Sallovitz +1 more
2009The Veterinary Journal36 citations Open access
Semantic Scholar
A detailed assessment of the pattern of moxidectin tissue distribution after pour-on treatment in calves.
J. Sallovitz, A. Lifschitz, F. Imperiale, G. Virkel +1 more
2003Journal of Veterinary Pharmacology and Therapeutics33 citations
Semantic Scholar
Role of ABC Transporters in Veterinary Medicine: Pharmaco- Toxicological Implications.
G. Virkel, M. Ballent, C. Lanusse, A. Lifschitz
2019Current Medicinal Chemistry32 citations Open access
Semantic Scholar
In vivo and ex vivo assessment of the interaction between ivermectin and danofloxacin in sheep.
M. Ballent, A. Lifschitz, G. Virkel, J. Sallovitz +2 more
2012The Veterinary Journal30 citations Open access
Semantic Scholar
Moxidectin and ivermectin metabolic stability in sheep ruminal and abomasal contents.
A. Lifschitz, G. Virkel, M. Ballent, J. Sallovitz +2 more
2005Journal of Veterinary Pharmacology and Therapeutics30 citations Open access
Semantic Scholar
Albendazole sulphoxide enantiomeric ratios in plasma and target tissues after intravenous administration of ricobendazole to cattle.
C. Cristófol, G. Virkel, L. Álvarez, S. Sánchez +2 more
2001Journal of Veterinary Pharmacology and Therapeutics30 citations
Semantic Scholar
Ivermectin Pharmacokinetics, Metabolism, and Tissue/Egg Residue Profiles in Laying Hens.
L. Moreno, P. Domínguez, C. Farias, L. Canton +5 more
2015Journal of Agricultural and Food Chemistry28 citations Open access
Semantic Scholar
Inhibition of cytochrome P450 activity enhances the systemic availability of triclabendazole metabolites in sheep.
G. Virkel, A. Lifschitz, J. Sallovitz, M. Ballent +2 more
2009Journal of Veterinary Pharmacology and Therapeutics26 citations Open access
Semantic Scholar
Depletion of moxidectin tissue residues in sheep.
A. Lifschitz, F. Imperiale, G. Virkel, M. Muñoz Cobeñas +3 more
2000Journal of Agricultural and Food Chemistry26 citations
Semantic Scholar
Expression differential of microsomal and cytosolic glutathione-S-transferases in Fasciola hepatica resistant at triclabendazole.
S. Scarcella, P. Lamenza, G. Virkel, H. Solana
2012Molecular and biochemical parasitology (Print)25 citations Open access
Semantic Scholar
Combination of cypermethrin and thymol for control of Rhipicephalus microplus: Efficacy evaluation and description of an action mechanism.
C. Tavares, I. C. Sousa, M. N. Gomes, V. Miró +3 more
2021Ticks and Tick-borne Diseases24 citations Open access
Semantic Scholar
Integrated assessment of ivermectin pharmacokinetics, efficacy against resistant Haemonchus contortus and P-glycoprotein expression in lambs treated at three different dosage levels.
L. Álvarez, G. Suárez, L. Ceballos, L. Moreno +6 more
2015Veterinary parasitology24 citations Open access
Semantic Scholar
Accumulation of monepantel and its sulphone derivative in tissues of nematode location in sheep: pharmacokinetic support to its excellent nematodicidal activity.
A. Lifschitz, M. Ballent, G. Virkel, J. Sallovitz +2 more
2014Veterinary parasitology24 citations Open access
Semantic Scholar
Enhanced Plasma Availability of the Metabolites of Albendazole in Fasted Adult Sheep
A. Lifschitz, G. Virkel, M. Mastromarino, C. Lanusse
1997Veterinary research communications24 citations
Semantic Scholar
A pharmacology-based comparison of the activity of albendazole and flubendazole against Echinococcus granulosus metacestode in sheep.
L. Ceballos, G. Virkel, C. Elissondo, C. Cantón +5 more
2013Acta Tropica23 citations Open access
Semantic Scholar
Measurement of triclabendazole and its metabolites in liver flukes: method development and full validation.
L. Mottier, L. Moreno, L. Álvarez, G. Virkel +1 more
2004Journal of Pharmaceutical and Biomedical Analysis22 citations
Semantic Scholar
Albendazole enantiomeric metabolism and binding to cytosolic proteins in the liver fluke Fasciola hepatica
H. Solana, S. Scarcella, G. Virkel, C. Ceriani +2 more
2009Veterinary research communications21 citations Open access
Semantic Scholar
Combination of bioactive phytochemicals and synthetic anthelmintics: In vivo and in vitro assessment of the albendazole-thymol association.
M. V. Miró, C. R. Silva, P. Viviani, S. Luque +5 more
2020Veterinary parasitology20 citations Open access
Semantic Scholar
Comparative pharmacokinetic and pharmacodynamic response of single and double intraruminal doses of ivermectin and moxidectin in nematode-infected lambs
M. Lloberas, L. Alvarez, C. Entrocasso, M. Ballent +4 more
2015New Zealand Veterinary Journal20 citations Open access
Semantic Scholar
Sex‐related differences in the gastrointestinal disposition of ivermectin in the rat: P‐glycoprotein involvement and itraconazole modulation
A. Lifschitz, M. Ballent, G. Virkel, J. Sallovitz +1 more
2006The Journal of pharmacy and pharmacology20 citations Open access
Semantic Scholar
Influence of 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 on expression of P-glycoprotein and cytochrome P450 3A in sheep.
M. Wilkens, L. Maté, N. Schnepel, S. Klinger +4 more
2016Journal of Steroid Biochemistry and Molecular Biology19 citations Open access
Semantic Scholar
Characterization of xenobiotic metabolizing enzymes in bovine small intestinal mucosa.
G. Virkel, M. Carletti, M. Cantiello, L. Della Donna +3 more
2009Journal of Veterinary Pharmacology and Therapeutics17 citations Open access
Semantic Scholar
Plant-Derived Compounds as a Tool for the Control of Gastrointestinal Nematodes: Modulation of Abamectin Pharmacological Action by Carvone
M. V. Miró, S. Luque, P. Cardozo, M. Lloberas +5 more
2020Frontiers in Veterinary Science16 citations Open access
Semantic Scholar
In vitro inhibition of the hepatic S-oxygenation of the anthelmintic albendazole by the natural monoterpene thymol in sheep
V. Miró, A. Lifschitz, P. Viviani, C. Rocha +3 more
2020Xenobiotica; the fate of foreign compounds in biological systems15 citations Open access
Semantic Scholar

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C. Lanusse×44
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C. Lanusse — researcher profile on SciRah
A. Lifschitz×28
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A. Lifschitz — researcher profile on SciRah
J. Sallovitz×18
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J. Sallovitz — researcher profile on SciRah
M. Ballent×16
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M. Ballent — researcher profile on SciRah

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A. Lifschitz — researcher profile on SciRah

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L. Álvarez — researcher profile on SciRah

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A. Pis — researcher profile on SciRah

F. Imperiale×8

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F. Imperiale — researcher profile on SciRah

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L. Alvarez — researcher profile on SciRah

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L. Maté — researcher profile on SciRah

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M. Lloberas — researcher profile on SciRah

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C. Entrocasso — researcher profile on SciRah