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Omar M. Khdour · SciRah

Researcher profile · Semantic Scholar

Omar M. Khdour

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Omar M. Khdour — researcher profile on SciRah

h-index: 14
Works: 37
Citations: 743

Most-cited papers

Mitochondrial Nitroreductase Activity Enables Selective Imaging and Therapeutic Targeting.
A. Chevalier, Yanmin Zhang, Omar M. Khdour, J. B. Kaye +1 more
2016Journal of the American Chemical Society166 citations
Semantic Scholar
Nuclear but not mitochondrial-encoded oxidative phosphorylation genes are altered in aging, mild cognitive impairment, and Alzheimer’s disease
D. Mastroeni, Omar M. Khdour, Elaine Delvaux, J. Nolz +5 more
2016Alzheimer's & Dementia113 citations Open access
Semantic Scholar
Does oxidative stress contribute to the pathology of Friedreich's ataxia? A radical question
J. Armstrong, Omar M. Khdour, S. Hecht
2010The FASEB Journal109 citations
Semantic Scholar
Quinone methide chemistry of prekinamycins: 13C-labeling, spectral global fitting and in vitro studies.
Omar M. Khdour, E. B. Skibo
2009Organic and biomolecular chemistry35 citations
Semantic Scholar
Antiferroptotic Activity of Phenothiazine Analogues: A Novel Therapeutic Strategy for Oxidative Stress Related Disease.
Jun Liu, I. Bandyopadhyay, Lei Zheng, Omar M. Khdour +1 more
2020ACS Medicinal Chemistry Letters27 citations Open access
Semantic Scholar
A Strategy for Suppressing Redox Stress within Mitochondria.
Pablo Arce, Omar M. Khdour, Ruth Goldschmidt, J. Armstrong +1 more
2011ACS Medicinal Chemistry Letters26 citations Open access
Semantic Scholar
Effects of alkyl side chain modification of coenzyme Q10 on mitochondrial respiratory chain function and cytoprotection.
David M Fash, Omar M. Khdour, Sunil Sahdeo, Ruth Goldschmidt +6 more
2013Bioorganic & Medicinal Chemistry20 citations
Semantic Scholar
Design of a cyclopropyl quinone methide reductive alkylating agent. 2.
Omar M. Khdour, A. Ouyang, E. B. Skibo
1998Journal of Organic Chemistry18 citations
Semantic Scholar
Effects of cytoprotective antioxidants on lymphocytes from representative mitochondrial neurodegenerative diseases.
Ruth Goldschmidt, Pablo Arce, Omar M. Khdour, Valérie C. Collin +4 more
2013Bioorganic & Medicinal Chemistry16 citations
Semantic Scholar
Analysis of the structural and mechanistic factors in antioxidants that preserve mitochondrial function and confer cytoprotection.
Pablo Arce, Ruth Goldschmidt, Omar M. Khdour, M. M. Madathil +5 more
2012Bioorganic & Medicinal Chemistry16 citations
Semantic Scholar
Design, synthesis, and evaluation of an α-tocopherol analogue as a mitochondrial antioxidant.
Jun Lu, Omar M. Khdour, J. Armstrong, S. Hecht
2010Bioorganic & Medicinal Chemistry16 citations
Semantic Scholar
Chemistry of pyrrolo[1,2-a]indole- and pyrido[1,2-a]indole-based quinone methides. Mechanistic explanations for differences in cytostatic/cytotoxic properties.
Omar M. Khdour, E. B. Skibo
2007Journal of Organic Chemistry16 citations
Semantic Scholar
An Acetate Prodrug of a Pyridinol-Based Vitamin E Analogue
Omar M. Khdour, Jun Lu, S. Hecht
2011Pharmaceutical Research15 citations
Semantic Scholar
Cytoprotective pyridinol antioxidants as potential therapeutic agents for neurodegenerative and mitochondrial diseases.
M. Alam, Omar M. Khdour, Pablo Arce, Ya-Nan Chen +4 more
2014Bioorganic & Medicinal Chemistry14 citations
Semantic Scholar
Synthesis and evaluation of verticipyrone analogues as mitochondrial complex I inhibitors
Simon Leiris, Omar M. Khdour, Zachary J. Segerman, K. Tsosie +2 more
2010Bioorganic & Medicinal Chemistry14 citations Open access
Semantic Scholar
Novel Antioxidants Protect Mitochondria from the Effects of Oligomeric Amyloid Beta and Contribute to the Maintenance of Epigenome Function
D. Mastroeni, Omar M. Khdour, Pablo Arce, S. Hecht +1 more
2015ACS Chemical Neuroscience13 citations Open access
Semantic Scholar
Lipophilic methylene blue analogues enhance mitochondrial function and increase frataxin levels in a cellular model of Friedreich's ataxia.
Omar M. Khdour, I. Bandyopadhyay, S. Chowdhury, Nishant P. Visavadiya +1 more
2018Bioorganic & Medicinal Chemistry12 citations
Semantic Scholar
An optimized pyrimidinol multifunctional radical quencher.
Omar M. Khdour, Pablo Arce, Basab Roy, S. Hecht
2013ACS Medicinal Chemistry Letters12 citations Open access
Semantic Scholar
Phenothiazine antioxidants increase mitochondrial biogenesis and frataxin levels in Friedreich's ataxia cells.
Omar M. Khdour, I. Bandyopadhyay, Nishant P. Visavadiya, Sandipan Roy Chowdhury +1 more
2018MedChemComm10 citations Open access
Semantic Scholar
Optimization of pyrimidinol antioxidants as mitochondrial protective agents: ATP production and metabolic stability.
A. Chevalier, M. Alam, Omar M. Khdour, Maggie Schmierer +3 more
2016Bioorganic & Medicinal Chemistry9 citations
Semantic Scholar
Selective Functionalization of Antimycin A Through an N-Transacylation Reaction.
A. Chevalier, Yanmin Zhang, Omar M. Khdour, S. Hecht
2016Organic Letters9 citations Open access
Semantic Scholar
Simplified bicyclic pyridinol analogues protect mitochondrial function.
Xiaoqing Cai, Omar M. Khdour, Jennifer Jaruvangsanti, S. Hecht
2012Bioorganic & Medicinal Chemistry8 citations
Semantic Scholar
Novel idebenone analogs block Shc's access to insulin receptor to improve insulin sensitivity.
ChunKiu Hui, A. Tomilov, Chase Garcia, XiaoSong Jiang +9 more
2020Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie7 citations Open access
Semantic Scholar
Synthesis and biological activities of N-(3-carboxylpropyl)-5-amino-2-hydroxy-3-tridecyl-1,4-benzoquinone and analogues.
M. M. Madathil, Omar M. Khdour, Jennifer Jaruvangsanti, S. Hecht
2012Journal of Natural Products7 citations
Semantic Scholar
Lipophilic methylene violet analogues as modulators of mitochondrial function and dysfunction.
Sandipan Roy Chowdhury, Omar M. Khdour, I. Bandyopadhyay, S. Hecht
2017Bioorganic & Medicinal Chemistry6 citations
Semantic Scholar
Influence of substituent heteroatoms on the cytoprotective properties of pyrimidinol antioxidants.
A. Chevalier, Omar M. Khdour, Maggie Schmierer, I. Bandyopadhyay +1 more
2017Bioorganic & Medicinal Chemistry5 citations
Semantic Scholar
Synthesis and characterization of Deltalac-acetogenins that potently inhibit mitochondrial complex I.
Jean Chapuis, Omar M. Khdour, Xiaoqing Cai, Jun Lu +1 more
2009Bioorganic & Medicinal Chemistry5 citations
Semantic Scholar
An assay for DNA polymerase β lyase inhibitors that engage the catalytic nucleophile for binding.
S. Daskalova, B. M. Eisenhauer, Ming-Xuan Gao, Xizhi Feng +6 more
2020Bioorganic & Medicinal Chemistry4 citations
Semantic Scholar
A structurally simplified analogue of geldanamycin exhibits neuroprotective activity.
M. M. Madathil, Omar M. Khdour, Jennifer Jaruvangsanti, S. Hecht
2013ACS Medicinal Chemistry Letters4 citations Open access
Semantic Scholar
Double-component diazeniumdiolate derivatives as anti-cancer agents.
Xun Ji, Qi Chen, Viswanath Arutla, Omar M. Khdour +2 more
2020Bioorganic & Medicinal Chemistry3 citations
Semantic Scholar
Multifunctional radical quenchers as potential therapeutic agents for the treatment of mitochondrial dysfunction.
Xun Ji, Omar M. Khdour, S. Hecht
2019Future Medicinal Chemistry3 citations
Semantic Scholar
Chemical synthesis of lipophilic methylene blue analogues which increase mitochondrial biogenesis and frataxin levels
I. Bandyopadhyay, S. Chowdhury, Nishant P. Visavadiya, S. Hecht +1 more
2018Data in Brief3 citations Open access
Semantic Scholar
Inhibition of Human Cancer Cell Growth by Analogues of Antimycin A
Yanmin Zhang, A. Chevalier, Omar M. Khdour, L. M. Soto +1 more
2017Planta Medica3 citations
Semantic Scholar
EF-P-Mediated Enhancement of Protein Synthesis: Cyclic Dipeptide Incorporation Using Mono- and Bisaminoacylated tRNAs.
Shadow B Harmon, Omar M. Khdour, L. Dedkova, Sidney M. Hecht
2026ACS Chemical Biology0 citations
Semantic Scholar
Functionalized Nitrobenzothiadiazoles as Embedded Fluorescent Probes
Omar M. Khdour, Christina M. Lewis, S. Giridharan, Sidney M. Hecht
2025Journal of Organic Chemistry0 citations
Semantic Scholar
COMPOSÉS PROMÉDICAMENTS ET PROFLUORESCENTS POUR UNE IMAGERIE MITOCHONDRIALE SÉLECTIVE ET UN CIBLAGE THÉRAPEUTIQUE
A. Chevalier, Omar M. Khdour, Yanmin Zhang, S. M. Hecht
20170 citations
Semantic Scholar
Chemistry of Pyrrolo[1,2-a]indole- and Pyrido[1,2-a]indole-Based Quinone Methides. Mechanistic Explanations of Differences in Cytostatic/Cytotoxic Properties.
Omar M. Khdour, E. B. Skibo
20080 citations
Semantic Scholar

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