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K. Metzner · SciRah

Researcher profile · Semantic Scholar

K. Metzner

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K. Metzner — researcher profile on SciRah

h-index: 37
Works: 188
Citations: 5,261

Most-cited papers

Determinants of HIV-1 reservoir size and long-term dynamics during suppressive ART
N. Bachmann, Chantal von Siebenthal, Valentina Vongrad, T. Turk +63 more
2019Nature Communications173 citations Open access
Semantic Scholar
V-pipe: a computational pipeline for assessing viral genetic diversity from high-throughput data
Susana Posada-Céspedes, David Seifert, I. Topolsky, K. Jablonski +2 more
2021Bioinform.75 citations Open access
Semantic Scholar
Tracing HIV-1 strains that imprint broadly neutralizing antibody responses
R. Kouyos, P. Rusert, Claus Kadelka, M. Huber +61 more
2018Nature57 citations Open access
Semantic Scholar
MinVar: A rapid and versatile tool for HIV-1 drug resistance genotyping by deep sequencing.
M. Huber, K. Metzner, Fabienne-Desirée Geissberger, Cyril Shah +5 more
2017Journal of Virological Methods55 citations Open access
Semantic Scholar
Low-abundance drug-resistant HIV-1 variants in antiretroviral drug-naïve individuals: A systematic review of detection methods, prevalence, and clinical impact.
H. A. Mbunkah, S. Bertagnolio, R. Hamers, G. Hunt +6 more
2019Journal of Infectious Diseases49 citations Open access
Semantic Scholar
Population pharmacokinetics of dolutegravir: influence of drug-drug interactions in a real-life setting.
Catalina Barceló, M. Aouri, Perrine Courlet, M. Guidi +58 more
2019Journal of Antimicrobial Chemotherapy39 citations Open access
Semantic Scholar
EBV renders B cells susceptible to HIV-1 in humanized mice
Donal McHugh, R. Myburgh, N. Caduff, M. Spohn +30 more
2020Life Science Alliance34 citations Open access
Semantic Scholar
Reversal of T Cell Exhaustion in Chronic HCV Infection
Sylwia Osuch, K. Metzner, Kamila Caraballo Cortés
2020Viruses33 citations Open access
Semantic Scholar
Efficacy and safety of dolutegravir plus emtricitabine versus standard ART for the maintenance of HIV-1 suppression: 48-week results of the factorial, randomized, non-inferiority SIMPL’HIV trial
D. Sculier, G. Wandeler, S. Yerly, A. Marinosci +13 more
2020PLoS Medicine30 citations Open access
Semantic Scholar
Viral Diversity Based on Next-Generation Sequencing of HIV-1 Provides Precise Estimates of Infection Recency and Time Since Infection.
Louisa A. Carlisle, T. Turk, K. Kusejko, K. Metzner +69 more
2019Journal of Infectious Diseases29 citations Open access
Semantic Scholar
Delineating CD4 dependency of HIV-1: Adaptation to infect low level CD4 expressing target cells widens cellular tropism but severely impacts on envelope functionality
David Beauparlant, P. Rusert, Carsten Magnus, Claus Kadelka +9 more
2017PLoS Pathogens29 citations Open access
Semantic Scholar
Technologies for HIV-1 drug resistance testing: inventory and needs
K. Metzner
2022Current Opinion in HIV and AIDS28 citations Open access
Semantic Scholar
Parallel Evolution of HIV-1 in a Long-Term Experiment
Frederic Bertels, Christine Leemann, K. Metzner, Roland R. Regoes
2019Molecular biology and evolution28 citations Open access
Semantic Scholar
Decrease of T-cells exhaustion markers programmed cell death-1 and T-cell immunoglobulin and mucin domain-containing protein 3 and plasma IL-10 levels after successful treatment of chronic hepatitis C
Sylwia Osuch, T. Laskus, H. Berak, Karol Perlejewski +4 more
2020Scientific Reports25 citations Open access
Semantic Scholar
Preclinical Evaluation of a Novel TALEN Targeting CCR5 Confirms Efficacy and Safety in Conferring Resistance to HIV‐1 Infection
M. Romito, A. Juillerat, Yik-Lim Kok, Markus Hildenbeutel +10 more
2020Biotechnology Journal25 citations Open access
Semantic Scholar
Long-term Immune Response to Yellow Fever Vaccination in Human Immunodeficiency Virus (HIV)–Infected Individuals Depends on HIV RNA Suppression Status: Implications for Vaccination Schedule
O. Veit, C. Domingo, M. Niedrig, C. Staehelin +61 more
2018Clinical Infectious Diseases25 citations Open access
Semantic Scholar
How helpful are the European AIDS Clinical Society cognitive screening questions in predicting cognitive impairment in an aging, well‐treated HIV‐positive population?
M. Métral, I. Nadin, I. Locatelli, P. Tarr +110 more
2019HIV Medicine24 citations Open access
Semantic Scholar
Targeted shock-and-kill HIV-1 gene therapy approach combining CRISPR activation, suicide gene tBid and retargeted adenovirus delivery
Sarah Klinnert, C. Schenkel, P. C. Freitag, H. Günthard +2 more
2023Gene Therapy22 citations Open access
Semantic Scholar
Low prevalence of transmitted HIV-1 drug resistance detected by a dried blood spot (DBS)-based next-generation sequencing (NGS) method in newly diagnosed individuals in Cameroon in the years 2015–16
H. A. Mbunkah, A. Marzel, S. Schmutz, Yik-Lim Kok +10 more
2018Journal of Antimicrobial Chemotherapy19 citations Open access
Semantic Scholar
Rapid decline of anti‐hepatitis C virus (HCV) antibodies following early treatment of incident HCV infections in HIV‐infected men who have sex with men
K. Aebi-Popp, G. Wandeler, L. Salazar-Vizcaya, K. Metzner +9 more
2018HIV Medicine19 citations
Semantic Scholar
Transfer of antiretroviral drugs into breastmilk: a prospective study from the Swiss Mother and Child HIV Cohort Study
K. Aebi-Popp, C. Kahlert, P. Crisinel, L. Decosterd +56 more
2022Journal of Antimicrobial Chemotherapy18 citations Open access
Semantic Scholar
HIV-1 integration sites in CD4+ T cells during primary, chronic, and late presentation of HIV-1 infection
Yik-Lim Kok, Valentina Vongrad, SE Chaudron, M. Shilaih +9 more
2021JCI Insight18 citations Open access
Semantic Scholar
Changing Trends in International Versus Domestic HCV Transmission in HIV-Positive Men Who Have Sex With Men: A Perspective for the Direct-Acting Antiviral Scale-Up Era
L. Salazar-Vizcaya, R. Kouyos, K. Metzner, Kamila Caraballo Cortés +62 more
2019Journal of Infectious Diseases18 citations Open access
Semantic Scholar
HIV-1 Low-Level Viremia Predicts Viral Failure in Participants on Antiretroviral Therapy in the Swiss HIV Cohort Study
Caroline Lanz, Janne Meier, M. Stöckle, H. Furrer +62 more
2024Clinical Infectious Diseases17 citations Open access
Semantic Scholar
Real-life management of drug-drug interactions between antiretrovirals and statins.
Perrine Courlet, F. Livio, Susana Alves Saldanha, A. Scherrer +57 more
2020Journal of Antimicrobial Chemotherapy15 citations Open access
Semantic Scholar
Stable HIV‐1 reservoirs on dolutegravir maintenance monotherapy: the MONODO study
D. Sculier, T. Doco-Lecompte, S. Yerly, K. Metzner +2 more
2018HIV Medicine15 citations Open access
Semantic Scholar
Convergent evolution as an indicator for selection during acute HIV-1 infection
Frederic Bertels, K. Metzner, Roland R. Regoes
2018bioRxiv15 citations Open access
Semantic Scholar
Unravelling HIV-1 Latency, One Cell at a Time.
Yik-Lim Kok, A. Ciuffi, K. Metzner
2017Trends in Microbiology15 citations
Semantic Scholar
Non-inferiority of simplified dolutegravir monotherapy compared to continued combination antiretroviral therapy that was initiated during primary HIV infection: a randomized, controlled, multi-site, open-label, non-inferiority trial.
D. Braun, T. Turk, Fabian Tschumi, Christina Grube +17 more
2019Clinical Infectious Diseases14 citations Open access
Semantic Scholar
Frequency matters: comparison of drug resistance mutation detection by Sanger and next-generation sequencing in HIV-1.
S. Balakrishna, T. Loosli, M. Zaheri, Paul Frischknecht +20 more
2023Journal of Antimicrobial Chemotherapy13 citations Open access
Semantic Scholar
Emergence of Resistance to Integrase Strand Transfer Inhibitors during Dolutegravir Containing Triple-Therapy in a Treatment-Experienced Patient with Pre-Existing M184V/I Mutation
D. Braun, T. Scheier, U. Ledermann, M. Flepp +3 more
2020Viruses13 citations Open access
Semantic Scholar
The influence of human genetic variation on Epstein–Barr virus sequence diversity
S. Rüeger, C. Hammer, Alexis Loetscher, Paul J. McLaren +62 more
2020Scientific Reports13 citations Open access
Semantic Scholar
V-pipe: a computational pipeline for assessing viral genetic diversity from high-throughput sequencing data
Susana Posada-Céspedes, David Seifert, I. Topolsky, K. Metzner +1 more
2020bioRxiv13 citations Open access
Semantic Scholar
Prevalence of integrase strand transfer inhibitor resistance mutations in antiretroviral-naive HIV-1-infected individuals in Cameroon.
Benjamin M Wenk, H. A. Mbunkah, Ndi N. Nsanwe, E. Mbu +5 more
2020Journal of Antimicrobial Chemotherapy12 citations Open access
Semantic Scholar
Long-term experimental evolution of HIV-1 reveals effects of environment and mutational history
Eva Bons, Christine Leemann, K. Metzner, Roland R. Regoes
2020PLoS Biology11 citations Open access
Semantic Scholar
Prevalence of HIV-1 drug resistance mutations in proviral DNA in the Swiss HIV Cohort Study, a retrospective study from 1995 to 2018
Bashkim Jaha, C. Schenkel, Lisa Jörimann, M. Huber +8 more
2023Journal of Antimicrobial Chemotherapy10 citations Open access
Semantic Scholar
Heritability of the HIV-1 reservoir size and decay under long-term suppressive ART
Chen-Kai Wan, N. Bachmann, Venelin Mitov, F. Blanquart +20 more
2020Nature Communications10 citations Open access
Semantic Scholar
Impact of pretreatment low-abundance HIV-1 drug-resistant variants on virological failure among HIV-1/TB-co-infected individuals
B. Chimukangara, Jennifer Giandhari, R. Lessells, N. Yende-Zuma +9 more
2020Journal of Antimicrobial Chemotherapy10 citations Open access
Semantic Scholar
Sustained Viral Suppression With Dolutegravir Monotherapy Over 192 Weeks in Patients Starting Combination Antiretroviral Therapy During Primary Human Immunodeficiency Virus Infection (EARLY-SIMPLIFIED): A Randomized, Controlled, Multi-site, Noninferiority Trial
Emily West, Marius Zeeb, Christina Grube, H. Kuster +9 more
2023Clinical Infectious Diseases9 citations Open access
Semantic Scholar
No Effect of Pegylated Interferon-&agr; on Total HIV-1 DNA Load in HIV-1/HCV Coinfected Patients
Victoria P. Strouvelle, D. Braun, Valentina Vongrad, A. Scherrer +59 more
2018Journal of Infectious Diseases9 citations Open access
Semantic Scholar
Spontaneous reactivation of latent HIV-1 promoters is linked to the cell cycle as revealed by a genetic-insulators-containing dual-fluorescence HIV-1-based vector
Yik-Lim Kok, S. Schmutz, Anne Inderbitzin, Kathrin Neumann +8 more
2018Scientific Reports9 citations Open access
Semantic Scholar
Comparative Evaluation of Open-Source Bioinformatics Pipelines for Full-Length Viral Genome Assembly
Levente Zsichla, Marius Zeeb, Dávid Fazekas, Éva Áy +4 more
2024Viruses8 citations Open access
Semantic Scholar
A systematic molecular epidemiology screen reveals numerous HIV-1 superinfections in the Swiss HIV Cohort Study.
SE Chaudron, Christine Leemann, K. Kusejko, Huyen Nguyen +17 more
2022Journal of Infectious Diseases8 citations Open access
Semantic Scholar
Dolutegravir Monotherapy as Maintenance Strategy: A Meta-Analysis of Individual Participant Data From Randomized Controlled Trials
A. Fournier, L. Hocqueloux, D. Braun, K. Metzner +10 more
2022Open Forum Infectious Diseases8 citations Open access
Semantic Scholar
Importance of routine viral load monitoring: higher levels of resistance at ART failure in Uganda and Lesotho compared with Switzerland
N. Bachmann, A. von Braun, ND Labhardt, Claus Kadelka +62 more
2018Journal of Antimicrobial Chemotherapy8 citations Open access
Semantic Scholar
Considerations and limitations for establishing an Intact Proviral DNA Assay (IPDA) on a chip-based digital PCR system for HIV-1 reservoir quantification.
Jasmin Tschumi, Kathrin Neumann, Dominique L. Braun, H. Günthard +1 more
2025Journal of Virological Methods7 citations Open access
Semantic Scholar
T-Cell Exhaustion in HIV-1/Hepatitis C Virus Coinfection Is Reduced After Successful Treatment of Chronic Hepatitis C
Kamila Caraballo Cortés, Sylwia Osuch, Karol Perlejewski, M. Radkowski +7 more
2023Open Forum Infectious Diseases7 citations Open access
Semantic Scholar
Sexual Behaviour and STI Incidence in Sexually Active MSM Living With HIV in Times of COVID-19
C. Mugglin, Kalongo Hamusonde, Luisa Salazar-Vizcaya, Katharina Kuseijko +66 more
2023Open Forum Infectious Diseases7 citations Open access
Semantic Scholar
Systematic HIV-1 promoter targeting with CRISPR/dCas9-VPR reveals optimal region for activation of the latent provirus.
Sarah Klinnert, Alex Chemnitzer, P. Rusert, K. Metzner
2022Journal of General Virology7 citations
Semantic Scholar
Host genomics of the HIV-1 reservoir size and its decay rate during suppressive antiretroviral treatment
C. Thorball, A. Borghesi, N. Bachmann, Chantal von Siebenthal +22 more
20197 citations Open access
Semantic Scholar

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