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M. Hashimoto · SciRah

Researcher profile · Semantic Scholar

M. Hashimoto

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M. Hashimoto — researcher profile on SciRah

h-index: 15
Works: 44
Citations: 1,147

Most-cited papers

Emergence and takeover of YMDD motif mutant hepatitis B virus during long‐term lamivudine therapy and re‐takeover by wild type after cessation of therapy
K. Chayama, Yoshiyuki Suzuki, Masahiro Kobayashi, Mizuho Kobayashi +11 more
1998Hepatology389 citations
Semantic Scholar
Pretreatment virus load and multiple amino acid substitutions in the interferon sensitivity–determining region predict the outcome of interferon treatment in patients with chronic genotype 1b hepatitis C virus infection
K. Chayama, A. Tsubota, Mizuho Kobayashi, K. Okamoto +10 more
1997Hepatology204 citations
Semantic Scholar
Genetic Polymorphism of the MxA Gene Promoter and Interferon Responsiveness of Hepatitis C Patients: Revisited by Analyzing Two SNP Sites (–123 and –88) in vivo and in vitro
M. Hijikata, S. Mishiro, C. Miyamoto, Y. Furuichi +2 more
2002Intervirology83 citations
Semantic Scholar
SNPs in the promoter region of the osteopontin gene as a marker predicting the efficacy of interferon-based therapies in patients with chronic hepatitis C
M. Naito, A. Matsui, M. Inao, S. Nagoshi +7 more
2005Journal of gastroenterology63 citations
Semantic Scholar
Genetic polymorphims in promoter region of osteopontin gene may be a marker reflecting hepatitis activity in chronic hepatitis C patients.
S. Mochida, M. Hashimoto, A. Matsui, M. Naito +6 more
2004Biochemical and Biophysical Research Communications - BBRC49 citations
Semantic Scholar
The dinucleotide microsatellite polymorphism of the IFNAR1 gene promoter correlates with responsiveness of hepatitis C patients to interferon.
N. Matsuyama, S. Mishiro, M. Sugimoto, Y. Furuichi +3 more
2003Hepatology Research48 citations
Semantic Scholar
In situ hybridization AT-tailing with catalyzed signal amplification for sensitive and specific in situ detection of human immunodeficiency virus-1 mRNA in formalin-fixed and paraffin-embedded tissues.
N. Nakajima, P. Ionescu, Yuko Sato, M. Hashimoto +4 more
2003American Journal of Pathology32 citations Open access
Semantic Scholar
Susceptibility of TT virus to interferon therapy.
K. Chayama, M. Kobayashi, A. Tsubota, Y. Arase +9 more
1999Journal of General Virology31 citations Open access
Semantic Scholar
Genotype, slow decrease in virus titer during interferon treatment and high degree of sequence variability of hypervariable region are indicative of poor response to interferon treatment in patients with chronic hepatitis type C.
K. Chayama, A. Tsubota, Y. Arase, S. Saitoh +7 more
1995Journal of Hepatology28 citations
Semantic Scholar
Prevalence of TT virus before and after blood transfusion in patients with chronic liver disease treated surgically for hepatocellular carcinoma
Masahiro Kobayashi, K. Chayama, Y. Arase, Mizuho Kobayashi +9 more
1999Journal of Gastroenterology and Hepatology23 citations
Semantic Scholar
A pilot study of corticosteroid priming for lymphoblastoid interferon alfa in patients with chronic hepatitis C
K. Chayama, A. Tsubota, Mizuho Kobayashi, M. Hashimoto +8 more
1996Hepatology21 citations Open access
Semantic Scholar
Fluctuations of hepatitis C virus load are not related to amino acid substitutions in hypervariable region 1 and interferon sensitivity determining region
M. Hashimoto, K. Chayama, Masahiro Kobayashi, A. Tsubota +9 more
1999Journal of Medical Virology18 citations
Semantic Scholar
Predictive factors in eradicating hepatitis C virus using a relatively small dose of interferon
M. Fukuda, K. Chayama, A. Tsubota, Masahiro Kobayashi +10 more
1998Journal of Gastroenterology and Hepatology17 citations
Semantic Scholar
Typing six major hepatitis C virus genotypes by polymerase chain reaction using primers derived from nucleotide sequences of the NS5 region
M. Hashimoto, K. Chayama, A. Tubota, Masahiro Kobayashi +10 more
199616 citations
Semantic Scholar
Antiviral effect of lymphoblastoid interferon‐alpha on hepatitis C virus in patients with chronic hepatitis type C
K. Chayama, Y. Arase, I. Koida, A. Tsubota +10 more
1994Journal of Gastroenterology and Hepatology15 citations
Semantic Scholar
Enzyme-linked immunosorbent assay to detect hepatitis C virus serological groups 1 to 6
Mariko Kobayashi, K. Chayama, Y. Arase, A. Tsubota +8 more
1999Journal of gastroenterology14 citations
Semantic Scholar
Construction of an electrochemical DNA chip for simultaneous genotyping of single nucleotide polymorphisms.
Masayoshi Takahashi, Jun Okada, Keiko Ito, M. Hashimoto +6 more
2005In Analysis13 citations
Semantic Scholar
Development of multisample detection system using a tag insertion primer and an electrochemical DNA chip
N. Nakamura, Keiko Ito, M. Hashimoto, Akiyoshi Nakamura +5 more
2011Analytical Biochemistry12 citations Open access
Semantic Scholar
Electrochemical DNA array for simultaneous genotyping of single-nucleotide polymorphisms associated with the therapeutic effect of interferon.
Masayoshi Takahashi, Jun Okada, Keiko Ito, M. Hashimoto +6 more
2004Clinical Chemistry11 citations
Semantic Scholar
Nucleotide sequences of hepatitis GB virus C. Identification of highly conserved domains in the 5′ noncoding region and detection by polymerase chain reaction
K. Chayama, J. Menon, K. Okamoto, M. Hashimoto +5 more
199710 citations
Semantic Scholar
Predictive value of different hepatitis C serological assays in the treatment of chronic hepatitis C with interferon α
Mariko Kobayashi, K. Chayama, Y. Arase, A. Tsubota +9 more
1999Journal of gastroenterology9 citations
Semantic Scholar
A novel bioprinting application for the production of reference material containing a defined copy number of target DNA.
Manabu Seo, R. Takabatake, S. Izumi, Hirotaka Unno +15 more
2019Analytical Chemistry8 citations Open access
Semantic Scholar
Biochemical and histological features of hepatitis G virus infection
Masahiro Kobayashi, K. Chayama, M. Fukuda, A. Tsubota +11 more
1998Journal of Gastroenterology and Hepatology7 citations
Semantic Scholar
Prevalence of HCV genotype among patients with chronic liver diseases in the Tokyo metropolitan area
Mariko Kobayashi, H. Kumada, K. Chayama, Y. Arase +6 more
1994Journal of gastroenterology6 citations
Semantic Scholar
Evaluation method for asymmetric uncertainty of quantitative polymerase chain reaction measurements of deoxyribonucleic acids with low copy number
Unoh Ki, T. Suzuki, S. Nakazawa, Yuuki Yonekawa +4 more
2021Scientific Reports5 citations Open access
Semantic Scholar
Improved rapid and efficient method for Staphylococcus aureus DNA extraction from milk for identification of mastitis pathogens
Hirotaka Unno, Mika Inada, Akiyoshi Nakamura, M. Hashimoto +9 more
2015Journal of Veterinary Medical Science5 citations Open access
Semantic Scholar
Hepatitis G virus infection after blood transfusion in patients with chronic liver disease treated surgically for hepatocellular carcinoma
Masahiro Kobayashi, K. Chayama, Y. Arase, M. Fukuda +11 more
19973 citations
Semantic Scholar
Genotyping of hepatitis C virus by the polymerase chain reaction: a comparison of two PCR-based methods using core or NS5 primers
M. Hashimoto, K. Chayama, A. Tubota, I. Koida +10 more
19953 citations
Semantic Scholar
Usefulness of hepatitis C virus RNA counts by second generation HCV bDNA-probe in chronic hepatitis C based on the HCV genotype
Mariko Kobayashi, H. Kumada, Y. Arase, K. Chayama +12 more
1998Journal of gastroenterology2 citations
Semantic Scholar
Classification of hepatitis C virus genotype.Comparison by NS5 and core methods.
M. Hashimoto
19941 citations Open access
Semantic Scholar
Effect of reduction agents on determination of mercury by atomic absorption method
S. Shimomura, Yoshiko Fukumoto, M. Hashimoto, Y. Tanase
19701 citations Open access
Semantic Scholar
Atypical length of the TRIF polyproline track possibly associated with spontaneous clearance of HCV RNA
M. Hashimoto, M. Arai, S. Mishiro
20060 citations Open access
Semantic Scholar
Genomics research in the liver. 3. Prognosis of chronic hepatitis C. MxA, osteopontin promoter SNP and activity of hepatitis.
S. Mishiro, M. Arai, M. Hashimoto
20050 citations Open access
Semantic Scholar
Technical Advance In Situ Hybridization AT-Tailing with Catalyzed Signal Amplification for Sensitive and Specific in Situ Detection of Human Immunodeficiency Virus-1 mRNA in Formalin-Fixed and Paraffin-Embedded Tissues
N. Nakajima, P. Ionescu, Yuko Sato, M. Hashimoto +4 more
20030 citations
Semantic Scholar
55 Genetic polymorphisms in promoter region of osteopontin gene as a marker to determine hepatitis activity in patients with chronic hepatitis C
A. Matsui, S. Mochida, M. Naito, M. Inao +4 more
20030 citations
Semantic Scholar
Subject Index Vol. 44, 2001
F. Burlandy, M. Rebello, Yan Zhou, C. Pyne +58 more
2002Intervirology0 citations
Semantic Scholar
Sonde polynucleotidique et amorce originaire du virus de l'hepatite e des japonais, puces pourvues de cette sonde, kits dotes de cette sonde et procede pour detecter le virus de l'hepatite e au moyen de cette sonde
Kazuaki Takahashi, S. Mishiro, Y. Oota, M. Hashimoto +1 more
20020 citations
Semantic Scholar
Contents Vol. 44, 2001
F. Burlandy, M. Rebello, Yan Zhou, C. Pyne +58 more
2002Intervirology0 citations Open access
Semantic Scholar
Study of TT virus quantitative system.
M. Hashimoto
19980 citations Open access
Semantic Scholar
Determination system of GBV-C hepatitis virus.
M. Hashimoto
19960 citations Open access
Semantic Scholar
The non-effect of anti-interferon alpha-2a antibody on the response to inerferon therapy.
Masahiro Kobayashi, K. Chayama, Y. Arase, A. Tsubota +11 more
19960 citations Open access
Semantic Scholar
P-21 Genetic drift of hepatitis B virus precore/core region in long-term follow-up of asymptomatic HBe-Ag-positive carriers
A. Tsubota, K. Chayama, Y. Arase, I. Koida +8 more
19950 citations
Semantic Scholar
Base sequence of 3a type detected from Pakistani staying in Japan and genotyping method of 6 kinds of hepatitis C viruses.
M. Hashimoto
19950 citations Open access
Semantic Scholar
Quantitative analysis of hepatitis C virus RNA by competitive nested polymerase chain reaction. Comparison of various internal standard.
T. Odagawa, K. Chayama, Y. Arase, A. Tsubota +8 more
19940 citations Open access
Semantic Scholar

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