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P. Karpowicz · SciRah

Researcher profile · Semantic Scholar

P. Karpowicz

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P. Karpowicz — researcher profile on SciRah

h-index: 9
Works: 23
Citations: 285

Most-cited papers

Genetic and pharmacologic proteasome augmentation ameliorates Alzheimer’s-like pathology in mouse and fly APP overexpression models
E. S. Chocron, Erin Munkácsy, Harper S. Kim, P. Karpowicz +12 more
2022Science Advances52 citations Open access
Semantic Scholar
Proline- and Arginine-Rich Peptides as Flexible Allosteric Modulators of Human Proteasome Activity
M. Giżyńska, Julia Witkowska, P. Karpowicz, R. Rostankowski +5 more
2018Journal of Medicinal Chemistry45 citations Open access
Semantic Scholar
The proteasome in health and disease.
E. Jankowska, J. Stój, P. Karpowicz, P. Osmulski +1 more
2012Current pharmaceutical design42 citations
Semantic Scholar
Development of a Peptide Derived from Platelet-Derived Growth Factor (PDGF-BB) into a Potential Drug Candidate for the Treatment of Wounds
M. Deptuła, P. Karpowicz, Anna Wardowska, P. Sass +20 more
2020Advances in wound care40 citations Open access
Semantic Scholar
Crystal structure of a low molecular weight activator Blm-pep with yeast 20S proteasome – insights into the enzyme activation mechanism
Julia Witkowska, M. Giżyńska, P. Grudnik, P. Golik +4 more
2017Scientific Reports27 citations Open access
Semantic Scholar
New Peptide-Based Pharmacophore Activates 20S Proteasome
P. Osmulski, P. Karpowicz, E. Jankowska, J. Bohmann +2 more
2020Molecules23 citations Open access
Semantic Scholar
Interplay between Structure and Charge as a Key to Allosteric Modulation of Human 20S Proteasome by the Basic Fragment of HIV-1 Tat Protein
P. Karpowicz, P. Osmulski, Julia Witkowska, E. Sikorska +4 more
2015PLoS ONE12 citations Open access
Semantic Scholar
Peptidomimetics Based on C-Terminus of Blm10 Stimulate Human 20S Proteasome Activity and Promote Degradation of Proteins
Katarzyna Cekała, Karolina Trepczyk, Daria Sowik, P. Karpowicz +5 more
2022Biomolecules11 citations Open access
Semantic Scholar
Dissecting a role of a charge and conformation of Tat2 peptide in allosteric regulation of 20S proteasome
Julia Witkowska, P. Karpowicz, M. Gaczynska, P. Osmulski +1 more
2014Journal of Peptide Science11 citations
Semantic Scholar
AFM Imaging Reveals Topographic Diversity of Wild Type and Z Variant Polymers of Human α1-Proteinase Inhibitor
M. Gaczynska, P. Karpowicz, C. Stuart, Malgorzata G. Norton +3 more
2016PLoS ONE8 citations Open access
Semantic Scholar
Pressure as a denaturing agent in studies of single‐point mutants of an amyloidogenic protein human cystatin c
E. Jankowska, P. Stefanowicz, M. Sosnowska, P. Karpowicz +3 more
2012Proteins: Structure, Function, and Bioinformatics6 citations
Semantic Scholar
Blm10-Based Compounds Add to the Knowledge of How Allosteric Modulators Influence Human 20S Proteasome
Julia Witkowska, Małgorzata Giżyńska, P. Karpowicz, Daria Sowik +8 more
2025ACS Chemical Biology5 citations Open access
Semantic Scholar
Oligomers and peptidomimetics consisting of methyl 3-amino-2,3-dideoxyhexopyranosiduronic acids
E. Sikorska, Dorota Tuwalska, P. Karpowicz, E. Jankowska +2 more
20152 citations
Semantic Scholar
Crystal structure of a low molecular weight activator Blm-pep with yeast 20S proteasome – insights into the enzyme activation mechanism
Julia Witkowska, M. Giżyńska, P. Grudnik, P. Golik +4 more
2017Scientific Reports1 citations Open access
Semantic Scholar
PDGF-DERIVED PEPTIDES: FROM RECEPTOR BINDING TO CELLULAR SIGNALING IN WOUND HEALING
Krzysztof Polaczek, P. Karpowicz, M. Zawrzykraj, M. Deptuła +4 more
2026Proceedings of the 38th European Peptide Symposium0 citations Open access
Semantic Scholar
Determination of the Binding Sites of Activators within the Proteasome Structure
M. Giżyńska, Julia Witkowska, P. Karpowicz, F. Henneberg +3 more
2019Proceedings0 citations Open access
Semantic Scholar
Regulation of Proteasomal Catalytic Activity by Altering its Protein-Protein Interactions
P. Osmulski, P. Karpowicz, Matthew B. Giletto, Corey L Jones +6 more
20170 citations Open access
Semantic Scholar
From Single Molecules to Single Cells: Biophysics of Interactions between Small Regulators and Proteasome
P. Osmulski, P. Karpowicz, E. Jankowska, Matthew B. Giletto +4 more
20160 citations Open access
Semantic Scholar
Structural Dynamics of Proteasome: AFM Perspective
P. Osmulski, SenLi Guo, P. Karpowicz, M. Gaczynska
20140 citations Open access
Semantic Scholar
HIV-1 Tat-derived peptides as allosteric inhibitors of the proteasome activity
J. Stój, P. Karpowicz, M. Gaczynska, P. Osmulski +1 more
20130 citations
Semantic Scholar
In search for effective modulators of the proteasome activity
P. Karpowicz, J. Stój, M. Gaczynska, P. Osmulski +1 more
20130 citations
Semantic Scholar
Atomic Force Microscopy reveals Diversity of Serpin Polymers
P. Osmulski, M. Gaczynska, P. Karpowicz, C. Stuart +4 more
20130 citations Open access
Semantic Scholar
Proteolityczny kombinat i jego regulatory
J. Stój, P. Karpowicz
20120 citations
Semantic Scholar

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P. Osmulski×13
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