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S. Ullrich · SciRah

Researcher profile · Semantic Scholar

S. Ullrich

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S. Ullrich — researcher profile on SciRah

h-index: 42
Works: 123
Citations: 4,885

Most-cited papers

T-helper-1-cell cytokines drive cancer into senescence
H. Braumüller, T. Wieder, E. Brenner, Sonja Assmann +26 more
2013Nature691 citations Open access
Semantic Scholar
Dexamethasone Induces Cell Death in Insulin-Secreting Cells, an Effect Reversed by Exendin-4
F. Ranta, D. Avram, S. Berchtold, M. Düfer +3 more
2006Diabetes195 citations
Semantic Scholar
Serum- and glucocorticoid-inducible kinase 1 (SGK1) mediates glucocorticoid-induced inhibition of insulin secretion.
S. Ullrich, S. Berchtold, F. Ranta, G. Seebohm +11 more
2005Diabetes187 citations
Semantic Scholar
Metabolic implications of pancreatic fat accumulation
R. Wagner, Sabine S. Eckstein, H. Yamazaki, F. Gerst +11 more
2021Nature Reviews Endocrinology157 citations
Semantic Scholar
Metabolic crosstalk between fatty pancreas and fatty liver: effects on local inflammation and insulin secretion
F. Gerst, R. Wagner, G. Kaiser, M. Panse +14 more
2017Diabetologia136 citations Open access
Semantic Scholar
Discovery of potent and selective agonists for the free fatty acid receptor 1 (FFA(1)/GPR40), a potential target for the treatment of type II diabetes.
E. Christiansen, Christian Urban, Nicole Merten, Kathrin Liebscher +9 more
2008Journal of Medicinal Chemistry126 citations Open access
Semantic Scholar
Fenamates as TRP channel blockers: mefenamic acid selectively blocks TRPM3
Chihab Klose, Isabelle Straub, M. Riehle, F. Ranta +4 more
2011British Journal of Pharmacology114 citations Open access
Semantic Scholar
Inhibition of insulin secretion via distinct signaling pathways in alpha2-adrenoceptor knockout mice.
Melanie Peterhoff, A. Sieg, M. Brede, Cho-Ming Chao +2 more
2003European Journal of Endocrinology108 citations
Semantic Scholar
cAMP-activated protein kinase-independent potentiation of insulin secretion by cAMP is impaired in SUR1 null islets.
M. Nakazaki, A. Crane, Min Hu, V. Seghers +3 more
2002Diabetes107 citations Open access
Semantic Scholar
Intracellular multiplication of Legionella pneumophila depends on host cell amino acid transporter SLC1A5
H. Wieland, S. Ullrich, F. Lang, B. Neumeister
2005Molecular Microbiology90 citations
Semantic Scholar
Loss of Annexin A7 Leads to Alterations in Frequency-Induced Shortening of Isolated Murine Cardiomyocytes
C. Herr, N. Smyth, S. Ullrich, Fang-Li Yun +9 more
2001Molecular and Cellular Biology84 citations Open access
Semantic Scholar
What role do fat cells play in pancreatic tissue?
F. Gerst, R. Wagner, M. B. Oquendo, D. Siegel-Axel +5 more
2019Molecular Metabolism79 citations Open access
Semantic Scholar
Impact of the Adipokine Adiponectin and the Hepatokine Fetuin-A on the Development of Type 2 Diabetes: Prospective Cohort- and Cross-Sectional Phenotyping Studies
N. Stefan, Qi Sun, A. Fritsche, J. Machann +9 more
2014PLoS ONE78 citations Open access
Semantic Scholar
Ceramide formation as a target in beta-cell survival and function
F. Lang, S. Ullrich, E. Gulbins
2011Expert opinion on therapeutic targets78 citations
Semantic Scholar
Glucose homeostasis is regulated by pancreatic β-cell cilia via endosomal EphA-processing
Francesco Volta, M. Scerbo, A. Seelig, R. Wagner +7 more
2019Nature Communications72 citations Open access
Semantic Scholar
Resistance of mice lacking the serum- and glucocorticoid-inducible kinase SGK1 against salt-sensitive hypertension induced by a high-fat diet.
D. Huang, K. Boini, H. Osswald, B. Friedrich +8 more
2006AJP - Renal Physiology71 citations
Semantic Scholar
Reevaluation of Fatty Acid Receptor 1 as a Drug Target for the Stimulation of Insulin Secretion in Humans
R. Wagner, G. Kaiser, F. Gerst, E. Christiansen +9 more
2013Diabetes70 citations Open access
Semantic Scholar
Discovery of TUG-770: A Highly Potent Free Fatty Acid Receptor 1 (FFA1/GPR40) Agonist for Treatment of Type 2 Diabetes
E. Christiansen, Steffen V. F. Hansen, Christian Urban, B. Hudson +11 more
2013ACS Medicinal Chemistry Letters69 citations Open access
Semantic Scholar
Overexpression of Kinase-Negative Protein Kinase Cδ in Pancreatic β-Cells Protects Mice From Diet-Induced Glucose Intolerance and β-Cell Dysfunction
A. Hennige, F. Ranta, I. Heinzelmann, M. Düfer +8 more
2009Diabetes66 citations Open access
Semantic Scholar
Enhanced insulin sensitivity of gene-targeted mice lacking functional KCNQ1.
K. Boini, D. Graf, A. Hennige, Saisudha Koka +11 more
2009American Journal of Physiology. Regulatory Integrative and Comparative Physiology64 citations Open access
Semantic Scholar
Fetuin-A influences vascular cell growth and production of proinflammatory and angiogenic proteins by human perivascular fat cells
D. Siegel-Axel, S. Ullrich, N. Stefan, K. Rittig +10 more
2014Diabetologia63 citations
Semantic Scholar
Conjugated Linoleic Acids Mediate Insulin Release through Islet G Protein-coupled Receptor FFA1/GPR40*
Johannes Schmidt, Kathrin Liebscher, Nicole Merten, Manuel Grundmann +9 more
2011Journal of Biological Chemistry62 citations Open access
Semantic Scholar
Identification of a potent and selective free fatty acid receptor 1 (FFA1/GPR40) agonist with favorable physicochemical and in vitro ADME properties.
E. Christiansen, Christian Urban, Manuel Grundmann, M. E. Due-Hansen +7 more
2011Journal of Medicinal Chemistry61 citations Open access
Semantic Scholar
Effects of IKs channel inhibitors in insulin-secreting INS-1 cells
S. Ullrich, Jiping Su, F. Ranta, O. Wittekindt +6 more
2005Pflügers Archiv59 citations
Semantic Scholar
Structure-Activity Study of Dihydrocinnamic Acids and Discovery of the Potent FFA1 (GPR40) Agonist TUG-469.
E. Christiansen, M. E. Due-Hansen, Christian Urban, Nicole Merten +13 more
2010ACS Medicinal Chemistry Letters58 citations Open access
Semantic Scholar
Pancreatic Steatosis Associates With Impaired Insulin Secretion in Genetically Predisposed Individuals
R. Wagner, B. Jaghutriz, F. Gerst, Morgana Barroso Oquendo +12 more
2020Journal of Clinical Endocrinology and Metabolism56 citations Open access
Semantic Scholar
The Expression of Aldolase B in Islets Is Negatively Associated With Insulin Secretion in Humans
F. Gerst, B. Jaghutriz, H. Staiger, A. Schulte +24 more
2018Journal of Clinical Endocrinology and Metabolism51 citations Open access
Semantic Scholar
Effects of I(Ks) channel inhibitors in insulin-secreting INS-1 cells.
S. Ullrich, Jiping Su, F. Ranta, O. Wittekindt +6 more
2005Pflügers Archiv: European Journal of Physiology51 citations
Semantic Scholar
The Akt inhibitor triciribine sensitizes prostate carcinoma cells to TRAIL‐induced apoptosis
Alexandra M. Dieterle, R. Orth, Merle Daubrawa, Antje Grotemeier +5 more
2009International Journal of Cancer47 citations Open access
Semantic Scholar
Serum- and Glucocorticoid-Inducible Kinase 1 Mediates Salt Sensitivity of Glucose Tolerance
K. Boini, A. Hennige, D. Huang, B. Friedrich +12 more
2006Diabetes45 citations Open access
Semantic Scholar
Epinephrine-induced hyperpolarization of islet cells without KATP channels.
A. Sieg, Jiping Su, A. Munoz, M. Buchenau +4 more
2004American Journal of Physiology. Endocrinology and Metabolism42 citations
Semantic Scholar
Protein kinase Cδ regulates nuclear export of FOXO1 through phosphorylation of the chaperone 14-3-3ζ
F. Gerst, G. Kaiser, M. Panse, T. Sartorius +7 more
2015Diabetologia38 citations Open access
Semantic Scholar
Activation of Extracellular Signal-Regulated Protein Kinases 1 and 2 (ERK1/2) by Free Fatty Acid Receptor 1 (FFAR1/GPR40) Protects from Palmitate-Induced Beta Cell Death, but Plays no Role in Insulin Secretion
M. Panse, F. Gerst, G. Kaiser, Charlott-Amélie Teutsch +4 more
2015Cellular Physiology and Biochemistry34 citations Open access
Semantic Scholar
Regulation of forkhead box O1 (FOXO1) by protein kinase B and glucocorticoids: different mechanisms of induction of beta cell death in vitro
G. Kaiser, F. Gerst, D. Michael, S. Berchtold +5 more
2013Diabetologia34 citations Open access
Semantic Scholar
The hepatokine fetuin-A disrupts functional maturation of pancreatic beta cells
F. Gerst, E. Kemter, E. Lorza-Gil, G. Kaiser +15 more
2021Diabetologia31 citations Open access
Semantic Scholar
Mice Lacking Free Fatty Acid Receptor 1 (GPR40/FFAR1) are Protected Against Conjugated Linoleic Acid-Induced Fatty Liver but Develop Inflammation and Insulin Resistance in the Brain
T. Sartorius, A. Drescher, M. Panse, P. Laštovička +5 more
2015Cellular Physiology and Biochemistry31 citations Open access
Semantic Scholar
IGF-1 Protects Against Dexamethasone-Induced Cell Death in Insulin Secreting INS-1 Cells Independent of AKT/PKB Phosphorylation
D. Avram, F. Ranta, A. Hennige, S. Berchtold +4 more
2008Cellular Physiology and Biochemistry29 citations Open access
Semantic Scholar
Untangling the interplay of genetic and metabolic influences on beta-cell function: Examples of potential therapeutic implications involving TCF7L2 and FFAR1
R. Wagner, H. Staiger, S. Ullrich, N. Stefan +2 more
2014Molecular Metabolism27 citations Open access
Semantic Scholar
Dexamethasone increases Na+/K+ ATPase activity in insulin secreting cells through SGK1.
S. Ullrich, Ying Zhang, D. Avram, F. Ranta +3 more
2007Biochemical and Biophysical Research Communications - BBRC27 citations
Semantic Scholar
The impact of genetic variation in the G6PC2 gene on insulin secretion depends on glycemia.
M. Heni, C. Ketterer, L. 't Hart, F. Ranta +18 more
2010Journal of Clinical Endocrinology and Metabolism26 citations
Semantic Scholar
Common polymorphisms within the NR4A3 locus, encoding the orphan nuclear receptor Nor-1, are associated with enhanced β-cell function in non-diabetic subjects
P. Weyrich, H. Staiger, A. Stančáková, S. Schäfer +10 more
2009BMC Medical Genetics26 citations Open access
Semantic Scholar
FFA2-, but not FFA3-agonists inhibit GSIS of human pseudoislets: a comparative study with mouse islets and rat INS-1E cells
E. Lorza-Gil, G. Kaiser, Elisabeth Rexen Ulven, G. König +7 more
2020Scientific Reports25 citations Open access
Semantic Scholar
Sunitinib specifically augments glucose-induced insulin secretion.
S. Lutz, Axel Ullrich, H. Häring, S. Ullrich +1 more
2017Cellular Signalling22 citations
Semantic Scholar
SGK1-Dependent Upregulation of Connective Tissue Growth Factor by Angiotensin II
A. Hussain, Amanda W. Wyatt, Ka-Na Wang, Madhuri Bhandaru +10 more
2008Kidney & Blood Pressure Research22 citations Open access
Semantic Scholar
Nor-1, a novel incretin-responsive regulator of insulin genes and insulin secretion.
A. Ordelheide, F. Gerst, O. Rothfuss, M. Heni +10 more
2013Molecular Metabolism21 citations Open access
Semantic Scholar
Glucose, adrenaline and palmitate antagonistically regulate insulin and glucagon secretion in human pseudoislets
E. Lorza-Gil, F. Gerst, M. B. Oquendo, U. Deschl +3 more
2019Scientific Reports20 citations Open access
Semantic Scholar
Palmitate and insulin counteract glucose-induced thioredoxin interacting protein (TXNIP) expression in insulin secreting cells via distinct mechanisms
M. Panse, O. Kluth, E. Lorza-Gil, G. Kaiser +5 more
2018PLoS ONE20 citations Open access
Semantic Scholar
Point mutation of Ffar1 abrogates fatty acid-dependent insulin secretion, but protects against HFD-induced glucose intolerance
S. Sabrautzki, G. Kaiser, Gerhard K. H. Przemeck, F. Gerst +8 more
2017Molecular Metabolism20 citations Open access
Semantic Scholar
Sphingomyelinase dependent apoptosis following treatment of pancreatic beta-cells with amyloid peptides Aß1-42 or IAPP
Ying Zhang, F. Ranta, Cai Tang, Ekaterina V. Shumilina +5 more
2009Apoptosis19 citations
Semantic Scholar
The KATP Channel is Critical for Calcium Sequestration into Non-ER Compartments in Mouse Pancreatic Beta Cells
M. Düfer, D. Haspel, P. Krippeit-Drews, M. Kelm +6 more
2006Cellular Physiology and Biochemistry19 citations
Semantic Scholar

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