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Hua Chen · SciRah

Researcher profile · Semantic Scholar

Hua Chen

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Hua Chen — researcher profile on SciRah

h-index: 29
Works: 45
Citations: 3,010

Most-cited papers

Central role of dysregulation of TGF-β/Smad in CKD progression and potential targets of its treatment.
Lin X. Chen, Tian Yang, D. Lu, Hui Zhao +5 more
2018Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie340 citations Open access
Semantic Scholar
Identification of serum metabolites associating with chronic kidney disease progression and anti-fibrotic effect of 5-methoxytryptophan
Dan-Qian Chen, Gang Cao, Hua Chen, C. Argyopoulos +24 more
2019Nature Communications252 citations Open access
Semantic Scholar
Metabolomics highlights pharmacological bioactivity and biochemical mechanism of traditional Chinese medicine.
Ming Wang, Lin X. Chen, Dan Liu, Hua Chen +2 more
2017Chemico-Biological Interactions193 citations
Semantic Scholar
Metabolomics insights into activated redox signaling and lipid metabolism dysfunction in chronic kidney disease progression
Hua Chen, Gang Cao, Dan-Qian Chen, Ming Wang +5 more
2016Redox Biology162 citations Open access
Semantic Scholar
Traditional uses, phytochemistry, pharmacology, toxicology and quality control of Alisma orientale (Sam.) Juzep: a review.
Ting Tian, Hua Chen, Ying-Yong Zhao
2014Journal of Ethnopharmacology154 citations
Semantic Scholar
Traditional uses, fermentation, phytochemistry and pharmacology of Phellinus linteus: A review.
Hua Chen, Ting Tian, Hua Miao, Ying-Yong Zhao
2016Fitoterapia134 citations
Semantic Scholar
Combined Clinical Phenotype and Lipidomic Analysis Reveals the Impact of Chronic Kidney Disease on Lipid Metabolism.
Hua Chen, Lin X. Chen, Dan Liu, Dan-Qian Chen +6 more
2017Journal of Proteome Research123 citations Open access
Semantic Scholar
The link between phenotype and fatty acid metabolism in advanced chronic kidney disease
Dan-Qian Chen, Hua Chen, Lin X. Chen, N. Vaziri +3 more
2017Nephrology, Dialysis and Transplantation108 citations Open access
Semantic Scholar
Unilateral ureteral obstruction causes gut microbial dysbiosis and metabolome disorders contributing to tubulointerstitial fibrosis
Lin X. Chen, Dan-Qian Chen, Jing-Ru Liu, Jun Zhang +6 more
2019Experimental and Molecular Medicine106 citations Open access
Semantic Scholar
Role of RAS/Wnt/β-catenin axis activation in the pathogenesis of podocyte injury and tubulo-interstitial nephropathy.
Lin X. Chen, Dan-Qian Chen, Ming Wang, Dan Liu +4 more
2017Chemico-Biological Interactions99 citations Open access
Semantic Scholar
Poricoic acid ZA, a novel RAS inhibitor, attenuates tubulo-interstitial fibrosis and podocyte injury by inhibiting TGF-β/Smad signaling pathway.
Ming Wang, Dan-Qian Chen, Minchang Wang, Hua Chen +4 more
2017Phytomedicine94 citations
Semantic Scholar
Lipidomics Biomarkers of Diet-Induced Hyperlipidemia and Its Treatment with Poria cocos.
Hua Miao, Yu-Hui Zhao, N. Vaziri, Dan-Dan Tang +6 more
2016Journal of Agricultural and Food Chemistry94 citations Open access
Semantic Scholar
Novel RAS inhibitor 25-O-methylalisol F attenuates epithelial-to-mesenchymal transition and tubulo-interstitial fibrosis by selectively inhibiting TGF-β-mediated Smad3 phosphorylation.
Hua Chen, Tian Yang, Minchang Wang, Dan-Qian Chen +2 more
2018Phytomedicine93 citations
Semantic Scholar
Diuretic activity of some fractions of the epidermis of Poria cocos.
Ya-Long Feng, P. Lei, Ting Tian, Lu Yin +5 more
2013Journal of Ethnopharmacology92 citations
Semantic Scholar
Metabolomic Signatures of Chronic Kidney Disease of Diverse Etiologies in the Rats and Humans.
Zhi-hao Zhang, Hua Chen, N. Vaziri, Jia-rong Mao +3 more
2016Journal of Proteome Research86 citations Open access
Semantic Scholar
Metabolomics in dyslipidemia.
Hua Chen, Hua Miao, Ya-Long Feng, Ying-Yong Zhao +1 more
2014Advances in Clinical Chemistry83 citations
Semantic Scholar
Metabolomic application in toxicity evaluation and toxicological biomarker identification of natural product.
Dan-Qian Chen, Hua Chen, Lin X. Chen, Dan-Dan Tang +2 more
2016Chemico-Biological Interactions81 citations
Semantic Scholar
Diuretic and anti-diuretic activities of fractions of Alismatis rhizoma.
Dan-Qian Chen, Ya-Long Feng, Ting Tian, Hua Chen +3 more
2014Journal of Ethnopharmacology74 citations
Semantic Scholar
Rhubarb Protect Against Tubulointerstitial Fibrosis by Inhibiting TGF-β/Smad Pathway and Improving Abnormal Metabolome in Chronic Kidney Disease
Zhi-hao Zhang, Ming-hua Li, Dan Liu, Hua Chen +4 more
2018Frontiers in Pharmacology69 citations Open access
Semantic Scholar
A Pharmaco-Metabonomic Study on Chronic Kidney Disease and Therapeutic Effect of Ergone by UPLC-QTOF/HDMS
Ying-Yong Zhao, Hua Chen, Ting Tian, Dan-Qian Chen +2 more
2014PLoS ONE69 citations Open access
Semantic Scholar
Diuretic and anti-diuretic activities of the ethanol and aqueous extracts of Alismatis rhizoma.
Ya-Long Feng, Hua Chen, Ting Tian, Dan-Qian Chen +2 more
2014Journal of Ethnopharmacology67 citations
Semantic Scholar
Urinary metabolomics and biomarkers of aristolochic acid nephrotoxicity by UPLC-QTOF/HDMS.
Ying-Yong Zhao, Dan-Dan Tang, Hua Chen, Jia-rong Mao +3 more
2015Bioanalysis59 citations
Semantic Scholar
An Integrated Lipidomics and Phenotype Study Reveals Protective Effect and Biochemical Mechanism of Traditionally Used Alisma orientale Juzepzuk in Chronic Kidney Disease
Fang Dou, Hua Miao, Jingwen Wang, Lin X. Chen +4 more
2018Frontiers in Pharmacology54 citations Open access
Semantic Scholar
Activated NF-κB/Nrf2 and Wnt/β-catenin pathways are associated with lipid metabolism in CKD patients with microalbuminuria and macroalbuminuria.
Ya-Long Feng, Hua Chen, Dan-Qian Chen, N. Vaziri +8 more
2019Biochimica et Biophysica Acta - Molecular Basis of Disease51 citations Open access
Semantic Scholar
Proteomics for Biomarker Identification and Clinical Application in Kidney Disease.
Lin X. Chen, Wei Su, Hua Chen, Dan-Qian Chen +3 more
2018Advances in Clinical Chemistry48 citations
Semantic Scholar
Alisol B 23-acetate attenuates CKD progression by regulating the renin–angiotensin system and gut–kidney axis
Hua Chen, Minchang Wang, Yuan-Yuan Chen, Lin X. Chen +4 more
2020Therapeutic Advances in Chronic Disease39 citations Open access
Semantic Scholar
Urinary Metabolomics on the Biochemical Profiles in Diet-Induced Hyperlipidemia Rat Using Ultraperformance Liquid Chromatography Coupled with Quadrupole Time-of-Flight SYNAPT High-Definition Mass Spectrometry
Hua Miao, Hua Chen, Xu Zhang, Lu Yin +4 more
2014Journal of Analytical Methods in Chemistry39 citations Open access
Semantic Scholar
Urinary biomarker and treatment mechanism of Rhizoma Alismatis on hyperlipidemia.
Hua Miao, Li Zhang, Dan-Qian Chen, Hua Chen +2 more
2017Biomedical chromotography37 citations
Semantic Scholar
Removal of uremic retention products by hemodialysis is coupled with indiscriminate loss of vital metabolites.
Zhi-hao Zhang, Jia-rong Mao, Hua Chen, Wei Su +5 more
2017Clinical Biochemistry36 citations Open access
Semantic Scholar
Urine metabolomics reveals new insights into hyperlipidemia and the therapeutic effect of rhubarb
Hua Chen, Bin Yuan, Hua Miao, Y. Tan +3 more
201525 citations
Semantic Scholar
Plasma lipidomics reveal profound perturbation of glycerophospholipids, fatty acids, and sphingolipids in diet-induced hyperlipidemia.
Hua Miao, Hua Chen, Song-Wen Pei, Xu Bai +2 more
2015Chemico-Biological Interactions18 citations Open access
Semantic Scholar
Metabolomics Reveals Hyperlipidemic Biomarkers and Antihyperlipidemic Effect of Poria cocos
Hua Chen, Lin X. Chen, Dan-Dan Tang, Dan-Qian Chen +3 more
201615 citations
Semantic Scholar
Title Role of RAS / Wnt / beta-catenin axis activation in the pathogenesis of podocyte injury and tubulo-interstitial nephropathy
Lin X. Chen, Dan-Qian Chen, Ming Wang, Dan Liu +4 more
20178 citations
Semantic Scholar
[Research progress on pharmacology, pharmacokinetics and determination of ergosta-4,6,8 (14),22-tetraen-3-one].
Han Chen, Dan-Qian Chen, Quanqaun Li, Peng-fei Li +2 more
2014Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica5 citations
Semantic Scholar
Gene and protein expressions and metabolomics exhibit activated redox signaling and wnt/β-catenin pathway are associated with metabolite dysfunction in patients with chronic kidney disease
Dan-Qian Chen, Gang Cao, Hua Chen, Dan Liu +7 more
2017Redox Biology3 citations Open access
Semantic Scholar
Diuretic activity in rats: the ethanol and aqueous extracts of rhubarb (657.1)
Lu Yin, Ya-Long Feng, Ting Tian, Hua Chen +2 more
20142 citations
Semantic Scholar
Title The link between phenotype and fatty acid metabolism in advanced chronic kidney disease Permalink
Dan-Qian Chen, Hua Chen, Lin X. Chen, N. Vaziri +3 more
20170 citations
Semantic Scholar
Role of RAS/Wnt/ b -catenin axis activation in the pathogenesis of podocyte injury and tubulo-interstitial nephropathy Chemico-Biological Interactions
Lin X. Chen, Dan-Qian Chen, Ming Wang, Dan Liu +4 more
20170 citations
Semantic Scholar
脂質の高脂血症に関する研究の進展【JST・京大機械翻訳】
Hua Chen, Lin X. Chen, Nan Zhang, Hua Miao +1 more
20160 citations
Semantic Scholar
漢方薬による腎臓疾患の治療と漢方薬の毒性研究におけるメタボロミクスの応用と進展【JST・京大機械翻訳】
Lin X. Chen, Dan-Qian Chen, Hui Zhao, Feng-Lin Lu +2 more
20160 citations
Semantic Scholar
Application and progress of metabolomics in nephropathy treatment with traditional Chinese medicine and related toxicity study
Lin X. Chen, Dan-Qian Chen, Hui Zhao, Feng-Lin Lu +2 more
20160 citations
Semantic Scholar
Lipidomics Biomarkers of Diet-Induced Hyperlipidemia and Its Treatment with cocos.
Hua Miao, Yu-Hui Zhao, N. Vaziri, Dan-Dan Tang +7 more
20160 citations
Semantic Scholar
A pharmaco-metabolomic study of chronic aristolochic acid nephropathy
Ying-Yong Zhao, Shun-Min Liu, Hua Chen, Ya-Long Feng +3 more
20140 citations
Semantic Scholar
Histological findings of hematoxylin-eosin and picro-sirius red staining as well as ED-1 and TGF-β1 immunohistochemisrty.
Ying-Yong Zhao, Hua Chen, Ting Tian, Dan-Qian Chen +2 more
20140 citations Open access
Semantic Scholar
Study on extraction technology of polysaccharides from coconut inflorescence sap
Hua Chen
20090 citations
Semantic Scholar

Frequent co-authors

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Ying-Yong Zhao×41
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Ying-Yong Zhao — researcher profile on SciRah
Dan-Qian Chen×30
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Dan-Qian Chen — researcher profile on SciRah
Lin X. Chen×19
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Lin X. Chen — researcher profile on SciRah
N. Vaziri×17
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N. Vaziri — researcher profile on SciRah

×12

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Hua Miao — researcher profile on SciRah

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Ming Wang — researcher profile on SciRah

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Xu Bai — researcher profile on SciRah

Ya-Long Feng×9

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Ya-Long Feng — researcher profile on SciRah

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Dan Liu — researcher profile on SciRah

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Ting Tian — researcher profile on SciRah

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Li Zhang — researcher profile on SciRah

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Wei Su — researcher profile on SciRah