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B. Freie · SciRah

Researcher profile · Semantic Scholar

B. Freie

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B. Freie — researcher profile on SciRah

h-index: 17
Works: 39
Citations: 1,119

Most-cited papers

The MYC transcription factor network: balancing metabolism, proliferation and oncogenesis
P. Carroll, B. Freie, Haritha Mathsyaraja, R. Eisenman
2018Frontiers in Medicine249 citations Open access
Semantic Scholar
Fanconi anemia type C and p53 cooperate in apoptosis and tumorigenesis.
Laurel D. Schantz, Laura S. Haneline, A. Orazi, H. Broxmeyer +8 more
2003Blood89 citations
Semantic Scholar
Oxidative Stress/Damage Induces Multimerization and Interaction of Fanconi Anemia Proteins*
Su-Jung Park, Samantha L. M. Ciccone, B. D. Beck, B. Hwang +3 more
2004Journal of Biological Chemistry78 citations Open access
Semantic Scholar
Ex vivo culture of Fancc-/- stem/progenitor cells predisposes cells to undergo apoptosis, and surviving stem/progenitor cells display cytogenetic abnormalities and an increased risk of malignancy.
Xia-Xin Li, M. L. Le Beau, Samantha L. M. Ciccone, Feng-Chun Yang +7 more
2005Blood72 citations Open access
Semantic Scholar
MAX functions as a tumor suppressor and rewires metabolism in small cell lung cancer
A. Augert, Haritha Mathsyaraja, A. Ibrahim, B. Freie +10 more
2020Cancer Cell66 citations Open access
Semantic Scholar
Continuous in vivo infusion of interferon-gamma (IFN-gamma) preferentially reduces myeloid progenitor numbers and enhances engraftment of syngeneic wild-type cells in Fancc-/- mice.
Xia-Xin Li, Yanzhu Yang, Jin Yuan, P. Hong +4 more
2004Blood63 citations Open access
Semantic Scholar
Molecular evidence that in situ-transduced fetal liver hematopoietic stem/progenitor cells give rise to medullary hematopoiesis in adult rats.
D. Clapp, B. Freie, Wei-Hua Lee, You-Yan Zhang
1995Blood63 citations
Semantic Scholar
A point mutation in the murine Hem1 gene reveals an essential role for Hematopoietic Protein 1 in lymphopoiesis and innate immunity
Heon Park, K. Staehling-Hampton, M. Appleby, M. Brunkow +10 more
2008Journal of Experimental Medicine60 citations Open access
Semantic Scholar
Max deletion destabilizes MYC protein and abrogates Eµ-Myc lymphomagenesis
Haritha Mathsyaraja, B. Freie, Pei-Feng Cheng, E. Babaeva +4 more
2019Genes & Development50 citations Open access
Semantic Scholar
A Role for the Fanconi Anemia C Protein in Maintaining the DNA Damage-induced G2 Checkpoint*
B. Freie, Samantha L. M. Ciccone, Xia-Xin Li, P. Plett +6 more
2004Journal of Biological Chemistry46 citations Open access
Semantic Scholar
Myeloproliferative sarcoma virus directed expression of beta-galactosidase following retroviral transduction of murine hematopoietic cells.
D. Clapp, B. Freie, E. Srour, M. Yoder +2 more
1995Experimental Hematology41 citations
Semantic Scholar
Fanconi anemia type C-deficient hematopoietic stem/progenitor cells exhibit aberrant cell cycle control.
Xia-Xin Li, P. Plett, Yanzhu Yang, P. Hong +5 more
2003Blood38 citations Open access
Semantic Scholar
A Positive Role for the Ku Complex in DNA Replication Following Strand Break Damage in Mammals*
Su-Jung Park, Samantha L. M. Ciccone, B. Freie, A. Kurimasa +4 more
2004Journal of Biological Chemistry37 citations Open access
Semantic Scholar
Loss of MGA repression mediated by an atypical polycomb complex promotes tumor progression and invasiveness
Haritha Mathsyaraja, Jonathen Catchpole, B. Freie, Emily Eastwood +15 more
2021eLife31 citations Open access
Semantic Scholar
CD34 stem/progenitor cells purified from cryopreserved normal cord blood can be transduced with high efficiency by a retroviral vector and expanded ex vivo with stable integration and expression of Fanconi anemia complementation C gene.
Li Lu, Y. Ge, Zhi-hua Li, B. Freie +2 more
1995Cell Transplantation24 citations
Semantic Scholar
The glucose-sensing transcription factor MLX balances metabolism and stress to suppress apoptosis and maintain spermatogenesis
P. Carroll, B. Freie, Pei-Feng Cheng, Sivakanthan Kasinathan +11 more
2021PLoS Biology22 citations Open access
Semantic Scholar
The Drosophila S3 multifunctional DNA repair/ribosomal protein protects Fanconi anemia cells against oxidative DNA damaging agents.
Mark R. Kelley, Renee Tritt, Yi Xu, Sheri New +3 more
2001Mutation research20 citations
Semantic Scholar
Correction of Fanconi anemia type C phenotypic abnormalities using a clinically suitable retroviral vector infection protocol.
B. Freie, Parmesh Dutt, D. Clapp
1996Cell Transplantation13 citations Open access
Semantic Scholar
Ratcheting Myc
B. Freie, R. Eisenman
2008Cancer Cell11 citations Open access
Semantic Scholar
Variation in long-term engraftment of a large consecutive series of lambs transplanted in utero with human hematopoietic cells.
Jonathan Bernstein, D. Boyle, E. Srour, Ryan J. Cooper +4 more
1997Biology of Blood and Marrow Transplantation11 citations
Semantic Scholar
MAX inactivation deregulates the MYC network and induces neuroendocrine neoplasia in multiple tissues
B. Freie, Ali H. Ibrahim, Patrick A. Carroll, R. T. Bronson +3 more
2024bioRxiv5 citations Open access
Semantic Scholar
A germline point mutation in the MYC-FBW7 phosphodegron initiates hematopoietic malignancies
B. Freie, Patrick A. Carroll, Barbara J. Varnum-Finney, Erin L. Ramsey +3 more
2024Genes & Development5 citations Open access
Semantic Scholar
Loss of MGA mediated Polycomb repression promotes tumor progression and invasiveness
Haritha Mathsyaraja, Jonathen Catchpole, Emily Eastwood, E. Babaeva +13 more
2020bioRxiv5 citations Open access
Semantic Scholar
MAX inactivation deregulates the MYC network and induces neuroendocrine neoplasia in multiple tissues
B. Freie, Ali H. Ibrahim, Patrick A. Carroll, R. Bronson +3 more
2025Science Advances4 citations Open access
Semantic Scholar
Oligonucleotide purification in milligram quantities.
B. Freie, S. Larsen
1991BioTechniques4 citations
Semantic Scholar
MondoA mediates transcriptional coordination between the MYC network and the integrated stress response in pancreatic cancer
Erin L. Ramsey, S. Dobersch, B. Freie, Nan Hyung Hong +4 more
2026Proceedings of the National Academy of Sciences of the United States of America2 citations Open access
Semantic Scholar
A Germline Point Mutation in the MYC-FBW7 Phosphodegron Initiates Hematopoietic Malignancies
B. Freie, Patrick A. Carroll, Barbara J. Varnum-Finney, Vijay Ramani +2 more
2023bioRxiv2 citations Open access
Semantic Scholar
MLX balances metabolism and stress to suppress apoptosis and maintain spermatogenesis
P. Carroll, Pei-Feng Cheng, B. Freie, Sivakanthan Kasinathan +10 more
2020bioRxiv2 citations Open access
Semantic Scholar
Fanconi anemia type C and p 53 cooperate in apoptosis and tumorigenesis
Laurel D. Schantz, Laura S. Haneline, A. Orazi, H. Broxmeyer +8 more
20032 citations
Semantic Scholar
Correction of Fanconi Anemia Type C Phenotypic Abnormalities Using a Clinically Suitable Retroviral Vector Infection Protocol
B. Freie, P. Dutt, D. Clapp
19962 citations Open access
Semantic Scholar
MondoA mediates transcriptional coordination between the MYC network and the integrated stress response in pancreatic ductal adenocarcinoma
Erin L. Ramsey, S. Dobersch, B. Freie, Nan Hyung Hong +4 more
2025bioRxiv1 citations Open access
Semantic Scholar
Continuous in vivo infusion of interferon-gamma (IFN- (cid:1) ) preferentially reduces myeloid progenitor numbers and enhances engraftment of syngeneic wild-type cells in Fancc (cid:2) / (cid:2) mice
Xia-Xin Li, Yanzhu Yang, P. Hong, B. Freie +3 more
20041 citations
Semantic Scholar
CD34+++ STEM/PROGENITOR CELLS PURIFIED FROM CRYOPRESERVED NORMAL CORD BLOOD CAN BE TRANSDUCED WITH HIGH EFFICIENCY BY A RETROVIRAL VECTOR AND EXPANDED EX VIVO WITH STABLE INTEGRATION AND EXPRESSION OF FANCONI ANEMIA COMPLEMENTATION C GENE.
Li Lu, Y. Ge, Zhi-hua Li, B. Freie +2 more
1995Cell Transplantation1 citations Open access
Semantic Scholar
Corrigendum: A germline point mutation in the MYC-FBW7 phosphodegron initiates hematopoietic malignancies
B. Freie, Patrick A. Carroll, Barbara J. Varnum-Finney, Erin L. Ramsey +3 more
2025Genes & Development0 citations Open access
Semantic Scholar
Author response: Loss of MGA repression mediated by an atypical polycomb complex promotes tumor progression and invasiveness
Haritha Mathsyaraja, Jonathen Catchpole, B. Freie, Emily Eastwood +15 more
20210 citations Open access
Semantic Scholar
Max deletion destabilizes MYC protein and abrogates Eμ-Myc lymphomagenesis
Haritha Mathsyaraja, B. Freie, Pei-Feng Cheng, E. Babaeva +3 more
2019bioRxiv0 citations Open access
Semantic Scholar
Hem-1 is essential for hematopoietic cell development and function by regulating the actin cytoskeleton (138.8)
Heon Park, K. Staehling-Hampton, M. Appleby, M. Brunkow +9 more
2009Journal of Immunology0 citations
Semantic Scholar
The fanconi anemia complementation group c protein is required for normal cell cycle arrest induced by ionizing irradiation
B. Freie, Samantha L. M. Ciccone, Kathy Nawa, Suk-hee Lee +1 more
20000 citations
Semantic Scholar
Engraftmnt and proliferation of retroviral transduced human hematopoietic progenitor/stem cells in featl sheep
B. Freie, C. Fink, D. Boyle, D. Srour +2 more
19970 citations
Semantic Scholar

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Patrick A. Carroll×7

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Laura S. Haneline×6

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Robert N. Eisenman×6

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