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R. Woestenborghs · SciRah

Researcher profile · Semantic Scholar

R. Woestenborghs

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R. Woestenborghs — researcher profile on SciRah

h-index: 42
Works: 126
Citations: 6,485

Most-cited papers

Potent and selective inhibition of HIV-1 replication in vitro by a novel series of TIBO derivatives
R. Pauwels, K. Andries, J. Desmyter, D. Schols +10 more
1990Nature675 citations
Semantic Scholar
The Clinical Pharmacokinetics of Itraconazole: An Overview
J. Heykants, A. van Peer, V. V. D. Van de Velde, P. V. van Rooy +5 more
1989Mycoses (Berlin)393 citations
Semantic Scholar
Pharmacokinetics of the novel antipsychotic agent risperidone and the prolactin response in healthy subjects
May‐Lynn Huang, A. van Peer, R. Woestenborghs, R. de Coster +5 more
1993Clinical pharmacology and therapy332 citations
Semantic Scholar
Pharmacokinetics of itraconazole following oral administration to normal volunteers
T. Hardin, J. Graybill, R. Fetchick, R. Woestenborghs +2 more
1988Antimicrobial Agents and Chemotherapy304 citations Open access
Semantic Scholar
Phase I and pharmacokinetic study of farnesyl protein transferase inhibitor R115777 in advanced cancer.
J. Zujewski, I. Horak, C. Bol, R. Woestenborghs +16 more
2000Journal of Clinical Oncology279 citations
Semantic Scholar
Absorption, metabolism, and excretion of risperidone in humans.
G. Mannens, May‐Lynn Huang, W. Meuldermans, J. Hendrickx +2 more
1993Drug Metabolism And Disposition266 citations
Semantic Scholar
Pharmacokinetic profile of orally administered itraconazole in human skin.
G. Cauwenbergh, H. Degreef, J. Heykants, R. Woestenborghs +2 more
1988Journal of American Academy of Dermatology240 citations
Semantic Scholar
Linearity of Pharmacokinetics and Model Estimation of Sufentanil
E. Gepts, S. Shafer, F. Camu, D. Stanski +3 more
1995Anesthesiology198 citations
Semantic Scholar
Potent and highly selective human immunodeficiency virus type 1 (HIV-1) inhibition by a series of alpha-anilinophenylacetamide derivatives targeted at HIV-1 reverse transcriptase.
R. Pauwels, K. Andries, Z. Debyser, P. V. Van Daele +6 more
1993Proceedings of the National Academy of Sciences of the United States of America161 citations Open access
Semantic Scholar
Antifungal pulse therapy for onychomycosis. A pharmacokinetic and pharmacodynamic investigation of monthly cycles of 1-week pulse therapy with itraconazole.
P. De Doncker, J. Decroix, Ǵ. Píerard, Dirk Roelant +6 more
1996Archives of Dermatology159 citations
Semantic Scholar
Posttreatment itraconazole levels in the nail. New implications for treatment in onychomycosis.
M. Willemsen, P. De Doncker, J. Willems, R. Woestenborghs +5 more
1992Journal of American Academy of Dermatology157 citations
Semantic Scholar
The pharmacokinetics of itraconazole in animals and man: an overview
J. Heykants, M. Michiels, W. Meuldermans, J. Monbaliu +5 more
1987135 citations
Semantic Scholar
Effect of Food on the Pharmacokinetics of a New Hydroxypropyl‐β‐Cyclodextrin Formulation of Itraconazole
V. V. D. Van de Velde, A. van Peer, J. Heykants, R. Woestenborghs +3 more
1996Pharmacotherapy124 citations
Semantic Scholar
The pharmacokinetics of risperidone in humans: a summary.
J. Heykants, M.-L. Huang, G. Mannens, W. Meuldermans +4 more
1994Journal of Clinical Psychiatry123 citations
Semantic Scholar
The CSF and plasma pharmacokinetics of sufentanil after intrathecal administration.
V. Hansdottir, T. Hedner, R. Woestenborghs, Gunnar Nordberg
1991Anesthesiology121 citations Open access
Semantic Scholar
The effects of food and dose on the oral systemic availability of itraconazole in healthy subjects
A. van Peer, R. Woestenborghs, J. Heykants, R. Gasparini +1 more
2004European Journal of Clinical Pharmacology117 citations
Semantic Scholar
Itraconazole penetrates the nail via the nail matrix and the nail bed—an investigation in onychomycosis
L. Matthieu, P. Doncker, G. Cauwenbergh, R. Woestenborghs +3 more
1991Clincal and Experimental Dermatology113 citations
Semantic Scholar
The orally administered P-glycoprotein inhibitor R101933 does not alter the plasma pharmacokinetics of docetaxel.
L. van Zuylen, A. Sparreboom, A. van der Gaast, M. V. D. van der Burg +5 more
2000Clinical Cancer Research100 citations
Semantic Scholar
Determination of cisapride in plasma and animal tissues by high-performance liquid chromatography.
R. Woestenborghs, W. Lorreyne, F. van Rompaey, J. Heykants
1988Journal of Chromatography A97 citations
Semantic Scholar
Influence of age, renal and liver impairment on the pharmacokinetics of risperidone in man
E. Snoeck, A. van Peer, M. Sack, M. Horton +4 more
1995Psychopharmacology88 citations
Semantic Scholar
Discrepancies in bioassay and chromatography determinations explained by metabolism of itraconazole to hydroxyitraconazole: studies of interpatient variations in concentrations
J. Hostetler, J. Heykants, K. Clemons, R. Woestenborghs +2 more
1993Antimicrobial Agents and Chemotherapy85 citations Open access
Semantic Scholar
Concentrations in plasma and safety of 7 days of intravenous itraconazole followed by 2 weeks of oral itraconazole solution in patients in intensive care units
K. Vandewoude, D. Vogelaers, J. Decruyenaere, P. Jaqmin +5 more
1997Antimicrobial Agents and Chemotherapy80 citations Open access
Semantic Scholar
The pharmacokinetics of oral itraconazole in AIDS patients
D. Smith, V. Velde, R. Woestenborghs, B. Gazzard
1992The Journal of pharmacy and pharmacology78 citations
Semantic Scholar
Pharmacokinetic study and cardiovascular monitoring of nebivolol in normal and obese subjects
G. Cheymol, R. Woestenborghs, E. Snoeck, R. Ianucci +4 more
1997European Journal of Clinical Pharmacology66 citations
Semantic Scholar
Alfentanil Pharmacokinetics and Metabolism in Humans
W. Meuldermans, A. van Peer, J. Hendrickx, R. Woestenborghs +5 more
1988Anesthesiology64 citations Open access
Semantic Scholar
Itraconazole pharmacokinetics in patients with renal dysfunction
J. Boelaert, M. Schurgers, E. Matthys, R. Daneels +4 more
1988Antimicrobial Agents and Chemotherapy63 citations Open access
Semantic Scholar
A Pharmacokinetic Study of Intravenous Itraconazole Followed by Oral Administration of Itraconazole Capsules in Patients with Advanced Human Immunodeficiency Virus Infection
Hong-Hui Zhou, Mitchell Goldman, Jane Wu, R. Woestenborghs +6 more
1998Journal of clinical pharmacology56 citations
Semantic Scholar
Reduction of the prodrug loperamide oxide to its active drug loperamide in the gut of rats, dogs, and humans.
K. Lavrijsen, D. V. van Dyck, J. V. van Houdt, J. Hendrickx +4 more
1995Drug Metabolism And Disposition56 citations
Semantic Scholar
New tetrahydroimidazo[4,5,1-jk][1,4]-benzodiazepin-2(1H)-one and -thione derivatives are potent inhibitors of human immunodeficiency virus type 1 replication and are synergistic with 2',3'-dideoxynucleoside analogs
R. Pauwels, K. Andries, Z. Debyser, M. Kukla +6 more
1994Antimicrobial Agents and Chemotherapy55 citations Open access
Semantic Scholar
Excretion and biotransformation of cisapride in dogs and humans after oral administration.
W. Meuldermans, A. van Peer, J. Hendrickx, W. Lauwers +4 more
1988Drug Metabolism And Disposition55 citations
Semantic Scholar
The Pharmacokinetics of Continuous Epidural Sufentanil and Bupivacaine Infusion After Thoracotomy
V. Hansdottir, R. Woestenborghs, G. Nordberg
1996Anesthesia and Analgesia53 citations Open access
Semantic Scholar
Determination of risperidone and 9-hydroxyrisperidone in plasma, urine and animal tissues by high-performance liquid chromatography.
R. Woestenborghs, W. Lorreyne, Frank Van Rompaey, J. Heykants
1992Journal of Chromatography A51 citations
Semantic Scholar
Assay methods for fentanyl in serum: gas-liquid chromatography versus radioimmunoassay.
R. Woestenborghs, D. Stanski, James C. Scott, J. Heykants
1987Anesthesiology50 citations Open access
Semantic Scholar
The Cerebrospinal Fluid and Plasma Pharmacokinetics of Sufentanil After Thoracic or Lumbar Epidural Administration
V. Hansdottir, R. Woestenborghs, G. Nordberg
1995Anesthesia and Analgesia48 citations Open access
Semantic Scholar
Clinical Pharmacokinetics of Nebivolol
A. Peer, E. Snoeck, R. Woestenborghs, V. Velde +3 more
199145 citations
Semantic Scholar
Stimulation by risperidone of rat prolactin secretion in vivo and in cultured pituitary cells in vitro.
C. Bowden, S. Voina, R. Woestenborghs, R. de Coster +1 more
1992Journal of Pharmacology and Experimental Therapeutics43 citations
Semantic Scholar
Down regulation of serotonin-S2 receptor sites in rat brain by chronic treatment with the serotonin-S2 antagonists: ritanserin and setoperone
J. Leysen, P. V. Van Gompel, W. Gommeren, R. Woestenborghs +1 more
2004Psychopharmacology38 citations
Semantic Scholar
Influence of itraconazole on the pharmacokinetics and electrocardiographic effects of astemizole.
Romain Lefebvre, A. van Peer, R. Woestenborghs
2003British Journal of Clinical Pharmacology35 citations Open access
Semantic Scholar
Assay Methods for Sufentanil in Plasma: Radioimmunoassay Versus Gas Chromatography‐Mass Spectrometry
R. Woestenborghs, Philippe Timmerman, M. Cornelissen, Frank A. M. B. S. Van Rompaey +4 more
1994Anesthesiology29 citations
Semantic Scholar
Protein binding of the analgesics alfentanil and sufentanil in maternal and neonatal plasma
W. Meuldermans, R. Woestenborghs, Henk Noorduin, Frederic Camu +2 more
2004European Journal of Clinical Pharmacology27 citations
Semantic Scholar
Pharmacokinetics of oral antifungals and their clinical implications.
J. Heykants, A. van Peer, K. Lavrijsen, W. Meuldermans +2 more
1990British journal of clinical practice. Supplement27 citations
Semantic Scholar
Pharmacokinetics of ketanserin and its metabolite ketanserin-ol in man after intravenous, intramuscular and oral administration
J. Heykants, A. van Peer, R. Woestenborghs, S. Gould +1 more
2004European Journal of Clinical Pharmacology26 citations
Semantic Scholar
Excretion and biotransformation of alfentanil and sufentanil in rats and dogs.
W. Meuldermans, J. Hendrickx, W. Lauwers, R. Hurkmans +5 more
1987Drug Metabolism And Disposition26 citations
Semantic Scholar
Pharmacokinetics and tissue distribution of the new gastrokinetic agent cisapride in rat, rabbit and dog.
M. Michiels, J. Monbaliu, R. Hendriks, R. Geerts +2 more
1987Arzneimittel-Forschung24 citations
Semantic Scholar
Inhibition of pancreaticobiliary secretion by loperamide in humans
P. Thimister, W. Hopman, R. F. C. Van Roermund, H. Willems +3 more
1997Hepatology22 citations Open access
Semantic Scholar
Pharmacokinetics and tissue distribution of ketanserin in rat, rabbit and dog.
M. Michiels, J. Monbaliu, W. Meuldermans, R. Hendriks +3 more
1988Arzneimittel-Forschung20 citations
Semantic Scholar
Bioassays for itraconazole blood levels: an interlaboratory collaborative study.
F. C. Odds, B. Dupont, M. G. Rinaldi, D. A. Stevens +2 more
1999Journal of Antimicrobial Chemotherapy18 citations
Semantic Scholar
Risperidone: Effects of Formulations on Oral Bioavailability
R. Gutiérrez, Peter I. D. Lee, May‐Lynn Huang, R. Woestenborghs
1997Pharmacotherapy18 citations
Semantic Scholar
The Pharmacokinetic Properties of Topical Levocabastine
J. Heykants, A. van Peer, V. V. D. Van de Velde, E. Snoeck +2 more
1995Clinical Pharmacokinetics18 citations
Semantic Scholar
Pharmacokinetics of alfentanil during and after a fixed rate infusion.
H. V. van Beem, A. van Peer, R. Gasparini, R. Woestenborghs +4 more
1989British Journal of Anaesthesia18 citations Open access
Semantic Scholar

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J. Heykants×17
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J. Heykants — researcher profile on SciRah
A. van Peer×15
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A. van Peer — researcher profile on SciRah
W. Meuldermans×13
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W. Meuldermans — researcher profile on SciRah
J. Heykants×7
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J. Heykants — researcher profile on SciRah

×7

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J. Heykants — researcher profile on SciRah

G. Cauwenbergh×6

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G. Cauwenbergh — researcher profile on SciRah

J. Hendrickx×5

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J. Hendrickx — researcher profile on SciRah

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E. Snoeck — researcher profile on SciRah

V. V. D. Van de Velde×4

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V. V. D. Van de Velde — researcher profile on SciRah

K. Lavrijsen×4

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K. Lavrijsen — researcher profile on SciRah

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G. Mannens — researcher profile on SciRah

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R. Pauwels — researcher profile on SciRah