Researcher profile · Semantic Scholar

C. Drysdale

h-index: 12
Works: 21
Citations: 474

Most-cited papers

The Gcn4p Activation Domain Interacts Specifically In Vitro with RNA Polymerase II Holoenzyme, TFIID, and the Adap-Gcn5p Coactivator Complex
C. Drysdale, B. M. Jackson, R. McVeigh, E. Klebanow +6 more
1998Molecular and Cellular Biology108 citations Open access
Semantic Scholar
BCL11A enhancer edited hematopoietic stem cells persist in rhesus monkeys without toxicity.
Selami Demirci, Jing Zeng, Yuxuan Wu, N. Uchida +23 more
2020Journal of Clinical Investigation54 citations Open access
Semantic Scholar
Cas9 protein delivery non-integrating lentiviral vectors for gene correction in sickle cell disease
N. Uchida, C. Drysdale, Tina Nassehi, Jackson Gamer +8 more
2021Molecular Therapy: Methods & Clinical Development51 citations Open access
Semantic Scholar
High-Efficiency Lentiviral Transduction of Human CD34+ Cells in High-Density Culture with Poloxamer and Prostaglandin E2
N. Uchida, Tina Nassehi, C. Drysdale, Jackson Gamer +6 more
2019Molecular Therapy: Methods & Clinical Development38 citations Open access
Semantic Scholar
Hematopoietic-Stem-Cell-Targeted Gene-Addition and Gene-Editing Strategies for β-hemoglobinopathies.
C. Drysdale, Tina Nassehi, Jackson Gamer, Morgan Yapundich +2 more
2021Cell Stem Cell29 citations Open access
Semantic Scholar
Busulfan Combined with Immunosuppression Allows Efficient Engraftment of Gene-Modified Cells in a Rhesus Macaque Model.
N. Uchida, Tina Nassehi, C. Drysdale, Jackson Gamer +9 more
2019Molecular Therapy29 citations Open access
Semantic Scholar
Low-Dose Busulfan Reduces Human CD34+ Cell Doses Required for Engraftment in c-kit Mutant Immunodeficient Mice
Alexis Leonard, Morgan Yapundich, Tina Nassehi, Jackson Gamer +6 more
2019Molecular Therapy: Methods & Clinical Development28 citations Open access
Semantic Scholar
Preclinical evaluation for engraftment of CD34+ cells gene-edited at the sickle cell disease locus in xenograft mouse and non-human primate models
N. Uchida, Lin-Hong Li, Tina Nassehi, C. Drysdale +14 more
2021Cell Reports Medicine27 citations Open access
Semantic Scholar
Definitive hematopoietic stem/progenitor cells from human embryonic stem cells through serum/feeder-free organoid-induced differentiation
Selami Demirci, J. Haro-Mora, Alexis Leonard, C. Drysdale +8 more
2020Stem cell research & therapeutics25 citations Open access
Semantic Scholar
βT87Q-Globin Gene Therapy Reduces Sickle Hemoglobin Production, Allowing for Ex Vivo Anti-sickling Activity in Human Erythroid Cells
Selami Demirci, Bjorg Gudmundsdottir, Quan Li, J. Haro-Mora +7 more
2020Molecular Therapy: Methods & Clinical Development24 citations Open access
Semantic Scholar
Immunoresponse to Gene-Modified Hematopoietic Stem Cells
C. Drysdale, J. Tisdale, N. Uchida
2019Molecular Therapy: Methods & Clinical Development24 citations Open access
Semantic Scholar
Sustained fetal hemoglobin induction in vivo is achieved by BCL11A interference and coexpressed truncated erythropoietin receptor
N. Uchida, F. Ferrara, C. Drysdale, Morgan Yapundich +16 more
2021Science Translational Medicine13 citations
Semantic Scholar
Durable and Robust Fetal Globin Induction without Anemia in Rhesus Monkeys Following Autologous Hematopoietic Stem Cell Transplant with BCL11A Erythroid Enhancer Editing
Selami Demirci, Jing Zeng, Yuxuan Wu, N. Uchida +18 more
2019Blood6 citations Open access
Semantic Scholar
Ex vivo immunological evaluation of stable mixed chimeric patients after matched related donor allogeneic transplantation in sickle cell disease.
Lydia N. Raines, Matthew M. Hsieh, Tina Nassehi, C. Drysdale +2 more
2019Cytotherapy5 citations
Semantic Scholar
Truncated Erythropoietin Receptors Confer an In Vivo Selective Advantage in Gene-Modified Erythroid Cells Expressing Fetal Hemoglobin Due to BCL11A Interference
N. Uchida, C. Drysdale, Morgan Yapundich, Jackson Gamer +11 more
2019Blood5 citations Open access
Semantic Scholar
Fetal hemoglobin and F-cell variance in mobilized CD34+ cell-transplanted rhesus monkeys
Selami Demirci, Juan J. Haro Mora, Morgan Yapundich, C. Drysdale +8 more
2019Experimental Hematology3 citations Open access
Semantic Scholar
Preclinical Evaluation for Engraftment of Gene-Edited CD34+ Cells with a Sickle Cell Disease Mutation in a Rhesus Transplantation Model
N. Uchida, Lin-Hong Li, Tina Nassehi, Morgan Yapundich +13 more
2019Blood2 citations Open access
Semantic Scholar
Development of a Clinically Applicable Method for High-Efficiency Gene Correction of Plerixafor-Mobilized CD34+ Cells from Patients with Sickle Cell Disease
N. Uchida, Lin-Hong Li, J. Haro-Mora, Selami Demirci +9 more
2018Blood2 citations Open access
Semantic Scholar
COMBINING CHEMISTRY AND ARTISTRY: SYNTHESIS AND IDENTIFICATION OF ARTISTIC COPPER PATINAS USING RAMAN SPECTROSCOPY
C. Drysdale
20141 citations
Semantic Scholar
Correction to: Definitive hematopoietic stem/progenitor cells from human embryonic stem cells through serum/feeder-free organoid-induced differentiation
Selami Demirci, J. Haro-Mora, Alexis Leonard, C. Drysdale +8 more
2020Stem cell research & therapeutics0 citations Open access
Semantic Scholar
Probing the Architecture of the Budding Yeast Inner Kinetochore
C. Drysdale
20180 citations
Semantic Scholar

Jackson Gamer

×14

Morgan Yapundich×14

J. Haro-Mora×13

Aylin C. Bonifacino×8

Allen E. Krouse×8

N. Linde×8

R. Donahue×8

Alexis Leonard×7