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A. Shahine · SciRah

Researcher profile · Semantic Scholar

A. Shahine

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A. Shahine — researcher profile on SciRah

h-index: 11
Works: 41
Citations: 359

Most-cited papers

Human γδ T cells recognize CD1b by two distinct mechanisms
J. F. Reijneveld, T. Ocampo, A. Shahine, B. S. Gully +5 more
2020Proceedings of the National Academy of Sciences of the United States of America55 citations Open access
Semantic Scholar
Tetrahydrolipstatin Inhibition, Functional Analyses, and Three-dimensional Structure of a Lipase Essential for Mycobacterial Viability*
P. Crellin, J. Vivian, J. Scoble, Frances M. E. Chow +10 more
2010Journal of Biological Chemistry39 citations Open access
Semantic Scholar
CD1 lipidomes reveal lipid binding motifs and size-based antigen display mechanisms
Shouxiong Huang, A. Shahine, T. Cheng, Yi-Ling Chen +12 more
2023Cell38 citations Open access
Semantic Scholar
A single-domain bispecific antibody targeting CD1d and the NKT T-cell receptor induces a potent antitumor response
R. Lameris, A. Shahine, D. Pellicci, Adam P. Uldrich +13 more
2020Nature Cancer34 citations
Semantic Scholar
A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids
A. Shahine, P. Reinink, J. F. Reijneveld, S. Gras +10 more
2019Nature Communications30 citations Open access
Semantic Scholar
Staphylococcal phosphatidylglycerol antigens activate human T cells via CD1a
G. Monnot, M. Wegrecki, T. Cheng, Yi-Ling Chen +21 more
2022Nature Immunology28 citations Open access
Semantic Scholar
Lipids hide or step aside for CD1-autoreactive T cell receptors
R. Cotton, A. Shahine, Jamie Rossjohn, D. Moody
2018Current Opinion in Immunology25 citations Open access
Semantic Scholar
The intricacies of self‐lipid antigen presentation by CD1b
A. Shahine
2018Molecular Immunology17 citations Open access
Semantic Scholar
A structural perspective of how T cell receptors recognize the CD1 family of lipid antigen–presenting molecules
Thinh-Phat Cao, A. Shahine, Liam R. Cox, G. Besra +2 more
2024Journal of Biological Chemistry12 citations Open access
Semantic Scholar
Rational design of a hydrolysis-resistant mycobacterial phosphoglycolipid antigen presented by CD1c to T cells
J. F. Reijneveld, Laura Mariño, T. Cao, T. Cheng +11 more
2021Journal of Biological Chemistry12 citations Open access
Semantic Scholar
Molecular recognition of microbial lipid-based antigens by T-cells
S. Gras, I. van Rhijn, A. Shahine, J. Le Nours
2018Cellular and Molecular Life Sciences11 citations Open access
Semantic Scholar
Molecular features of lipid-based antigen presentation by group 1 CD1 molecules.
J. Le Nours, A. Shahine, S. Gras
2017Seminars in Cell and Developmental Biology11 citations
Semantic Scholar
Cloning, expression, purification and crystallographic studies of galectin-11 from domestic sheep (Ovis aries).
D. Sakthivel, D. Littler, A. Shahine, S. Troy +4 more
2015Acta Crystallographica Section F Structural Biology Communications11 citations Open access
Semantic Scholar
The oligomeric assembly of galectin-11 is critical for anti-parasitic activity in sheep (Ovis aries)
D. Sakthivel, S. Preston, R. Gasser, T. P. Soares da Costa +10 more
2020Communications Biology9 citations Open access
Semantic Scholar
CD1 Displays Its Own Negative Regulators
A. Shahine, I. van Rhijn, J. Rossjohn, B. Moody
2023Current Opinion in Immunology7 citations Open access
Semantic Scholar
Novel Molecular Insights into Human Lipid-Mediated T Cell Immunity
A. Shahine, M. Wegrecki, J. Le Nours
2021International Journal of Molecular Sciences5 citations Open access
Semantic Scholar
Enhanced CD1d phosphatidylserine presentation using a single-domain antibody promotes immunomodulatory CD1d-TIM-3 interactions
R. Lameris, A. Shahine, Myrthe Veth, Bart A. Westerman +6 more
2023Journal for ImmunoTherapy of Cancer4 citations Open access
Semantic Scholar
A structural characterization of the isoniazid Mycobacterium tuberculosis drug target, Rv2971, in its unliganded form.
A. Shahine, A. Prasetyoputri, J. Rossjohn, T. Beddoe
2014Acta Crystallographica Section F Structural Biology Communications3 citations Open access
Semantic Scholar
αβ T-cell receptor recognition of self-phosphatidylinositol presented by CD1b
R. Farquhar, I. van Rhijn, D. Moody, J. Rossjohn +1 more
2022Journal of Biological Chemistry2 citations Open access
Semantic Scholar
A structural and functional investigation of a novel protein from Mycobacterium smegmatis implicated in mycobacterial macrophage survivability.
A. Shahine, D. Littler, Rajini Brammananath, P. Chan +4 more
2014Acta Crystallographica Section D: Biological Crystallography2 citations
Semantic Scholar
cell receptor recognition of CD1b presenting a mycobacterial glycolipid
Stephanie Gras, I. van Rhijn, A. Shahine, T. Cheng +8 more
2 citations
Semantic Scholar
Human gamma delta T cells recognize CD1b by two distinct mechanisms
J. F. Reijneveld, T. Ocampo, A. Shahine, B. S. Gully +5 more
20201 citations
Semantic Scholar
Cloning, expression, purification and preliminary X-ray diffraction studies of a mycobacterial protein implicated in bacterial survival in macrophages.
A. Shahine, P. Chan, D. Littler, J. Vivian +5 more
2013Acta Crystallographica. Section F : Structural Biology and Crystallization Communications1 citations Open access
Semantic Scholar
CD1a-Mediated Presentation of Canonical Microbial Peptides to T Cells
B. J. de Andrade Silva, A. de Jong, Linda A. Fischbacher, Maria Angela M. Marques +23 more
2026bioRxiv0 citations
Semantic Scholar
Conserved T cell receptor usage underpins recognition of CD1c presenting a mycobacterial lipid
Thinh-Phat Cao, Caroline Soliman, S. Redmond, Tori Tappen +12 more
2026bioRxiv0 citations
Semantic Scholar
Sideways lipid presentation by the antigen-presenting molecule CD1c
Thinh-Phat Cao, Guan-Ru Liao, T. Cheng, Yan-Qiong Chen +14 more
2025bioRxiv0 citations Open access
Semantic Scholar
CD1c with antigen analogue 1
T.-P. Cao, A. Shahine, J. Rossjohn
20210 citations
Semantic Scholar
CD1c with antigen analogue 2
T.-P. Cao, A. Shahine, J. Rossjohn
20210 citations
Semantic Scholar
CD1c with antigen analogue 3
T.-P. Cao, A. Shahine, J. Rossjohn
20210 citations
Semantic Scholar
Human CD1d presenting alpha-Galactosylceramide in complex with VHH nanobody 1D5
A. Shahine, J. Rossjohn
20200 citations
Semantic Scholar
Crystal structure of human CD1d presenting alpha-Galactosylceramide in complex with NKT12 TCR and VHH nanobody 1D12
A. Shahine, J. Rossjohn
20200 citations
Semantic Scholar
Human CD1d presenting alpha-Galactosylceramide in complex with VHH nanobody 1D22
A. Shahine, J. Rossjohn
20200 citations
Semantic Scholar
Crystal structure of the unliganded PG10 TCR
A. Shahine, J. Rossjohn
20190 citations
Semantic Scholar
Crystal structure of BC8B TCR-CD1b-PC complex
A. Shahine, J. Rossjohn
20190 citations
Semantic Scholar
Crystal structure of the unliganded Clone 2 TCR
A. Shahine, J. Rossjohn
20190 citations
Semantic Scholar
Crystal structure of PG90 TCR-CD1b-PG complex
A. Shahine, S. Gras, J. Rossjohn
20170 citations
Semantic Scholar
Crystal structure of the unliganded PG90 TCR
A. Shahine, S. Gras, J. Rossjohn
20170 citations
Semantic Scholar
Crystal Structure of Human CD1b in Complex with POPC
A. Shahine, S. Gras, J. Rossjohn
20170 citations
Semantic Scholar
Crystal structure of GEM42 TCR-CD1b-GMM complex
S. Gras, A. Shahine, J. Le Nours, J. Rossjohn
20160 citations
Semantic Scholar
Crystal Structure of human CD1b in complex with C36-GMM
S. Gras, A. Shahine, J. Le Nours, J. Rossjohn
20160 citations
Semantic Scholar
Structural characterization of three novel proteins from Mycobacterium species vital for their survival
A. Shahine
20160 citations
Semantic Scholar

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