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Duo-Zhi Chen · SciRah

Researcher profile · Semantic Scholar

Duo-Zhi Chen

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Duo-Zhi Chen — researcher profile on SciRah

h-index: 16
Works: 49
Citations: 725

Most-cited papers

Small-molecule modulation of Wnt signaling via modulating the Axin-LRP5/6 interaction.
Sheng Wang, Ju-Zhong Yin, Duo-Zhi Chen, Fen Nie +12 more
2013Nature Chemical Biology87 citations
Semantic Scholar
Aphanamixoid A, a potent defensive limonoid, with a new carbon skeleton from Aphanamixis polystachya.
Jie-Yun Cai, Yu Zhang, Shihong Luo, Duo-Zhi Chen +6 more
2012Organic Letters61 citations
Semantic Scholar
Design, Synthesis and Structure-Activity Relationship Optimization of Lycorine Derivatives for HCV Inhibition
Duo-Zhi Chen, Jie-Yun Cai, Jun-Jun Cheng, Chen-Xu Jing +4 more
2015Scientific Reports43 citations Open access
Semantic Scholar
Bioactive Limonoid Constituents of Munronia henryi.
Ying Yan, Jian-Xin Zhang, Tao Huang, Xinxiao Mao +7 more
2015Journal of Natural Products34 citations
Semantic Scholar
Limonoids from Aphanamixis polystachya and their antifeedant activity.
Jie-Yun Cai, Duo-Zhi Chen, Shihong Luo, Ning-Chuan Kong +9 more
2014Journal of Natural Products32 citations
Semantic Scholar
Cyclohexane-fused octahydroquinolizine alkaloids from Myrioneuron faberi with activity against hepatitis C virus.
Ming-Ming Cao, Yu Zhang, Xiao-Hui Li, Zong-Gen Peng +9 more
2014Journal of Organic Chemistry32 citations
Semantic Scholar
Novel nucleocapsid protein-targeting phenanthridine inhibitors of SARS-CoV-2
Yi-Ting Wang, Xin-Yan Long, Xiao Ding, Shi-Rui Fan +11 more
2021European Journal of Medicinal Chemistry29 citations Open access
Semantic Scholar
Lycorine-derived phenanthridine downregulators of host Hsc70 as potential hepatitis C virus inhibitors.
Duo-Zhi Chen, Jie-Yun Cai, Ju-Zhong Yin, Jian-Dong Jiang +9 more
2015Future Medicinal Chemistry28 citations
Semantic Scholar
A new Amaryllidaceae alkaloid from the bulbs of Lycoris radiata
Sheng-Dian Huang, Yu Zhang, Hong He, Shi-Fei Li +5 more
2013Chinese Journal of Natural Medicines26 citations Open access
Semantic Scholar
Design, Synthesis, and Structural Optimization of Lycorine-Derived Phenanthridine Derivatives as Wnt/β-Catenin Signaling Pathway Agonists.
Duo-Zhi Chen, Chen-Xu Jing, Jie-Yun Cai, Jibo Wu +5 more
2016Journal of Natural Products24 citations
Semantic Scholar
New vobasinyl-ibogan type bisindole alkaloids from Tabernaemontana corymbosa.
Yu Zhang, Ling-Li Guo, Guangmei Yang, Feng Guo +4 more
2015Fitoterapia24 citations
Semantic Scholar
Two novel diterpenoid heterodimers, Bisebracteolasins A and B, from Euphorbia ebracteolata Hayata, and the cancer chemotherapeutic potential of Bisebracteolasin A
Wen-juan Yuan, Xiao Ding, Zhe Wang, Bi-Juan Yang +8 more
2017Scientific Reports22 citations Open access
Semantic Scholar
Evaluation of anti-HCV activity and SAR study of (+)-lycoricidine through targeting of host heat-stress cognate 70 (Hsc70).
Duo-Zhi Chen, Jian-Dong Jiang, Keke Zhang, Hong-Ping He +8 more
2013Bioorganic & Medicinal Chemistry Letters22 citations
Semantic Scholar
Three new diterpenes with cytotoxic activity from the roots of Euphorbia ebracteolata Hayata
Wen-juan Yuan, Guohong Yang, Jiahui Zhang, Yu Zhang +4 more
201621 citations Open access
Semantic Scholar
Cytotoxic indole alkaloids from Melodinus khasianus and Melodinus tenuicaudatus.
Wen-fang Yi, Duo-Zhi Chen, Xiao Ding, Xiao-Nian Li +4 more
2018Fitoterapia20 citations
Semantic Scholar
Daphmacromines A-J, alkaloids from Daphniphyllum macropodum.
Ming-Ming Cao, Yu Zhang, Hong-Ping He, Shi-Fei Li +6 more
2012Journal of Natural Products18 citations
Semantic Scholar
Anti-TMV Effects of Amaryllidaceae Alkaloids Isolated from the Bulbs of Lycoris radiata and Lycoricidine Derivatives
Dongqiong Yang, Zhaonan Chen, Duo-Zhi Chen, Xiao-Jiang Hao +1 more
2018Natural Products and Bioprospecting16 citations Open access
Semantic Scholar
Spiramine derivatives induce apoptosis of Bax(-/-)/Bak(-/-) cell and cancer cells.
Yan Chen, Li Huang, Hong-chun Liu, Duo-Zhi Chen +6 more
2014Bioorganic & Medicinal Chemistry Letters16 citations
Semantic Scholar
Stelleraguaianone B and C, two new sesquiterpenoids from Stellera chamaejasme L.
Chen-Xu Jing, Jing-jing Guo, Bi-Juan Yang, Shi-Rui Fan +3 more
2019Fitoterapia15 citations
Semantic Scholar
Alkaloids with Different Carbon Units from Myrioneuron faberi.
Ming-Ming Cao, Yu Zhang, Sheng-Dian Huang, Ying-Tong Di +7 more
2015Journal of Natural Products15 citations
Semantic Scholar
Phenanthridine Derivative Host Heat Shock Cognate 70 Down-Regulators as Porcine Epidemic Diarrhea Virus Inhibitors.
Duo-Zhi Chen, Shi-Rui Fan, Bi-Juan Yang, Huo-Chun Yao +8 more
2021Journal of Natural Products14 citations
Semantic Scholar
Aphananoid A is an anti-inflammatory limonoid with a new 5/6/5 fused ring featuring a C24 carbon skeleton from Aphanamixis polystachya.
Bi-Juan Yang, Shi-Rui Fan, Jie-Yun Cai, Yi-Ting Wang +4 more
2020Journal of Organic Chemistry14 citations Open access
Semantic Scholar
Diterpenes with potential treatment of vitiligo from the aerials parts of Euphorbia antiquorum L.
Wen-juan Yuan, Wen-Fen Gao, Jiang-Yu Zhao, Yu Zhang +4 more
2020Fitoterapia13 citations
Semantic Scholar
Efficient synthesis of new phenanthridine Wnt/β-catenin signaling pathway agonists.
Duo-Zhi Chen, Heng Zhang, Chen-Xu Jing, Xiao-Li He +6 more
2018European journal of medicinal chemistry11 citations
Semantic Scholar
Four new tetracyclic alkaloids with cis-decahydroquinoline motif from Myrioneuron effusum.
Jiahui Zhang, Jing-jing Guo, Yu-Xi Yuan, Yan-Hui Fu +6 more
2016Fitoterapia10 citations Open access
Semantic Scholar
Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new anti-vitiligo compounds.
Bi-Juan Yang, Shi-Rui Fan, Xin-Fang Zhang, Jie-Yun Cai +5 more
2021Bioorganic chemistry (Print)9 citations
Semantic Scholar
Structural Revision of Macropodumine A and Structure of 2-Deoxymacropodumine A, Daphniphyllum Alkaloids with 11-Membered Macrolactone Rings.
Jiahui Zhang, Pei Cao, Yuan Ma, Xin Fang +6 more
2018Journal of Natural Products9 citations
Semantic Scholar
Two new cytotoxic cycloartane triterpenoids from Aphanamixis polystachya (Wall.) R. N. Parker
Yi-Ting Wang, Shi-Rui Fan, Jie-Yun Cai, Jing-jing Guo +4 more
2021Natural Product Research7 citations
Semantic Scholar
Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/β-catenin signalling pathway agonists.
Duo-Zhi Chen, Bi-Juan Yang, Xiao-Li He, Shi-Rui Fan +6 more
2019Bioorganic chemistry (Print)7 citations
Semantic Scholar
(±)-Perforison A, A Pair of New Chromone Enantiomers from Harrisonia perforata
Wen-juan Yuan, Wen-Fen Gao, Jiahui Zhang, Pei Cao +5 more
2017Natural Product Communications7 citations Open access
Semantic Scholar
Daphmacrimines A-K, Daphniphyllum alkaloids from Daphniphyllum macropodum Miq.
Lili Xu, Zhen-Peng Niu, Duo-Zhi Chen, Yu Zhang +7 more
2024Phytochemistry6 citations Open access
Semantic Scholar
Utilizing artificial intelligence for precision exploration of N protein targeting phenanthridine sars-cov-2 inhibitors: A novel approach.
Zheng-rui Xiang, Shi-Rui Fan, Juan Ren, Ting Ruan +8 more
2024European journal of medicinal chemistry6 citations Open access
Semantic Scholar
Two new bioactive lignans from leaves and twigs of Cleistanthus concinnus Croizat
Shi-Rui Fan, Jing-jing Guo, Yi-Ting Wang, Bi-Juan Yang +2 more
2019Natural Product Research5 citations
Semantic Scholar
Chemical Constituents from the Stems of Manihot esculenta
Ya-Mei Pan, Yu Zhang, Xiao-na Wang, He-Ping Chen +6 more
2015Natural Products and Bioprospecting5 citations Open access
Semantic Scholar
Five new limonoids isolated from Walsura robusta
L. Hou, Cui-Xuan Mei, C. Yuan, Gui-Hua Tang +5 more
2023Natural Products and Bioprospecting3 citations Open access
Semantic Scholar
Rapid Synthesis of Ismine, a Bioactive Amaryllidaceae Alkaloid
Jing-jing Guo, Bi-Juan Yang, Chen-Xu Jing, Duo-Zhi Chen +1 more
20173 citations
Semantic Scholar
Diterpenoids target SARS-CoV-2 RdRp from the roots of Euphorbia fischeriana Steud
Ting Ruan, Zheng-rui Xiang, Yun-Wu Zhang, Shi-Rui Fan +9 more
2024Frontiers in Plant Science2 citations Open access
Semantic Scholar
Potential SARS-CoV-2 Mpro steroid inhibitors from Aphanamixis polystachya (Wall.) R. N. Parker.
Juan Ren, Shi-Rui Fan, Jieyun Cai, Ting Ruan +9 more
2024Fitoterapia2 citations
Semantic Scholar
An Explorer of Chemical Biology of Plant Natural Products in Southwest China, Xiaojiang Hao
Yue-Mao Shen, Duo-Zhi Chen
2018Natural Products and Bioprospecting2 citations Open access
Semantic Scholar
Synthesis of 4-Ethyl-5-Methyl-5,6-Dihydrophenanthridine-8,9-Diol as the Key Intermediate of Potent Agonists of the Wnt Signalling Pathway
Chen-Xu Jing, Jie-Yun Cai, Yu Zhang, Duo-Zhi Chen +1 more
20152 citations
Semantic Scholar
New Phragmalin-Type Limonoid Orthoesters from the Bark of Chukrasia tabularis var. velutina
Wen-Xing Liu, Duo-Zhi Chen, Jia-Yin Ding, Xiao-Jiang Hao +1 more
20152 citations
Semantic Scholar
Aphanamixis polystachya(センダン科)からのリモノイド類とそれらの摂食阻害活性
Jie-Yun Cai, Duo-Zhi Chen, Shihong Luo, Ning-Chuan Kong +9 more
20141 citations
Semantic Scholar
Isolation of dihydroagarofuran sesquiterpene from the fruits of Tripterygium hypoglaucum and evaluation of their anti-inflammatory activity.
Shi-Li Wu, Xing Yang, Wen Ning, Gang Wu +7 more
2025Phytochemistry0 citations
Semantic Scholar
A small-molecule lycorine derivative protects from obesity by targeting Na+/K+-ATPase α3 independent of food intake suppression
Henan Zhang, Yunfu Zhou, Duo-Zhi Chen, Yi-Bao Zhang +10 more
2025bioRxiv0 citations Open access
Semantic Scholar
基于虚拟筛选探讨菲啶类衍生物抗新型冠状病毒(SARS-CoV-2)潜力
Yi-Ting Wang, Shi-Rui Fan, Bi-Juan Yang, Duo-Zhi Chen +1 more
20200 citations
Semantic Scholar
Axin, the classic scaffold protein of Wnt/β-catenin signalling as a potential drug-target for vitiligo
Duo-Zhi Chen, Shi-Rui Fan, Xue-Ying Lu, Chen-Xu Jing +8 more
20200 citations Open access
Semantic Scholar
一种HCV抑制剂中间体9-羟基-6-氧-4-甲基菲啶的全合成
Bi-Juan Yang, Guang-Jing Liu, Jing-jing Guo, Chen-Xu Jing +2 more
20160 citations
Semantic Scholar
Aphanamixis polystachya(センダン科)からのリモノイド類とそれらの摂食阻害活性 | 文献情報 | J-GLOBAL 科学技術総合リンクセンター
Jie-Yun Cai, Duo-Zhi Chen, Shihong Luo, Ning-Chuan Kong +9 more
20140 citations
Semantic Scholar
Phenanthridine derivative as well as medicinal composition, preparation method and application thereof
Xiao-Jiang Hao, Duo-Zhi Chen, Jun-lin Yin, Zong-Gen Peng +5 more
20130 citations
Semantic Scholar

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Xiao-Jiang Hao×33
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Yu Zhang×26
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Yu Zhang — researcher profile on SciRah
Ying-Tong Di×21
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Shun-Lin Li×20
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Chen-Xu Jing×14

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Bi-Juan Yang×14

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Shi-Rui Fan×13

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Hong-Ping He×12

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Yi-Ting Wang×9

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Xiao-Jiang Hao×7

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Jing-jing Guo×7

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