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T. Tsutsumi · SciRah

Researcher profile · Semantic Scholar

T. Tsutsumi

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T. Tsutsumi — researcher profile on SciRah

h-index: 40
Works: 141
Citations: 6,514

Most-cited papers

Characterization and antiviral susceptibility of SARS-CoV-2 Omicron BA.2
Ryuta Uraki, M. Kiso, S. Iida, M. Imai +64 more
2022Nature197 citations Open access
Semantic Scholar
Humoral immune evasion of the omicron subvariants BQ.1.1 and XBB
Ryuta Uraki, M. Ito, Yuri Furusawa, S. Yamayoshi +13 more
2022Lancet. Infectious Diseases (Print)167 citations Open access
Semantic Scholar
Characterization and antiviral susceptibility of SARS-CoV-2 Omicron/BA.2
Y. Kawaoka, Ryuta Uraki, M. Kiso, S. Iida +46 more
2022Research Square93 citations Open access
Semantic Scholar
Helicobacter pylori infection is not associated with fatty liver disease including non-alcoholic fatty liver disease: a large-scale cross-sectional study in Japan
Kazuya Okushin, Yu Takahashi, N. Yamamichi, Takeshi Shimamoto +12 more
2015BMC Gastroenterology89 citations Open access
Semantic Scholar
Antiviral and bivalent vaccine efficacy against an omicron XBB.1.5 isolate
Ryuta Uraki, M. Ito, M. Kiso, S. Yamayoshi +15 more
2023Lancet. Infectious Diseases (Print)81 citations Open access
Semantic Scholar
HBx-induced degradation of Smc5/6 complex impairs homologous recombination-mediated repair of damaged DNA.
Kazuma Sekiba, Motoyuki Otsuka, Kazuyoshi Funato, Yu Miyakawa +8 more
2021Journal of Hepatology81 citations Open access
Semantic Scholar
Unique Gut Microbiome in HIV Patients on Antiretroviral Therapy (ART) Suggests Association with Chronic Inflammation
A. Ishizaka, M. Koga, Taketoshi Mizutani, P. Parbie +15 more
2021Microbiology spectrum78 citations Open access
Semantic Scholar
Correlation Analysis between Gut Microbiota Alterations and the Cytokine Response in Patients with Coronavirus Disease during Hospitalization
Taketoshi Mizutani, A. Ishizaka, M. Koga, Kazuhiko Ikeuchi +11 more
2022Microbiology spectrum77 citations Open access
Semantic Scholar
Hepatic Sdf2l1 controls feeding-induced ER stress and regulates metabolism
Takayoshi Sasako, M. Ohsugi, N. Kubota, S. Itoh +21 more
2019Nature Communications75 citations Open access
Semantic Scholar
Helicobacter pylori infection and liver diseases: Epidemiology and insights into pathogenesis
Kazuya Okushin, T. Tsutsumi, Kazuhiko Ikeuchi, A. Kado +5 more
2018World Journal of Gastroenterology61 citations Open access
Semantic Scholar
Hepatocarcinogenesis in Hepatitis C: HCV Shrewdly Exacerbates Oxidative Stress by Modulating both Production and Scavenging of Reactive Oxygen Species
H. Fujinaga, T. Tsutsumi, H. Yotsuyanagi, K. Moriya +1 more
2011Oncology58 citations
Semantic Scholar
The intrahepatic expression levels of bile acid transporters are inversely correlated with the histological progression of nonalcoholic fatty liver disease
Kazuya Okushin, T. Tsutsumi, K. Enooku, H. Fujinaga +6 more
2016Journal of gastroenterology56 citations
Semantic Scholar
Hepatic FATP5 expression is associated with histological progression and loss of hepatic fat in NAFLD patients
K. Enooku, T. Tsutsumi, Mayuko Kondo, N. Fujiwara +20 more
2019Journal of gastroenterology55 citations
Semantic Scholar
Pathogenesis of lipid metabolism disorder in hepatitis C: polyunsaturated fatty acids counteract lipid alterations induced by the core protein.
H. Miyoshi, K. Moriya, T. Tsutsumi, S. Shinzawa +10 more
2011Journal of Hepatology55 citations
Semantic Scholar
Role of Microbiota in Viral Infections and Pathological Progression
Taketoshi Mizutani, A. Ishizaka, M. Koga, T. Tsutsumi +1 more
2022Viruses44 citations Open access
Semantic Scholar
Hepatitis C virus core protein compromises iron‐induced activation of antioxidants in mice and HepG2 cells
K. Moriya, H. Miyoshi, S. Shinzawa, T. Tsutsumi +5 more
2010Journal of Medical Virology37 citations
Semantic Scholar
Hepatic IRS1 and ß-catenin expression is associated with histological progression and overt diabetes emergence in NAFLD patients
K. Enooku, Mayuko Kondo, N. Fujiwara, Takayoshi Sasako +20 more
2018Journal of gastroenterology32 citations Open access
Semantic Scholar
Characterization of the SARS-CoV-2 B.1.621 (Mu) variant
Peter J. Halfmann, M. Kuroda, T. Armbrust, J. Theiler +26 more
2022Science Translational Medicine31 citations Open access
Semantic Scholar
Mitochondrial iron accumulation exacerbates hepatic toxicity caused by hepatitis C virus core protein.
Shuichi Sekine, Konomi Ito, Haruna Watanabe, T. Nakano +9 more
2015Toxicology and Applied Pharmacology31 citations
Semantic Scholar
Association of coagulopathy with liver dysfunction in patients with COVID‐19
T. Tsutsumi, M. Saito, H. Nagai, Shinya Yamamoto +8 more
2020Hepatology Research29 citations Open access
Semantic Scholar
In Vitro Efficacy of Antiviral Agents against Omicron Subvariant BA.4.6
E. Takashita, S. Yamayoshi, Peter J. Halfmann, N. Wilson +22 more
2022New England Journal of Medicine24 citations Open access
Semantic Scholar
Dysregulation of miRNA in chronic hepatitis B is associated with hepatocellular carcinoma risk after nucleos(t)ide analogue treatment.
H. Wakasugi, Hideaki Takahashi, T. Niinuma, Hiroshi Kitajima +27 more
2018Cancer Letters24 citations
Semantic Scholar
Noninvasive diagnostic criteria for nonalcoholic steatohepatitis based on gene expression levels in peripheral blood mononuclear cells
A. Kado, T. Tsutsumi, K. Enooku, H. Fujinaga +5 more
2019Journal of gastroenterology20 citations
Semantic Scholar
Changes in survival and causes of death among people living with HIV: Three decades of surveys from Tokyo, one of the Asian metropolitan cities.
Haruka Tsuda, M. Koga, M. Nojima, Tomoe Senkoji +7 more
2021Journal of Infection and Chemotherapy19 citations Open access
Semantic Scholar
Multicenter, single-blind, randomized controlled study of the efficacy and safety of favipiravir and nafamostat mesilate in patients with COVID-19 pneumonia
Mahoko Ikeda, S. Okugawa, Kosuke Kashiwabara, T. Moritoyo +33 more
2023International Journal of Infectious Diseases18 citations Open access
Semantic Scholar
CD4/CD8 ratio predicts the cellular immune response to acute hepatitis C in HIV-coinfected adults.
Hidenori Sato, E. Adachi, L. A. Lim, M. Koga +3 more
2019Journal of Infection and Chemotherapy17 citations
Semantic Scholar
Deconvoluting the Composition of Low-Frequency Hepatitis C Viral Quasispecies: Comparison of Genotypes and NS3 Resistance-Associated Variants between HCV/HIV Coinfected Hemophiliacs and HCV Monoinfected Patients in Japan
Masato Ogishi, H. Yotsuyanagi, T. Tsutsumi, H. Gatanaga +6 more
2015PLoS ONE17 citations Open access
Semantic Scholar
Teicoplanin and vancomycin as treatment for glycopeptide-susceptible Enterococcus faecium bacteraemia: a propensity score-adjusted non-inferior comparative study
Ryo Yamaguchi, Takehito Yamamoto, Koh Okamoto, Sohei Harada +3 more
2023Journal of Antimicrobial Chemotherapy16 citations Open access
Semantic Scholar
Prolonged Gut Dysbiosis and Fecal Excretion of Hepatitis A Virus in Patients Infected with Human Immunodeficiency Virus
A. Ishizaka, M. Koga, Taketoshi Mizutani, L. A. Lim +14 more
2021Viruses16 citations Open access
Semantic Scholar
Efficacy of antivirals and bivalent mRNA vaccines against SARS-CoV-2 isolate CH.1.1
Ryuta Uraki, M. Ito, M. Kiso, S. Yamayoshi +15 more
2023Lancet. Infectious Diseases (Print)15 citations Open access
Semantic Scholar
Antiviral effect and safety of nafamostat mesilate in patients with mild early-onset COVID-19: An exploratory multicenter randomized controlled clinical trial.
S. Okugawa, Mahoko Ikeda, K. Kashiwabara, T. Moritoyo +18 more
2023International Journal of Antimicrobial Agents15 citations Open access
Semantic Scholar
An outbreak of USA300 MRSA among people with HIV in Japan.
Kazuhiko Ikeuchi, E. Adachi, T. Sasaki, Masato Suzuki +7 more
2020Journal of Infectious Diseases13 citations
Semantic Scholar
Heterozygous knockout of Bile salt export pump ameliorates liver steatosis in mice fed a high-fat diet
Kazuya Okushin, T. Tsutsumi, Kazuhiko Ikeuchi, A. Kado +7 more
2020PLoS ONE12 citations Open access
Semantic Scholar
Casirivimab/imdevimab for active COVID-19 pneumonia persisted for nine months in a patient with follicular lymphoma during anti-CD20 therapy.
H. Nagai, M. Saito, E. Adachi, Yuko Sakai-Tagawa +7 more
2022Japanese journal of infectious diseases (Print)11 citations Open access
Semantic Scholar
Antiviral efficacy against and replicative fitness of an XBB.1.9.1 clinical isolate
Ryuta Uraki, M. Ito, M. Kiso, S. Yamayoshi +16 more
2023iScience10 citations Open access
Semantic Scholar
Triglyceride level and soft drink consumption predict nonalcoholic fatty liver disease in nonobese male adolescents
A. Kado, Yukiko Inoue, K. Moriya, T. Tsutsumi +5 more
2023Hepatology Research10 citations Open access
Semantic Scholar
Prevalence of hepatitis A immunity and decision-tree analysis among HIV-infected men who have sex with men, in Tokyo.
T. Koibuchi, M. Koga, T. Kikuchi, Taizo Horikomi +5 more
2019Clinical Infectious Diseases10 citations Open access
Semantic Scholar
Antibody induction and immune response in nasal cavity by third dose of SARS-CoV-2 mRNA vaccination
A. Ishizaka, M. Koga, Taketoshi Mizutani, Ryuta Uraki +8 more
2023Virology Journal9 citations Open access
Semantic Scholar
Anti-spike protein antibody titer at the time of breakthrough infection of SARS-CoV-2 omicron
E. Adachi, Etsuko Nagai, M. Saito, Masamichi Isobe +5 more
2022Journal of Infection and Chemotherapy9 citations Open access
Semantic Scholar
Noninvasive approach to indicate risk factors of nonalcoholic steatohepatitis overlapping autoimmune hepatitis based on peripheral lymphocyte pattern
A. Kado, T. Tsutsumi, H. Yotsuyanagi, Kazuhiko Ikeuchi +4 more
2023Journal of gastroenterology8 citations Open access
Semantic Scholar
Predictors associated with a better response to the Japanese aluminum‐free hepatitis A vaccine, Aimmugen®, for people living with HIV
M. Koga, Tomoe Senkoji, M. Kubota, A. Ishizaka +13 more
2021Hepatology Research8 citations Open access
Semantic Scholar
An Outbreak of USA300 Methicillin-Resistant Staphylococcus aureus Among People With HIV in Japan
Kazuhiko Ikeuchi, E. Adachi, T. Sasaki, Masato Suzuki +7 more
2020Journal of Infectious Diseases8 citations
Semantic Scholar
Decreased antioxidant-related superoxide dismutase 1 expression in peripheral immune cells indicates early ethanol exposure
A. Kado, Kyoji Moriya, Yukiko Inoue, S. Yanagimoto +3 more
2024Scientific Reports7 citations Open access
Semantic Scholar
Differential peripheral memory T cell subsets sensitively indicate the severity of nonalcoholic fatty liver disease
A. Kado, T. Tsutsumi, H. Yotsuyanagi, Kazuhiko Ikeuchi +4 more
2023Hepatology Research7 citations Open access
Semantic Scholar
Comparison of clinical features of hepatitis A in people living with HIV between pandemic in 1999-2000 and that in 2017-2018 in a metropolitan area of Japan.
M. Koga, L. A. Lim, Masato Ogishi, H. Satoh +9 more
2020Japanese journal of infectious diseases (Print)7 citations Open access
Semantic Scholar
Transient depletion of T cells during COVID‐19 and seasonal influenza in people living with HIV
E. Adachi, M. Saito, H. Nagai, Kazuhiko Ikeuchi +3 more
2022Journal of Medical Virology6 citations Open access
Semantic Scholar
Fecal DNA Testing of TWIST1 Methylation Identifies Patients With Advanced Colorectal Adenoma Missed by Fecal Immunochemical Test for Hemoglobin
Y. Suehiro, Shinichi Hashimoto, Atsushi Goto, Y. Yamaoka +18 more
2020Clinical and Translational Gastroenterology6 citations Open access
Semantic Scholar
Modulation of duodenal and jejunal microbiota by rifaximin in mice with CCl4-induced liver fibrosis
Kazuhiko Ikeuchi, T. Tsutsumi, A. Ishizaka, Taketoshi Mizutani +4 more
2023Gut Pathogens5 citations Open access
Semantic Scholar
Favorable Outcome Following Sotrovimab Monoclonal Antibody in a Patient with Prolonged SARS-CoV-2 Omicron Infection with HIV/AIDS
E. Adachi, M. Saito, M. Koga, T. Tsutsumi +1 more
2022Internal medicine5 citations Open access
Semantic Scholar
Characterization of genetic mutations in hepatitis B virus isolated from HBsAg+/HBcAb+/HBsAb-/HBV DNA + Japanese blood donors
Ayako Sedohara, Kazuaki Takahashi, T. Tsutsumi, Keiko Arai +4 more
2025Scientific Reports4 citations Open access
Semantic Scholar

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H. Yotsuyanagi×41
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H. Yotsuyanagi — researcher profile on SciRah
M. Koga×27
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M. Koga — researcher profile on SciRah
E. Adachi×24
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E. Adachi — researcher profile on SciRah
Kazuhiko Ikeuchi×18
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Kazuhiko Ikeuchi — researcher profile on SciRah

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M. Saito — researcher profile on SciRah

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K. Moriya — researcher profile on SciRah

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K. Koike — researcher profile on SciRah

Kazuya Okushin×13

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Kazuya Okushin — researcher profile on SciRah

S. Yamayoshi×10

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S. Yamayoshi — researcher profile on SciRah

Kiyoko Iwatsuki-Horimoto×10

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Kiyoko Iwatsuki-Horimoto — researcher profile on SciRah

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Y. Kawaoka — researcher profile on SciRah

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A. Kado — researcher profile on SciRah