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R. Lai · SciRah

Researcher profile · Semantic Scholar

R. Lai

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R. Lai — researcher profile on SciRah

h-index: 60
Works: 293
Citations: 13K

Most-cited papers

Mitochondrial delivery of doxorubicin via triphenylphosphine modification for overcoming drug resistance in MDA-MB-435/DOX cells.
Min Han, M. Vakili, Hoda Soleymani Abyaneh, Ommoleila Molavi +2 more
2014Molecular Pharmaceutics203 citations
Semantic Scholar
STAT3 in Cancer—Friend or Foe?
Hai-Feng Zhang, R. Lai
2014Cancers137 citations Open access
Semantic Scholar
The Changing Epidemiology of Posttransplant Lymphoproliferative Disorder in Adult Solid Organ Transplant Recipients Over 30 Years: A Single-center Experience
A. Peters, Michael Akinwumi, C. Cervera, C. Mabilangan +5 more
2018Transplantation77 citations
Semantic Scholar
Silibinin sensitizes chemo-resistant breast cancer cells to chemotherapy
Ommoleila Molavi, F. Narimani, Farshid Asiaee, Simin Sharifi +4 more
2016Pharmaceutical Biology69 citations Open access
Semantic Scholar
The PI3K/AKT/c‐MYC Axis Promotes the Acquisition of Cancer Stem‐Like Features in Esophageal Squamous Cell Carcinoma
Hai-Feng Zhang, Chengsheng Wu, A. Alshareef, N. Gupta +6 more
2016Stem Cells68 citations Open access
Semantic Scholar
Assessing SNP-SNP Interactions among DNA Repair, Modification and Metabolism Related Pathway Genes in Breast Cancer Susceptibility
Y. Sapkota, J. Mackey, R. Lai, C. Franco-Villalobos +6 more
2013PLoS ONE59 citations Open access
Semantic Scholar
The clinical and biological significance of STAT1 in esophageal squamous cell carcinoma
Ying Zhang, Ommoleila Molavi, M. Su, R. Lai
2014BMC Cancer58 citations Open access
Semantic Scholar
miR-200b suppresses invasiveness and modulates the cytoskeletal and adhesive machinery in esophageal squamous cell carcinoma cells via targeting Kindlin-2.
Hai-Feng Zhang, Kai Zhang, Lian-Di Liao, Li-Yan Li +14 more
2014Carcinogenesis58 citations Open access
Semantic Scholar
Autotaxin is an inflammatory mediator and therapeutic target in thyroid cancer.
M. Benesch, Yi M. Ko, Xiao-Yun Tang, Jay W. Dewald +6 more
2015Endocrine-Related Cancer54 citations Open access
Semantic Scholar
FGFR2 mutation in 46,XY sex reversal with craniosynostosis.
Stefan Bagheri-Fam, M. Ono, Li Li, Liang Zhao +9 more
2015Human Molecular Genetics49 citations Open access
Semantic Scholar
The Opposing Function of STAT3 as an Oncoprotein and Tumor Suppressor Is Dictated by the Expression Status of STAT3β in Esophageal Squamous Cell Carcinoma
Hai-Feng Zhang, Ye Chen, Chengsheng Wu, Zhi-Yong Wu +12 more
2015Clinical Cancer Research47 citations
Semantic Scholar
Loss of miR-200b promotes invasion via activating the Kindlin-2/integrin β1/AKT pathway in esophageal squamous cell carcinoma: An E-cadherin-independent mechanism
Hai-Feng Zhang, A. Alshareef, Chengsheng Wu, Shang Li +5 more
2015OncoTarget43 citations Open access
Semantic Scholar
The use of cellular thermal shift assay (CETSA) to study Crizotinib resistance in ALK-expressing human cancers
A. Alshareef, Hai-Feng Zhang, Yung-Hsing Huang, Chengsheng Wu +5 more
2016Scientific Reports42 citations Open access
Semantic Scholar
miR-200b induces cell cycle arrest and represses cell growth in esophageal squamous cell carcinoma.
Hai-Feng Zhang, A. Alshareef, Chengsheng Wu, Ji-Wei Jiao +4 more
2016Carcinogenesis37 citations Open access
Semantic Scholar
STAT3 but Not HIF-1α Is Important in Mediating Hypoxia-Induced Chemoresistance in MDA-MB-231, a Triple Negative Breast Cancer Cell Line
Hoda Soleymani Abyaneh, N. Gupta, A. Radziwon-Balicka, P. Jurasz +3 more
2017Cancers36 citations Open access
Semantic Scholar
Functional Plasticity of Gamma Delta T Cells and Breast Tumor Targets in Hypoxia
Gabrielle M. Siegers, Indrani Dutta, R. Lai, Lynne-Marie Postovit
2018Frontiers in Immunology35 citations Open access
Semantic Scholar
Epstein‐Barr virus associated smooth muscle tumors in solid organ transplant recipients: Incidence over 31 years at a single institution and review of the literature
Ryan J. Stubbins, Nassiba Alami Laroussi, A. Peters, S. Urschel +5 more
2018Transplant Infectious Disease35 citations
Semantic Scholar
Anti-CD30 antibody conjugated liposomal doxorubicin with significantly improved therapeutic efficacy against anaplastic large cell lymphoma
Ommoleila Molavi, Xiao-Bing Xiong, D. Douglas, N. Kneteman +5 more
2013Biomaterials35 citations Open access
Semantic Scholar
β-Catenin, a Sox2 binding partner, regulates the DNA binding and transcriptional activity of Sox2 in breast cancer cells.
Xiao-Xia Ye, Fang Wu, Chengsheng Wu, Peng Wang +5 more
2014Cellular Signalling34 citations
Semantic Scholar
Decoration of Anti-CD38 on Nanoparticles Carrying a STAT3 Inhibitor Can Improve the Therapeutic Efficacy Against Myeloma
Yung-Hsing Huang, M. Vakili, Ommoleila Molavi, Yuen Morrissey +6 more
2019Cancers33 citations Open access
Semantic Scholar
ERK is a negative feedback regulator for IFN-γ/STAT1 signaling by promoting STAT1 ubiquitination
Ying Zhang, Yelong Chen, Zhaoyong Liu, R. Lai
2018BMC Cancer32 citations Open access
Semantic Scholar
Sox2 suppresses the invasiveness of breast cancer cells via a mechanism that is dependent on Twist1 and the status of Sox2 transcription activity
Fang Wu, Xiao-Xia Ye, Peng Wang, K. Jung +6 more
2013BMC Cancer32 citations Open access
Semantic Scholar
Correlation of STAT1 with Apoptosis and Cell-Cycle Markers in Esophageal Squamous Cell Carcinoma
Ying Zhang, Yao-Zhong Zhang, Hailong Yun, R. Lai +1 more
2014PLoS ONE31 citations Open access
Semantic Scholar
A positive feedback loop involving the Wnt/β-catenin/MYC/Sox2 axis defines a highly tumorigenic cell subpopulation in ALK-positive anaplastic large cell lymphoma
Chengsheng Wu, Hai-Feng Zhang, N. Gupta, A. Alshareef +6 more
2016Journal of Hematology & Oncology30 citations Open access
Semantic Scholar
N-myristoyltransferase proteins in breast cancer: prognostic relevance and validation as a new drug target
J. Mackey, Justine Lai, Utkarsh Chauhan, Erwan Beauchamp +7 more
2021Breast Cancer Research and Treatment29 citations Open access
Semantic Scholar
Hypoxia Induces the Acquisition of Cancer Stem-like Phenotype Via Upregulation and Activation of Signal Transducer and Activator of Transcription-3 (STAT3) in MDA-MB-231, a Triple Negative Breast Cancer Cell Line
Hoda Soleymani Abyaneh, N. Gupta, A. Alshareef, K. Gopal +2 more
2018Cancer Microenvironment29 citations Open access
Semantic Scholar
STAT1 is phosphorylated and downregulated by the oncogenic tyrosine kinase NPM-ALK in ALK-positive anaplastic large-cell lymphoma.
Chengsheng Wu, Ommoleila Molavi, Hai-Feng Zhang, N. Gupta +8 more
2015Blood29 citations
Semantic Scholar
Methylation of miR-155-3p in mantle cell lymphoma and other non-Hodgkin's lymphomas
Rita Yim, K. Wong, Yok-Lam Kwong, F. Loong +6 more
2014OncoTarget29 citations Open access
Semantic Scholar
Small Biopsies Misclassify up to 35% of PD-L1 Assessments in Advanced Lung Non–Small Cell Lung Carcinomas
G. Bigras, Simon Mairs, P. Swanson, D. Morel +2 more
2018Applied immunohistochemistry & molecular morphology (Print)28 citations
Semantic Scholar
High Myc expression and transcription activity underlies intra-tumoral heterogeneity in triple-negative breast cancer
N. Gupta, K. Jung, Chengsheng Wu, A. Alshareef +8 more
2017OncoTarget28 citations Open access
Semantic Scholar
Effective down-regulation of signal transducer and activator of transcription 3 (STAT3) by polyplexes of siRNA and lipid-substituted polyethyleneimine for sensitization of breast tumor cells to conventional chemotherapy.
Arash Falamarzian, H. M. Aliabadi, Ommoleila Molavi, J. Seubert +3 more
2013Journal of Biomedical Materials Research. Part A28 citations
Semantic Scholar
PDGFRα Regulates Follicular Cell Differentiation Driving Treatment Resistance and Disease Recurrence in Papillary Thyroid Cancer
A. Lopez-Campistrous, E. E. Adewuyi, M. Benesch, Yi M. Ko +10 more
2016EBioMedicine27 citations Open access
Semantic Scholar
YB-1 regulates Sox2 to coordinately sustain stemness and tumorigenic properties in a phenotypically distinct subset of breast cancer cells
K. Jung, Fang Wu, Peng Wang, Xiao-Xia Ye +2 more
2014BMC Cancer27 citations Open access
Semantic Scholar
Silibinin induces immunogenic cell death in cancer cells and enhances the induced immunogenicity by chemotherapy
S. Jafari, Saba Heydarian, R. Lai, Elnaz Mehdizadeh Aghdam +1 more
2022BioImpacts26 citations Open access
Semantic Scholar
Oxidative stress enhances tumorigenicity and stem-like features via the activation of the Wnt/β-catenin/MYC/Sox2 axis in ALK-positive anaplastic large-cell lymphoma
Chengsheng Wu, N. Gupta, Yung-Hsing Huang, Hai-Feng Zhang +3 more
2018BMC Cancer26 citations Open access
Semantic Scholar
Oxidative stress induces the acquisition of cancer stem-like phenotype in breast cancer detectable by using a Sox2 regulatory region-2 (SRR2) reporter
K. Gopal, N. Gupta, Hai-Feng Zhang, A. Alshareef +7 more
2015OncoTarget25 citations Open access
Semantic Scholar
Germline DNA Copy Number Aberrations Identified as Potential Prognostic Factors for Breast Cancer Recurrence
Y. Sapkota, Sunita Ghosh, R. Lai, Bradley P. Coe +4 more
2013PLoS ONE25 citations Open access
Semantic Scholar
The pathobiology of the oncogenic tyrosine kinase NPM-ALK: a brief update
R. Lai, R. Ingham
2013Therapeutic Advances in Hematology25 citations Open access
Semantic Scholar
Constitutive Activation of STAT3 in Myeloma Cells Cultured in a Three-Dimensional, Reconstructed Bone Marrow Model
Yung-Hsing Huang, Ommoleila Molavi, Abdularaheem Alshareef, M. Haque +7 more
2018Cancers23 citations Open access
Semantic Scholar
STAT1β enhances STAT1 function by protecting STAT1α from degradation in esophageal squamous cell carcinoma
Ying Zhang, Yelong Chen, Hailong Yun, Zhaoyong Liu +2 more
2017Cell Death and Disease23 citations Open access
Semantic Scholar
Recent advances in cancer immunotherapy: Modulation of tumor microenvironment by Toll-like receptor ligands
Leila Rostamizadeh, Ommoleila Molavi, Mohsen Rashid, F. Ramazani +3 more
2022BioImpacts22 citations Open access
Semantic Scholar
Functionalized Caprolactone-Polyethylene Glycol Based Thermo-Responsive Hydrogels of Silibinin for the Treatment of Malignant Melanoma.
B. Makhmalzadeh, Ommoleila Molavi, M. Vakili, Hai-Feng Zhang +5 more
2018Journal of Pharmacy & Pharmaceutical Sciences22 citations Open access
Semantic Scholar
Triple negative breast cancers comprise a highly tumorigenic cell subpopulation detectable by its high responsiveness to a Sox2 regulatory region 2 (SRR2) reporter
K. Jung, N. Gupta, Peng Wang, J. Lewis +8 more
2015OncoTarget21 citations Open access
Semantic Scholar
Profiling gene promoter occupancy of Sox2 in two phenotypically distinct breast cancer cell subsets using chromatin immunoprecipitation and genome-wide promoter microarrays
K. Jung, Peng Wang, N. Gupta, K. Gopal +7 more
2014Breast Cancer Research21 citations Open access
Semantic Scholar
Micellar nano-carriers for the delivery of STAT3 dimerization inhibitors to melanoma
A. Soleimani, S. M. Garg, I. Paiva, M. Vakili +5 more
2017Drug Delivery and Translational Research17 citations
Semantic Scholar
Silibinin suppresses NPM-ALK, potently induces apoptosis and enhances chemosensitivity in ALK-positive anaplastic large cell lymphoma
Ommoleila Molavi, N. Samadi, Chengsheng Wu, A. Lavasanifar +1 more
2015Leukemia and Lymphoma17 citations
Semantic Scholar
Elevated ARG1 expression in primary monocytes-derived macrophages as a predictor of radiation-induced acute skin toxicities in early breast cancer patients
K. Jung, S. Sabri, J. Hanson, Yaoxian Xu +3 more
2015Cancer Biology & Therapy16 citations Open access
Semantic Scholar
Disheveled proteins promote cell growth and tumorigenicity in ALK-positive anaplastic large cell lymphoma.
Samar A. Hegazy, A. Alshareef, P. Gélébart, M. Anand +3 more
2013Cellular Signalling14 citations
Semantic Scholar
Phosphorylation of Sox2 at Threonine 116 is a Potential Marker to Identify a Subset of Breast Cancer Cells with High Tumorigenecity and Stem-Like Features
N. Gupta, K. Gopal, Chengsheng Wu, Abdularaheem Alshareef +6 more
2018Cancers13 citations Open access
Semantic Scholar
Enhancing bone marrow regeneration by SALL4 protein
Wenbin Liao, Jerell R. Aguila, Yi-Xin Yao, Jianchang Yang +8 more
2013Journal of Hematology & Oncology13 citations Open access
Semantic Scholar

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Ommoleila Molavi×13
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