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Thomas Kehrer · SciRah

Researcher profile · Semantic Scholar

Thomas Kehrer

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Thomas Kehrer — researcher profile on SciRah

h-index: 16
Works: 36
Citations: 2,620

Most-cited papers

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms
D. Gordon, J. Hiatt, Mehdi Bouhaddou, V. Rezelj +194 more
2020Science675 citations Open access
Semantic Scholar
SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling
Lisa Miorin, Thomas Kehrer, M. T. Sánchez-Aparicio, Ke Zhang +23 more
2020Proceedings of the National Academy of Sciences of the United States of America512 citations Open access
Semantic Scholar
Plitidepsin has potent preclinical efficacy against SARS-CoV-2 by targeting the host protein eEF1A
K. White, R. Rosales, S. Yıldız, Thomas Kehrer +22 more
2021Science290 citations Open access
Semantic Scholar
Nsp1 protein of SARS-CoV-2 disrupts the mRNA export machinery to inhibit host gene expression
Ke Zhang, Lisa Miorin, T. Makio, Ishmael Dehghan +15 more
2021Science Advances197 citations Open access
Semantic Scholar
Mutations in SARS-CoV-2 variants of concern link to increased spike cleavage and virus transmission
Alba Escalera, A. Gonzalez-Reiche, S. Aslam, I. Mena +25 more
2022Cell Host and Microbe160 citations Open access
Semantic Scholar
The N501Y mutation in SARS-CoV-2 spike leads to morbidity in obese and aged mice and is neutralized by convalescent and post-vaccination human sera
Raveen Rathnasinghe, S. Jangra, Anastasija Cupic, Carles Martínez-Romero +18 more
2021medRxiv117 citations Open access
Semantic Scholar
Contribution of SARS-CoV-2 Accessory Proteins to Viral Pathogenicity in K18 Human ACE2 Transgenic Mice
J. Silvas, Desarey Morales Vasquez, Jun-Gyu Park, Kevin Chiem +13 more
2021bioRxiv115 citations Open access
Semantic Scholar
SARS-CoV-2 variants evolve convergent strategies to remodel the host response
Mehdi Bouhaddou, Ann-Kathrin Reuschl, B. Polacco, Lucy G. Thorne +76 more
2023Cell96 citations Open access
Semantic Scholar
A household case evidences shorter shedding of SARS-CoV-2 in naturally infected cats compared to their human owners
V. Neira, B. Brito, B. Agüero, F. Berríos +18 more
2020medRxiv78 citations Open access
Semantic Scholar
Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis
Thomas Kehrer, Anastasija Cupic, C. Ye, S. Yıldız +36 more
2022bioRxiv72 citations Open access
Semantic Scholar
Hepatitis C virus drugs that inhibit SARS-CoV-2 papain-like protease synergize with remdesivir to suppress viral replication in cell culture
Khushboo Bafna, K. White, B. Harish, R. Rosales +9 more
2021Cell Reports68 citations Open access
Semantic Scholar
HIV protease cleaves the antiviral m6A reader protein YTHDF3 in the viral particle
D. Jurczyszak, Wen Zhang, S. Terry, Thomas Kehrer +6 more
2020PLoS Pathogens50 citations Open access
Semantic Scholar
Characterization of SARS-CoV-2 Spike mutations important for infection of mice and escape from human immune sera
Raveen Rathnasinghe, S. Jangra, C. Ye, Anastasija Cupic +43 more
2022Nature Communications46 citations Open access
Semantic Scholar
SARS-CoV-2 viral protein ORF3A injures renal tubules by interacting with TRIM59 to induce STAT3 activation
Hong Cai, Ya Chen, Ye Feng, M. Asadi +11 more
2022Molecular Therapy22 citations Open access
Semantic Scholar
Discovery and Intranasal Administration of a SARS-CoV-2 Broadly-Acting Neutralizing Antibody with Activity against multiple Omicron sub variants
J. A. Duty, T. Kraus, He-Yue Zhou, Yanliang Zhang +45 more
2022i Medicina17 citations Open access
Semantic Scholar
Interferon mediated prophylactic protection against respiratory viruses conferred by a prototype live attenuated influenza virus vaccine lacking non-structural protein 1
Raveen Rathnasinghe, M. Salvatore, Hong-Yong Zheng, S. Jangra +6 more
2021Scientific Reports17 citations Open access
Semantic Scholar
Functional Effects of Cardiomyocyte Injury in COVID-19
Mustafa M. Siddiq, A. Chan, Lisa Miorin, A. S. Yadaw +29 more
2021Journal of Virology15 citations Open access
Semantic Scholar
The oral drug nitazoxanide restricts SARS-CoV-2 infection and attenuates disease pathogenesis in Syrian hamsters
Lisa Miorin, C. Mire, S. Ranjbar, A. Hume +31 more
2022bioRxiv13 citations Open access
Semantic Scholar
Global landscape of the host response to SARS-CoV-2 variants reveals viral evolutionary trajectories
Mehdi Bouhaddou, Ann-Kathrin Reuschl, B. Polacco, Lucy G. Thorne +73 more
2022bioRxiv13 citations Open access
Semantic Scholar
The IRE1α-XBP1 arm of the unfolded protein response is a host factor activated in SARS-CoV-2 infection
J. J. Fernández, Arturo Marin, R. Rosales, Rebekah Penrice-Randal +27 more
2024Biochimica et Biophysica Acta - Molecular Basis of Disease11 citations Open access
Semantic Scholar
SARS-CoV-2 variants of concern have acquired mutations associated with an 1 increased spike cleavage 2
Alba Escalera, A. Gonzalez-Reiche, S. Aslam, I. Mena +21 more
202111 citations
Semantic Scholar
Physiology of cardiomyocyte injury in COVID-19
Mustafa M. Siddiq, A. Chan, Lisa Miorin, A. S. Yadaw +26 more
2020medRxiv11 citations Open access
Semantic Scholar
Control of Innate Immune Activation by Severe Acute Respiratory Syndrome Coronavirus 2 and Other Coronaviruses
Thomas Kehrer, A. García-Sastre, Lisa Miorin
2021Journal of Interferon and Cytokine Research8 citations Open access
Semantic Scholar
Unambiguous detection of SARS-CoV-2 subgenomic mRNAs with single-cell RNA sequencing
Phillip Cohen, Emma J. DeGrace, Oded Danziger, Roosheel S. Patel +7 more
2021bioRxiv8 citations Open access
Semantic Scholar
Hepatitis C Virus Drugs Simeprevir and Grazoprevir Synergize with Remdesivir to Suppress SARS-CoV-2 Replication in Cell Culture
Khushboo Bafna, K. White, B. Harish, R. Rosales +9 more
20208 citations Open access
Semantic Scholar
SARS-CoV-2 variants of concern have acquired mutations associated with an increased spike cleavage
Alba Escalera, A. Gonzalez-Reiche, S. Aslam, I. Mena +21 more
2021bioRxiv6 citations Open access
Semantic Scholar
Discovery of a SARS-CoV-2 Broadly-Acting Neutralizing Antibody with Activity against Omicron and Omicron + R346K Variants
J. A. Duty, T. Kraus, He-Yue Zhou, Yanliang Zhang +44 more
2022bioRxiv5 citations Open access
Semantic Scholar
Coronavirus Protein Interaction Mapping in Bat and Human Cells Reveals Network Rewiring Governing Immune-Evasion and Zoonotic Potential
Jyoti Batra, Magdalena Rutkowska, Yuan Zhou, C. Ye +60 more
2026Cell Host and Microbe2 citations Open access
Semantic Scholar
Coronavirus protein interaction mapping in bat and human cells identifies molecular and genetic switches for immune evasion and replication
Jyoti Batra, Magdalena Rutkowska, Yuan Zhou, C. Ye +53 more
2025bioRxiv2 citations Open access
Semantic Scholar
Prophylactic protection against respiratory viruses conferred by a prototype live attenuated influenza virus vaccine.
Raveen Rathnasinghe, M. Salvatore, Hong-Yong Zheng, S. Jangra +6 more
2021bioRxiv2 citations Open access
Semantic Scholar
Liquid Biopsy-Multiomics Link Adhesion Pathway Dysregulation to Kidney Injury Severity
N. Anandakrishnan, Zheng-Zi Yi, Ze-Guo Sun, Tong Liu +34 more
2025Kidney International Reports1 citations Open access
Semantic Scholar
Integrated multiomics implicates dysregulation of ECM and cell adhesion pathways as drivers of severe COVID-associated kidney injury
N. Anandakrishnan, Zheng-Zi Yi, Ze-Guo Sun, Tong Liu +34 more
2024medRxiv1 citations Open access
Semantic Scholar
3016-LB: Overexpression of Immune Inhibitory Ligand B7-H4, Not PD-L1, on Pancreatic Beta Cells Confer Resistance to Type 1 Diabetes in NOD Mice
Orr-El Weizman, Qi Su, R. Bucktrout, B. Sung +11 more
2026Diabetes0 citations
Semantic Scholar
Structure function characterization of SARS CoV2 proteases for COVID19 antiviral development
Rebecca Greene-Cramer, Khushboo Bafna, K. White, B. Harish +10 more
2022Biophysical Journal0 citations Open access
Semantic Scholar
Hepatitis C Virus Drugs Simeprevir And Grazoprevir Synergize with Remdesivir to Suppress SARS-CoV2 Replication
Khushboo Bafna, K. White, H. Balasubramanian, R. Rosales +9 more
2020Social Science Research Network0 citations Open access
Semantic Scholar
Organizational Procedures for the Integration of Process Planning and Scheduling in Job-Shop Manufacturing
S. Häckel, J. Keidel, Thomas Kehrer
20130 citations
Semantic Scholar

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