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M. Vankemmelbeke · SciRah

Researcher profile · Semantic Scholar

M. Vankemmelbeke

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M. Vankemmelbeke — researcher profile on SciRah

h-index: 18
Works: 46
Citations: 1,008

Most-cited papers

Expression and activity of ADAMTS-5 in synovium.
M. Vankemmelbeke, I. Holen, A. Wilson, M. Ilic +7 more
2001European Journal of Biochemistry123 citations
Semantic Scholar
Cleavage of cartilage oligomeric matrix protein (thrombospondin-5) by matrix metalloproteinases and a disintegrin and metalloproteinase with thrombospondin motifs.
S. Dickinson, M. Vankemmelbeke, D. Buttle, Krisztina Rosenberg +2 more
2003Matrix Biology104 citations
Semantic Scholar
Allosteric β‐propeller signalling in TolB and its manipulation by translocating colicins
D. Bonsor, Oliver Hecht, M. Vankemmelbeke, Amit Sharma +6 more
2009EMBO Journal88 citations Open access
Semantic Scholar
Differential expression patterns of matrix metalloproteinases and their inhibitors during development of osteoarthritis in a transgenic mouse model
H. Salminen, A. Säämänen, M. Vankemmelbeke, P. K. Auho +2 more
2002Annals of the Rheumatic Diseases69 citations Open access
Semantic Scholar
The Role of Electrostatics in Colicin Nuclease Domain Translocation into Bacterial Cells*
D. Walker, K. Mosbahi, M. Vankemmelbeke, R. James +1 more
2007Journal of Biological Chemistry59 citations Open access
Semantic Scholar
Third-generation antibody drug conjugates for cancer therapy--a balancing act.
M. Vankemmelbeke, L. Durrant
2016Therapeutic delivery54 citations Open access
Semantic Scholar
Post-translational modifications such as citrullination are excellent targets for cancer therapy.
Victoria A Brentville, M. Vankemmelbeke, R. Metheringham, L. Durrant
2020Seminars in Immunology52 citations Open access
Semantic Scholar
Energy-dependent Immunity Protein Release during tol-dependent Nuclease Colicin Translocation
M. Vankemmelbeke, Ying Zhang, G. Moore, C. Kleanthous +2 more
2009Journal of Biological Chemistry49 citations Open access
Semantic Scholar
ADAMTS9-Regulated Pericellular Matrix Dynamics Governs Focal Adhesion-Dependent Smooth Muscle Differentiation
T. Mead, Yaoyao Du, Courtney M. Nelson, Ndeye-Aicha Gueye +5 more
2018Cell Reports47 citations Open access
Semantic Scholar
Rapid Detection of Colicin E9-Induced DNA Damage Using Escherichia coli Cells Carrying SOS Promoter-lux Fusions
M. Vankemmelbeke, B. Healy, G. Moore, C. Kleanthous +2 more
2005Journal of Bacteriology31 citations Open access
Semantic Scholar
Flexibility in the Receptor-Binding Domain of the Enzymatic Colicin E9 Is Required for Toxicity against Escherichia coli Cells
Christopher N. Penfold, B. Healy, N. G. Housden, R. Boetzel +4 more
2004Journal of Bacteriology31 citations Open access
Semantic Scholar
Interactions of TolB with the Translocation Domain of Colicin E9 Require an Extended TolB Box
S. Hands, L. Holland, M. Vankemmelbeke, L. Fraser +4 more
2005Journal of Bacteriology26 citations Open access
Semantic Scholar
Monoclonal Antibody Targeting Sialyl-di-Lewisa–Containing Internalizing and Noninternalizing Glycoproteins with Cancer Immunotherapy Development Potential
Silvana T Tivadar, R. Mcintosh, Xin-Chua Jia, Robert S. Moss +5 more
2019Molecular Cancer Therapeutics24 citations Open access
Semantic Scholar
Monoclonal Antibodies Targeting LecLex-Related Glycans with Potent Antitumor Activity
Xin-Chua Jia, M. Vankemmelbeke, R. Mcintosh, P. Clarke +6 more
2015Clinical Cancer Research23 citations Open access
Semantic Scholar
Structural Evidence That Colicin A Protein Binds to a Novel Binding Site of TolA Protein in Escherichia coli Periplasm
Chan Li, Ying Zhang, M. Vankemmelbeke, Oliver Hecht +5 more
2012Journal of Biological Chemistry23 citations Open access
Semantic Scholar
Design of a polypeptide FRET substrate that facilitates study of the antimicrobial protease lysostaphin.
P. Bardelang, M. Vankemmelbeke, Ying Zhang, H. Jarvis +5 more
2009Biochemical Journal23 citations Open access
Semantic Scholar
The crystal structure of the TolB box of colicin A in complex with TolB reveals important differences in the recruitment of the common TolB translocation portal used by group A colicins
Ying Zhang, Chan Li, M. Vankemmelbeke, P. Bardelang +3 more
2009Molecular Microbiology22 citations Open access
Semantic Scholar
Targeting Glycans and Heavily Glycosylated Proteins for Tumor Imaging
R. Houvast, M. Vankemmelbeke, L. Durrant, M. Wuhrer +5 more
2020Cancers19 citations Open access
Semantic Scholar
Investigating Early Events in Receptor Binding and Translocation of Colicin E9 Using Synchronized Cell Killing and Proteolytic Cleavage
Ying Zhang, M. Vankemmelbeke, L. Holland, D. Walker +2 more
2008Journal of Bacteriology17 citations Open access
Semantic Scholar
The terminal sialic acid of stage-specific embryonic antigen-4 has a crucial role in binding to a cancer-targeting antibody
C. Soliman, Xin-Chua Jia, M. Vankemmelbeke, R. Mcintosh +4 more
2019Journal of Biological Chemistry15 citations Open access
Semantic Scholar
Glycan-Based Near-infrared Fluorescent (NIRF) Imaging of Gastrointestinal Tumors: a Preclinical Proof-of-Concept In Vivo Study
R. Houvast, V. Baart, S. Bhairosingh, R. Cordfunke +7 more
2020Molecular Imaging and Biology14 citations Open access
Semantic Scholar
Cancer cell associated glycans as targets for immunotherapy
M. Vankemmelbeke, Xin-Chua Jia, L. Durrant
2015Oncoimmunology13 citations Open access
Semantic Scholar
Immunity protein release from a cell-bound nuclease colicin complex requires global conformational rearrangement
M. Vankemmelbeke, N. G. Housden, R. James, C. Kleanthous +1 more
2013MicrobiologyOpen11 citations Open access
Semantic Scholar
Colicin A binds to a novel binding site of TolA in the Escherichia coli periplasm.
Christopher N. Penfold, Chan Li, Ying Zhang, M. Vankemmelbeke +1 more
2012Biochemical Society Transactions10 citations
Semantic Scholar
An Immunohistochemical Evaluation of Tumor-Associated Glycans and Mucins as Targets for Molecular Imaging of Pancreatic Ductal Adenocarcinoma
R. Houvast, Kira Thijse, J. Groen, J. Chua +8 more
2021Cancers9 citations Open access
Semantic Scholar
Engineering the human Fc-region enables direct cell killing by cancer glycan-targeting antibodies without the need for immune effector cells or complement
M. Vankemmelbeke, R. Mcintosh, Xin-Chua Jia, Thomas Kirk +9 more
2020Cancer Research9 citations Open access
Semantic Scholar
Interaction of Nuclease Colicins with Membranes: Insertion Depth Correlates with Bilayer Perturbation
M. Vankemmelbeke, P. O'Shea, R. James, Christopher N. Penfold
2012PLoS ONE7 citations Open access
Semantic Scholar
Prediction of Biomarker Expression on Primary Pancreatic Ductal Adenocarcinoma Tissues Using Fine-Needle Biopsies: Paving the Way for a Patient-Tailored Molecular Imaging Approach
R. Houvast, M. van Duijvenvoorde, J. Chua, M. Vankemmelbeke +9 more
2023Molecular Diagnosis & Therapy5 citations Open access
Semantic Scholar
A novel bivalent DNA vaccine encoding both spike protein receptor-binding domain and nucleocapsid protein of SARS-CoV-2 to elicit T cell and neutralising antibody responses that cross react with variants
VA Brentville, M. Vankemmelbeke, RL Metheringham, P. Symonds +16 more
20215 citations Open access
Semantic Scholar
Detection of induced synthesis of colicin E9 using ColE9p::gfpmut2 based reporter system
S. Bano, M. Vankemmelbeke, Christopher N. Penfold, R. James
2014World Journal of Microbiology & Biotechnology5 citations
Semantic Scholar
Pattern of induction of colicin E9 synthesis by sub MIC of Norfloxacin antibiotic.
S. Bano, M. Vankemmelbeke, Christopher N. Penfold, R. James
2013Microbiology Research5 citations Open access
Semantic Scholar
Molecular and structural basis for Lewis glycan recognition by a cancer-targeting antibody.
C. Soliman, Andrew J. Guy, Xin-Chua Jia, M. Vankemmelbeke +7 more
2020Biochemical Journal4 citations Open access
Semantic Scholar
Membrane activities of colicin nuclease domains: analogies with antimicrobial peptides.
M. Vankemmelbeke, R. James, Christopher N. Penfold
2012Biochemical Society Transactions3 citations
Semantic Scholar
SARS-CoV-2 spike RBD and nucleocapsid encoding DNA vaccine elicits T cell and neutralising antibody responses that cross react with variants
VA Brentville, M. Vankemmelbeke, RL Metheringham, P. Symonds +20 more
2023bioRxiv2 citations Open access
Semantic Scholar
COMPLETE NUCLEOTIDE SEQUENCING AND MOLECULAR CHARACTERIZATION OF THE PCOLE9-J PLASMID
S. Bano, M. Vankemmelbeke, S. A. Tunio, Christopher N. Penfold +1 more
20122 citations
Semantic Scholar
Rapid Detection of Colicin E9-Induced DNA Damage Using Escherichia coli Cells Carrying SOS Promoter-lux Fusions
M. Vankemmelbeke, B. Healy, G. Moore, C. Kleanthous +2 more
20052 citations Open access
Semantic Scholar
Heterogeneity in the spontaneous induction of the promoter of the ColE9 operon in Escherichia coli
S. Bano, M. Vankemmelbeke, Christopher N. Penfold, S. A. Tunio +1 more
2022Archives of Microbiology1 citations
Semantic Scholar
Expression of recombinant ADAMTS in insect cells.
Gavin C. Jones, M. Vankemmelbeke, D. Buttle
2010Methods in molecular biology1 citations
Semantic Scholar
Erratum: Allosteric β-propeller signalling in TolB and its manipulation by translocating colicins (EMBO Journal (2009) DOI: 10.1038/emboj.2009.224)
D. Bonsor, Oliver Hecht, M. Vankemmelbeke, Amit Sharma +6 more
20091 citations Open access
Semantic Scholar
Abstract A161: Targeting gastrointestinal tumors with constant region engineered anti-glycan antibodies
M. Vankemmelbeke, Thomas Kirk, J. Chua, R. Mcintosh +1 more
2019Maintenance of Immune Balance: Effects of Targeted and Immune Therapies0 citations
Semantic Scholar
Vankemmelbeke, Mireille and Housden, Nicholas G. and James, Richard and Kleanthous, Colin and Penfold, Christopher N. (2013) Immunity protein release from a cell-bound nuclease colicin complex requires global
M. Vankemmelbeke, N. G. Housden, R. James, C. Kleanthous +1 more
20160 citations
Semantic Scholar
Monoclonal Antibodies Targeting Le c Le x -Related Glycans with Potent Anti-Tumor Activity activity of
J. Chua, M. Vankemmelbeke, R. Mcintosh, P. Clarke +7 more
20150 citations
Semantic Scholar
Detection of induced synthesis of colicin E9 using ColE9p::gfpmut2 based reporter system
S. Bano, M. Vankemmelbeke, Christopher N. Penfold, R. James
2014World Journal of Microbiology & Biotechnology0 citations
Semantic Scholar
Allosteric β‐propeller signalling in TolB and its manipulation by translocating colicins
D. Bonsor, Oliver Hecht, M. Vankemmelbeke, Amit Sharma +6 more
20090 citations Open access
Semantic Scholar
and Colin Cells The Role of Electrostatics in Colicin Nuclease Domain Translocation into Bacterial
D. Walker, K. Mosbahi, M. Vankemmelbeke, R. James +1 more
20070 citations
Semantic Scholar
Inhibition of adamts-1, -4 and 5 by catecin esters
M. Vankemmelbeke, M. Ilic, Gavin C. Jones, C. Handley +3 more
20020 citations
Semantic Scholar

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R. James×24
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Christopher N. Penfold×19
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L. Durrant×14
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C. Kleanthous×11
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Xin-Chua Jia×7

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Ying Zhang — researcher profile on SciRah

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S. Bano — researcher profile on SciRah

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