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Yang-Chun Xie · SciRah

Researcher profile · Semantic Scholar

Yang-Chun Xie

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Yang-Chun Xie — researcher profile on SciRah

h-index: 33
Works: 60
Citations: 10K

Most-cited papers

Autophagy promotes ferroptosis by degradation of ferritin
W. Hou, Yang-Chun Xie, Xin-Xin Song, Xiao-Fang Sun +4 more
2016Autophagy2,141 citations Open access
Semantic Scholar
The Tumor Suppressor p53 Limits Ferroptosis by Blocking DPP4 Activity.
Yang-Chun Xie, Shan Zhu, Xin-Xin Song, Xiao-Fang Sun +11 more
2017Cell Reports860 citations Open access
Semantic Scholar
AMPK-mediated BECN1 phosphorylation Promotes Ferroptosis by Directly Blocking System Xc− Activity
Xin-Xin Song, Shan Zhu, Pan Chen, Wen Hou +10 more
2018Current Biology696 citations Open access
Semantic Scholar
GPX4 in cell death, autophagy, and disease
Yang-Chun Xie, Rui Kang, D. Klionsky, D. Tang
2023Autophagy610 citations Open access
Semantic Scholar
Autophagy-dependent ferroptosis drives tumor-associated macrophage polarization via release and uptake of oncogenic KRAS protein
En-Yong Dai, Leng Han, Jiao Liu, Yang-Chun Xie +6 more
2020Autophagy580 citations Open access
Semantic Scholar
Lipid Peroxidation Drives Gasdermin D-mediated Pyroptosis in Lethal Polymicrobial Sepsis
R. Kang, L. Zeng, Shan Zhu, Yang-Chun Xie +10 more
2018Cell Host and Microbe557 citations Open access
Semantic Scholar
The ferroptosis inducer erastin enhances sensitivity of acute myeloid leukemia cells to chemotherapeutic agents
Yan Yu, Yang-Chun Xie, Lizhi Cao, Liang-Chun Yang +5 more
2015Molecular & Cellular Oncology444 citations Open access
Semantic Scholar
Ferroptotic damage promotes pancreatic tumorigenesis through a TMEM173/STING-dependent DNA sensor pathway
En-Yong Dai, Leng Han, Jiao Liu, Yang-Chun Xie +4 more
2020Nature Communications393 citations Open access
Semantic Scholar
Posttranslational modification of autophagy-related proteins in macroautophagy
Yang-Chun Xie, R. Kang, Xiao-Fang Sun, M. Zhong +3 more
2015Autophagy303 citations Open access
Semantic Scholar
A guideline on the molecular ecosystem regulating ferroptosis
En-Yong Dai, Xin Chen, A. Linkermann, Xue-Jun Jiang +44 more
2024Nature Cell Biology284 citations
Semantic Scholar
NUPR1 is a critical repressor of ferroptosis
Jiao Liu, Xin-Xin Song, Fei-Mei Kuang, Qiuhong Zhang +4 more
2021Nature Communications254 citations Open access
Semantic Scholar
PINK1 and PARK2 Suppress Pancreatic Tumorigenesis through Control of Mitochondrial Iron-mediated Immunometabolism
Chang-Feng Li, Ying Zhang, Xing Cheng, Hua Yuan +11 more
2018Developmental Cell244 citations Open access
Semantic Scholar
Identification of baicalein as a ferroptosis inhibitor by natural product library screening.
Yang-Chun Xie, Xin-Xin Song, Xiao-Fang Sun, Jin Huang +5 more
2016Biochemical and Biophysical Research Communications - BBRC231 citations
Semantic Scholar
PDK4 dictates metabolic resistance to ferroptosis by suppressing pyruvate oxidation and fatty acid synthesis.
Xin-Xin Song, Jiao Liu, Fei-Mei Kuang, Xin Chen +5 more
2021Cell Reports228 citations Open access
Semantic Scholar
JTC801 Induces pH-dependent Death Specifically in Cancer Cells and Slows Growth of Tumors in Mice
Xin-Xin Song, Shan Zhu, Yang-Chun Xie, Jiao Liu +11 more
2017Gastroenterology224 citations Open access
Semantic Scholar
Interplay Between Lipid Metabolism and Autophagy
Yang-Chun Xie, Jingbo Li, R. Kang, D. Tang
2020Frontiers in Cell and Developmental Biology184 citations Open access
Semantic Scholar
TMEM164 is a new determinant of autophagy-dependent ferroptosis
Jiao Liu, Yang Liu, Yuanhong Wang, Chang-Feng Li +4 more
2022Autophagy181 citations Open access
Semantic Scholar
Inhibition of Aurora Kinase A Induces Necroptosis in Pancreatic Carcinoma
Yang-Chun Xie, Shan Zhu, M. Zhong, Ming-Hua Yang +7 more
2017Gastroenterology176 citations Open access
Semantic Scholar
MGST1 is a redox-sensitive repressor of ferroptosis in pancreatic cancer cells.
Fei-Mei Kuang, Jiao Liu, Yang-Chun Xie, D. Tang +1 more
2021Cell Chemical Biology175 citations Open access
Semantic Scholar
FANCD2 protects against bone marrow injury from ferroptosis
Xin-Xin Song, Yang-Chun Xie, R. Kang, W. Hou +4 more
2016Biochemical and Biophysical Research Communications - BBRC174 citations Open access
Semantic Scholar
DAMPs, Ageing, and Cancer: The ‘DAMP Hypothesis’
Jin Huang, Yang-Chun Xie, Xiao-Fang Sun, H. Zeh +3 more
2014Ageing Research Reviews142 citations Open access
Semantic Scholar
Intracellular HMGB1 as a novel tumor suppressor of pancreatic cancer
R. Kang, Yang-Chun Xie, Qiuhong Zhang, W. Hou +10 more
2017Cell Research136 citations Open access
Semantic Scholar
LncRNA NEAT1 Interacted With DNMT1 to Regulate Malignant Phenotype of Cancer Cell and Cytotoxic T Cell Infiltration via Epigenetic Inhibition of p53, cGAS, and STING in Lung Cancer
F. Ma, Y. Lei, Meng-Ge Ding, Li-Hua Luo +2 more
2020Frontiers in Genetics106 citations Open access
Semantic Scholar
A novel PINK1- and PARK2-dependent protective neuroimmune pathway in lethal sepsis
R. Kang, L. Zeng, Yang-Chun Xie, Zhengwen Yan +9 more
2016Autophagy96 citations Open access
Semantic Scholar
A noncanonical function of EIF4E limits ALDH1B1 activity and increases susceptibility to ferroptosis
Xin Chen, Jun Huang, Chunhua Yu, Jiao Liu +10 more
2022Nature Communications89 citations Open access
Semantic Scholar
Antiferroptotic activity of non-oxidative dopamine.
Ding Wang, Yingpeng Peng, Yang-Chun Xie, Bo-Rong Zhou +3 more
2016Biochemical and Biophysical Research Communications - BBRC82 citations
Semantic Scholar
NFE2L2 and SLC25A39 drive cuproptosis resistance through GSH metabolism
Jiao Liu, Hu Tang, Fangquan Chen, Chang-Feng Li +3 more
2024Scientific Reports67 citations Open access
Semantic Scholar
Mitophagy Receptors in Tumor Biology
Yang-Chun Xie, Jiao Liu, R. Kang, D. Tang
2020Frontiers in Cell and Developmental Biology61 citations Open access
Semantic Scholar
PYCR1 knockdown inhibits the proliferation, migration, and invasion by affecting JAK/STAT signaling pathway in lung adenocarcinoma
Ya-Wen Gao, Li-Hua Luo, Yang-Chun Xie, Yu Zhao +2 more
2020Molecular Carcinogenesis61 citations
Semantic Scholar
Mitochondrial quality control mediated by PINK1 and PRKN: links to iron metabolism and tumor immunity
R. Kang, Yang-Chun Xie, H. Zeh, D. Klionsky +1 more
2018Autophagy57 citations Open access
Semantic Scholar
Extracellular GPX4 impairs antitumor immunity via dendritic ZP3 receptors.
Jiao Liu, Xiutao Cai, Junhao Lin, Zhenhui Zhang +14 more
2026Cell56 citations
Semantic Scholar
Macroautophagy/autophagy promotes resistance to KRASG12D-targeted therapy through glutathione synthesis
Leng Han, Ling-Jun Meng, Jiao Liu, Yang-Chun Xie +5 more
2024Cancer Letters34 citations Open access
Semantic Scholar
DUSP1 Blocks autophagy-dependent ferroptosis in pancreatic cancer
Yang-Chun Xie, Fei-Mei Kuang, Jiao Liu, D. Tang +1 more
202034 citations Open access
Semantic Scholar
AGER-dependent macropinocytosis drives resistance to KRAS-G12D-targeted therapy in advanced pancreatic cancer.
Chang-Feng Li, Yuan-Da Liu, Chang Liu, Fangquan Chen +6 more
2025Science Translational Medicine31 citations
Semantic Scholar
The microRNA-130a-5p/RUNX2/STK32A network modulates tumor invasive and metastatic potential in non-small cell lung cancer
F. Ma, Yang-Chun Xie, Y. Lei, Zengshuyu Kuang +1 more
2020BMC Cancer27 citations Open access
Semantic Scholar
Sp1-induced upregulation of the long noncoding RNA TINCR inhibits cell migration and invasion by regulating miR-107/miR-1286 in lung adenocarcinoma.
Ya-Wen Gao, F. Ma, Yang-Chun Xie, Meng-Ge Ding +4 more
2019American journal of translational research26 citations
Semantic Scholar
Mitophagy in Pancreatic Cancer
Yang-Chun Xie, Jiao Liu, R. Kang, D. Tang
2021Frontiers in Oncology24 citations Open access
Semantic Scholar
Novel chemokine-like activities of histones in tumor metastasis
Ruochan Chen, Yang-Chun Xie, Xiao Zhong, Yongming Fu +11 more
2016OncoTarget19 citations Open access
Semantic Scholar
The Role of the SOX9/lncRNA ANXA2P2/miR-361-3p/SOX9 Regulatory Loop in Cervical Cancer Cell Growth and Resistance to Cisplatin
Shasha He, Ye-Qian Feng, Wen Zou, Jing-Jing Wang +5 more
2022Frontiers in Oncology18 citations Open access
Semantic Scholar
Autophagy-dependent ferroptosis as a potential treatment for glioblastoma
Yang-Chun Xie, T. Hou, Jinyou Liu, Haixia Zhang +3 more
2023Frontiers in Oncology15 citations Open access
Semantic Scholar
Adjuvant therapy for resected EGFR-mutant non-small-cell lung cancer.
Jin-An Ma, Shun-Yuan Jiang, Chun-Hong Hu, Yang-Chun Xie +1 more
2018The Lancet Oncology13 citations Open access
Semantic Scholar
High fibrinogen-albumin ratio index (FARI) predicts poor survival in head and neck squamous cell carcinoma patients treated with surgical resection
Si-Si Wang, Yu-Hua Feng, Yang-Chun Xie, Xiayan Zhao +4 more
2022European Archives of Oto-Rhino-Laryngology12 citations
Semantic Scholar
Alpha Thalassemia/Intellectual Disability X-Linked Deficiency Sensitizes Non-Small Cell Lung Cancer to Immune Checkpoint Inhibitors
Tao Hou, Shun-Yuan Jiang, Yapeng Wang, Yang-Chun Xie +6 more
2020Frontiers in Oncology11 citations Open access
Semantic Scholar
[Effect of TUBB3, TS and ERCC1 mRNA expression on chemoresponse and clinical outcome of advanced gastric cancer by multiplex branched-DNA liquid chip technology].
Jin Huang, Hua-Bin Hu, Yang-Chun Xie, You-Hong Tang +2 more
2013Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences9 citations
Semantic Scholar
Role of the Beclin 1 Network in the Cross-Regulation Between Autophagy and Apoptosis
Yang-Chun Xie, R. Kang, D. Tang
20167 citations
Semantic Scholar
Lower Expression of TWEAK is Associated with Poor Survival and Dysregulate TIICs in Lung Adenocarcinoma
Zheng-Xi He, Sai Wang, Jinchun Wu, Yang-Chun Xie +1 more
2022Disease Markers6 citations Open access
Semantic Scholar
Clinicopathological Significance of ATRX Expression in Nasopharyngeal Carcinoma Patients: A Retrospective Study
Yang-Chun Xie, Haihua Wang, Si-Si Wang, Yu-Hua Feng +5 more
2021Journal of Cancer5 citations Open access
Semantic Scholar
Assessment of Posttranslational Modifications of ATG proteins.
Yang-Chun Xie, Rui Kang, D. Tang
2017Methods in Enzymology5 citations
Semantic Scholar
Male breast cancer arising in ectopic axillary breast tissue: A diagnostic dilemma
Yang-Chun Xie, Jin Huang, D. Xiao, M. Zhong
2013Oncology Letters4 citations Open access
Semantic Scholar
The Flavone Baicalein and Its Use in Gastrointestinal Disease
Yang-Chun Xie, R. Kang, D. Tang
2019Dietary Interventions in Liver Disease3 citations
Semantic Scholar

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