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K. Slep · SciRah

Researcher profile · Semantic Scholar

K. Slep

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K. Slep — researcher profile on SciRah

h-index: 25
Works: 74
Citations: 2,524

Most-cited papers

Structural basis of microtubule plus end tracking by XMAP215, CLIP-170, and EB1.
K. Slep, R. Vale
2007Molecules and Cells276 citations Open access
Semantic Scholar
The Drosophila afadin homologue Canoe regulates linkage of the actin cytoskeleton to adherens junctions during apical constriction
Jessica K. Sawyer, Nathan J. Harris, K. Slep, U. Gaul +1 more
2009Journal of Cell Biology269 citations Open access
Semantic Scholar
Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 Å
K. Slep, M. A. Kercher, Wei He, C. W. Cowan +2 more
2001Nature262 citations
Semantic Scholar
Structural determinants for EB1-mediated recruitment of APC and spectraplakins to the microtubule plus end
K. Slep, S. Rogers, Sarah L. Elliott, H. Ohkura +2 more
2005Journal of Cell Biology205 citations Open access
Semantic Scholar
Sst2 is a GTPase-activating protein for Gpa1: purification and characterization of a cognate RGS-Galpha protein pair in yeast.
D. Apanovitch, K. Slep, P. Sigler, H. Dohlman
1998Biochemistry135 citations
Semantic Scholar
Prediction and confirmation of a site critical for effector regulation of RGS domain activity
M. Sowa, Wei He, K. Slep, M. A. Kercher +2 more
2001Nature Structural Biology127 citations
Semantic Scholar
The Spectraplakin Short Stop Is an Actin–Microtubule Cross-Linker That Contributes to Organization of the Microtubule Network
Derek A. Applewhite, Kyle D. Grode, D. Keller, A. Zadeh +2 more
2010Molecular Biology of the Cell110 citations Open access
Semantic Scholar
The Structure of the Plk4 Cryptic Polo Box Reveals Two Tandem Polo Boxes Required for Centriole Duplication
Lauren K. Slevin, J. Nye, Derek C Pinkerton, D. Buster +2 more
2012Structure93 citations Open access
Semantic Scholar
Structural and mechanistic insights into microtubule end-binding proteins.
K. Slep
2010Current Opinion in Cell Biology83 citations
Semantic Scholar
Modules in the Photoreceptor RGS9-1·Gβ 5L GTPase-accelerating Protein Complex Control Effector Coupling, GTPase Acceleration, Protein Folding, and Stability*
W. He, Li-Sha Lu, Xue Zhang, H. El-Hodiri +5 more
2000Journal of Biological Chemistry82 citations Open access
Semantic Scholar
The role of TOG domains in microtubule plus end dynamics.
K. Slep
2009Biochemical Society Transactions65 citations
Semantic Scholar
A centrosome interactome provides insight into organelle assembly and reveals a non-duplication role for Plk4
B. Galletta, C. Fagerstrom, T. A. Schoborg, Tiffany A McLamarrah +5 more
2016Nature Communications60 citations Open access
Semantic Scholar
Molecular architecture of Gαo and the structural basis for RGS16-mediated deactivation
K. Slep, M. A. Kercher, T. Wieland, C. Chen +2 more
2008Proceedings of the National Academy of Sciences of the United States of America59 citations Open access
Semantic Scholar
A Cryptic TOG Domain with a Distinct Architecture Underlies CLASP- Dependent Bipolar Spindle Formation
J. Leano, S. Rogers, K. Slep
2013Structure58 citations Open access
Semantic Scholar
Crescerin uses a TOG domain array to regulate microtubules in the primary cilium
Alakananda Das, D. Dickinson, C. C. Wood, B. Goldstein +1 more
2015Molecular Biology of the Cell55 citations Open access
Semantic Scholar
The XMAP215 family drives microtubule polymerization using a structurally diverse TOG array
J. C. Fox, A. E. Howard, J. Currie, S. Rogers +1 more
2014Molecular Biology of the Cell53 citations Open access
Semantic Scholar
An ordered pattern of Ana2 phosphorylation by Plk4 is required for centriole assembly
Tiffany A McLamarrah, D. Buster, B. Galletta, Cody J. Boese +7 more
2017bioRxiv50 citations Open access
Semantic Scholar
TOG–tubulin binding specificity promotes microtubule dynamics and mitotic spindle formation
A. E. Byrnes, K. Slep
2017Journal of Cell Biology50 citations Open access
Semantic Scholar
The microtubule lattice and plus-end association of Drosophila Mini spindles is spatially regulated to fine-tune microtubule dynamics
J. Currie, Shannon F. Stewman, Gregory V. Schimizzi, K. Slep +2 more
2011Molecular Biology of the Cell44 citations Open access
Semantic Scholar
Two Polo-like kinase 4 binding domains in Asterless perform distinct roles in regulating kinase stability
Joseph E. Klebba, B. Galletta, J. Nye, K. M. Plevock +5 more
2015Journal of Cell Biology32 citations Open access
Semantic Scholar
The Mechanism of Dynein Light Chain LC8-mediated Oligomerization of the Ana2 Centriole Duplication Factor*
Lauren K. Slevin, Erin M. Romes, M. Dandulakis, K. Slep
2014Journal of Biological Chemistry30 citations Open access
Semantic Scholar
The yeast dynein Dyn2-Pac11 complex is a dynein dimerization/processivity factor: structural and single-molecule characterization
Lu Rao, Erin M. Romes, M. Nicholas, Sibylle Brenner +3 more
2013Molecular Biology of the Cell29 citations Open access
Semantic Scholar
Control of microtubule dynamics using an optogenetic microtubule plus end–F-actin cross-linker
Rebecca C. Adikes, R. Hallett, B. Saway, B. Kuhlman +1 more
2017bioRxiv26 citations Open access
Semantic Scholar
Multivalent interactions make adherens junction–cytoskeletal linkage robust during morphogenesis
Kia Z. Perez-Vale, Kristi D. Yow, Ruth I. Johnson, A. E. Byrnes +3 more
2021bioRxiv25 citations Open access
Semantic Scholar
Asterless is a Polo-like kinase 4 substrate that both activates and inhibits kinase activity depending on its phosphorylation state
Cody J. Boese, J. Nye, D. Buster, Tiffany A McLamarrah +4 more
2018Molecular Biology of the Cell25 citations Open access
Semantic Scholar
Structure of a Yeast Dyn2-Nup159 Complex and Molecular Basis for Dynein Light Chain-Nuclear Pore Interaction*
Erin M. Romes, A. Tripathy, K. Slep
2012Journal of Biological Chemistry25 citations Open access
Semantic Scholar
Mapping multivalency in the CLIP-170–EB1 microtubule plus-end complex
Yao-Dong Chen, Ping Wang, K. Slep
2018Journal of Biological Chemistry20 citations Open access
Semantic Scholar
Newly Characterized Region of CP190 Associates with Microtubules and Mediates Proper Spindle Morphology in Drosophila Stem Cells
K. M. Plevock, B. Galletta, K. Slep, N. Rusan
2015PLoS ONE20 citations Open access
Semantic Scholar
Structure of the ACF7 EF-Hand-GAR Module and Delineation of Microtubule Binding Determinants
T. Lane, E. Fuchs, K. Slep
2017Structure18 citations Open access
Semantic Scholar
αβ-Tubulin and microtubule-binding assays.
Jaime N Campbell, K. Slep
2011Methods in molecular biology18 citations
Semantic Scholar
It takes more than two to tango: Dishevelled polymerization and Wnt signaling
D. M. Roberts, K. Slep, M. Peifer
2007Nature Structural &Molecular Biology18 citations
Semantic Scholar
Structures of TOG1 and TOG2 from the human microtubule dynamics regulator CLASP1
J. Leano, K. Slep
2018bioRxiv17 citations Open access
Semantic Scholar
Biallelic mutations in the TOGARAM1 gene cause a novel primary ciliopathy
Valeria Morbidoni, E. Agolini, K. Slep, Luca Pannone +9 more
2020Journal of Medical Genetics14 citations
Semantic Scholar
Drosophila melanogaster Mini Spindles TOG3 Utilizes Unique Structural Elements to Promote Domain Stability and Maintain a TOG1- and TOG2-like Tubulin-binding Surface*
A. E. Howard, J. C. Fox, K. Slep
2015Journal of Biological Chemistry12 citations Open access
Semantic Scholar
Structure of the Human Discs Large 1 PDZ2– Adenomatous Polyposis Coli Cytoskeletal Polarity Complex: Insight into Peptide Engagement and PDZ Clustering
K. Slep
2012PLoS ONE10 citations Open access
Semantic Scholar
A Cytoskeletal Symphony: Owed to TOG.
K. Slep
2018Developmental Cell9 citations Open access
Semantic Scholar
Polo-like kinase 4 homodimerization and condensate formation regulate its own protein levels but are not required for centriole assembly
John M. Ryniawec, D. Buster, Lauren K. Slevin, Cody J. Boese +4 more
2023Molecular Biology of the Cell8 citations Open access
Semantic Scholar
Stu2 uses a 15-nm parallel coiled coil for kinetochore localization and concomitant regulation of the mitotic spindle
K. Haase, J. C. Fox, A. E. Byrnes, Rebecca C. Adikes +7 more
2017Molecular Biology of the Cell6 citations Open access
Semantic Scholar
The dual Ras-association domains of Drosophila Canoe have differential roles in linking cell junctions to the cytoskeleton during morphogenesis
E. D. McParland, Noah J Gurley, Leah R Wolfsberg, T. A. Butcher +5 more
2024bioRxiv5 citations Open access
Semantic Scholar
The Dilute domain in Canoe is not essential for linking cell junctions to the cytoskeleton but supports morphogenesis robustness
E. D. McParland, T. A. Butcher, Noah J Gurley, Ruth I. Johnson +2 more
2024Journal of Cell Science5 citations Open access
Semantic Scholar
Crystal structure of the Arabidopsis SPIRAL2 C-terminal domain reveals a p80-Katanin-like domain
Derek L. Bolhuis, R. Dixit, K. Slep
2022bioRxiv4 citations Open access
Semantic Scholar
A key role for Canoe’s intrinsically disordered region in linking cell junctions to the cytoskeleton
Corbin C. Jensen, Noah J Gurley, Avery J Mathias, Leah R Wolfsberg +4 more
2025bioRxiv3 citations Open access
Semantic Scholar
A divergent tumor overexpressed gene domain and oligomerization contribute to SPIRAL2 function in stabilizing microtubule minus ends
Yuanwei Fan, N. Bilkey, Derek L. Bolhuis, K. Slep +1 more
2023The Plant Cell3 citations Open access
Semantic Scholar
A key role for Canoe’s intrinsically disordered region in linking cell junctions to the cytoskeleton
Corbin C. Jensen, Noah J Gurley, Avery J Mathias, Leah R Wolfsberg +6 more
2025Journal of Cell Biology2 citations Open access
Semantic Scholar
A microtubule dynamics reconstitutional convention
K. Slep
2016Journal of Cell Biology2 citations Open access
Semantic Scholar
Clinical spectrum, molecular and functional analysis of variants in MACF1
Jordy Dekker, R. Schot, K. Aldinger, D. Everman +86 more
2025American Journal of Human Genetics1 citations Open access
Semantic Scholar
The Dilute domain of Canoe is not essential for Canoe’s role in linking adherens junctions to the cytoskeleton but contributes to robustness of morphogenesis
E. D. McParland, T. A. Butcher, Noah J Gurley, Ruth I. Johnson +2 more
2023bioRxiv1 citations Open access
Semantic Scholar
Polo-like kinase 4 homodimerization is not required for catalytic activation, autodestruction, or centriole assembly
John M. Ryniawec, D. Buster, Lauren K. Slevin, Cody J. Boese +4 more
2021bioRxiv1 citations Open access
Semantic Scholar
Cytoskeletal Repair: Microtubule Orthopaedics to the Rescue.
K. Slep
2020Current Biology1 citations Open access
Semantic Scholar
Cytoskeletal cryptography: structure and mechanism of an eraser
K. Slep
2019Nature Structural & Molecular Biology1 citations
Semantic Scholar

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M. Peifer×8
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D. Buster×7
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Gregory C. Rogers×7
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N. Rusan×6
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A. E. Byrnes×5

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Noah J Gurley×5

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Noah J Gurley — researcher profile on SciRah

Lauren K. Slevin×4

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Lauren K. Slevin — researcher profile on SciRah

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B. Galletta — researcher profile on SciRah

John M. Ryniawec×4

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John M. Ryniawec — researcher profile on SciRah

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Cody J. Boese — researcher profile on SciRah

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