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Yu-Man Tsui · SciRah

Researcher profile · Semantic Scholar

Yu-Man Tsui

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Yu-Man Tsui — researcher profile on SciRah

h-index: 17
Works: 49
Citations: 1,460

Most-cited papers

Single-cell RNA sequencing shows the immunosuppressive landscape and tumor heterogeneity of HBV-associated hepatocellular carcinoma
D. Ho, Yu-Man Tsui, L. Chan, K. Sze +13 more
2021Nature Communications273 citations Open access
Semantic Scholar
SENP1 promotes hypoxia-induced cancer stemness by HIF-1α deSUMOylation and SENP1/HIF-1α positive feedback loop
Chun-ping Cui, C. C. Wong, A. Kai, D. Ho +10 more
2017Gut198 citations Open access
Semantic Scholar
Single-cell transcriptomics reveals the landscape of intra-tumoral heterogeneity and stemness-related subpopulations in liver cancer.
D. Ho, Yu-Man Tsui, K. Sze, L. Chan +6 more
2019Cancer Letters141 citations Open access
Semantic Scholar
Cellular heterogeneity and plasticity in liver cancer.
L. Chan, Yu-Man Tsui, D. Ho, I. Ng
2021Seminars in Cancer Biology125 citations Open access
Semantic Scholar
Cancer stemness in hepatocellular carcinoma: mechanisms and translational potential
Yu-Man Tsui, L. Chan, I. Ng
2020British Journal of Cancer104 citations Open access
Semantic Scholar
Ephrin-A3/EphA2 axis regulates cellular metabolic plasticity to enhance cancer stemness in hypoxic hepatocellular carcinoma.
Abdullah Husain, Yung T. Chiu, K. Sze, D. Ho +10 more
2022Journal of Hepatology81 citations Open access
Semantic Scholar
RALYL increases hepatocellular carcinoma stemness by sustaining the mRNA stability of TGF-β2
Xia Wang, Jin Wang, Yu-Man Tsui, C. Shi +13 more
2021Nature Communications74 citations Open access
Semantic Scholar
Hepatitis B Virus–Telomerase Reverse Transcriptase Promoter Integration Harnesses Host ELF4, Resulting in Telomerase Reverse Transcriptase Gene Transcription in Hepatocellular Carcinoma
K. Sze, D. Ho, Yung T. Chiu, Yu-Man Tsui +10 more
2020Hepatology68 citations Open access
Semantic Scholar
Reciprocal interactions between malignant cells and macrophages enhance cancer stemness and M2 polarization in HBV-associated hepatocellular carcinoma
Qing-Yang Zhang, Yu-Man Tsui, V. X. Zhang, Anna Lu +11 more
2024Theranostics55 citations Open access
Semantic Scholar
Antioxidant supplements promote tumor formation and growth and confer drug resistance in hepatocellular carcinoma by reducing intracellular ROS and induction of TMBIM1
V. X. Zhang, K. Sze, L. Chan, D. Ho +8 more
2021Cell & Bioscience49 citations Open access
Semantic Scholar
S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos
Xia Wang, Hongyang Huang, K. Sze, Jin Wang +12 more
2023Gut48 citations Open access
Semantic Scholar
Liquid Biopsy Using Cell-Free or Circulating Tumor DNA in the Management of Hepatocellular Carcinoma
Xueying Lyu, Yu-Man Tsui, D. Ho, I. Ng
2022Cellular and Molecular Gastroenterology and Hepatology32 citations Open access
Semantic Scholar
PFKFB4 Drives the Oncogenicity in TP53-Mutated Hepatocellular Carcinoma in a Phosphatase-Dependent Manner
Charles Shing Kam, Daniel Wai-Hung Ho, Vanessa Sheung-In Ming, Lu Tian +10 more
2023Cellular and Molecular Gastroenterology and Hepatology30 citations Open access
Semantic Scholar
APOBEC3B promotes hepatocarcinogenesis and metastasis through novel deaminase‐independent activity
Wei Ma, D. Ho, Karen Mf Sze, Yu-Man Tsui +3 more
2019Molecular Carcinogenesis26 citations
Semantic Scholar
Fueling HCC Dynamics: Interplay Between Tumor Microenvironment and Tumor Initiating Cells
Hongyang Huang, Yu-Man Tsui, Irene Oi-Lin Ng
2023Cellular and Molecular Gastroenterology and Hepatology20 citations Open access
Semantic Scholar
LANCL1, a cell surface protein, promotes liver tumor initiation through FAM49B-Rac1 axis to suppress oxidative stress
Hongyang Huang, Yu-Man Tsui, D. Ho, C. Chung +7 more
2023Hepatology19 citations Open access
Semantic Scholar
Multimodal Integrative Genomics and Pathology Analyses in Neoadjuvant Nivolumab Treatment for Intermediate and Locally Advanced Hepatocellular Carcinoma
T. Cheung, Daniel Wai-Hung Ho, S. Lyu, Qingyang Zhang +11 more
2023Liver Cancer18 citations Open access
Semantic Scholar
Multimodal sequencing of neoadjuvant nivolumab treatment in hepatocellular carcinoma reveals cellular and molecular immune landscape for drug response
Fan-Hong Zeng, Qing-Yang Zhang, Yu-Man Tsui, Huan-Huan Ma +10 more
2025Molecular Cancer16 citations Open access
Semantic Scholar
Single-Cell Transcriptomics of Liver Cancer: Hype or Insights?
Qing-yang Zhang, D. Ho, Yu-Man Tsui, I. Ng
2022Cellular and Molecular Gastroenterology and Hepatology14 citations Open access
Semantic Scholar
Interplay among extracellular vesicles, cancer stemness and immune regulation in driving hepatocellular carcinoma progression.
Yu-Man Tsui, Lu Tian, Jing-Yi Lu, Huan-Huan Ma +1 more
2024Cancer Letters13 citations Open access
Semantic Scholar
Dishevelled-3 phosphorylation is governed by HIPK2/PP1Cα/ITCH axis and the non-phosphorylated form promotes cancer stemness via LGR5 in hepatocellular carcinoma
Yu-Man Tsui, K. Sze, E. Tung, D. Ho +2 more
2017OncoTarget9 citations Open access
Semantic Scholar
Sorted-Cell Sequencing on HCC Specimens Reveals EPS8L3 as a Key Player in CD24/CD13/EpCAM-Triple Positive, Stemness-Related HCC Cells
Yu-Man Tsui, D. Ho, K. Sze, J. Lee +10 more
2024Cellular and Molecular Gastroenterology and Hepatology8 citations Open access
Semantic Scholar
Targeting sterol O-acyltransferase 1 rewires fatty acid metabolism and uncovers immune vulnerability in hepatocellular carcinoma
Huan-Huan Ma, V. X. Zhang, Yu-Man Tsui, J. Lee +9 more
2025Hepatology7 citations Open access
Semantic Scholar
Spatiotemporal dynamics of T cells in peripheral blood and tumor underlying differential responses to neoadjuvant PD-1 blockade in hepatocellular carcinoma
Ya-Jing Zhang, Yu-Man Tsui, J. Lee, Tan-To Cheung +2 more
2025Journal for ImmunoTherapy of Cancer7 citations
Semantic Scholar
GPD1L supports glycerol-3-phosphate and triacylglycerol synthesis and promotes tumor progression in HCC
T. Yu, Luqing Zhao, K. Sze, Lu Tian +8 more
2025Hepatology5 citations Open access
Semantic Scholar
Repurposing Resmetirom suppresses MASH-associated hepatocellular carcinoma, with mechanistic implications of MDK/LRP1-mediated metabolic reprogramming and immunosuppression
V. X. Zhang, Tina Suoangbaji, Yu-Man Tsui, K. Sze +9 more
2026Hepatology4 citations Open access
Semantic Scholar
Cancer stem cells in hepatocellular carcinoma: platforms, updates, challenges and future perspectives
Jing Lu, D. O, Yu-Man Tsui, Irene Oi-Lin Ng
2025Cancer Biology and Medicine4 citations Open access
Semantic Scholar
Cancer stemness in hepatocellular carcinoma: mechanisms and translational potential
Yu-Man Tsui, L. Chan, I. Ng
2020British Journal of Cancer4 citations Open access
Semantic Scholar
Lipid Metabolism and Immune Response in Hepatocellular Carcinoma: Interplay Driving Tumor Progression
T. Yu, Yu-Man Tsui, V. X. Zhang, Huan-Huan Ma +1 more
2025Cancer Heterogeneity and Plasticity3 citations Open access
Semantic Scholar
Tumor microenvironment and metabolic reprogramming in MASLD-related hepatocellular carcinoma.
V. X. Zhang, T. Yu, Yu-Man Tsui, Irene Oi-Lin Ng
2026Trends in Molecular Medicine2 citations
Semantic Scholar
MASLD/MASH—New mechanisms and treatments
V. X. Zhang, Yu-Man Tsui, Irene Oi-Lin Ng
2025Hepatology Communications2 citations
Semantic Scholar
Nuclear localization of BRCA1-associated protein 1 is important in suppressing hepatocellular carcinoma metastasis via CTCF and NRF1/OGT axis
Xiaoyu Xie, Yu-Man Tsui, V. X. Zhang, T. Yu +9 more
2025Cell Death and Disease2 citations Open access
Semantic Scholar
Resolution of Optimal Mitochondrial and Nuclear DNA Enrichment in Target-Panel Sequencing and Physiological Mitochondrial DNA Copy Number Estimation in Liver Cancer and Non-Liver Cancer Subjects
Xueying Lyu, Yu-Man Tsui, Ivan Tam, Po-Man Li +4 more
2024Cancers2 citations Open access
Semantic Scholar
Unraveling the tumor-initiating cells in hepatocellular carcinoma.
Yu-Man Tsui, D. Ho, I. O. Ng
2024Cancer Cell2 citations Open access
Semantic Scholar
Multimodal sequencing identifies synergistic mechanisms driving resistance to neoadjuvant nivolumab treatment in hepatocellular carcinoma
Fan-Hong Zeng, Jia-Xin Guo, Zheng Zeng, V. X. Zhang +8 more
2026Molecular Cancer1 citations Open access
Semantic Scholar
Transcription factor AP-4 reactivates telomerase reverse transcriptase independently of genome alteration in non-HBV associated hepatocellular carcinoma
Huiju Lim, Trevor Wu, Eliana Mary Senires Suarez, T. Yu +5 more
2024Cancer Heterogeneity and Plasticity1 citations Open access
Semantic Scholar
Multimodal integrative genomics and pathology analyses in neoadjuvant nivolumab treatment for borderline resectable HCC
T. Cheung, D. Ho, S. Lyu, Qing-Yang Zhang +11 more
2023Journal of Hepatology1 citations
Semantic Scholar
Abstract 4014: APOBEC3B promotes hepatocarcinogenesis and metastasis through novel deaminase-independent activity
I. Ng, Wei Ma, D. Ho, Karen Mf Sze +3 more
2018Tumor Biology1 citations
Semantic Scholar
Abstract 2431: EFNA3, a key functional mediator of hypoxic microenvironment in hepatocellular carcinoma
Abdullah Husain, Yung T. Chiu, D. Ho, K. Sze +4 more
2018Molecular and Cellular Biology / Genetics1 citations
Semantic Scholar
Abstract 1643: Targeting LANCL1 with a humanized monoclonal antibody suppresses tumorigenesis in hepatocellular carcinoma
Chui-Yee Diana O, Yu-Man Tsui, Irene Oi-Lin Ng
2026Cancer Research0 citations
Semantic Scholar
Correction: Multimodal sequencing identifies synergistic mechanisms driving resistance to neoadjuvant nivolumab treatment in hepatocellular carcinoma
Fan-Hong Zeng, Jia-Xin Guo, Zheng Zeng, V. X. Zhang +8 more
2026Molecular Cancer0 citations Open access
Semantic Scholar
Abstract 6484: Single-cell transcriptomic analysis of hepatocellular carcinoma: elucidating intratumoral heterogeneity and immune microenvironment crosstalk
Qing-Yang Zhang, Yu-Man Tsui, V. X. Zhang, Daniel Wai-Hung Ho +1 more
2025Cancer Research0 citations
Semantic Scholar
Abstract 425: GPD1L participates in glycerol-3-phosphate biogenesis and promotes tumor initiation and invasion in hepatocellular carcinoma
T. Yu, Luqing Zhao, Lu Tian, Charles Shing Kam +6 more
2024Cancer Research0 citations
Semantic Scholar
Abstract 6982: The roles of NDRG1 in HCC progression and its clinical significance
Jing-Yi Lu, Lu Tian, Yu-Man Tsui, Xia Wong +3 more
2024Cancer Research0 citations
Semantic Scholar
Abstract 468: Antioxidant supplements may accelerate the formation and progression of hepatocellular carcinoma in vitro and in vivo
Xin Zhang, Eva K. Lee, Yu-Man Tsui, M. Sze +10 more
2018Molecular and Cellular Biology / Genetics0 citations
Semantic Scholar
Single-Cell Transcriptome Sequencing Reveals Intra-Tumor Heterogeneity and Rare Stemness-Related Cell Subpopulation in Hepatocellular Carcinoma
Dwh Ho, Yu-Man Tsui, Mf Sze, LK Chan +8 more
20180 citations
Semantic Scholar
Overexpression of leucine-rich repeat-containing G-protein coupled receptor 5 (LGR5) in a subset of hepatocellular carcinoma (HCC) promotes cancer stemness properties and cell migration of HCC cells
Yu-Man Tsui, K.-M. Sze, E. Tung, T. Lee +1 more
20160 citations
Semantic Scholar
Study of the roles of dishevelled-3 in stemness and cell migration in hepatocellular carcinoma
Yu-Man Tsui
20130 citations Open access
Semantic Scholar
Abstract 1074: Dishevelled 3 (Dvl3) is upregulated and enhances cell migration and invasion in hepatocellular carcinoma
Yu-Man Tsui, E. Tung, C. Mak, I. Ng
20110 citations
Semantic Scholar

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