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Eduardo J. Mascareno · SciRah

Researcher profile · Semantic Scholar

Eduardo J. Mascareno

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Eduardo J. Mascareno — researcher profile on SciRah

h-index: 17
Works: 49
Citations: 973

Most-cited papers

JAK/STAT Signaling Is Associated With Cardiac Dysfunction During Ischemia and Reperfusion
Eduardo J. Mascareno, Mohammed El-Shafei, N. Maulik, M. Sato +3 more
2001Circulation199 citations Open access
Semantic Scholar
Signal transduction and activator of transcription (STAT) protein-dependent activation of angiotensinogen promoter: a cellular signal for hypertrophy in cardiac muscle.
Eduardo J. Mascareno, M. Dhar, M. Siddiqui
1998Proceedings of the National Academy of Sciences of the United States of America128 citations Open access
Semantic Scholar
Vitamin C inhibits hypoxia-induced damage and apoptotic signaling pathways in cardiomyocytes and ischemic hearts.
V. Guaiquil, D. Golde, D. Beckles, Eduardo J. Mascareno +1 more
2004Free Radical Biology & Medicine83 citations
Semantic Scholar
The functional role of the JAK-STAT pathway in post-infarction remodeling.
H. El-Adawi, Li-li Deng, Anthony Tramontano, Steven Smith +4 more
2003Cardiovascular Research82 citations
Semantic Scholar
The role of Jak/STAT signaling in heart tissue renin-angiotensin system
Eduardo J. Mascareno, M. Siddiqui
2000Molecular and Cellular Biochemistry60 citations
Semantic Scholar
Inhibition of Jak2 phosphorylation attenuates pressure overload cardiac hypertrophy.
D. Beckles, Eduardo J. Mascareno, M. Siddiqui
2006Vascular pharmacology50 citations
Semantic Scholar
Tissue-specific transcription of the cardiac myosin light-chain 2 gene is regulated by an upstream repressor element
R.-A. Shen, Shyamal K. Goswami, Eduardo J. Mascareno, Ashok Kumar +1 more
1991Molecular and Cellular Biology38 citations Open access
Semantic Scholar
Pivotal role of cardiac lineage protein-1 (CLP-1) in transcriptional elongation factor P-TEFb complex formation in cardiac hypertrophy.
Jorge Espinoza-Derout, M. Wagner, Katayoun Shahmiri, Eduardo J. Mascareno +2 more
2007Cardiovascular Research34 citations Open access
Semantic Scholar
Positive Transcription Elongation Factor b (P-TEFb) Activity in Compensatory Myocardial Hypertrophy is Regulated by Cardiac Lineage Protein-1
Jorge Espinoza-Derout, M. Wagner, L. Salciccioli, J. Lazar +4 more
2009Circulation Research31 citations Open access
Semantic Scholar
Janus kinase-2 signaling mediates apoptosis in rat cardiomyocytes.
Eduardo J. Mascareno, D. Beckles, M. Siddiqui
2005Vascular pharmacology29 citations Open access
Semantic Scholar
Cross-talk between calcineurin/NFAT and Jak/STAT signalling induces cardioprotective αB-crystallin gene expression in response to hypertrophic stimuli
Irena Manukyan, J. Galatioto, Eduardo J. Mascareno, S. Bhaduri +1 more
2009Journal of Cellular and Molecular Medicine28 citations Open access
Semantic Scholar
A Ternary Complex of Transcription Factors, Nishéd and NFATc4, and Co-activator p300 Bound to an Intronic Sequence, Intronic Regulatory Element, Is Pivotal for the Up-regulation of Myosin Light Chain-2v Gene in Cardiac Hypertrophy*
Sumy Mathew, Eduardo J. Mascareno, M. Siddiqui
2004Journal of Biological Chemistry28 citations Open access
Semantic Scholar
Enhanced Hypertrophy In ob/ob Mice Due To An Impairment in Expression Of Atrial Natriuretic Peptide
Eduardo J. Mascareno, D. Beckles, Manya Dhar-Mascareño, M. Siddiqui
2009Vascular pharmacology26 citations Open access
Semantic Scholar
Cardiac Lineage Protein-1 (CLP-1) Regulates Cardiac Remodeling via Transcriptional Modulation of Diverse Hypertrophic and Fibrotic Responses and Angiotensin II-transforming Growth Factor β (TGF-β1) Signaling Axis*
Eduardo J. Mascareno, J. Galatioto, I. Rozenberg, L. Salciccioli +5 more
2012Journal of Biological Chemistry24 citations Open access
Semantic Scholar
Cardiac Hypertrophy: Signal Transduction, Transcriptional Adaptation, and Altered Growth Control
M. Wagner, Eduardo J. Mascareno, M. Siddiqui
1999Annals of the New York Academy of Sciences23 citations
Semantic Scholar
Signal transduction and transcriptional adaptation in embryonic heart development and during myocardial hypertrophy
S. Ghatpande, S. Goswami, Eduardo J. Mascareno, M. Siddiqui
1999Molecular and Cellular Biochemistry22 citations
Semantic Scholar
CLP-1 associates with MyoD and HDAC to restore skeletal muscle cell regeneration
J. Galatioto, Eduardo J. Mascareno, M. Siddiqui
2010Journal of Cell Science17 citations Open access
Semantic Scholar
Distinct components of Janus kinase/signal transducer and activator of transcription signaling pathway mediate the regulation of systemic and tissue localized renin-angiotensin system.
Yue-Ling Guo, Eduardo J. Mascareno, M. Siddiqui
2004Molecular Endocrinology17 citations Open access
Semantic Scholar
Leptin-mediated differential regulation of microsomal triglyceride transfer protein in the intestine and liver affects plasma lipids
J. Iqbal, Eduardo J. Mascareno, S. Chua, M. Hussain
2020Journal of Biological Chemistry15 citations Open access
Semantic Scholar
Characterization of Trypanosoma cruzi infectivity, proliferation, and cytokine patterns in gut and pancreatic epithelial cells maintained in vitro
L. Martello, R. Wadgaonkar, Raavi Gupta, F. Machado +4 more
2013Parasitology Research10 citations
Semantic Scholar
Down‐regulation of cardiac lineage protein (CLP‐1) expression in CLP‐1 +/− mice affords cardioprotection against ischaemic stress
Eduardo J. Mascareno, Irena Manukyan, D. Das, M. Siddiqui
2009Journal of Cellular and Molecular Medicine9 citations Open access
Semantic Scholar
Hexim1, a Novel Regulator of Leptin Function, Modulates Obesity and Glucose Disposal.
Manya Dhar-Mascareño, Susana Ramírez, I. Rozenberg, Y. Rouillé +2 more
2016Molecular Endocrinology8 citations Open access
Semantic Scholar
Rapidly progressive course of Trypanosoma cruzi infection in mice heterozygous for hexamethylene bis-acetamide inducible 1 (Hexim1) gene.
Eduardo J. Mascareno, Raavi Gupta, L. Martello, Manya Dhar-Mascareño +6 more
2017Microbes and infection3 citations Open access
Semantic Scholar
Hexim1 heterozygosity stabilizes atherosclerotic plaque and decreased steatosis in ApoE null mice fed atherogenic diet.
Manya Dhar-Mascareño, I. Rozenberg, J. Iqbal, M. Hussain +2 more
2017International Journal of Biochemistry and Cell Biology3 citations Open access
Semantic Scholar
Downregulation of cardiac lineage protein‐1 confers cardioprotection through the upregulation of redox effectors
Narasimman Gurusamy, István Lekli, M. Ahsan, D. Ray +4 more
2010FEBS Letters3 citations Open access
Semantic Scholar
Clinical and immunogenomic outcomes of consolidative cytoreductive nephrectomy in patients with metastatic renal cell carcinoma treated with immune checkpoint blockade.
S. Reese, Hui Jiang, F. Kuo, Chih‐Ying Wu +12 more
2023Journal of Clinical Oncology1 citations
Semantic Scholar
Early Signaling by Vascular Endothelial Growth Factor and Placental Growth Factor in Human Bone Marrow-Derived Endothelial Cells Is Mediated by Superoxide
Manya Dhar-Mascareño, Eduardo J. Mascareno, D. Golde
2009Journal of Vascular Research1 citations Open access
Semantic Scholar
JAK/Stat Signaling in Cardiac Diseases
M. Siddiqui, Eduardo J. Mascareno
20031 citations
Semantic Scholar
Targeting Tyrosine Phosphorylation of HEXIM1 Attenuates Non-Small Cell Lung Carcinoma in Xenograft Model of Lung Cancer
Mohammad Choudhary, Eduardo J. Mascareno, Manya Dhar-Mascareño, Renato Perez-Pena +1 more
2019Journal of the American College of Surgeons0 citations
Semantic Scholar
Role of Hexim1 in Chagas Disease-Associated Cardiomyopathy
Mohammad Choudhary, Eduardo J. Mascareno, Iman Simmonds, D. Beckles +2 more
2018Journal of the American College of Surgeons0 citations
Semantic Scholar
Characterization of Trypanosoma cruzi infectivity, proliferation, and cytokine patterns in gut and pancreatic epithelial cells maintained in vitro
L. Martello, R. Wadgaonkar, Raavi Gupta, F. Machado +4 more
2013Parasitology Research0 citations
Semantic Scholar
Abstract A61: Hexim-1 protein expression levels modulate TGFβ activity in prostate cancer
Manya Dhar-Mascareño, Eduardo J. Mascareno, Fang Liu
20120 citations
Semantic Scholar
CLP-1-Mediated Transcriptional Control of Hypertrophic Gene Programs Underlying Cardiac Hypertrophy
M. Siddiqui, M. Wagner, Jorge Espinoza-Derout, F. Huang +2 more
20110 citations
Semantic Scholar
Highlights of the 25th Conference of the European Society for Microcirculation
J. Padilla, Blair D. Johnson, S. Newcomer, Daniel P. Wilhite +47 more
2009Journal of Vascular Research0 citations Open access
Semantic Scholar
Repression of the cardiac myosin light chain‐2 gene in skeletal muscle requires site‐specific association of antithetic regulator, Nished, and HDACs
Sumy Mathew, J. Galatioto, Eduardo J. Mascareno, M. Siddiqui
2009Journal of Cellular and Molecular Medicine0 citations Open access
Semantic Scholar
9th International Symposium on Resistance Arteries (ISRA)
J. Padilla, Blair D. Johnson, S. Newcomer, Daniel P. Wilhite +47 more
2009Journal of Vascular Research0 citations Open access
Semantic Scholar
Contents Vol. 46, 2009
J. Padilla, Blair D. Johnson, S. Newcomer, Daniel P. Wilhite +47 more
2009Journal of Vascular Research0 citations Open access
Semantic Scholar
Subject Index Vol. 46, 2009
J. Padilla, Blair D. Johnson, S. Newcomer, Daniel P. Wilhite +47 more
2009Journal of Vascular Research0 citations Open access
Semantic Scholar
Abstract 3473: Down Regulation of Class I Histone Deacetylase in the Deficit of Cardiac Lineage Protein-1 Protects Heart from Ischemia Reperfusion Injury
Narasimman Gurusamy, István Lekli, Eduardo J. Mascareno, M. Siddiqui +1 more
20080 citations
Semantic Scholar
Cardiac Lineage Protein‐1 (CLP‐1) regulates the skeletal myogenic program through its association with MyoD and histone deacetylases (HDACs)
J. Galatioto, Eduardo J. Mascareno, M. Siddiqui
20080 citations
Semantic Scholar
P-375: Attenuation of cardiac hypertrophy in vivo by interference with the jak/Stat pathway
D. Beckles, Eduardo J. Mascareno, M. Siddiqui
20020 citations
Semantic Scholar
Methode permettant de reduire l'hypertension et l'insuffisance cardiaque
M. Siddiqui, Eduardo J. Mascareno
20020 citations
Semantic Scholar
Signal Transduction in Myofibrillogenesis, Cell Growth, and Hypertrophy
M. Siddiqui, M. Wagner, Eduardo J. Mascareno, S. Shafiq
20020 citations
Semantic Scholar
Inhibition of the JAK/STAT pathway with a specific JAK2 inhibitor (AG490) attenuates hypertrophy in an in vivo murine model
D. Beckles, Eduardo J. Mascareno, M. Siddiqui
20010 citations
Semantic Scholar
Nishéd: A novel regulator of skeletal myogenesis
Sumy Mathew, Eduardo J. Mascareno, M. Siddiqui
20000 citations
Semantic Scholar
Jak-stat pathway mediated activation of renin angiotensin system in myocardial hypertrophy and ischemia
Eduardo J. Mascareno, M. El-Shafie, Yue-Ling Guo, M. Siddiqui
20000 citations Open access
Semantic Scholar
Transcriptional adaptation and the role of stat proteins in myocardial hypertrophy
M. Siddiqui, Eduardo J. Mascareno
19980 citations Open access
Semantic Scholar
Transcriptional regulation of the cardiac myosin light chain 2 gene under normal and stress conditions
Eduardo J. Mascareno, M. Dhar, M. Siddiqui
19950 citations
Semantic Scholar
Tissue-Specific Transcription oftheCardiac MyosinLight-Chain 2 GeneIsRegulated byanUpstream Repressor Element
Eduardo J. Mascareno, Ashok Kumar
19910 citations
Semantic Scholar

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