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G. Birchenough · SciRah

Researcher profile · Semantic Scholar

G. Birchenough

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G. Birchenough — researcher profile on SciRah

h-index: 23
Works: 49
Citations: 5,027

Most-cited papers

The mucus and mucins of the goblet cells and enterocytes provide the first defense line of the gastrointestinal tract and interact with the immune system
T. Pelaseyed, Joakim H. Bergström, J. K. Gustafsson, A. Ermund +9 more
2014Immunological Reviews1,242 citations Open access
Semantic Scholar
New developments in goblet cell mucus secretion and function
G. Birchenough, M. Johansson, J. Gustafsson, Joakim H. Bergström +1 more
2015Mucosal Immunology757 citations Open access
Semantic Scholar
Bifidobacteria or fiber protect against diet-induced microbiota-mediated colonic mucus deterioration
B. Schroeder, G. Birchenough, M. Ståhlman, L. Arike +3 more
2017Cell Host and Microbe615 citations Open access
Semantic Scholar
A sentinel goblet cell guards the colonic crypt by triggering Nlrp6-dependent Muc2 secretion
G. Birchenough, E. Nyström, M. Johansson, G. Hansson
2016Science516 citations Open access
Semantic Scholar
Structural weakening of the colonic mucus barrier is an early event in ulcerative colitis pathogenesis
Sjoerd van der Post, Karolina S. Jabbar, G. Birchenough, L. Arike +4 more
2019Gut488 citations Open access
Semantic Scholar
An intercrypt subpopulation of goblet cells is essential for colonic mucus barrier function
E. Nyström, B. Martinez-Abad, L. Arike, G. Birchenough +6 more
2021Science311 citations Open access
Semantic Scholar
Gram-positive bacteria are held at a distance in the colon mucus by the lectin-like protein ZG16
Joakim H. Bergström, G. Birchenough, G. Katona, B. Schroeder +4 more
2016Proceedings of the National Academy of Sciences of the United States of America124 citations Open access
Semantic Scholar
The Nlrp6 inflammasome is not required for baseline colonic inner mucus layer formation or function
Joana K. Volk, E. Nyström, Sjoerd van der Post, B. Abad +7 more
2019Journal of Experimental Medicine110 citations Open access
Semantic Scholar
Calcium-activated Chloride Channel Regulator 1 (CLCA1) Controls Mucus Expansion in Colon by Proteolytic Activity
E. Nyström, G. Birchenough, Sjoerd van der Post, L. Arike +3 more
2018EBioMedicine90 citations Open access
Semantic Scholar
Dietary destabilisation of the balance between the microbiota and the colonic mucus barrier
G. Birchenough, B. Schroeder, F. Bäckhed, G. Hansson
2018Gut microbes79 citations Open access
Semantic Scholar
Hypervirulent Clostridium difficile PCR-Ribotypes Exhibit Resistance to Widely Used Disinfectants
Lisa F. Dawson, E. Valiente, Elizabeth H. Donahue, G. Birchenough +1 more
2011PLoS ONE74 citations Open access
Semantic Scholar
Gram-positive bacteria are held at a distance in the colon mucus by the lectin-like protein ZG16.
Joakim H. Bergström, G. Birchenough, G. Katona, B. Schroeder +4 more
2017Proceedings of the National Academy of Sciences of the United States of America60 citations Open access
Semantic Scholar
NOX1-dependent redox signaling potentiates colonic stem cell proliferation to adapt to the intestinal microbiota by linking EGFR and TLR activation
Sjoerd van der Post, G. Birchenough, Jason M. Held
2021Cell Reports55 citations Open access
Semantic Scholar
Altered Innate Defenses in the Neonatal Gastrointestinal Tract in Response to Colonization by Neuropathogenic Escherichia coli
G. Birchenough, M. Johansson, R. Stabler, F. Dalgakiran +4 more
2013Infection and Immunity46 citations Open access
Semantic Scholar
Muc2-dependent microbial colonization of the jejunal mucus layer is diet sensitive and confers local resistance to enteric pathogen infection
G. Birchenough, B. Schroeder, S. Sharba, L. Arike +8 more
2023Cell Reports45 citations Open access
Semantic Scholar
Transglutaminase 3 crosslinks the secreted gel-forming mucus component Mucin-2 and stabilizes the colonic mucus layer
Jack D A Sharpen, B. Dolan, E. Nyström, G. Birchenough +5 more
2022Nature Communications42 citations Open access
Semantic Scholar
Obesity-associated microbiota contributes to mucus layer defects in genetically obese mice
B. Schroeder, G. Birchenough, Meenakshi Pradhan, E. Nyström +3 more
2020Journal of Biological Chemistry40 citations Open access
Semantic Scholar
Postnatal development of the small intestinal mucosa drives age-dependent, regio-selective susceptibility to Escherichia coli K1 infection
G. Birchenough, F. Dalgakiran, Luci A. Witcomb, M. Johansson +3 more
2017Scientific Reports32 citations Open access
Semantic Scholar
Rainbow trout gastrointestinal mucus, mucin production, mucin glycosylation and response to lipopolysaccharide.
S. Sharba, H. Sundh, K. Sundell, John Benktander +3 more
2022Fish and Shellfish Immunology31 citations
Semantic Scholar
Forming a mucus barrier along the colon
G. Birchenough, M. Johansson
2020Science29 citations
Semantic Scholar
Administration of capsule-selective endosialidase E minimizes upregulation of organ gene expression induced by experimental systemic infection with Escherichia coli K1
A. Zelmer, Melissa J. Martin, O. Gundogdu, G. Birchenough +4 more
2010Microbiology28 citations Open access
Semantic Scholar
The Goblet Cell Protein Clca1 (Alias mClca3 or Gob-5) Is Not Required for Intestinal Mucus Synthesis, Structure and Barrier Function in Naive or DSS-Challenged Mice
N. A. Erickson, E. Nyström, L. Mundhenk, L. Arike +7 more
2015PLoS ONE27 citations Open access
Semantic Scholar
Gill Mucus and Gill Mucin O-glycosylation in Healthy and Amebic Gill Disease-Affected Atlantic Salmon
John Benktander, J. Padra, B. Maynard, G. Birchenough +7 more
2020Microorganisms26 citations Open access
Semantic Scholar
Low-grade intestinal inflammation two decades after pelvic radiotherapy
Sravani Devarakonda, A. Thorsell, P. Hedenström, Azar Rezapour +22 more
2023EBioMedicine23 citations Open access
Semantic Scholar
Functional mucous layer and healing of proximal colonic anastomoses in an experimental model
J. W. A. M. Bosmans, A. Jongen, G. Birchenough, E. Nyström +4 more
2017British Journal of Surgery22 citations Open access
Semantic Scholar
Non-Invasive Model of Neuropathogenic Escherichia coli Infection in the Neonatal Rat
F. Dalgakiran, Luci A. Witcomb, A. J. McCarthy, G. Birchenough +1 more
2014Journal of Visualized Experiments22 citations Open access
Semantic Scholar
Enteric nervous system-derived VIP restrains differentiation of LGR5+ stem cells toward the secretory lineage impeding type 2 immune programs
M. Jakob, Nele Sterczyk, Sotiria Boulekou, Patrycja M. Forster +35 more
2025Nature Immunology20 citations
Semantic Scholar
Mechanisms of uropathogenic E. coli mucosal association in the gastrointestinal tract
Philippe N Azimzadeh, G. Birchenough, Nathaniel C. Gualbuerto, J. Pinkner +13 more
2025Science Advances16 citations Open access
Semantic Scholar
Trans-Golgi protein TVP23B regulates host-microbe interactions via Paneth cell homeostasis and Goblet cell glycosylation
Ran Song, William McAlpine, Aaron M Fond, Evan Nair-Gill +14 more
2023Nature Communications14 citations Open access
Semantic Scholar
Bacteria Tell Us How to Protect Our Intestine.
G. Birchenough, G. Hansson
2017Cell Host and Microbe14 citations Open access
Semantic Scholar
Microbial experience through housing in a farmyard-type environment alters intestinal barrier properties in mouse colons
H. Arnesen, T. Markussen, G. Birchenough, Signe Birkeland +4 more
2023Scientific Reports11 citations Open access
Semantic Scholar
Cross-kingdom-mediated detection of intestinal protozoa through NLRP6.
N. Winsor, G. Bayer, O. Singh, Jeremy K. Chan +17 more
2025Cell Host and Microbe7 citations Open access
Semantic Scholar
Antenatal Ureaplasma infection induces ovine small intestinal goblet cell defects: a strong link with NEC pathology
Charlotte van Gorp, I. H. de Lange, M. Hütten, C. López-Iglesias +9 more
2022Tissue Barriers6 citations Open access
Semantic Scholar
Loss of Trefoil Factor 2 Sensitizes Rat Pups to Systemic Infection with the Neonatal Pathogen Escherichia coli K1
A. J. McCarthy, G. Birchenough, P. W. Taylor
2019Infection and Immunity6 citations Open access
Semantic Scholar
Neonatal microbiota colonization primes maturation of goblet cell–mediated protection in the pre-weaning colon
Åsa Johansson, Mahadevan Venkita Subramani, Bahtiyar Yilmaz, E. Nyström +10 more
2025Journal of Experimental Medicine4 citations Open access
Semantic Scholar
The Yeh pilus adhesin is equipped with an α-helical flap motif, which contributes to pectin adherence
Kevin O. Tamadonfar, Roger D. Klein, Edward D. B. Lopatto, Maxwell I Zimmerman +12 more
2026Science Advances2 citations Open access
Semantic Scholar
A. salmonicida infection inhibits rainbow trout gill mucin production.
S. Sharba, H. Sundh, Licínia Santos, Kristina Sundell +5 more
2025Fish and Shellfish Immunology1 citations Open access
Semantic Scholar
Antenatal Ureaplasma Infection Causes Colonic Mucus Barrier Defects: Implications for Intestinal Pathologies
Charlotte van Gorp, I. H. de Lange, M. Hütten, Carmen Lopez-Iglesias +11 more
2024International Journal of Molecular Sciences1 citations Open access
Semantic Scholar
Neonatal microbiota colonization drives maturation of primary and secondary goblet cell mediated protection in the pre-weaning colon
Åsa Johansson, M. V. Subramani, B. Yilmaz, E. Nyström +10 more
2024bioRxiv1 citations
Semantic Scholar
Muc2-Dependent Microbial Colonization of the Jejunal Mucus Layer is Diet Sensitive and Confers Resistance to Enteric Pathogen Infection
G. Birchenough, B. Schroeder, S. Sharba, L. Arike +5 more
2021Social Science Research Network1 citations
Semantic Scholar
Cross-Linking of the MUC2 Mucin by Isopeptide Bonds Stabilizes the Colon Mucus and is Altered in Patients with Ulcerative Colitis
C. Recktenwald, L. Arike, G. Birchenough, Andrew Schuette +2 more
20171 citations
Semantic Scholar
The Impact of Diet and Obesity on Intestinal Mucus Barrier Function
G. Birchenough, Björn O. Schröder, F. Bäckhed, G. Hansson
20171 citations
Semantic Scholar
Ex vivo imaging and enzymatic analysis of intestinal mucus.
E. Nyström, B. Dolan, G. Birchenough, Malin E. V. Johansson
2026Methods in Enzymology0 citations
Semantic Scholar
PyCycleBio: modelling non-sinusoidal-oscillator systems in temporal biology
Alexander R. Bennett, G. Birchenough, Daniel Bojar
2025bioRxiv0 citations Open access
Semantic Scholar
Correction: Neonatal microbiota colonization primes maturation of goblet cell–mediated protection in the pre-weaning colon
Åsa Johansson, M. V. Subramani, B. Yilmaz, E. Nyström +10 more
2025Journal of Experimental Medicine0 citations
Semantic Scholar
Transglutaminase 3 crosslinks secreted MUC2 and stabilizes the colonic mucus layer
Jack D A Sharpen, B. Dolan, E. Nyström, G. Birchenough +5 more
20210 citations Open access
Semantic Scholar
The Colonic Surface Goblet Cells Secrete Mucus Important for Proper Protective Mucus Layer Formation
E. Nyström, B. Martinez-Abad, L. Arike, G. Birchenough +1 more
20170 citations
Semantic Scholar
Analysis of intestinal factors contributing to the age-dependency of systemic neuropathogenic Escherichia coli K1 infection in the neonatal rat
G. Birchenough
20130 citations
Semantic Scholar
The Distribution of Assistant Curates
A. Deacon, G. Birchenough
19490 citations
Semantic Scholar

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G. Hansson×21
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G. Hansson — researcher profile on SciRah
E. Nyström×18
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E. Nyström — researcher profile on SciRah
M. Johansson×17
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M. Johansson — researcher profile on SciRah
L. Arike×15
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B. Schroeder — researcher profile on SciRah

Sjoerd van der Post×5

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Malin E. V. Johansson×5

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F. Bäckhed — researcher profile on SciRah

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P. W. Taylor — researcher profile on SciRah

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S. Sharba — researcher profile on SciRah

C. Recktenwald×5

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T. Pelaseyed×4

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T. Pelaseyed — researcher profile on SciRah