Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

Alessandra Castegna · SciRah

Researcher profile · Semantic Scholar

Alessandra Castegna

Share profile

Alessandra Castegna — researcher profile on SciRah

h-index: 41
Works: 86
Citations: 11K

Most-cited papers

The Metabolic Signature of Macrophage Responses
A. Viola, F. Munari, R. Sánchez-Rodríguez, Tommaso Scolaro +1 more
2019Frontiers in Immunology1,819 citations Open access
Semantic Scholar
Evidence of oxidative damage in Alzheimer's disease brain: central role for amyloid beta-peptide.
D. Butterfield, Jennifer Drake, C. Pocernich, Alessandra Castegna
2001Trends in Molecular Medicine1,177 citations
Semantic Scholar
Evidence that amyloid beta-peptide-induced lipid peroxidation and its sequelae in Alzheimer's disease brain contribute to neuronal death.
D. Butterfield, Alessandra Castegna, C. Lauderback, Jennifer Drake
2002Neurobiology of Aging737 citations
Semantic Scholar
Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part II: dihydropyrimidinase‐related protein 2, α‐enolase and heat shock cognate 71
Alessandra Castegna, M. Aksenov, V. Thongboonkerd, J. Klein +4 more
2002Journal of Neurochemistry627 citations
Semantic Scholar
Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part I: creatine kinase BB, glutamine synthase, and ubiquitin carboxy-terminal hydrolase L-1.
Alessandra Castegna, M. Aksenov, M. Aksenova, V. Thongboonkerd +5 more
2002Free Radical Biology & Medicine594 citations
Semantic Scholar
Proteomic identification of nitrated proteins in Alzheimer's disease brain
Alessandra Castegna, V. Thongboonkerd, J. Klein, B. Lynn +2 more
2003Journal of Neurochemistry560 citations
Semantic Scholar
Reactive Oxygen Species in Macrophages: Sources and Targets
M. Canton, R. Sánchez-Rodríguez, Iolanda Spera, Francisca C. Venegas +3 more
2021Frontiers in Immunology409 citations Open access
Semantic Scholar
Nutritional approaches to combat oxidative stress in Alzheimer's disease.
D. Butterfield, Alessandra Castegna, C. Pocernich, Jennifer Drake +2 more
2002Journal of Nutritional Biochemistry401 citations Open access
Semantic Scholar
UCP2 transports C4 metabolites out of mitochondria, regulating glucose and glutamine oxidation
A. Vozza, G. Parisi, F. De Leonardis, F. Lasorsa +11 more
2014Proceedings of the National Academy of Sciences of the United States of America400 citations Open access
Semantic Scholar
Pharmacologic or Genetic Targeting of Glutamine Synthetase Skews Macrophages toward an M1-like Phenotype and Inhibits Tumor Metastasis
Erika M. Palmieri, Alessio Menga, Rosa Martín-Pérez, Annamaria Quinto +9 more
2017Cell Reports377 citations Open access
Semantic Scholar
Mitochondrial DNA methylation as a next-generation biomarker and diagnostic tool.
V. Iacobazzi, Alessandra Castegna, V. Infantino, G. Andria
2013Molecular Genetics and Metabolism234 citations Open access
Semantic Scholar
Identification of the Mitochondrial NAD+ Transporter in Saccharomyces cerevisiae*
S. Todisco, G. Agrimi, Alessandra Castegna, F. Palmieri
2004Journal of Biological Chemistry216 citations Open access
Semantic Scholar
Proteomics in Alzheimer's disease: insights into potential mechanisms of neurodegeneration
D. Butterfield, Debra Boyd-Kimball, Alessandra Castegna
2003Journal of Neurochemistry188 citations Open access
Semantic Scholar
Identification of mitochondrial carriers in Saccharomyces cerevisiae by transport assay of reconstituted recombinant proteins.
F. Palmieri, G. Agrimi, E. Blanco, Alessandra Castegna +9 more
2006Biochimica et Biophysica Acta171 citations Open access
Semantic Scholar
Vitamin E and Neurodegenerative Disorders Associated with Oxidative Stress
D. Butterfield, Alessandra Castegna, Jennifer Drake, G. Scapagnini +1 more
2002Nutritional neuroscience170 citations
Semantic Scholar
Knockout of Slc25a19 causes mitochondrial thiamine pyrophosphate depletion, embryonic lethality, CNS malformations, and anemia
M. Lindhurst, G. Fiermonte, Shiwei Song, E. Struys +8 more
2006Proceedings of the National Academy of Sciences of the United States of America166 citations
Semantic Scholar
Quantitative proteomics analysis of specific protein expression and oxidative modification in aged senescence-accelerated-prone 8 mice brain.
H.-F. Poon, Alessandra Castegna, S. Farr, V. Thongboonkerd +5 more
2004Neuroscience152 citations
Semantic Scholar
Proteomic identification of proteins oxidized by Abeta(1-42) in synaptosomes: implications for Alzheimer's disease.
Debra Boyd-Kimball, Alessandra Castegna, R. Sultana, F. Poon +4 more
2005Brain Research140 citations
Semantic Scholar
Impairment of methyl cycle affects mitochondrial methyl availability and glutathione level in Down's syndrome.
V. Infantino, Alessandra Castegna, F. Iacobazzi, Iolanda Spera +3 more
2011Molecular Genetics and Metabolism137 citations Open access
Semantic Scholar
Identification and Functional Characterization of a Novel Mitochondrial Carrier for Citrate and Oxoglutarate in Saccharomyces cerevisiae*
Alessandra Castegna, Pasquale Scarcia, G. Agrimi, L. Palmieri +4 more
2010Journal of Biological Chemistry127 citations Open access
Semantic Scholar
Redox proteomics identification of oxidatively modified brain proteins in inherited Alzheimer's disease: An initial assessment
D. Butterfield, A. Gnjec, F. Poon, Alessandra Castegna +3 more
2006Journal of Alzheimer's Disease124 citations
Semantic Scholar
Metabolism and TAM functions—it takes two to tango
M. Mazzone, Alessio Menga, Alessandra Castegna
2018The FEBS Journal98 citations Open access
Semantic Scholar
Acetylation of human mitochondrial citrate carrier modulates mitochondrial citrate/malate exchange activity to sustain NADPH production during macrophage activation.
Erika M. Palmieri, Iolanda Spera, Alessio Menga, V. Infantino +6 more
2015Biochimica et Biophysica Acta96 citations Open access
Semantic Scholar
Proteomic analysis of brain proteins in the gracile axonal dystrophy (gad) mouse, a syndrome that emanates from dysfunctional ubiquitin carboxyl‐terminal hydrolase L‐1, reveals oxidation of key proteins
Alessandra Castegna, V. Thongboonkerd, J. Klein, Bert C. Lynn +4 more
2004Journal of Neurochemistry92 citations
Semantic Scholar
The mitochondrial side of epigenetics.
Alessandra Castegna, V. Iacobazzi, V. Infantino
2015Physiological Genomics89 citations Open access
Semantic Scholar
The Crowded Crosstalk between Cancer Cells and Stromal Microenvironment in Gynecological Malignancies: Biological Pathways and Therapeutic Implication
R. De Nola, Alessio Menga, Alessandra Castegna, Vera Loizzi +3 more
2019International Journal of Molecular Sciences83 citations Open access
Semantic Scholar
4-Hydroxynonenal oxidatively modifies histones: implications for Alzheimer's disease.
Jennifer Drake, Robin Petroze, Alessandra Castegna, Qun-Xing Ding +4 more
2004Neuroscience Letters76 citations
Semantic Scholar
Blockade of Glutamine Synthetase Enhances Inflammatory Response in Microglial Cells
Erika M. Palmieri, Alessio Menga, Aurore Lebrun, D. C. Hooper +3 more
2017Antioxidants and Redox Signaling75 citations Open access
Semantic Scholar
Hyperhomocysteinemia: related genetic diseases and congenital defects, abnormal DNA methylation and newborn screening issues.
V. Iacobazzi, V. Infantino, Alessandra Castegna, G. Andria
2014Molecular Genetics and Metabolism67 citations Open access
Semantic Scholar
Glufosinate constrains synchronous and metachronous metastasis by promoting anti‐tumor macrophages
Alessio Menga, M. Serra, S. Todisco, Carla Riera-Domingo +10 more
2020EMBO Molecular Medicine64 citations Open access
Semantic Scholar
Oxidative stress and reduced glutamine synthetase activity in the absence of inflammation in the cortex of mice with experimental allergic encephalomyelitis.
Alessandra Castegna, Luigi Palmieri, Iolanda Spera, Vito Porcelli +6 more
2011Neuroscience64 citations
Semantic Scholar
Glutamine Synthetase: Localization Dictates Outcome
Alessandra Castegna, Alessio Menga
2018Genes62 citations Open access
Semantic Scholar
Pharmacological targets of metabolism in disease: Opportunities from macrophages.
Alessandra Castegna, Rosanna Gissi, Alessio Menga, M. Montopoli +3 more
2020Pharmacology and Therapeutics61 citations
Semantic Scholar
SLC25A10 biallelic mutations in intractable epileptic encephalopathy with complex I deficiency
G. Punzi, Vito Porcelli, M. Ruggiu, M. F. Hossain +19 more
2018Human Molecular Genetics55 citations Open access
Semantic Scholar
Proteomics for the identification of specifically oxidized proteins in brain: Technology and application to the study of neurodegenerative disorders
D. Butterfield, Alessandra Castegna
2003Amino Acids54 citations
Semantic Scholar
SLC25A26 overexpression impairs cell function via mtDNA hypermethylation and rewiring of methyl metabolism
Alessio Menga, Erika M. Palmieri, A. Cianciulli, V. Infantino +5 more
2017The FEBS Journal51 citations Open access
Semantic Scholar
OPA1 drives macrophage metabolism and functional commitment via p65 signaling
R. Sánchez-Rodríguez, Caterina Tezze, Andrielly H R Agnellini, R. Angioni +14 more
2022Cell Death and Differentiation50 citations Open access
Semantic Scholar
Targeting monoamine oxidase to dampen NLRP3 inflammasome activation in inflammation
R. Sánchez-Rodríguez, F. Munari, R. Angioni, Francisca C. Venegas +6 more
2020Cellular & Molecular Immunology47 citations Open access
Semantic Scholar
The Effects of Chronic Lifelong Activation of the AHR Pathway by Industrial Chemical Pollutants on Female Human Reproduction
A. Cavallini, Catia Lippolis, M. Vacca, C. Nardelli +4 more
2016PLoS ONE46 citations Open access
Semantic Scholar
Molecular identification and functional characterization of a novel glutamate transporter in yeast and plant mitochondria.
Vito Porcelli, A. Vozza, Valeria M. Calcagnile, Ruggiero Gorgoglione +6 more
2018Biochimica et Biophysica Acta - Bioenergetics44 citations Open access
Semantic Scholar
Protein Carbonyl Levels—An Assessment of Protein Oxidation
Alessandra Castegna, Jennifer Drake, C. Pocernich, D. Butterfield
200343 citations
Semantic Scholar
Derivatives of Xanthic Acid are Novel Antioxidants: Application to Synaptosomes
C. Lauderback, Jennifer Drake, Dao-Hong Zhou, Janna M. Hackett +5 more
2003Free radical research41 citations
Semantic Scholar
Identification of mitochondrial thiamin diphosphate carriers from Arabidopsis and maize
Océane Frelin, G. Agrimi, V. Laera, Alessandra Castegna +5 more
2012Functional & Integrative Genomics39 citations
Semantic Scholar
Glutamine synthetase desensitizes differentiated adipocytes to proinflammatory stimuli by raising intracellular glutamine levels
Erika M. Palmieri, Iolanda Spera, Alessio Menga, V. Infantino +2 more
2014FEBS Letters36 citations Open access
Semantic Scholar
Down-regulation of the mitochondrial aspartate-glutamate carrier isoform 1 AGC1 inhibits proliferation and N-acetylaspartate synthesis in Neuro2A cells.
E. Profilo, Luis Emiliano Peña-Altamira, M. Corricelli, Alessandra Castegna +18 more
2017Biochimica et Biophysica Acta - Molecular Basis of Disease35 citations Open access
Semantic Scholar
Proteomic analysis of oxidatively modified proteins in Alzheimer's disease brain: insights into neurodegeneration.
D. Butterfield, Alessandra Castegna
2003Cellular and Molecular Biology34 citations
Semantic Scholar
Role of FOXA in mitochondrial citrate carrier gene expression and insulin secretion.
V. Iacobazzi, V. Infantino, F. Bisaccia, Alessandra Castegna +1 more
2009Biochemical and Biophysical Research Communications - BBRC33 citations
Semantic Scholar
The dominant-negative mitochondrial calcium uniporter subunit MCUb drives macrophage polarization during skeletal muscle regeneration
Simona Feno, F. Munari, D. V. Reane, Rosanna Gissi +6 more
2021Science Signaling29 citations Open access
Semantic Scholar
Identification of Mitochondrial Coenzyme A Transporters from Maize and Arabidopsis1[W][OA]
R. Zallot, G. Agrimi, Claudia Lerma-Ortiz, Howard J. Teresinski +8 more
2013Plant Physiology29 citations Open access
Semantic Scholar
Metabolic Features of Brain Function with Relevance to Clinical Features of Alzheimer and Parkinson Diseases
D. Butterfield, Maria Favia, Iolanda Spera, Annalisa Campanella +2 more
2022Molecules25 citations Open access
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

D. Butterfield×19
Invite
D. Butterfield — researcher profile on SciRah
F. Palmieri×13
Invite
F. Palmieri — researcher profile on SciRah
Alessio Menga×11
Invite
Alessio Menga — researcher profile on SciRah
V. Iacobazzi×9
Invite
V. Iacobazzi — researcher profile on SciRah

×8

Invite

V. Infantino — researcher profile on SciRah

Jennifer Drake×7

Invite

Jennifer Drake — researcher profile on SciRah

Iolanda Spera×7

Invite

Iolanda Spera — researcher profile on SciRah

Erika M. Palmieri×7

Invite

Erika M. Palmieri — researcher profile on SciRah

Invite

A. Viola — researcher profile on SciRah

Invite

L. Palmieri — researcher profile on SciRah

Invite

G. Agrimi — researcher profile on SciRah

V. Thongboonkerd×5

Invite

V. Thongboonkerd — researcher profile on SciRah