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M. Gorjánácz · SciRah

Researcher profile · Semantic Scholar

M. Gorjánácz

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M. Gorjánácz — researcher profile on SciRah

h-index: 21
Works: 43
Citations: 1,554

Most-cited papers

Caenorhabditis elegans BAF‐1 and its kinase VRK‐1 participate directly in post‐mitotic nuclear envelope assembly
M. Gorjánácz, Elke P. F. Klerkx, Vincent Galy, Rachel Santarella +3 more
2007EMBO Journal216 citations Open access
Semantic Scholar
Coordination of kinase and phosphatase activities by Lem4 enables nuclear envelope reassembly during mitosis.
C. Asencio, I. Davidson, Rachel Santarella-Mellwig, Thi Bach Nga Ly-Hartig +4 more
2012Cell182 citations Open access
Semantic Scholar
The Compartmentalized Bacteria of the Planctomycetes-Verrucomicrobia-Chlamydiae Superphylum Have Membrane Coat-Like Proteins
Rachel Santarella-Mellwig, Josef D. Franke, A. Jaedicke, M. Gorjánácz +4 more
2010PLoS Biology151 citations Open access
Semantic Scholar
Samp1 is a component of TAN lines and is required for nuclear movement
J. Borrego-Pinto, T. Jegou, D. Osório, F. Aurade +4 more
2012Journal of Cell Science109 citations Open access
Semantic Scholar
Mitotic lamin disassembly is triggered by lipid-mediated signaling
M. Mall, Thomas Walter, M. Gorjánácz, I. Davidson +3 more
2012Journal of Cell Biology84 citations Open access
Semantic Scholar
Lipin is required for efficient breakdown of the nuclear envelope in Caenorhabditis elegans
M. Gorjánácz, I. Mattaj
2009Journal of Cell Science84 citations
Semantic Scholar
Targeting the aryl hydrocarbon receptor (AhR) with BAY 2416964: a selective small molecule inhibitor for cancer immunotherapy
Christina Kober, Julian Roewe, N. Schmees, Lars Roese +27 more
2023Journal for ImmunoTherapy of Cancer83 citations Open access
Semantic Scholar
ATAD2 is an epigenetic reader of newly synthesized histone marks during DNA replication
S. Koo, A. Fernández-Montalván, V. Badock, C. Ott +6 more
2016OncoTarget78 citations Open access
Semantic Scholar
Isoform-selective ATAD2 chemical probe with novel chemical structure and unusual mode of action
A. Fernandez-Montalvan, M. Berger, Benno Kuropka, S. Koo +26 more
2017ACS Chemical Biology70 citations Open access
Semantic Scholar
The Caenorhabditis elegans SUN protein UNC-84 interacts with lamin to transfer forces from the cytoplasm to the nucleoskeleton during nuclear migration
C. Bone, Erin C. Tapley, M. Gorjánácz, Daniel A Starr
2014Molecular Biology of the Cell70 citations Open access
Semantic Scholar
Importin-α2 is critically required for the assembly of ring canals during Drosophila oogenesis
M. Gorjánácz, Géza Ádám, I. Török, B. Mechler +2 more
200251 citations Open access
Semantic Scholar
Novel Class of Potent and Cellularly Active Inhibitors Devalidates MTH1 as Broad-Spectrum Cancer Target.
Manuel Ellermann, A. Eheim, F. Rahm, J. Viklund +22 more
2017ACS Chemical Biology50 citations Open access
Semantic Scholar
Patterns of importin-α expression during Drosophila spermatogenesis
M. Giarrè, I. Török, R. Schmitt, M. Gorjánácz +2 more
200241 citations
Semantic Scholar
What can Caenorhabditis elegans tell us about the nuclear envelope?
M. Gorjánácz, A. Jaedicke, I. Mattaj
2007FEBS Letters32 citations Open access
Semantic Scholar
Creation of a Novel Class of Potent and Selective MutT Homologue 1 (MTH1) Inhibitors Using Fragment-Based Screening and Structure-Based Drug Design.
F. Rahm, J. Viklund, L. Trésaugues, Manuel Ellermann +18 more
2018Journal of Medicinal Chemistry29 citations Open access
Semantic Scholar
Selective depletion of tumor-infiltrating regulatory T cells with BAY 3375968, a novel Fc-optimized anti-CCR8 antibody
Helge G. Roider, S. Hoff, S. Tseng, Sandra Berndt +13 more
2024Clinical and Experimental Medicine (Testo stampato)26 citations Open access
Semantic Scholar
Nuclear assembly as a target for anti-cancer therapies
M. Gorjánácz
2014The Nucleus26 citations Open access
Semantic Scholar
Domains of Importin-α2 required for ring canal assembly during Drosophila oogenesis
M. Gorjánácz, I. Török, I. Pomozi, G. Garab +3 more
200623 citations
Semantic Scholar
Patterns of importin-alpha expression during Drosophila spermatogenesis.
M. Giarrè, I. Török, R. Schmitt, M. Gorjánácz +2 more
2002Journal of Structural Biology23 citations
Semantic Scholar
Importin-alpha 2 is critically required for the assembly of ring canals during Drosophila oogenesis.
M. Gorjánácz, Géza Ádám, I. Török, B. Mechler +2 more
2002Developmental Biology23 citations
Semantic Scholar
LEM-4 promotes rapid dephosphorylation of BAF during mitotic exit
M. Gorjánácz
2013The Nucleus21 citations Open access
Semantic Scholar
Sm protein down-regulation leads to defects in nuclear pore complex disassembly and distribution in C. elegans embryos
Daphna Joseph-Strauss, M. Gorjánácz, Rachel Santarella-Mellwig, Ekaterina Voronina +2 more
2012Developmental Biology19 citations Open access
Semantic Scholar
Pan-PI3K inhibition with copanlisib overcomes Treg- and M2-TAM-mediated immune suppression and promotes anti-tumor immune responses
Simon Heller, S. Glaeske, Katja Gluske, J. Paul +10 more
2023Clinical and Experimental Medicine (Testo stampato)17 citations Open access
Semantic Scholar
Coordination of Di-Acetylated Histone Ligands by the ATAD2 Bromodomain
Chiara M. Evans, M. Phillips, K. Malone, M. Tonelli +11 more
2021bioRxiv13 citations Open access
Semantic Scholar
Abstract 1288: Blocking tumor-associated immune suppression with BAY-218, a novel, selective aryl hydrocarbon receptor (AhR) inhibitor
I. Gutcher, Christina Kober, Lars Roese, Julian Roewe +14 more
2019Experimental and Molecular Therapeutics10 citations
Semantic Scholar
Discovery and Characterization of BAY-184: A New Potent and Selective Acylsulfonamide-Benzofuran In Vivo-Active KAT6AB Inhibitor
A. ter Laak, R. Hillig, Steven J. Ferrara, D. Korr +18 more
2024Journal of Medicinal Chemistry7 citations Open access
Semantic Scholar
Domains of Importin-alpha2 required for ring canal assembly during Drosophila oogenesis.
M. Gorjánácz, I. Török, I. Pomozi, G. Garab +3 more
2006Journal of Structural Biology7 citations
Semantic Scholar
Some Like It Hot: Switching Biology on the Microscope
M. Gorjánácz, I. Mattaj, J. Rietdorf
20073 citations
Semantic Scholar
Correction: The Compartmentalized Bacteria of the Planctomycetes-Verrucomicrobia-Chlamydiae Superphylum Have Membrane Coat-Like Proteins
Rachel Santarella-Mellwig, Josef D. Franke, A. Jaedicke, M. Gorjánácz +4 more
2018PLoS Biology2 citations Open access
Semantic Scholar
Specific Cooperation Between Imp-α2 and Imp-β/Ketel in Spindle Assembly During Drosophila Early Nuclear Divisions
Erika Viragh, M. Gorjánácz, I. Török, Tolga Eichhorn +4 more
2012G3: Genes, Genomes, Genetics2 citations Open access
Semantic Scholar
Abstract 2866: BAY 3375968: An afucosylated anti-CCR8 antibody depleting activated intratumoral regulatory T cells as a cancer immunotherapy
Helge G. Roider, S. Tseng, S. Hoff, S. Berndt +8 more
2022Cancer Research1 citations
Semantic Scholar
Abstract LB-123: Pulsatile inhibition of PI3K converts immune suppression by Tregs and M2-TAM to anti-tumor immune response in animal models insensitive or resistant to the monotherapies of PI3K and checkpoint inhibitors
S. Glaeske, Franziska Huebner, A. Anurin, A. Janzer +9 more
2018Immunology1 citations
Semantic Scholar
Abstract 5084: Potent and isoform-selective ATAD2 bromodomain inhibitor with unprecedented chemical structure and mode of action
A. Fernandez-Montalvan, M. Berger, Benno Kuropka, S. Koo +23 more
20171 citations
Semantic Scholar
Abstract 7064: Development of a new class of KAT6A/B inhibitors with in vivo efficacy.
A. ter Laak, R. Hillig, Steven J. Ferrara, D. Korr +19 more
2026Cancer Research0 citations
Semantic Scholar
Combining High-Dose Radiation with Dual CCR8 and PD-1 Blockade to Overcome Tumor Immune Suppression
Y. Hu, H. Barsoumian, A. Huang, T. Riad +6 more
2025International Journal of Radiation Oncology, Biology, Physics0 citations
Semantic Scholar
CCR8 positive Tregs and their correlation with immunotherapy response in advanced non-small cell lung cancer (NSCLC).
J. Guégan, Martin Szyska, Lucas Tombor, Reimo Tetzner +7 more
2025Journal of Clinical Oncology0 citations Open access
Semantic Scholar
729 Boosting anti-tumor immunity via triple combination of DGK, CCR8 and PD-L1 targeting agents
Dennis Kirchhoff, Helge G. Roider, Kirstin Petersen, W. M. Nadler +2 more
2024Regular and Young Investigator Award Abstracts0 citations Open access
Semantic Scholar
Abstract 689: Identification and optimization of novel chemical matter via a structure-based approach resulting in a probe for MTH1
M. Bauser, A. Giese, Manuel Ellermann, J. Guenther +22 more
2018Cancer Chemistry0 citations
Semantic Scholar
Abstract 5226: Novel class of potent and selective inhibitors efface MTH1 as broad-spectrum cancer target
Manuel Ellermann, A. Giese, A. Eheim, S. Bunse +12 more
20170 citations
Semantic Scholar
Abstract 5239: Probing the cancer epigenome: empowering target validation by open innovation
Ingo V. Hartung, C. Arrowsmith, V. Badock, Naomi Barak +25 more
20170 citations
Semantic Scholar
BAY-707 in complex with MTH1
Manuel Ellermann, A. Eheim, A. Giese, S. Bunse +19 more
20170 citations
Semantic Scholar
Abstract 4539: ATAD2 mediates DNA replication in cancer
S. Koo, A. Fernandez-Montalvan, Simon Holton, O. von Ahsen +5 more
20160 citations
Semantic Scholar
Prod is a novel DNA-binding protein that binds to the 1.686 g/cm 10 bp satellite repeat of
T. Török, M. Gorjánácz, P. Bryant, I. Kiss
20000 citations
Semantic Scholar

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