A. El Helali

Most-cited papers

1. Sequential transarterial chemoembolisation and stereotactic body radiotherapy followed by immunotherapy as conversion therapy for patients with locally advanced, unresectable hepatocellular carcinoma (START-FIT): a single-arm, phase 2 trial.

   Chi-Leung Chiang, K. Chiu, K. Chan, F. A. Lee +14 more

   2022The Lancet Gastroenterology and Hepatology111 citations

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2. ESMO Precision Oncology Working Group recommendations on the structure and quality indicators for molecular tumour boards in clinical practice.

   C. B. Westphalen, L. Bielo, P. Aftimos, H. Beltran +25 more

   2025Annals of Oncology58 citations Open access

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3. A Single-Arm Phase 2 Trial on Induction Chemotherapy Followed by Concurrent Chemoradiation in Nasopharyngeal Carcinoma Using a Reduced Cumulative Dose of Cisplatin

   Zhiyuan Xu, Li Yang, W. Ng, A. El Helali +10 more

   2022Frontiers in Oncology46 citations Open access

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4. Activation of MAPK signalling results in resistance to saracatinib (AZD0530) in ovarian cancer

   Niamh McGivern, A. El Helali, P. Mullan, I. McNeish +3 more

   2017OncoTarget27 citations Open access

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5. A meta-analysis with systematic review: Efficacy and safety of immune checkpoint inhibitors in patients with advanced gastric cancer

   A. El Helali, J. Tao, C. H. Wong, W. Chan +7 more

   2022Frontiers in Oncology22 citations Open access

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6. Oncolytic virus and tumor-associated macrophage interactions in cancer immunotherapy

   Marc Lecoultre, Paul R. Walker, A. El Helali

   2024Clinical and Experimental Medicine (Testo stampato)19 citations Open access

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7. Effectiveness and safety of continuous low-molecular-weight heparin versus switching to direct oral anticoagulants in cancer-associated venous thrombosis

   Wei Kang, Caige Huang, Vincent K. C. Yan, Yue Wei +13 more

   2024Nature Communications17 citations Open access

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8. Patterns of care and survival of Chinese glioblastoma patients in the temozolomide era: a Hong Kong population-level analysis over a 14-year period.

   P. Woo, S. Yau, T. Lam, Jenny K. S. Pu +21 more

   2022Neuro-Oncology Practice16 citations Open access

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9. The impact of the multi-disciplinary molecular tumour board and integrative next generation sequencing on clinical outcomes in advanced solid tumours

   A. El Helali, T. Lam, E. Ko, David J. H. Shih +15 more

   2023The Lancet Regional Health - Western Pacific15 citations Open access

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10. Perceptions about traditional Chinese medicine use among Chinese breast cancer survivors: A qualitative study

    Yik-Laam Hung, Siu-Sing Leung, Siu-Ting Pamela Chiu, Pik-Yi Li +7 more

    2022Cancer Medicine15 citations Open access

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11. Global trends indicate increasing consumption of dietary sodium and fiber in middle-income countries: A study of 30-year global macrotrends.

    Jun Tao, J. Quan, A. El Helali, Wendy W. T. Lam +1 more

    2023Nutrition Research13 citations

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12. Efficacy, safety, and correlative biomarkers of bintrafusp alfa in recurrent or metastatic nasopharyngeal cancer patients: a phase II clinical trial

    Chi-Leung Chiang, Tai-Chung Lam, James C. L. Li, K. S. Chan +16 more

    2023The Lancet Regional Health - Western Pacific13 citations Open access

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13. A first-in-human Phase I dose-escalation trial of the novel therapeutic peptide, ALM201, demonstrates a favourable safety profile in unselected patients with ovarian cancer and other advanced solid tumours

    A. El Helali, R. Plummer, G. Jayson, V. Coyle +9 more

    2022British Journal of Cancer12 citations Open access

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14. Cancer and fertility management: FIGO best practice advice

    Nikhil C. Purandare, F. Ruiloba, L. Nguyen-Hoang, S. Wilailak +23 more

    2025International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics11 citations Open access

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15. Integrated genomic and transcriptomic profiling of glioblastoma reveals ecDNA-driven heterogeneity and microenvironmental reprogramming.

    Wenshu Tang, Wing-Lun Lee, C. Lo, A. Chu +9 more

    2025Cell Reports10 citations Open access

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16. Adjuvant and post-surgical treatment in non-epithelial ovarian cancer.

    A. El Helali, G. Kwok, Ka-Yu Tse

    2021Best Practice & Research: Clinical Obstetrics & Gynaecology10 citations

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17. A comprehensive systematic review and network meta-analysis: the role of anti-angiogenic agents in advanced epithelial ovarian cancer

    A. El Helali, C. Wong, Horace C. W. Choi, W. Chan +6 more

    2021Scientific Reports8 citations Open access

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18. 383PA phase I dose-escalation study of the novel peptide ALM201 in patients (pts) with advanced solid tumours

    A. El Helali, R. Plummer, G. Jayson, V. Coyle +8 more

    20177 citations Open access

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19. Impact of alternating electric fields therapy for newly diagnosed WHO grade 4 astrocytoma on patient survival: a real-world propensity-score adjusted prospective multicenter study

    Peter Y. M. Woo, Jenny K. S. Pu, Lai-Fung Li, D. Wong +15 more

    2025Journal of Neuro-Oncology6 citations Open access

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20. Consensus Statements on Precision Oncology in the China Greater Bay Area

    T. Lam, W. C. Cho, J. Au, E. S. Ma +27 more

    2023JCO Precision Oncology5 citations Open access

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21. Anaplastic Lymphoma Kinase (ALK) Fusion as a Resistance Mechanism to Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitors With Complete Response After Osimertinib and Alectinib: A Case Report and Literature Review

    B. Cheung, A. El Helali, D. Leung

    2025Cureus4 citations Open access

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22. Development and validation of ACTTOP: a prediction model for severe anticancer treatment toxicities in older patients with solid malignancy.

    Wing-Lok Chan, H. Hou, Horace C. W. Choi, Siu-Long Thomas Yik +15 more

    2025Age and Ageing4 citations

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23. Direct oral anticoagulants versus low-molecular-weight heparin in patients with cancer-associated venous thrombosis: a cost-effectiveness analysis

    W. Kang, K. Peng, Vincent K. C. Yan, D. Al-Badriyeh +10 more

    2024Journal of Pharmaceutical Policy and Practice4 citations Open access

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24. Mapping glioblastoma’s isoform diversity using long-read single-cell analysis

    Wenshu Tang, C. Lo, A. Chu, Wing-Lun Lee +6 more

    2026Nature Communications3 citations Open access

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25. Role of Circulating Tumor DNA Tumor Fraction in Advanced Non–Small Cell Lung Cancer and Its Impact on Patient Treatment Outcomes: A Prospective Real-World Study

    B. Cheung, E. Ko, D. Shih, J. Wong +7 more

    2025JCO Precision Oncology3 citations Open access

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26. Fertility stimulation protocols in women with cancer

    Nikhil C. Purandare, G. Ryan, A. El Helali, D. Crosby

    2025International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics3 citations

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27. The diagnostic accuracy of next-generation sequencing in advanced NSCLC

    E. Ko, J. Wong, D. Shih, Isaac Ho +6 more

    2025The journal of liquid biopsy3 citations Open access

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28. Interpretable deep learning insights: Unveiling the role of 1 Gy volume on lymphopenia after radiotherapy in breast cancer.

    Fang Chen, P. Zhou, Ge Ren, E. K. Lee +10 more

    2024Radiotherapy and Oncology3 citations Open access

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29. Trends and age, sex, and race disparities in time to second primary cancer from 1990 to 2019

    Tiffany H Leung, A. El Helali, Xiaofei Wang, J. C. Ho +1 more

    2023Cancer Medicine3 citations Open access

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30. New reporting items and recommendations for randomized trials impacted by COVID-19 and force majeure events: a targeted approach

    Tiffany H Leung, J. Ho, A. El Helali, E. Vokes +2 more

    2022Annals of Translational Medicine3 citations Open access

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31. Bronchoesophageal fistula in a patient with stage IIIB non-small-cell lung cancer.

    G. Korpanty, S. Alken, L. Smyth, J. Greene +3 more

    2012Journal of Thoracic Oncology3 citations Open access

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32. High clinical actionability of a pan-cancer tissue-based combined DNA and RNA next generation sequencing assay in a diverse Asian population

    J. Lee, A. El Helali, D. J. J. Tan, Zi-Yi Wan +15 more

    2025npj Precision Oncology2 citations Open access

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33. The impact of timing of temozolomide chemoradiotherapy for newly diagnosed glioblastoma on patient overall survival: A multicenter retrospective study

    A. C. K. Lau, B. Chan, Carly S K Yeung, Lai-Fung Li +13 more

    2024Neuro-Oncology Advances2 citations

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34. Over one year of survival difference between distinct cohorts of glioblastoma patients

    Michael T. C. Poon, Peter Y. M. Woo, A. El Helali, Paul M. Brennan

    2023medRxiv2 citations Open access

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35. Antitumor activity of bintrafusp alfa in previously treated patients with recurrent or metastatic nasopharyngeal cancer (NPC): A single arm, prospective phase II trial.

    Chi-Leung Chiang, Tai-Chung Lam, Chun-Guang Li, W. Li +12 more

    2022Journal of Clinical Oncology2 citations

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36. Platinum based chemotherapy selects for PDGFRα dependent angiogenesis.

    N. Mccabe, A. El Helali, C. Steele, Lara Dura Perez +13 more

    20182 citations

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37. Tumor heterogeneity index from DCE-MRI for AKT-inhibition responder identification and reveals hot immune microenvironment for patients with breast cancer: a multi-omics analysis of I-SPY2 trial

    Xin-Zhi Teng, Jiang Zhang, Qingpei Lai, Wen Li +12 more

    2026Breast Cancer Research1 citations Open access

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38. Commentary on “Targeted release of a bispecific fusion protein SIRPα/Siglec-10 by oncolytic adenovirus reinvigorates tumor-associated macrophages to improve therapeutic outcomes in solid tumors”

    Marc Lecoultre, A. El Helali

    2025Journal for ImmunoTherapy of Cancer1 citations Open access

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39. Switching Cancer-associated Venous Thromboembolism Treatment from Continuous LMWH to DOACs: An Evaluation

    W. Kang, Chin-Yao Shen, M. Cheng, V. Yan +11 more

    2025Thrombosis and Haemostasis1 citations

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40. The TAC-GReD trial: The combination of talazoparib and carboplatin in DNA damage repair deficient recurrent high-grade glioma.

    M. Lecoultre, Peter Y. M. Woo, G. Leung, Shuk Wan Joyce Chow +6 more

    2024Journal of Clinical Oncology1 citations Open access

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41. Indoleamine 2,3-dioxygenase 1-mediated immune suppressive status is positively associated with brain metastasis in patients with non-small cell lung cancer

    Wei-Wei Chen, Li Yang, V. Lee, Liangliang Xu +23 more

    2024Journal of the National Cancer Center1 citations Open access

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42. An Evaluation of Gene-Diet Interaction Statistical Methods and Discovery of rs7175421-Whole Grain Interaction in Lung Cancer

    Jun Tao, A. El Helali, J. Ho, Wendy W. T. Lam +1 more

    2022Nutrition and Cancer1 citations

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43. Abstract 1777: Development of a pan-cancer 15 gene expression signature to detect a subgroup driven by MAPK signalling

    L. Knight, B. Price, A. McCavigan, A. El Helali +4 more

    20171 citations

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44. Abstract 776: Acquired platinum resistance enhances tumour angiogenesis through activation of vascular mimicry

    A. El Helali, N. Mccabe, Naomi Dickson, Lara Dura Perez +3 more

    20171 citations

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45. Abstract 1018: Longitudinal peripheral blood TCR tracking predicts response to immune checkpoint inhibitors.

    Dingyuan Wang, Kaiyan Xu, Parker Li, D. Shih +4 more

    2026Cancer Research0 citations

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46. Safety and Effectiveness of Direct Oral Anticoagulants Versus Low-Molecular-Weight Heparin for Cancer-Associated Thrombosis: A Systematic Review and Meta-analysis

    W. Kang, Bowie P. Lam, R. Lau, Silvia T. H. Li +14 more

    2026Drug Safety0 citations Open access

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47. The ESMO Scale for Clinical Actionability of Molecular Targets, version 2 (ESCAT v2): an evidence-based framework for ranking alterations as actionability and resistance biomarkers in precision oncology.

    A. El Helali, C. Cardone, N. Coleman, J. Beal +19 more

    2026Annals of Oncology0 citations Open access

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48. Abstract 6206: Spatially resolved cell-cell architecture in WHO grade 4 IDH- wildtype glioblastoma revealed by CosMx 6K discovery panel

    Dexter Wing Lun Lee, Kaiyan Xu, Parker Li, Joshua Jing Xi Li +4 more

    2026Cancer Research0 citations

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49. Multi‐parametric MRI synthesis for glioblastoma from quantitative MR fingerprinting: Quantitative synthetic neural network (QS‐Net)

    Yimin Ni, Chen-Yang Liu, Wen Li, Ling Lin +10 more

    2026Medical Physics (Lancaster)0 citations Open access

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50. Glutamate Carboxypeptidase II (GCPII)-Targeted PET to Identify Muscle Denervation in Peripheral Nervous System Injuries

    W. Padovano, R. Suresh, E. K. Rowley, A. Weitzner +16 more

    2026medRxiv0 citations

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