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S. Okret · SciRah

Researcher profile · Semantic Scholar

S. Okret

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S. Okret — researcher profile on SciRah

h-index: 55
Works: 148
Citations: 11K

Most-cited papers

Negative cross-talk between RelA and the glucocorticoid receptor: a possible mechanism for the antiinflammatory action of glucocorticoids.
E. Caldenhoven, J. Lidén, S. Wissink, A. van de Stolpe +5 more
1995Molecular Endocrinology522 citations Open access
Semantic Scholar
Pancreatic beta cells are important targets for the diabetogenic effects of glucocorticoids.
F. Delaunay, Akhtar Khan, A. Cintra, B. Davani +6 more
1997Journal of Clinical Investigation356 citations Open access
Semantic Scholar
Mapping and computer assisted morphometry and microdensitometry of glucocorticoid receptor immunoreactive neurons and glial cells in the rat central nervous system.
A. Cintra, M. Zoli, L. Rosén, L. Agnati +4 more
1994Neuroscience174 citations
Semantic Scholar
A New Function for the C-terminal Zinc Finger of the Glucocorticoid Receptor
J. Lidén, F. Delaunay, I. Rafter, Jan-Åke Gustafsson +1 more
1997Journal of Biological Chemistry165 citations Open access
Semantic Scholar
p57Kip2 cooperates with Nurr1 in developing dopamine cells
B. Joseph, Åsa Wallén-Mackenzie, G. Benoit, T. Murata +3 more
2003Proceedings of the National Academy of Sciences of the United States of America161 citations Open access
Semantic Scholar
The mechanism of cAMP-induced glucocorticoid receptor expression. Correlation to cellular glucocorticoid response.
Yu Dong, Marie Aronsson, Jan-åke Gustafsson, S. Okret
1989Journal of Biological Chemistry136 citations Open access
Semantic Scholar
Paracrine glucocorticoid activity produced by mouse thymic epithelial cells
A. Pazirandeh, Yi-Le Xue, I. Rafter, J. Sjövall +2 more
1999The FASEB Journal128 citations
Semantic Scholar
Type 1 11β-Hydroxysteroid Dehydrogenase Mediates Glucocorticoid Activation and Insulin Release in Pancreatic Islets*
B. Davani, Akhtar Khan, M. Hult, Eva Mårtensson +4 more
2000Journal of Biological Chemistry118 citations Open access
Semantic Scholar
Receptor Interacting Protein RIP140 Inhibits Both Positive and Negative Gene Regulation by Glucocorticoids*
Nanthakumar Subramaniam, E. Treuter, S. Okret
1999Journal of Biological Chemistry106 citations Open access
Semantic Scholar
Effects of altered glucocorticoid sensitivity in the T‐cell lineage on thymocyte and T‐cell homeostasis
A. Pazirandeh, Yi-Le Xue, T. Prestegaard, M. Jondal +1 more
2002The FASEB Journal103 citations
Semantic Scholar
p57Kip2, a glucocorticoid-induced inhibitor of cell cycle progression in HeLa cells.
M. Samuelsson, A. Pazirandeh, B. Davani, S. Okret
1999Molecular Endocrinology100 citations Open access
Semantic Scholar
Glucocorticoid Effects on NF-κB Binding in the Transcription of the ICAM-1 Gene☆
J. Lidén, I. Rafter, M. Truss, J. Gustafsson +1 more
200090 citations
Semantic Scholar
Estrogen receptor α and β in the normal immune system and in lymphoid malignancies.
K. Yakimchuk, M. Jondal, S. Okret
2013Molecular and Cellular Endocrinology88 citations
Semantic Scholar
Aged transgenic mice with increased glucocorticoid sensitivity in pancreatic beta-cells develop diabetes.
B. Davani, N. Portwood, G. Bryzgalova, M. Reimer +6 more
2004Diabetes88 citations Open access
Semantic Scholar
Different roles for glucocorticoids in thymocyte homeostasis?
M. Jondal, A. Pazirandeh, S. Okret
2004Trends in immunology85 citations
Semantic Scholar
Prenatal development of glucocorticoid receptor gene expression and immunoreactivity in the rat brain and pituitary gland: a combined in situ hybridization and immunocytochemical analysis.
A. Cintra, V. Solfrini, B. Bunnemann, S. Okret +3 more
1993Neuroendocrinology85 citations
Semantic Scholar
Central peptidergic neurons as targets for glucocorticoid action. Evidence for the presence of glucocorticoid receptor immunoreactivity in various types of classes of peptidergic neurons.
A. Cintra, K. Fuxe, V. Solfrini, L. Agnati +5 more
1991Journal of Steroid Biochemistry and Molecular Biology84 citations
Semantic Scholar
Effect of ligand-activated estrogen receptor β on lymphoma growth in vitro and in vivo
K. Yakimchuk, M. Iravani, M. S. Hasni, P. Rhönnstad +3 more
2011Leukemia80 citations Open access
Semantic Scholar
Killing of immature CD4+CD8+ thymocytes in vivo by anti‐CD3 or 5′‐(N‐ethyl)‐carboxamido‐adenosine is blocked by glucocorticoid receptor antagonist RU‐486
M. Jondal, S. Okret, D. McConkey
1993European Journal of Immunology79 citations
Semantic Scholar
Cross-talk between steroids and NF-κB: what language?
A. Dumont, S. Hehner, M. Schmitz, Jan-åke Gustafsson +9 more
199878 citations
Semantic Scholar
Glucocorticoids Repress Transcription from a Negative Glucocorticoid Response Element Recognized by Two Homeodomain-containing Proteins, Pbx and Oct-1*
Nanthakumar Subramaniam, W. Cairns, S. Okret
1998Journal of Biological Chemistry78 citations Open access
Semantic Scholar
Extra-adrenal glucocorticoid synthesis: immune regulation and aspects on local organ homeostasis.
G. Talabér, M. Jondal, S. Okret
2013Molecular and Cellular Endocrinology70 citations Open access
Semantic Scholar
Increased glucocorticoid sensitivity in islet beta-cells: effects on glucose 6-phosphatase, glucose cycling and insulin release
Zong-Chao Ling, A. Khan, F. Delauny, B. Davani +5 more
1998Diabetologia67 citations Open access
Semantic Scholar
Inhibition of Gene Expression by Steroid Hormone Receptors Via a Negative Glucocorticoid Response Element: Evidence for the Involvement of DNA-Binding and Agonistic Effects of the Antiglucocorticoid/Antiprogestin RU486
C. Cairns, W. Cairns, S. Okret
1993DNA and Cell Biology66 citations
Semantic Scholar
Steroid and nuclear receptors Villefranche‐sur‐Mer, France, May 25–27, 1999
L. Di Croce, S. Okret, S. Kersten, Jan-åke Gustafsson +3 more
1999EMBO Journal65 citations Open access
Semantic Scholar
Regional differences in glucocorticoid receptor immunoreactivity among neuropeptide Y immunoreactive neurons of the rat brain.
A. Härfstrand, A. Cintra, K. Fuxe, M. Aronsson +4 more
1989Acta Physiologica Scandinavica64 citations
Semantic Scholar
Stimulation of MAPK-phosphatase 1 gene expression by glucocorticoids occurs through a tethering mechanism involving C/EBP.
K. Johansson-Haque, Elanchelian Palanichamy, S. Okret
2008Journal of Molecular Endocrinology62 citations Open access
Semantic Scholar
Inhibition of lymphoma vascularization and dissemination by estrogen receptor β agonists.
K. Yakimchuk, M. S. Hasni, Jiyu Guan, Mark P. Chao +2 more
2014Blood61 citations Open access
Semantic Scholar
Dickkopf 1 mediates glucocorticoid-induced changes in human neural progenitor cell proliferation and differentiation.
M. Moors, R. Bose, K. Johansson-Haque, K. Edoff +2 more
2012Toxicological Sciences61 citations
Semantic Scholar
Cyclic AMP potentiates glucocorticoid‐induced endogenous endonuclease activation in thymocytes 1
D. J. McConkey, S. Orrenius, S. Okret, M. Jondal
1993The FASEB Journal58 citations
Semantic Scholar
Assembly of a glucocorticoid receptor complex prior to DNA binding enhances its specific interaction with a glucocorticoid response element.
William Cairns, C. Cairns, I. Pongratz, L. Poellinger +1 more
1991Journal of Biological Chemistry58 citations Open access
Semantic Scholar
Age-related synthesis of glucocorticoids in thymocytes.
Sheng-Jun Qiao, Liying Chen, S. Okret, M. Jondal
2008Experimental Cell Research56 citations Open access
Semantic Scholar
Identification of Endogenous Glucocorticoid Repressed Genes Differentially Regulated by a Glucocorticoid Receptor Mutant Able to Separate between Nuclear Factor-κB and Activator Protein-1 Repression
L. Bladh, J. Lidén, K. Dahlman-Wright, M. Reimers +2 more
2004Molecular Pharmacology55 citations
Semantic Scholar
Expression Level-Dependent Contribution of Glucocorticoid Receptor Domains for Functional Interaction with STAT5
W. Doppler, M. Windegger, Claudia Soratroi, Jürgen K. Tomasi +12 more
2001Molecular and Cellular Biology55 citations Open access
Semantic Scholar
Thymus‐derived glucocorticoids mediate androgen effects on thymocyte homeostasis
Yong-Wen Chen, Sheng-Jun Qiao, J. Tuckermann, S. Okret +1 more
2010The FASEB Journal50 citations Open access
Semantic Scholar
Identification of a functional glucocorticoid response element in the promoter of the cyclin-dependent kinase inhibitor p57Kip2.
K. Alheim, J. Corness, M. Samuelsson, L. Bladh +3 more
2003Journal of Molecular Endocrinology48 citations Open access
Semantic Scholar
Ethyl pyruvate modulates acute inflammatory reactions in human endothelial cells in relation to the NF‐κB pathway
Anne-Sofie Johansson, K. Johansson-Haque, S. Okret, J. Palmblad
2008British Journal of Pharmacology47 citations Open access
Semantic Scholar
Identification of target genes involved in the antiproliferative effect of glucocorticoids reveals a role for nuclear factor-(kappa)B repression.
L. Bladh, J. Lidén, A. Pazirandeh, I. Rafter +3 more
2005Molecular Endocrinology47 citations Open access
Semantic Scholar
Nuclear Factor-κ B Repression in Antiinflammation and Immunosuppression by Glucocorticoids
B. van der Burg, J. Lidén, S. Okret, F. Delaunay +3 more
199747 citations
Semantic Scholar
Conditional expression of a glucocorticoid receptor transgene in thymocytes reveals a role for thymic-derived glucocorticoids in thymopoiesis in vivo.
A. Pazirandeh, M. Jondal, S. Okret
2005Endocrinology46 citations
Semantic Scholar
A pro-apoptotic effect of the CDK inhibitor p57(Kip2) on staurosporine-induced apoptosis in HeLa cells.
M. Samuelsson, A. Pazirandeh, S. Okret
2002Biochemical and Biophysical Research Communications - BBRC45 citations
Semantic Scholar
Studies on the Mechanism of Glucocorticoid-Mediated Repression from a Negative Glucocorticoid Response Element from the Bovine Prolactin Gene
Nanthakumar Subramaniam, William Cairns, S. Okret
1997DNA and Cell Biology43 citations
Semantic Scholar
Thymocyte-synthesized glucocorticoids play a role in thymocyte homeostasis and are down-regulated by adrenocorticotropic hormone.
Sheng-Jun Qiao, S. Okret, M. Jondal
2009Endocrinology42 citations
Semantic Scholar
Inhibition of extracellular signal-regulated kinase (ERK) signaling participates in repression of nuclear factor (NF)-kappaB activity by glucocorticoids.
L. Bladh, K. Johansson-Haque, I. Rafter, S. Nilsson +1 more
2009Biochimica et Biophysica Acta36 citations Open access
Semantic Scholar
Inhibition of I‐Ad‐, but not Db‐restricted peptide‐induced thymic apoptosis by glucocorticoid receptor antagonist RU486 in T cell receptor transgenic mice
Yi-Le Xue, M. Murdjeva, S. Okret, D. McConkey +2 more
1996European Journal of Immunology36 citations
Semantic Scholar
Glucocorticoid effects on NF-kappaB binding in the transcription of the ICAM-1 gene.
J. Lidén, I. Rafter, M. Truss, J. Gustafsson +1 more
2000Biochemical and Biophysical Research Communications - BBRC35 citations
Semantic Scholar
Cross-talk between glucocorticoid and retinoic acid signals involving glucocorticoid receptor interaction with the homoeodomain protein Pbx1.
Nanthakumar Subramaniam, J. Campión, I. Rafter, S. Okret
2003Biochemical Journal33 citations Open access
Semantic Scholar
Functional glucocorticoid receptor expression is required for cAMP-mediated apoptosis in a human leukemic T cell line.
Jeff Kiefer, S. Okret, Mikael Jondal, D. J. McConkey
1995Journal of Immunology33 citations
Semantic Scholar
The glucocorticoid receptor in the adrenal gland is localized in the cytoplasm of adrenaline cells.
Sandra Ceccatelli, Åke Dagerlind, M. Schalling, A. Wikström +4 more
1989Acta Physiologica Scandinavica32 citations
Semantic Scholar
Glucocorticoids delay age-associated thymic involution through directly affecting the thymocytes.
A. Pazirandeh, M. Jondal, S. Okret
2004Endocrinology31 citations Open access
Semantic Scholar

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