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H. Nakase · SciRah

Researcher profile · Semantic Scholar

H. Nakase

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H. Nakase — researcher profile on SciRah

h-index: 54
Works: 530
Citations: 14K

Most-cited papers

Upadacitinib as induction and maintenance therapy for moderately to severely active ulcerative colitis: results from three phase 3, multicentre, double-blind, randomised trials.
S. Danese, S. Vermeire, Wen Zhou, A. Pangan +19 more
2022The Lancet487 citations Open access
Semantic Scholar
Evidence-based clinical practice guidelines for inflammatory bowel disease 2020
H. Nakase, M. Uchino, S. Shinzaki, M. Matsuura +20 more
2021Journal of gastroenterology459 citations Open access
Semantic Scholar
The influence of cytokines on the complex pathology of ulcerative colitis.
H. Nakase, N. Sato, Naomi Mizuno, Yoshiko Ikawa
2021Autoimmunity Reviews410 citations Open access
Semantic Scholar
Upadacitinib Induction and Maintenance Therapy for Crohn's Disease.
E. Loftus, J. Panés, A. Lacerda, L. Peyrin-Biroulet +15 more
2023New England Journal of Medicine353 citations Open access
Semantic Scholar
The Molecular Mechanisms of Intestinal Inflammation and Fibrosis in Crohn’s Disease
Yuki Hayashi, H. Nakase
2022Frontiers in Physiology45 citations Open access
Semantic Scholar
The characteristics of gastrointestinal symptoms in patients with severe COVID-19: a systematic review and meta-analysis
Yuki Hayashi, Kohei Wagatsuma, M. Nojima, Tsukasa Yamakawa +5 more
2021Journal of gastroenterology45 citations Open access
Semantic Scholar
Guidelines for endoscopic balloon dilation in treating Crohn's disease‐associated small intestinal strictures (supplement to the Clinical Practice Guidelines for Enteroscopy)
H. Yamamoto, T. Yano, A. Araki, M. Esaki +16 more
2022Digestive Endoscopy42 citations Open access
Semantic Scholar
Role of Biomarkers in the Diagnosis and Treatment of Inflammatory Bowel Disease
Kohei Wagatsuma, Y. Yokoyama, H. Nakase
2021Life42 citations Open access
Semantic Scholar
Diagnosis and Clinical Features of Perianal Lesions in Newly Diagnosed Crohn’s Disease: Subgroup Analysis from Inception Cohort Registry Study of Patients with Crohn’s Disease (iCREST-CD)
Takayuki Yamamoto, H. Nakase, Kenji Watanabe, S. Shinzaki +24 more
2023Journal of Crohn's & Colitis38 citations Open access
Semantic Scholar
Efficacy and safety of upadacitinib maintenance therapy for moderately to severely active ulcerative colitis in patients responding to 8 week induction therapy (U-ACHIEVE Maintenance): overall results from the randomised, placebo-controlled, double-blind, phase 3 maintenance study.
S. Vermeire, S. Danese, Wen Zhou, D. Ilo +13 more
2023The Lancet Gastroenterology and Hepatology36 citations
Semantic Scholar
Acute Severe Ulcerative Colitis: Optimal Strategies for Drug Therapy
H. Nakase
2022Gut and Liver36 citations Open access
Semantic Scholar
Synergistic effect of IFN-γ and IL-1β on PD-L1 expression in hepatocellular carcinoma
Y. Numata, N. Akutsu, Keisuke Ishigami, Hideyuki Koide +4 more
2022Biochemistry and Biophysics Reports32 citations Open access
Semantic Scholar
Snapshots of lymphatic pathways in colorectal cancer surgery using near-infrared fluorescence, in vivo and ex vivo.
Yu Sato, Tetsuta Satoyoshi, K. Okita, D. Kyuno +10 more
2021European Journal of Surgical Oncology31 citations
Semantic Scholar
The clinical efficacy of azathioprine as maintenance treatment for autoimmune pancreatitis: a systematic review and meta-analysis
Yoshiharu Masaki, H. Nakase, Y. Tsuji, M. Nojima +10 more
2021Journal of gastroenterology29 citations Open access
Semantic Scholar
Characteristics of adult patients newly diagnosed with Crohn’s disease: interim analysis of the nation-wide inception cohort registry study of patients with Crohn’s disease in Japan (iCREST-CD)
K. Matsuoka, T. Fujii, R. Okamoto, A. Yamada +24 more
2022Journal of gastroenterology28 citations
Semantic Scholar
TM4SF1-AS1 inhibits apoptosis by promoting stress granule formation in cancer cells
Hiroshi Kitajima, R. Maruyama, T. Niinuma, E. Yamamoto +19 more
2023Cell Death and Disease24 citations Open access
Semantic Scholar
Elevated Myl9 reflects the Myl9-containing microthrombi in SARS-CoV-2–induced lung exudative vasculitis and predicts COVID-19 severity
C. Iwamura, K. Hirahara, M. Kiuchi, Sanae Ikehara +45 more
2022Proceedings of the National Academy of Sciences of the United States of America19 citations Open access
Semantic Scholar
Both fecal calprotectin and fecal immunochemical tests are useful in children with inflammatory bowel disease
H. Shimizu, R. Ebana, T. Kudo, Takuro Sato +9 more
2022Journal of gastroenterology18 citations
Semantic Scholar
Extensive mucosal sloughing of the small intestine and colon in a patient with severe COVID‐19
Tsukasa Yamakawa, Keisuke Ishigami, Ayumu Takizawa, Yumemi Takada +14 more
2021DEN Open16 citations Open access
Semantic Scholar
Regional Transcriptomics and Proteomics of Pharmacokinetics-Related Genes in Human Intestine.
Michika Murata, Hijiri Fujioka, Jumpei Yokota, Kentaro Okada +8 more
2023Molecular Pharmaceutics15 citations
Semantic Scholar
Adrenomedullin for biologic‐resistant Crohn's disease: A randomized, double‐blind, placebo‐controlled phase 2a clinical trial
T. Kita, S. Ashizuka, T. Takeda, T. Matsumoto +17 more
2022Journal of Gastroenterology and Hepatology14 citations Open access
Semantic Scholar
Understanding the efficacy of individual Janus kinase inhibitors in the treatment of ulcerative colitis for future positioning in inflammatory bowel disease treatment
H. Nakase
2023Immunological Medicine13 citations Open access
Semantic Scholar
Immune-related colitis and pancreatitis treated with infliximab
Sae Ohwada, Keisuke Ishigami, Y. Yokoyama, Tomoe Kazama +6 more
2022Clinical Journal of Gastroenterology13 citations
Semantic Scholar
Pharmacological Treatments Available for Immune-Checkpoint-Inhibitor-Induced Colitis
Sae Ohwada, Keisuke Ishigami, N. Akutsu, H. Nakase
2022Biomedicines11 citations Open access
Semantic Scholar
Impaired tryptophan metabolism in the gastrointestinal tract of patients with critical coronavirus disease 2019
Y. Yokoyama, T. Ichiki, Tsukasa Yamakawa, Y. Tsuji +4 more
2022Frontiers in Medicine11 citations Open access
Semantic Scholar
Anxiety and behavioral changes in Japanese patients with inflammatory bowel disease due to COVID-19 pandemic: a national survey
H. Nakase, Kohei Wagatsuma, M. Nojima, T. Matsumoto +30 more
2023Journal of gastroenterology10 citations Open access
Semantic Scholar
Comparison of culture media for human intestinal organoids from the viewpoint of pharmacokinetic studies.
Jumpei Yokota, T. Yamashita, T. Inui, Ryuga Nomoto +3 more
2021Biochemical and Biophysical Research Communications - BBRC10 citations Open access
Semantic Scholar
Concomitant use of an immunomodulator with ustekinumab as an induction therapy for Crohn's disease: A systematic review and meta‐analysis
T. Yoshihara, S. Shinzaki, Takahiro Amano, H. Iijima +17 more
2021Journal of Gastroenterology and Hepatology10 citations
Semantic Scholar
Application of plasma alternative to serum for measuring leucine-rich α2-glycoprotein as a biomarker of inflammatory bowel disease
T. Ichimiya, Tomoe Kazama, Keisuke Ishigami, Y. Yokoyama +4 more
2023PLoS ONE9 citations Open access
Semantic Scholar
Gel immersion endoscopic mucosal resection for early gastric cancer near the pyloric ring.
K. Miura, G. Sudo, Mitsunobu Saito, Kazunori Onuma +3 more
2022Endoscopy9 citations Open access
Semantic Scholar
Establishment of MDR1-knockout human enteroids for pharmaceutical application.
T. Inui, Ryuga Nomoto, Jumpei Yokota, T. Yamashita +4 more
2022Drug Metabolism and Pharmacokinetics9 citations Open access
Semantic Scholar
P573 The safety profile of upadacitinib maintenance therapy in ulcerative colitis in the Phase 3 U-ACHIEVE study is consistent with that in approved indications
J. Colombel, R. Panaccione, H. Nakase, G. Burmester +7 more
2022Journal of Crohn's & Colitis8 citations
Semantic Scholar
Dead or alive? Pitfall of survival analysis with TCGA datasets
M. Idogawa, M. Koizumi, T. Hirano, S. Tange +2 more
2021Cancer Biology & Therapy8 citations Open access
Semantic Scholar
867f: EFFICACY AND SAFETY OF UPADACITINIB INDUCTION THERAPY IN PATIENTS WITH MODERATELY TO SEVERELY ACTIVE CROHN'S DISEASE WHO FAILED PRIOR BIOLOGICS: RESULTS FROM A RANDOMIZED PHASE 3 U-EXCEED STUDY
J. Colombel, J. Panés, A. Lacerda, L. Peyrin-Biroulet +13 more
2022Gastroenterology7 citations
Semantic Scholar
Effectiveness and safety of gemcitabine plus nab-paclitaxel in elderly patients with advanced pancreatic cancer: a single-center retrospective cohort study
Sae Ohwada, A. Todaka, H. Nakase, H. Shirasu +7 more
2022Investigational new drugs7 citations
Semantic Scholar
Direct clipping using underwater inversion method for colonic diverticular bleeding
Mitsunobu Saito, G. Sudo, Shun Takai, Atsushi Yawata +1 more
2022VideoGIE7 citations Open access
Semantic Scholar
Comparison of human biopsy-derived and human iPS cell-derived intestinal organoids established from a single individual.
T. Inui, T. Yamashita, J. Tomita, Jumpei Yokota +3 more
2022Drug Metabolism and Pharmacokinetics7 citations Open access
Semantic Scholar
Serum amyloid A1 recruits neutrophils to the invasive front of T1 colorectal cancers
Ayano Yoshido, G. Sudo, Akira Takasawa, Hironori Aoki +14 more
2022Journal of Gastroenterology and Hepatology7 citations
Semantic Scholar
Genomic analysis of an aggressive case with metastatic intrahepatic mucinous cholangiocarcinoma
Yoshiharu Masaki, N. Akutsu, Y. Adachi, K. Ishigami +7 more
2022Clinical Journal of Gastroenterology6 citations
Semantic Scholar
Novel injectable needle‐type knife, ProKnife for colorectal endoscopic submucosal dissection
S. Yoshii, H. Yamano, H. Nakase
2021Digestive Endoscopy6 citations
Semantic Scholar
Mediterranean fever gene-associated enterocolitis in an elderly Japanese woman
Y. Shibata, Keisuke Ishigami, Tomoe Kazama, T. Kubo +4 more
2021Clinical Journal of Gastroenterology6 citations
Semantic Scholar
DOP24 Japan prospective multicenter study for optimization of COVID-19 vaccinations based on the immune response and safety profile in Inflammatory Bowel Disease patients: Interim analyses of the J-COMBAT trial
K. Watanabe, T. Hisamatsu, H. Nakase, K. Nagase +33 more
2022Journal of Crohn's & Colitis5 citations Open access
Semantic Scholar
Sclerosing Epithelioid Mesenchymal Neoplasm of the Pancreas
M. Shitani, J. Ogino, Mai Isosaka, Mikino Ito +7 more
2021Pancreas5 citations Open access
Semantic Scholar
Sustained Eosinophilic Cholangitis Due to a Mite Allergy Mimicking Sclerosing Cholangitis
Masayo Motoya, Shun Takai, H. Moriya, Takehiro Hirano +7 more
2022Internal medicine4 citations Open access
Semantic Scholar
S736 Efficacy and Safety of Upadacitinib Induction Therapy in Patients With Moderately to Severely Active Crohn’s Disease: Results From a Randomized Phase 3 U-EXCEL Study
E. Loftus, J. Colombel, A. Lacerda, L. Peyrin-Biroulet +14 more
2022American Journal of Gastroenterology4 citations
Semantic Scholar
A Case of Immunoglobulin G4-Related Gastrointestinal Disease Diagnosed From Persistent Diarrhea and Abdominal Pain
Takehiro Hirano, Yujiro Kawakami, Sayaka Nakabayashi, Kohei Wagatsuma +7 more
2023Gastro Hep Advances3 citations Open access
Semantic Scholar
Pancreatic ductal adenocarcinomas concomitant with intraductal papillary mucinous neoplasms of the pancreas: A investigation of those clinicopathological features by analyzing 48 patients who underwent surgery for those lesions.
Yujiro Kawakami, Shinsuke Koshita, Yoshihide Kanno, Takahisa Ogawa +12 more
2023Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]3 citations
Semantic Scholar
S805 Efficacy of Upadacitinib Dose Escalation in a Phase 3 Long-Term Extension Ulcerative Colitis Study
R. Panaccione, Millie D. Long, Z. Ran, R. Atreya +5 more
2022American Journal of Gastroenterology3 citations
Semantic Scholar
Remitting Seronegative Symmetrical Synovitis with Pitting Edema (RS3PE) Syndrome Precedes the Development of Hepatocellular Carcinoma
Sae Ohwada, N. Akutsu, Yoshiharu Masaki, S. Sasaki +5 more
2022JMA Journal3 citations Open access
Semantic Scholar
Jejunal Angiodysplasia in an Elderly Patient with Aortic Stenosis: Significance of Von Willebrand Factor as an Etiologic Factor
T. Kubo, S. Yoshii, H. Yamano, Masato Saito +5 more
2022Internal medicine3 citations Open access
Semantic Scholar

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