W. Besch

Most-cited papers

1. Alteration of pancreatic B-cells in Wistar rats treated with non-diabetogenic doses of cyclosporin A.

   H. Hahn, R. Laube, S. Lucke, W. Besch

   1992Acta Pharmacologica et Toxicologica45 citations

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2. Measurement of Insulin in Human Sera Using a New RIA Kit. 1. Insulin Determination in the Absence of Insulin Antibodies — Conventional Assay and Micro Modification2)

   W. Besch, K.-P. Woltanski, H. Keilacker, J. Diaz-Alonso +4 more

   1987Experimental and clinical endocrinology31 citations

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3. Reversibility of the acute toxic effect of Cyclosporin A on pancreatic B cells of Wistar rats

   H. Hahn, A. Dunger, F. Laube, W. Besch +3 more

   1986Diabetologia23 citations Open access

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4. Autoantibodies to insulin and to proinsulin in type 1 diabetic patients and in at-risk probands differentiate only little between both antigens.

   H. Keilacker, I. Rjasanowski, W. Besch, K. Kohnert

   1995Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme21 citations

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5. Measurement Of Insulin in Human Sera Using a New RIA Kit. 2. Determination of Free and Total Insulin — Correlations to Insulin Antibody Levels1)

   H. Keilacker, W. Besch, K. P. Woltanski, J. Diaz-Alonso +2 more

   1987Experimental and clinical endocrinology21 citations

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6. Radioiodination of peptide hormones and immunoglobulin preparations: comparison of the chloramine T and iodogen method.

   K. Woltanski, W. Besch, H. Keilacker, M. Ziegler +1 more

   2009Experimental and clinical endocrinology19 citations

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7. The Endocrine Pancreas of BB/OK-Rats before and at Diagnosis of Hyperglycaemia

   S. Lucke, W. Besch, C. Kauert, H. Hahn

   1988Experimental and clinical endocrinology19 citations

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8. Spontaneous recovery of streptozotocin diabetes in mice.

   K. Hartmann, W. Besch, H. Zuhlke

   2009Experimental and clinical endocrinology18 citations

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9. A Sensitive Sandwich Enzyme Immunoassay for Measurement of Insulin on Microtiter Plates

   J. Kratzsch, W. Ackermann, H. Keilacker, W. Besch +1 more

   1990Experimental and clinical endocrinology18 citations

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10. Assessment of an algorithm for the artificial B-cell using the normal insulin-glucose relationship in diabetic dogs and men

    U. Fischer, E. Jutzi, H. Bombor, E. Freyse +4 more

    2004Diabetologia16 citations Open access

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11. Serum magnesium in insulin-dependent diabetics and healthy subjects in relation to insulin secretion and glycemia during glucose-glucagon test.

    R. Menzel, H. Pusch, G. W. Ratzmann, W. Besch +3 more

    2009Experimental and clinical endocrinology15 citations

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12. Muscular exercise in type I-diabetics. I. Different metabolic reactions during heavy muscular work in dependence on actual insulin availability.

    E. Zander, W. Bruns, P. Wulfert, W. Besch +3 more

    2009Experimental and clinical endocrinology15 citations

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13. Indication and results of insulin therapy for gestational diabetes mellitus

    H. Hopp, W. Vollert, V. Ragosch, A. Novak +3 more

    1996Journal of Perinatal Medicine15 citations

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14. Insulin Antibodies in Juvenile Diabetes Mellitus

    H. Keilacker, I. Rjasanowski, M. Ziegler, D. Michaelis +2 more

    1982Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme15 citations

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15. Monoclonal antibody-mediated cytotoxicity against rat Beta cells detected in vitro does not cause Beta-cell destruction in vivo

    B. Ziegler, Silke Lucke, E. Köhler, B. Hehmke +4 more

    1992Diabetologia14 citations Open access

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16. The encapsulation of pancreatic islets. Investigation of insulin secretion and content in vitro.

    K. Braun, W. Besch, H. Jahr, F. Loth +2 more

    1985Biomedica biochimica acta13 citations

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17. Tolbutamide does not alter insulin requirement in Type 1 (insulin-dependent) diabetes

    K. Ratzmann, B. Schulz, P. Heinke, W. Besch

    1984Diabetologia13 citations Open access

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18. 5-Year Follow-up Study of C-Peptide Secretion in Newly Diagnosed Type I Diabetics: Relations to HLA- Phenotype, Insulin Requirement and Metabolic Control

    Ilona M. Rjasanowski, D. Michaelis, H. Keilacker, W. Besch +2 more

    2009Experimental and clinical endocrinology11 citations

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19. The effect of potassium, calcium and magnesium concentration on insulin and glucagon secretion of the perfused dog pancreas.

    E. Panzig, W. Besch, K. Rosenbaum, W. Tietz +3 more

    2009Experimental and clinical endocrinology11 citations

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20. Intraindividual Comparison of Pharmacokinetics of Insulin after Intravenous, Portal, Subcutaneous and Peritoneal Administration

    Kathrin Fritze, U. Fischer, E. Freyse, W. Besch

    1988Experimental and clinical endocrinology11 citations

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21. Characterization of pseudo-islets formed from pancreatic islet cell suspensions of neonatal rats.

    D. Schröder, U. Wegner, W. Besch, H. Zuhlke

    1983Molecular and Cellular Endocrinology11 citations

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22. Effects of islet transplantation on the recipient endocrine pancreas.

    H. Hahn, S. Lucke, B. Ziegler, W. Besch +1 more

    1985Biomedica biochimica acta10 citations

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23. Enhanced synthesis, storage, and secretion of insulin in pancreatic islets derived from obese subjects.

    H. Jahr, K. Ratzmann, R. Beckert, W. Besch +1 more

    1983Metabolism: Clinical and Experimental10 citations

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24. Absorption rates of subcutaneously injected insulin in the dog as calculated from the plasma insulin levels by means of a simple mathematical model

    U. Fischer, E. Freyse, E. Jutzi, W. Besch +3 more

    1983Diabetologia9 citations Open access

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25. Evaluation of insulin resistance during inhibition of endogenous insulin and glucagon secretion by somatostatin in non-obese subjects with impaired glucose tolerance

    K. Ratzmann, W. Besch, S. Witt, B. Schulz

    1981Diabetologia9 citations Open access

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26. The long-term culture of encapsulated pancreatic islets.

    K. Braun, W. Besch, S. Lucke, H. Hahn

    2009Experimental and clinical endocrinology8 citations

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27. Erythrocyte sodium-lithium countertransport, adenosine triphosphatase activity and sodium-potassium fluxes in insulin-dependent diabetes

    W. Besch, H. Blucher, D. Bettin, E. Wolf +2 more

    1995International journal of clinical & laboratory research (Print)8 citations

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28. The effects of subdiabetogenic streptozotocin doses on rat beta cell volume and functions.

    S. Lucke, B. Ziegler, K. Weidlich, U. Barowski +2 more

    1985Biomedica biochimica acta8 citations

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29. Prospective investigations of long-term normoglycaemic BB/OK-rats: serial determination of glucose tolerance, insulitis, B-cell volume density and pancreatic insulin content.

    H. Hahn, S. Lucke, I. Kloting, W. Besch

    2009Experimental and clinical endocrinology7 citations

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30. Survival of islet isografts despite cytotoxicity against pancreatic islets measured in vitro.

    Brigitte Ziegler, E. Köhler, I. Klöting, W. Besch +1 more

    2009Experimental and clinical endocrinology6 citations

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31. Measurement of plasma canine C-peptide by radioimmunoassay.

    W. Besch, K.-P. Woltanski, U. Fischer, K. Kohnert +1 more

    2009Experimental and clinical endocrinology6 citations

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32. A stimulatory effect of tolbutamide on the insulin-mediated glucose uptake in subjects with impaired glucose tolerance (IGT).

    B. Schulz, K. Ratzmann, P. Heinke, W. Besch

    2009Experimental and clinical endocrinology6 citations

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33. Humoral-mediated anti-islet cytotoxicity in diabetes-prone BB/OK rats--effect on beta-cell function and autologous islets.

    D. Schröder, B. Hehmke, I. Klöting, W. Besch +1 more

    2009Experimental and clinical endocrinology6 citations

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34. Validation of Red Cell Sodium-Lithium Countertransport Measurement — Influence of Different Loading Conditions

    W. Besch, Doreen Schläger, J. Brahm, K. Kohnert

    1995European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies6 citations Open access

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35. Extended survival of MHC-identical allogeneic islet grafts in diabetic BB rats--the effect of an interleukin 2 receptor-targeted immunotherapy.

    H. Hahn, B. Kuttler, I. Kloting, A. Dunger +2 more

    1992Transplantation6 citations Open access

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36. [Phase contrast microscopy demonstration of glomerular erythrocytes in urine: practicable in ambulatory practice?].

    M. Conzelmann, D. Conen, W. Besch, U. Dubach +1 more

    1988Swiss medical weekly6 citations

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37. Cytotoxic activity of sera from diabetic BB rats against BB rat islet--a functional study.

    B. Ziegler, I. Kloting, W. Besch, M. Ziegler +1 more

    1987Diabetes research (Edinburgh, Scotland)6 citations

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38. Pregnancy-associated changes in the endocrine pancreas of normoglycaemic streptozotocin-treated Wistar rats

    B. Ziegler, S. Lucke, W. Besch, H. Hahn

    1985Diabetologia6 citations Open access

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39. Canine C-peptide for characterization of experimental diabetes in dogs.

    U. Fischer, W. Besch, E. Freyse

    1985Endocrinologia experimentalis6 citations

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40. Effect of serum from diabetes-prone BB/OK rats on neonatal rat pancreatic islets and islet cell suspensions.

    D. Schröder, B. Hehmke, I. Klöting, W. Besch

    2009Experimental and clinical endocrinology5 citations

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41. The in Vitro Insulin Secretion of Human Fetal Pancreatic Slices from Diabetic and Non-diabetic Women — a Methodical Study

    H. Reiher, K. Fuhrmann, S. Noack, W. Besch +1 more

    1984Experimental and clinical endocrinology5 citations

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42. Discrepant Effect of the Prostaglandin Synthesis Inhibitor Acetylsalicylic Acid on Insulin and C-Peptide Response to Glucose in Man

    K. Ratzmann, W. Besch, S. Witt, B. Schulz

    1982Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme5 citations

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43. (Pro)Insulin Biosynthesis and Secretion of Islets Prepared from Human Pancreas Biopsies

    H. Jahr, Dietmar Lorenz, W. Besch, H. Zuhlke +3 more

    1980Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme5 citations

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44. Influence of polyethylene glycol (PEG) extraction on the C-peptide determination in sera from insulin-dependent diabetic patients with circulating insulin antibodies.

    W. Besch, H. Keilacker, K. Kohnert, M. Ziegler

    2009Experimental and clinical endocrinology4 citations

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45. Mathematical Modelling of Competitive Labelled-Ligand Assay Systems. Theoretical Re-Evaluation of Optimum Assay Conditions and Precision Data for Some Experimentally Established Radioimmunoassay Systems

    H. Keilacker, W. Besch, K. P. Woltanski, J. Diaz-Alonso +2 more

    1991European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies4 citations Open access

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46. Early Enhanced Beta Cell Replication in Normoglycaemic Wistar Rats in Response to a Subdiabetogenic Dose of Streptozotocin

    B. Ziegler, S. Lucke, W. Besch, H. Hahn

    1989Experimental and clinical endocrinology4 citations

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47. Effect of temporary IL-2 receptor MAB therapy on islet allograft in autoimmune diabetes.

    H. Hahn, B. Kuttler, S. Lucke, A. Dunger +3 more

    1989Transplantation Proceedings4 citations

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48. Diabetogenic Effects of N-Nitrosomethylurea in Rats

    Christel Voss, I. Herrmann, K. Hartmann, H. Zuhlke +2 more

    1988Experimental and clinical endocrinology4 citations

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49. Polyacrylamide gel electrophoretic preparation of labeled and non-labeled peptides for radioimmunoassay.

    W. Besch, K. Woltanski, H. Keilacker, K. Kohnert

    1986Biomedica biochimica acta4 citations

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50. Generation and partial characterization of monoclonal antibodies reactive with islet cell antigens.

    S. Witt, Brigitte Ziegler, B. Waterstradt, W. Besch +2 more

    2009Experimental and clinical endocrinology3 citations

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