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A. Batta · SciRah

Researcher profile · Semantic Scholar

A. Batta

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A. Batta — researcher profile on SciRah

h-index: 42
Works: 178
Citations: 7,501

Most-cited papers

Human cholesterol 7alpha-hydroxylase (CYP7A1) deficiency has a hypercholesterolemic phenotype.
C. Pullinger, C. Eng, G. Salen, S. Shefer +7 more
2002Journal of Clinical Investigation438 citations Open access
Semantic Scholar
Complex inheritance of familial hypercholanemia with associated mutations in TJP2 and BAAT
V. Carlton, Baruch Z. Harris, E. Puffenberger, A. Batta +8 more
2003Nature Genetics297 citations
Semantic Scholar
Biliary cholesterol excretion: a novel mechanism that regulates dietary cholesterol absorption.
E. Sehayek, Jennie G. Ono, S. Shefer, Lien B. Nguyen +6 more
1998Proceedings of the National Academy of Sciences of the United States of America185 citations Open access
Semantic Scholar
7-Dehydrocholesterol-dependent proteolysis of HMG-CoA reductase suppresses sterol biosynthesis in a mouse model of Smith-Lemli-Opitz/RSH syndrome.
B. Fitzky, F. F. Moebius, H. Asaoka, H. Waage-Baudet +16 more
2001Journal of Clinical Investigation166 citations Open access
Semantic Scholar
Markedly inhibited 7-dehydrocholesterol-delta 7-reductase activity in liver microsomes from Smith-Lemli-Opitz homozygotes.
S. Shefer, G. Salen, A. Batta, A. Honda +5 more
1995Journal of Clinical Investigation156 citations Open access
Semantic Scholar
Stigmasterol reduces plasma cholesterol levels and inhibits hepatic synthesis and intestinal absorption in the rat.
A. Batta, Guo-Rong Xu, A. Honda, T. Miyazaki +1 more
2006Metabolism: Clinical and Experimental153 citations
Semantic Scholar
A mouse model of sitosterolemia: absence of Abcg8/sterolin-2 results in failure to secrete biliary cholesterol
E. Klett, K. Lu, A. Kosters, E. Vink +13 more
2004BMC Medicine147 citations Open access
Semantic Scholar
Human cholesterol 7a-hydroxylase (CYP7A1) deficiency has a hypercholesterolemic phenotype
C. Pullinger, C. Eng, G. Salen, S. Shefer +7 more
2018137 citations Open access
Semantic Scholar
Correlation of severity and outcome with plasma sterol levels in variants of the Smith-Lemli-Opitz syndrome.
G. Tint, G. Salen, A. Batta, S. Shefer +10 more
1995Jornal de Pediatria134 citations
Semantic Scholar
Markedly increased tissue concentrations of 7-dehydrocholesterol combined with low levels of cholesterol are characteristic of the Smith-Lemli-Opitz syndrome.
G. Tint, M. Seller, R. Hughes-Benzie, A. Batta +5 more
1995Journal of Lipid Research131 citations
Semantic Scholar
Identification of an endogenous ligand that activates pregnane X receptor-mediated sterol clearance
I. Dussault, H. Yoo, Min Lin, Eric Wang +5 more
2003Proceedings of the National Academy of Sciences of the United States of America126 citations Open access
Semantic Scholar
Hypercholesterolemia and changes in lipid and bile acid metabolism in male and female cyp7A1-deficient mice Published, JLR Papers in Press, February 16, 2003. DOI 10.1194/jlr.M200489-JLR200
S. Erickson, S. R. Lear, S. Deane, S. Dubrac +13 more
2003Journal of Lipid Research118 citations Open access
Semantic Scholar
Identification of 8-dehydrocholesterol (cholesta-5,8-dien-3 beta-ol) in patients with Smith-Lemli-Opitz syndrome.
A. Batta, G. Tint, S. Shefer, Dianne N. Abuelo +1 more
1995Journal of Lipid Research89 citations
Semantic Scholar
Side Chain Hydroxylations in Bile Acid Biosynthesis Catalyzed by CYP3A Are Markedly Up-regulated in Cyp27−/− Mice but Not in Cerebrotendinous Xanthomatosis*
A. Honda, G. Salen, Y. Matsuzaki, A. Batta +6 more
2001Journal of Biological Chemistry86 citations Open access
Semantic Scholar
Substrate specificities of rat oatp1 and ntcp: implications for hepatic organic anion uptake.
S. Hata, Pi-Jun Wang, Nicole Eftychiou, M. Ananthanarayanan +4 more
2003American Journal of Physiology - Gastrointestinal and Liver Physiology83 citations
Semantic Scholar
Defective conversion of 7-dehydrocholesterol to cholesterol in cultured skin fibroblasts from Smith-Lemli-Opitz syndrome homozygotes.
Akira Honda, G. Tint, G. Salen, A. Batta +2 more
1995Journal of Lipid Research79 citations
Semantic Scholar
Abnormal cholesterol biosynthesis in the Smith-Lemli-Opitz syndrome.
G. Salen, G. Tint, Guo-Rong Xu, A. Batta +2 more
1995The Italian journal of gastroenterology79 citations
Semantic Scholar
Simultaneous quantitation of fatty acids, sterols and bile acids in human stool by capillary gas-liquid chromatography.
A. Batta, G. Salen, P. Batta, G. Tint +2 more
2002Journal of chromatography. B, Analytical technologies in the biomedical and life sciences74 citations
Semantic Scholar
Prenatal detection of the cholesterol biosynthetic defect in the Smith-Lemli-Opitz syndrome by the analysis of amniotic fluid sterols.
D. Abuelo, G. Tint, R. Kelley, A. Batta +2 more
1995American journal of medical genetics72 citations
Semantic Scholar
Differences in hepatic levels of intermediates in bile acid biosynthesis between Cyp27(-/-) mice and CTX.
A. Honda, G. Salen, Y. Matsuzaki, A. Batta +6 more
2001Journal of Lipid Research69 citations
Semantic Scholar
Ileal bile acid transport regulates bile acid pool, synthesis, and plasma cholesterol levels differently in cholesterol-fed rats and rabbits.
Guo-Rong Xu, B. Shneider, S. Shefer, L. Nguyen +10 more
2000Journal of Lipid Research65 citations
Semantic Scholar
Inhibition of ileal bile acid transport lowers plasma cholesterol levels by inactivating hepatic farnesoid X receptor and stimulating cholesterol 7 alpha-hydroxylase.
Hai Li, Guo-Rong Xu, Q. Shang, Lu-xing Pan +6 more
2004Metabolism: Clinical and Experimental64 citations
Semantic Scholar
Role of CYP27A in cholesterol and bile acid metabolism Published, JLR Papers in Press, November 1, 2004. DOI 10.1194/jlr.M400219-JLR200
S. Dubrac, S. R. Lear, M. Ananthanarayanan, N. Balasubramaniyan +11 more
2005Journal of Lipid Research59 citations Open access
Semantic Scholar
Cholesterol and oxygenated cholesterol concentrations are markedly elevated in peripheral tissue but not in brain from mice with the Niemann–Pick type C phenotype
G. Tint, P. Pentchev, Guo-Rong Xu, A. Batta +3 more
1998Journal of Inherited Metabolic Disease52 citations
Semantic Scholar
Comparative effects of lovastatin and chenodeoxycholic acid on plasma cholestanol levels and abnormal bile acid metabolism in cerebrotendinous xanthomatosis.
G. Salen, A. Batta, G. Tint, S. Shefer
1994Metabolism: Clinical and Experimental52 citations
Semantic Scholar
Comparison of Changes in Lipid Profile after Bilio-intestinal Bypass and Gastric Banding in Patients with Morbid Obesity
S. Corradini, A. Eramo, C. Lubrano, G. Spera +9 more
2005Obesity Surgery51 citations
Semantic Scholar
Bile acid synthesis in the Smith-Lemli-Opitz syndrome: effects of dehydrocholesterols on cholesterol 7alpha-hydroxylase and 27-hydroxylase activities in rat liver.
A. Honda, G. Salen, S. Shefer, A. Batta +6 more
1999Journal of Lipid Research49 citations
Semantic Scholar
Hyodeoxycholic acid efficiently suppresses atherosclerosis formation and plasma cholesterol levels in mice.
E. Sehayek, Jennie G. Ono, Elizabeth M. Duncan, A. Batta +6 more
2001Journal of Lipid Research42 citations Open access
Semantic Scholar
Loci on chromosomes 14 and 2, distinct from ABCG5/ABCG8, regulate plasma plant sterol levels in a C57BL/6J × CASA/Rk intercross
E. Sehayek, Elizabeth M. Duncan, D. Lütjohann, K. von Bergmann +4 more
2002Proceedings of the National Academy of Sciences of the United States of America41 citations Open access
Semantic Scholar
Down-regulation of cholesterol biosynthesis in sitosterolemia: diminished activities of acetoacetyl-CoA thiolase, 3-hydroxy-3-methylglutaryl-CoA synthase, reductase, squalene synthase, and 7-dehydrocholesterol delta7-reductase in liver and mononuclear leukocytes.
Akira Honda, G. Salen, L. Nguyen, G. Tint +2 more
1998Journal of Lipid Research41 citations Open access
Semantic Scholar
Regulation of the Farnesoid X Receptor (FXR) by Bile Acid Flux in Rabbits*
Guo-Rong Xu, Lu-xing Pan, Hai Li, B. M. Forman +13 more
2002Journal of Biological Chemistry40 citations Open access
Semantic Scholar
Fetal Smith‐Lemli‐Opitz syndrome can be detected accurately and reliably by measuring amniotic fluid dehydrocholesterols
G. Tint, D. Abuelo, M. Till, M. Cordier +8 more
1998Prenatal Diagnosis40 citations
Semantic Scholar
Relationship between biliary and serum bile acids and response to ursodeoxycholic acid in patients with primary biliary cirrhosis
K. Lindor, M. A. Lacerda, R. Jorgensen, C. K. DeSotel +5 more
1998American Journal of Gastroenterology40 citations
Semantic Scholar
Comparative regulation of hepatic sterol 27-hydroxylase and cholesterol 7alpha-hydroxylase activities in the rat, guinea pig, and rabbit: effects of cholesterol and bile acids.
Lien B. Nguyen, Guo-Rong Xu, S. Shefer, G. Tint +2 more
1999Metabolism: Clinical and Experimental39 citations
Semantic Scholar
Gas chromatography of bile acids.
A. Batta, G. Salen
1999Journal of Chromatography B: Biomedical Sciences and Applications39 citations
Semantic Scholar
Regulation of rat hepatic 3beta-hydroxysterol delta7-reductase: substrate specificity, competitive and non-competitive inhibition, and phosphorylation/dephosphorylation.
S. Shefer, G. Salen, Akira Honda, A. Batta +4 more
1998Journal of Lipid Research37 citations
Semantic Scholar
Relationship between abnormal cholesterol synthesis and retarded learning in rats.
Guo-Rong Xu, Richard J. Servatius, S. Shefer, G. Tint +3 more
1998Metabolism: Clinical and Experimental36 citations
Semantic Scholar
Hepatic cholesterol and bile acid synthesis, low-density lipoprotein receptor function, and plasma and fecal sterol levels in mice: effects of apolipoprotein E deficiency and probucol or phytosterol treatment.
M. Moghadasian, L. Nguyen, S. Shefer, G. Salen +2 more
2001Metabolism: Clinical and Experimental34 citations
Semantic Scholar
Effect of high plant sterol-enriched diet and cholesterol absorption inhibitor, SCH 58235, on plant sterol absorption and plasma concentrations in hypercholesterolemic wild-type Kyoto rats.
A. Batta, Guo-Rong Xu, J. Bollineni, S. Shefer +1 more
2005Metabolism: Clinical and Experimental29 citations
Semantic Scholar
The Smith-Lemli-Opitz syndrome: a potentially fatal birth defect caused by a block in the last enzymatic step in cholesterol biosynthesis.
G. Tint, A. Batta, Guo-Rong Xu, S. Shefer +4 more
1997Sub-cellular biochemistry29 citations
Semantic Scholar
Measurement of 3 beta-hydroxysteroid delta 7-reductase activity in cultured skin fibroblasts utilizing ergosterol as a substrate: a new method for the diagnosis of the Smith-Lemli-Opitz syndrome.
M. Honda, G. Tint, Akira Honda, A. Batta +3 more
1996Journal of Lipid Research28 citations
Semantic Scholar
Identification of 19-nor-5,7,9(10)-cholestatrien-3 beta-ol in patients with Smith-Lemli-Opitz syndrome.
A. Batta, G. Salen, G. Tint, S. Shefer
1995Journal of Lipid Research28 citations
Semantic Scholar
Hydrophilic 7 beta-hydroxy bile acids, lovastatin, and cholestyramine are ineffective in the treatment of cerebrotendinous xanthomatosis.
A. Batta, G. Salen, G. Tint
2004Metabolism: Clinical and Experimental27 citations
Semantic Scholar
Competitive inhibition of hepatic sterol 27-hydroxylase by sitosterol: decreased activity in sitosterolemia.
L. Nguyen, S. Shefer, G. Salen, S. Tint +1 more
1998Proceedings of the Association of American Physicians27 citations
Semantic Scholar
Sterol concentrations in cultured Smith-Lemli-Opitz syndrome skin fibroblasts: diagnosis of a biochemically atypical case of the syndrome.
Akira Honda, G. Tint, G. Salen, R. Kelley +4 more
1997American journal of medical genetics27 citations
Semantic Scholar
Abnormal hepatic sinusoidal bile acid transport in an Amish kindred is not linked to FIC1 and is improved by ursodiol.
D. Morton, G. Salen, A. Batta, S. Shefer +6 more
2000Gastroenterology26 citations Open access
Semantic Scholar
Screening for abnormal cholesterol biosynthesis in the Smith-Lemli-Opitz syndrome: rapid determination of plasma 7-dehydrocholesterol by ultraviolet spectrometry.
Akira Honda, A. Batta, G. Salen, G. Tint +2 more
1997American journal of medical genetics24 citations
Semantic Scholar
Increasing hepatic cholesterol 7α‐hydroxylase reduces plasma cholesterol concentrations in normocholesterolemic and hypercholesterolemic rabbits
Guo-Rong Xu, G. Salen, S. Shefer, Gene C. Ness +8 more
1996Hepatology24 citations Open access
Semantic Scholar
Regulation of bile acid synthesis by deoxycholic acid in the rat: Different effects on cholesterol 7α-hydroxylase and sterol 27-hydroxylase
S. Shefer, B. Kren, G. Salen, C. Steer +4 more
199524 citations
Semantic Scholar
Calcium affinity for biliary lipid aggregates in model biles: complementary importance of bile salts and lecithin.
J. Donovan, M. R. Leonard, A. Batta, M. Carey
1994Gastroenterology23 citations Open access
Semantic Scholar

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G. Salen×49
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G. Salen — researcher profile on SciRah
S. Shefer×38
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S. Shefer — researcher profile on SciRah
G. Tint×29
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G. Tint — researcher profile on SciRah
Guo-Rong Xu×12
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Guo-Rong Xu — researcher profile on SciRah

×8

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S. Erickson — researcher profile on SciRah

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Akira Honda — researcher profile on SciRah

Thomas S. Chen×6

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Thomas S. Chen — researcher profile on SciRah

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A. Honda — researcher profile on SciRah

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L. Nguyen — researcher profile on SciRah

J. Bollineni×5

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J. Bollineni — researcher profile on SciRah

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E. Sehayek — researcher profile on SciRah

Lien B. Nguyen×4

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Lien B. Nguyen — researcher profile on SciRah