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T. Haselhorst · SciRah

Researcher profile · Semantic Scholar

T. Haselhorst

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T. Haselhorst — researcher profile on SciRah

h-index: 29
Works: 98
Citations: 2,489

Most-cited papers

Sialic acid dependence in rotavirus host cell invasion.
T. Haselhorst, F. Fleming, J. C. Dyason, R. D. Hartnell +7 more
2009Nature Chemical Biology165 citations
Semantic Scholar
Liposomal doxorubicin as targeted delivery platform: Current trends in surface functionalization.
Vivek Makwana, Jasmine D. Karanjia, T. Haselhorst, S. Anoopkumar-Dukie +1 more
2020International journal of pharmaceutics120 citations Open access
Semantic Scholar
Unravelling the Role of O-glycans in Influenza A Virus Infection
Juliane V. Mayr, Kam Lau, J. Lai, I. Gagarinov +6 more
2018Scientific Reports118 citations Open access
Semantic Scholar
Ferrets exclusively synthesize Neu5Ac and express naturally humanized influenza A virus receptors
Preston S. K. Ng, Raphael Böhm, L. Hartley-Tassell, J. Steen +11 more
2014Nature Communications106 citations Open access
Semantic Scholar
Structure and function of nucleotide sugar transporters: Current progress
Barbara Hadley, A. Maggioni, A. Ashikov, Christopher J. Day +2 more
2014Computational and Structural Biotechnology Journal106 citations Open access
Semantic Scholar
Nucleotide Sugar Transporter SLC35 Family Structure and Function
Barbara Hadley, Thomas Litfin, Christopher J. Day, T. Haselhorst +2 more
2019Computational and Structural Biotechnology Journal96 citations Open access
Semantic Scholar
Revisiting the role of histo-blood group antigens in rotavirus host-cell invasion
Raphael Böhm, F. Fleming, A. Maggioni, V. Dang +4 more
2015Nature Communications90 citations Open access
Semantic Scholar
Molecular recognition of sialyl Lewis(x) and related saccharides by two lectins.
T. Haselhorst, T. Weimar, T. Peters
2001Journal of the American Chemical Society90 citations
Semantic Scholar
Carbocycles related to oseltamivir as influenza virus group-1-specific neuraminidase inhibitors. Binding to N1 enzymes in the context of virus-like particles.
S. Mohan, S. McAtamney, T. Haselhorst, M. von Itzstein +1 more
2010Journal of Medicinal Chemistry87 citations Open access
Semantic Scholar
CD52 glycan binds the proinflammatory B box of HMGB1 to engage the Siglec-10 receptor and suppress human T cell function
E. Bandala-Sanchez, N. Bediaga, E. Goddard-Borger, K. Ngui +11 more
2018Proceedings of the National Academy of Sciences of the United States of America81 citations Open access
Semantic Scholar
All major cholesterol-dependent cytolysins use glycans as cellular receptors
L. Shewell, Christopher J. Day, F. Jen, T. Haselhorst +16 more
2020Science Advances65 citations Open access
Semantic Scholar
STD NMR spectroscopy and molecular modeling investigation of the binding of N-acetylneuraminic acid derivatives to rhesus rotavirus VP8* core.
T. Haselhorst, H. Blanchard, M. Frank, Mark J Kraschnefski +7 more
2007Glycobiology61 citations Open access
Semantic Scholar
Molecular Cloning of the Leishmania major UDP-glucose Pyrophosphorylase, Functional Characterization, and Ligand Binding Analyses Using NMR Spectroscopy*
Anne-Christin Lamerz, T. Haselhorst, A. Bergfeld, M. von Itzstein +1 more
2006Journal of Biological Chemistry60 citations Open access
Semantic Scholar
Multidisciplinary Approaches Identify Compounds that Bind to Human ACE2 or SARS-CoV-2 Spike Protein as Candidates to Block SARS-CoV-2–ACE2 Receptor Interactions
Christopher J. Day, B. Bailly, P. Guillon, Larissa Dirr +6 more
2021mBio57 citations Open access
Semantic Scholar
Avian influenza H5-containing virus-like particles (VLPs): host-cell receptor specificity by STD NMR spectroscopy.
T. Haselhorst, Jean-Michel Garcia, Tasneem Islam, J. Lai +4 more
2008Angewandte Chemie51 citations
Semantic Scholar
Relative Roles of GM1 Ganglioside, N-Acylneuraminic Acids, and α2β1 Integrin in Mediating Rotavirus Infection
F. Fleming, Raphael Böhm, V. Dang, G. Holloway +7 more
2014Journal of Virology49 citations Open access
Semantic Scholar
Production of active human glucocerebrosidase in seeds of Arabidopsis thaliana complex-glycan-deficient (cgl) plants.
Xu He, J. Galpin, M. Tropak, D. Mahuran +9 more
2012Glycobiology46 citations Open access
Semantic Scholar
Carbohydrate Recognition Specificity of Trans-sialidase Lectin Domain from Trypanosoma congolense
Mario Waespy, Thaddeus T. Gbem, Leroy Elenschneider, André-Philippe Jeck +6 more
2015PLoS Neglected Tropical Diseases43 citations Open access
Semantic Scholar
Saturation transfer difference NMR spectroscopy as a technique to investigate protein-carbohydrate interactions in solution.
T. Haselhorst, Anne-Christin Lamerz, M. von Itzstein
2009Methods in molecular biology43 citations
Semantic Scholar
Structure-guided discovery of potent and dual-acting human parainfluenza virus haemagglutinin–neuraminidase inhibitors
P. Guillon, Larissa Dirr, I. El-Deeb, Moritz Winger +4 more
2014Nature Communications41 citations Open access
Semantic Scholar
Leishmania UDP-sugar Pyrophosphorylase
S. Damerow, Anne-Christin Lamerz, T. Haselhorst, J. Führing +3 more
2009Journal of Biological Chemistry39 citations Open access
Semantic Scholar
Recognition of the GM3 ganglioside glycan by Rhesus rotavirus particles.
T. Haselhorst, T. Fiebig, J. C. Dyason, F. Fleming +3 more
2011Angewandte Chemie38 citations
Semantic Scholar
Functional and structural characterization of a heparanase.
Liza Bohlmann, Gregory D. Tredwell, Xing Yu, Chih-Wei Chang +8 more
2015Nature Chemical Biology37 citations
Semantic Scholar
C-4 modified sialosides enhance binding to Siglec-2 (CD22): towards potent Siglec inhibitors for immunoglycotherapy.
S. Kelm, P. Madge, Tasneem Islam, R. Bennett +4 more
2013Angewandte Chemie36 citations
Semantic Scholar
The role of sialic acid-binding immunoglobulin-like-lectin-1 (siglec-1) in immunology and infectious disease
Shane Prenzler, S. Rudrawar, Mario Waespy, S. Kelm +2 more
2021International Reviews of Immunology31 citations Open access
Semantic Scholar
A secondary sialic acid binding site on influenza virus neuraminidase: fact or fiction?
J. Lai, Jean-Michel Garcia, J. C. Dyason, Raphael Böhm +6 more
2012Angewandte Chemie31 citations
Semantic Scholar
Proteolytic Release of the Intramolecular Chaperone Domain Confers Processivity to Endosialidase F*
David Schwarzer, Katharina Stummeyer, T. Haselhorst, Friedrich Freiberger +6 more
2009Journal of Biological Chemistry31 citations Open access
Semantic Scholar
Influence of an ER-retention signal on the N-glycosylation of recombinant human α-l-iduronidase generated in seeds of Arabidopsis
Xu He, T. Haselhorst, M. von Itzstein, D. Kolarich +2 more
2012Plant Molecular Biology30 citations
Semantic Scholar
NMR spectroscopic and molecular modeling investigations of the trans-sialidase from Trypanosoma cruzi.
T. Haselhorst, Jennifer C. Wilson, Angela Liakatos, M. Kiefel +2 more
2004Glycobiology29 citations Open access
Semantic Scholar
Biochemical and Biophysical Characterization of the Sialyl-/Hexosyltransferase Synthesizing the Meningococcal Serogroup W135 Heteropolysaccharide Capsule*
A. Romanow, T. Haselhorst, Katharina Stummeyer, H. Claus +5 more
2013Journal of Biological Chemistry28 citations Open access
Semantic Scholar
The dCache Chemoreceptor TlpA of Helicobacter pylori Binds Multiple Attractant and Antagonistic Ligands via Distinct Sites
K. S. Johnson, Bassam A. Elgamoudi, F. Jen, Christopher J. Day +6 more
2021mBio24 citations Open access
Semantic Scholar
Investigation of the binding and cleavage characteristics of N1 neuraminidases from avian, seasonal, and pandemic influenza viruses using saturation transfer difference nuclear magnetic resonance
Jean-Michel Garcia, J. Lai, T. Haselhorst, Ka-Tim Choy +4 more
2013Influenza and Other Respiratory Viruses24 citations Open access
Semantic Scholar
Production of α-L-iduronidase in maize for the potential treatment of a human lysosomal storage disease
Xu He, T. Haselhorst, M. von Itzstein, D. Kolarich +6 more
2012Nature Communications24 citations Open access
Semantic Scholar
Repurposed Drugs That Block the Gonococcus-Complement Receptor 3 Interaction Can Prevent and Cure Gonococcal Infection of Primary Human Cervical Epithelial Cells
J. Poole, Christopher J. Day, T. Haselhorst, F. Jen +3 more
2020mBio23 citations Open access
Semantic Scholar
Neisseria gonorrhoeae Becomes Susceptible to Polymyxin B and Colistin in the Presence of PBT2.
F. Jen, A. Everest-Dass, I. El-Deeb, Sanjesh Singh +4 more
2019ACS Infectious Diseases23 citations Open access
Semantic Scholar
Enhancing Vaccine Efficacy by Engineering a Complex Synthetic Peptide To Become a Super Immunogen
Therése Nordström, Manisha Pandey, Ainslie Calcutt, J. Powell +8 more
2017Journal of Immunology23 citations
Semantic Scholar
Saturation transfer difference (STD) 1H‐NMR experiments and in silico docking experiments to probe the binding of N‐acetylneuraminic acid and derivatives to Vibrio cholerae sialidase
T. Haselhorst, Jennifer C. Wilson, R. Thomson, S. McAtamney +3 more
2004Proteins: Structure, Function, and Bioinformatics23 citations
Semantic Scholar
Exploring human parainfluenza virus type-1 hemagglutinin-neuraminidase as a target for inhibitor discovery.
I. El-Deeb, P. Guillon, Moritz Winger, Tanguy Eveno +3 more
2014Journal of Medicinal Chemistry22 citations Open access
Semantic Scholar
Direct detection of ligand binding to Sepharose-immobilised protein using saturation transfer double difference (STDD) NMR spectroscopy.
T. Haselhorst, Anja K. Münster-Kühnel, M. Oschlies, J. Tiralongo +2 more
2007Biochemical and Biophysical Research Communications - BBRC22 citations
Semantic Scholar
Host glycocalyx captures HIV proximal to the cell surface via oligomannose-GlcNAc glycan-glycan interactions to support viral entry.
B. Spillings, Christopher J. Day, Albert Garcia-Minambres, A. Aggarwal +7 more
2022Cell Reports21 citations Open access
Semantic Scholar
Characterization and downstream mannose phosphorylation of human recombinant α-L-iduronidase produced in Arabidopsis complex glycan-deficient (cgl) seeds
Xu He, Owen M. Pierce, T. Haselhorst, M. von Itzstein +7 more
2013Plant Biotechnology Journal19 citations Open access
Semantic Scholar
Glycobiology of Human Fungal Pathogens: New Avenues for Drug Development
Danielle J. Lee, H. O'Donnell, F. Routier, J. Tiralongo +1 more
2019Cells17 citations Open access
Semantic Scholar
The essential malaria protein PfCyRPA targets glycans to invade erythrocytes.
Christopher J. Day, P. Favuzza, Sabrina Bielfeld, T. Haselhorst +17 more
2024Cell Reports16 citations Open access
Semantic Scholar
The Nontypeable Haemophilus influenzae Major Adhesin Hia Is a Dual-Function Lectin That Binds to Human-Specific Respiratory Tract Sialic Acid Glycan Receptors
John M. Atack, Christopher J. Day, J. Poole, K. Brockman +6 more
2020bioRxiv16 citations Open access
Semantic Scholar
Structural characterisation of high affinity Siglec-2 (CD22) ligands in complex with whole Burkitt’s lymphoma (BL) Daudi cells by NMR spectroscopy
P. Madge, A. Maggioni, Mauro Pascolutti, M. Amin +6 more
2016Scientific Reports16 citations Open access
Semantic Scholar
A C-terminal phosphatase module conserved in vertebrate CMP-sialic acid synthetases provides a tetramerization interface for the physiologically active enzyme.
M. Oschlies, A. Dickmanns, T. Haselhorst, W. Schaper +7 more
2009Journal of Molecular Biology16 citations
Semantic Scholar
Probing a CMP-Kdn synthetase by 1H, 31P, and STD NMR spectroscopy.
T. Haselhorst, Anja K. Münster-Kühnel, A. Stolz, M. Oschlies +4 more
2005Biochemical and Biophysical Research Communications - BBRC16 citations
Semantic Scholar
Development of a broad-spectrum therapeutic Fc-nanobody for human noroviruses
G. Hansman, Gargi Kher, Anna Svirina, J. Tame +6 more
2024Journal of Virology15 citations
Semantic Scholar
Ucl fimbriae regulation and glycan receptor specificity contribute to gut colonisation by extra-intestinal pathogenic Escherichia coli
Steven J. Hancock, Alvin W. Lo, T. Ve, Christopher J. Day +17 more
2022PLoS Pathogens15 citations Open access
Semantic Scholar
Conformational analysis of a Chlamydia-specific disaccharide α-Kdo-(2→8)-α-Kdo-(2→O)-allyl in aqueous solution and bound to a monoclonal antibody: Observation of intermolecular transfer NOEs
T. Sokolowski, T. Haselhorst, K. Scheffler, R. Weisemann +4 more
199815 citations
Semantic Scholar

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M. von Itzstein×35
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Christopher J. Day×11
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M. Jennings×8
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J. Tiralongo×8
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J. C. Dyason — researcher profile on SciRah

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F. Fleming — researcher profile on SciRah

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