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J. Valjakka · SciRah

Researcher profile · Semantic Scholar

J. Valjakka

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J. Valjakka — researcher profile on SciRah

h-index: 20
Works: 52
Citations: 1,559

Most-cited papers

Biochemical Characterization of CA IX, One of the Most Active Carbonic Anhydrase Isozymes*
M. Hilvo, L. Baranauskienė, A. Salzano, A. Scaloni +15 more
2008Journal of Biological Chemistry287 citations Open access
Semantic Scholar
Zinc coordination spheres in protein structures.
Mikko Laitaoja, J. Valjakka, J. Jänis
2013Inorganic Chemistry240 citations
Semantic Scholar
Molecular dynamics studies on the thermostability of family 11 xylanases.
M. Purmonen, J. Valjakka, K. Takkinen, T. Laitinen +1 more
2007Protein engineering, design & selection : PEDS124 citations Open access
Semantic Scholar
Rhizavidin from Rhizobium etli: the first natural dimer in the avidin protein family.
Satu H. Helppolainen, Kirsi Nurminen, Juha A. E. Määttä, Katrin K. Halling +11 more
2007Biochemical Journal95 citations Open access
Semantic Scholar
Activities of Angiotensin-Converting Enzymes ACE1 and ACE2 and Inhibition by Bioactive Peptides in Porcine Ocular Tissues
S. Luhtala, Anu Vaajanen, O. Oksala, J. Valjakka +1 more
2009Journal of Ocular Pharmacology and Therapeutics75 citations
Semantic Scholar
Angiotensin(1-7) and ACE2, “The Hot Spots” of Renin-Angiotensin System, Detected in the Human Aqueous Humor
M. Holappa, J. Valjakka, Anu Vaajanen
2015Open Ophthalmology Journal69 citations Open access
Semantic Scholar
DNA-Binding and -Bending Activities of SAP30L and SAP30 Are Mediated by a Zinc-Dependent Module and Monophosphoinositides
K. Viiri, J. Jänis, T. Siggers, T. Heinonen +4 more
2008Molecular and Cellular Biology58 citations Open access
Semantic Scholar
The challenges of using NAD+-dependent formate dehydrogenases for CO2 conversion
Saadet Alpdağtaş, O. Turunen, J. Valjakka, Barış Binay
2021Critical Reviews in Biotechnology55 citations
Semantic Scholar
Crystal Structure of an in Vitro Affinity- and Specificity-matured Anti-testosterone Fab in Complex with Testosterone
J. Valjakka, A. Hemminki, S. Niemi, H. Söderlund +2 more
2002Journal of Biological Chemistry49 citations Open access
Semantic Scholar
Engineered formate dehydrogenase from Chaetomium thermophilum, a promising enzymatic solution for biotechnical CO2 fixation
M. M. Çakar, Jouni Ruupunen, J. Mangas-Sánchez, W. Birmingham +5 more
2020Biotechnology Letters45 citations
Semantic Scholar
Chaetomium thermophilum formate dehydrogenase has high activity in the reduction of hydrogen carbonate (HCO3 −) to formate
Aşkın Sevinç Aslan, J. Valjakka, Jouni Ruupunen, D. Yıldırım +3 more
2017Protein engineering, design & selection : PEDS37 citations Open access
Semantic Scholar
Characterization of Non-Specific Cytotoxic Cell Receptor Protein 1: A New Member of the Lectin-Type Subfamily of F-Box Proteins
H. Kallio, M. Tolvanen, J. Jänis, Pei-wen Pan +9 more
2011PLoS ONE36 citations Open access
Semantic Scholar
Analysis of a shortened form of human carbonic anhydrase VII expressed in vitro compared to the full-length enzyme.
F. Bootorabi, J. Jänis, Elona Smith, A. Waheed +7 more
2010Biochimie36 citations
Semantic Scholar
Structure-function analysis indicates that sumoylation modulates DNA-binding activity of STAT1
J. Grönholm, Sari Vanhatupa, D. Ungureanu, J. Väliaho +3 more
2012BMC Biochemistry33 citations Open access
Semantic Scholar
Functional effects of active site mutations in NAD+-dependent formate dehydrogenases on transformation of hydrogen carbonate to formate.
U. Pala, B. Yelmazer, Meltem Çorbacıoğlu, Jouni Ruupunen +3 more
2018Protein engineering, design & selection : PEDS28 citations Open access
Semantic Scholar
Structure-based stability engineering of the mouse IgG1 Fab fragment by modifying constant domains.
T. Teerinen, J. Valjakka, J. Rouvinen, K. Takkinen
2006Journal of Molecular Biology28 citations
Semantic Scholar
Acetaldehyde-derived modifications on cytosolic human carbonic anhydrases
F. Bootorabi, J. Jänis, V. Hytönen, J. Valjakka +5 more
2011Journal of Enzyme Inhibition and Medicinal Chemistry21 citations Open access
Semantic Scholar
Direction-dependent initial-state relaxation in oxygen K x-ray emission.
J. Valjakka, J. Utriainen, T. Åberg, J. Tulkki
1985Physical Review B (Condensed Matter)21 citations
Semantic Scholar
Modification of carbonic anhydrase II with acetaldehyde, the first metabolite of ethanol, leads to decreased enzyme activity
F. Bootorabi, J. Jänis, J. Valjakka, Sari Isoniemi +7 more
2008BMC Biochemistry20 citations Open access
Semantic Scholar
Unreliability of the Chou-Fasman parameters in predicting protein secondary structure.
J. Kyngäs, J. Valjakka
1998Protein Engineering20 citations
Semantic Scholar
Cloning and expression heterologous alanine dehydrogenase genes: Investigation of reductive amination potential of L-alanine dehydrogenases for green synthesis of alanine derivatives
Ğarip Demir, J. Valjakka, Ossi Turunen, Fatih Aktaş +1 more
2024Heliyon17 citations Open access
Semantic Scholar
Production of L-xylose from L-xylulose using Escherichia coli L-fucose isomerase.
Anne Usvalampi, O. Turunen, J. Valjakka, O. Pastinen +2 more
2012Enzyme and Microbial Technology17 citations
Semantic Scholar
Structural Insights into Steroid Hormone Binding
J. Valjakka, Kristiina Takkinenz, T. Teerinen, H. Söderlund +1 more
2002Journal of Biological Chemistry17 citations Open access
Semantic Scholar
Effect of Metal Ions on the Activity of Ten NAD-Dependent Formate Dehydrogenases
H. Bulut, J. Valjakka, Busra Yuksel, Berin Yılmazer +2 more
2020The Protein Journal16 citations
Semantic Scholar
Application of reductive amination by heterologously expressed Thermomicrobium roseumL-alanine dehydrogenase to synthesize L-alanine derivatives.
H. Bulut, J. Valjakka, O. Turunen, Berin Yılmazer +3 more
2023Enzyme and Microbial Technology15 citations Open access
Semantic Scholar
The talin-integrin interface under mechanical stress.
S. Kukkurainen, Juha A. E. Määttä, John Saeger, J. Valjakka +2 more
2014Molecular Biosystems12 citations
Semantic Scholar
EVOLUTIONARY NEURAL NETWORKS IN QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIPS OF DIHYDROFOLATE REDUCTASE INHIBITORS
Jari Kyngäs, J. Valjakka
199612 citations
Semantic Scholar
Novel Thermus thermophilus L-alanine dehydrogenase mutants: Synthesis of L-alanine derivatives with reductive amination.
Ğarip Demir, J. Valjakka, Ossi Turunen, Deniz Yildirim +1 more
2025International Journal of Biological Macromolecules11 citations Open access
Semantic Scholar
Redox‐dependent disulfide bond formation in SAP30L corepressor protein: Implications for structure and function
Mikko Laitaoja, H. Tossavainen, T. Pihlajamaa, J. Valjakka +4 more
2016Protein Science10 citations Open access
Semantic Scholar
Structure of 20K endoglucanase from Melanocarpus albomyces at 1.8 A resolution.
J. Valjakka, J. Rouvinen
2003Acta Crystallographica Section D: Biological Crystallography10 citations
Semantic Scholar
Analysis of the binding energies of testosterone, 5α‐dihydrotestosterone, androstenedione and dehydroepiandrosterone sulfate with an antitestosterone antibody
N. Nordman, J. Valjakka, M. Peräkylä
2002Proteins: Structure, Function, and Bioinformatics8 citations
Semantic Scholar
Sc L X-ray emission from pure metal and Sc2O3
J. Utriainen, J. Valjakka, M. Linkoaho
19757 citations Open access
Semantic Scholar
THE CRYSTAL STRUCTURE OF A RECOMBINANT ANTI-TESTOSTERONE Fab FRAGMENT IN FREE AND TESTOSTERONE-BOUND FORMS*
J. Valjakka, Kristiina Takkinenz, T. Teerinen, J. Rouvinen
20026 citations
Semantic Scholar
X-ray studies of recombinant anti-testosterone Fab fragments: the use of PEG 3350 in crystallization.
J. Valjakka, A. Hemminki, Tuija Teerinen, Kristiina Takkinen +1 more
2000Acta Crystallographica Section D: Biological Crystallography6 citations
Semantic Scholar
Details of the extended low energy structure in the oxygen K emission spectrum from MgO and CaO
M. Linkoaho, J. Utriainen, J. Valjakka
19765 citations
Semantic Scholar
Oxygen KLL radiative Auger transitions in alkaline-earth oxides
J. Valjakka, J. Utriainen
19863 citations Open access
Semantic Scholar
Configuration interaction in the chlorine L2,3 radiative Auger spectrum of alkali chlorides
J. Valjakka, J. Utriainen
19833 citations
Semantic Scholar
Hepcidin is potential regulator for renin activity
Jaakko Piesanen, J. Valjakka, Sanna Niemelä, Marjut Borgenström +4 more
2022PLoS ONE2 citations Open access
Semantic Scholar
Configuration interaction and double-ionisation satellites in the potassium L2,3 spectrum of potassium halides
J. Valjakka
19862 citations Open access
Semantic Scholar
Structure of 20K-endoglucanase from Melanocarpus albomyces at 1.8 A
J. Valjakka, J. Rouvinen
20031 citations
Semantic Scholar
Crystal Structure Analysis of the Anti-testosterone Fab in Complex with Testosterone
J. Valjakka, A. Hemminki, S. Niemi, H. Soderlund +2 more
20021 citations
Semantic Scholar
Effect of Glu235Ser on enzyme performance and in vitro characterization of human β-glucocerebrosidase in a Pichia pastoris.
Serpil Bayraktar, Arzu Aysan, Ossi Turunen, J. Valjakka +1 more
2026International Journal of Biological Macromolecules0 citations Open access
Semantic Scholar
Corrigendum to "Novel Thermus thermophilus L-Alanine dehydrogenase mutants: Synthesis of L-alanine derivatives with reductive amination" [Int. J. Biol. Macromol. 319 (2025) 145507].
Ğarip Demir, J. Valjakka, Ossi Turunen, Deniz Yildirim +1 more
2025International Journal of Biological Macromolecules0 citations
Semantic Scholar
Deciphering metal ion preference and primary coordination sphere robustness of a designed zinc finger with high‐resolution mass spectrometry
Mikko Laitaoja, Sari Isoniemi, J. Valjakka, I. Mándity +1 more
2017Protein Science0 citations Open access
Semantic Scholar
Reaction specificity of E.Coli L-fucose isomerase
O. Turunen, J. Valjakka, Anne Usvalampi, O. Pastinen +1 more
20110 citations
Semantic Scholar
Monophosphoinositides Zinc-dependent Module and Sap30l and Sap30 Are Mediated by a Dna-binding and -bending Activities of Supplemental Material
Olli Heinonen, J. Valjakka, M. Bulyk, M. Mäki +4 more
20080 citations
Semantic Scholar
Why the Chou-Fasman parameters are not reliable in protein secondary structure prediction
J. Valjakka
20070 citations
Semantic Scholar
Crystal Structure Analysis of the anti-testosterone Fab fragment
J. Valjakka, A. Hemminki, S. Niemi, H. Söderlund +2 more
20020 citations
Semantic Scholar
TESTOSTERONE COMPLEX STRUCTURE OF THE RECOMBINANT MONOCLONAL WILD TYPE ANTI-TESTOSTERONE FAB FRAGMENT
J. Valjakka, Kristiina Takkinenz, T. Teerinen, H. Söderlund +1 more
20020 citations
Semantic Scholar
NATIVE CRYSTAL STRUCTURE OF THE RECOMBINANT MONOCLONAL WILD TYPE ANTI-TESTOSTERONE FAB FRAGMENT
J. Valjakka, Kristiina Takkinenz, T. Teerinen, H. Söderlund +1 more
20020 citations
Semantic Scholar

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