Researcher profile · Semantic Scholar

F. Brembeck

h-index: 20
Works: 29
Citations: 5,038

Most-cited papers

A human protein-protein interaction network: a resource for annotating the proteome.
U. Stelzl, U. Worm, M. Lalowski, C. Haenig +19 more
2005Cell2,485 citations Open access
Semantic Scholar
Balancing cell adhesion and Wnt signaling, the key role of β-catenin
F. Brembeck, M. Rosário, W. Birchmeier
2006629 citations
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Balancing cell adhesion and Wnt signaling, the key role of beta-catenin.
F. Brembeck, M. Rosário, W. Birchmeier
2006Current Opinion in Genetics and Development415 citations
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Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions.
F. Brembeck, T. Schwarz-Romond, J. Bakkers, S. Wilhelm +2 more
2004Genes & Development359 citations Open access
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The mutant K-ras oncogene causes pancreatic periductal lymphocytic infiltration and gastric mucous neck cell hyperplasia in transgenic mice.
F. Brembeck, F. Schreiber, T. Deramaudt, Linden E. Craig +6 more
2003Cancer Research196 citations
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A colorectal cancer expression profile that includes transforming growth factor beta inhibitor BAMBI predicts metastatic potential.
J. Fritzmann, M. Morkel, D. Besser, J. Budczies +6 more
2009Gastroenterology140 citations Open access
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The tissue-dependent keratin 19 gene transcription is regulated by GKLF/KLF4 and Sp1.
F. Brembeck, Anil K. Rustgi
2000Journal of Biological Chemistry129 citations Open access
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Activation of protein kinase Calpha inhibits growth of pancreatic cancer cells via p21(cip)-mediated G(1) arrest.
K. Detjen, F. Brembeck, M. Welzel, A. Kaiser +3 more
2000Journal of Cell Science95 citations
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The keratin 19 promoter is potent for cell-specific targeting of genes in transgenic mice.
F. Brembeck, Jennifer Moffett, Timothy C. Wang, Anil K. Rustgi
2000Gastroenterology73 citations Open access
Semantic Scholar
Molecular mechanism of interferon alfa-mediated growth inhibition in human neuroendocrine tumor cells.
K. Detjen, M. Welzel, K. Farwig, F. Brembeck +4 more
2000Gastroenterology69 citations
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Dual function of the epithelial specific ets transcription factor, ELF3, in modulating differentiation
F. Brembeck, O. Opitz, T. Libermann, A. Rustgi
2000Oncogene65 citations
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Retinoids: effects on growth, differentiation, and nuclear receptor expression in human pancreatic carcinoma cell lines.
S. Rosewicz, Ute Stier, F. Brembeck, A. Kaiser +4 more
1995Gastroenterology65 citations
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BCL9-2 promotes early stages of intestinal tumor progression.
F. Brembeck, M. Wiese, Nathalie Zatula, T. Grigoryan +3 more
2011Gastroenterology56 citations Open access
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A Phase II pilot trial of 13‐cis retinoic acid and interferon‐α in patients with advanced pancreatic carcinoma
F. Brembeck, K. Schoppmeyer, Ursula Leupold, C. Gornistu +4 more
1998Cancer48 citations Open access
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Tumor stroma-derived Wnt5a induces differentiation of basal cell carcinoma of Ptch-mutant mice via CaMKII.
F. Nitzki, A. Zibat, Simone König, M. Wijgerde +11 more
2010Cancer Research41 citations Open access
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Differential growth regulation by all-trans retinoic acid is determined by protein kinase C alpha in human pancreatic carcinoma cells.
S. Rosewicz, F. Brembeck, A. Kaiser, Z. V. Marschall +1 more
1996Endocrinology34 citations Open access
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Peer Review #2 of "Identification of potential biomarkers and pivotal biological pathways for prostate cancer using bioinformatics analysis methods (v0.2)"
Zi-Hao He, Xiao-Lu Duan, Guo-Hua Zeng, Along Gou +404 more
201924 citations Open access
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All-trans-Retinoic Acid-mediated Growth Inhibition Involves Inhibition of Human Kinesin-related Protein HsEg5*
A. Kaiser, F. Brembeck, B. Nicke, B. Wiedenmann +2 more
1999Journal of Biological Chemistry24 citations Open access
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The role of Pygo2 for Wnt/ß-catenin signaling activity during intestinal tumor initiation and progression
S. B. Talla, F. Brembeck
2016OncoTarget23 citations Open access
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The BCL9-2 proto-oncogene governs estrogen receptor alpha expression in breast tumorigenesis
Nathalie Zatula, M. Wiese, Jens Bunzendahl, W. Birchmeier +3 more
2014OncoTarget22 citations Open access
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Retinoic acid receptor alpha mediates growth inhibition by retinoids in rat pancreatic carcinoma DSL-6A/C1 cells.
F. Brembeck, A. Kaiser, K. Detjen, H. Hotz +4 more
1998British Journal of Cancer17 citations Open access
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Fra‐1: a novel target for retinoid action
A. Kaiser, F. Brembeck, Zofia V. Marschall, E. Riecken +2 more
1999FEBS Letters14 citations
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Canonical WNT/β-Catenin Signaling Plays a Subordinate Role in Rhabdomyosarcomas
Nada Ragab, F. Viehweger, J. Bauer, Natalie Geyer +8 more
2018Frontiers in Pediatrics11 citations Open access
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Advances in Brief The Mutant Kras Oncogene Causes Pancreatic Periductal Lymphocytic Infiltration and Gastric Mucous Neck Cell Hyperplasia in Transgenic Mice 1
F. Brembeck, F. Schreiber, T. Deramaudt, Linden E. Craig +6 more
20032 citations
Semantic Scholar
Protein kinase C α inhibits growth of human pancreatic carcinoma cells via P21WAF-mediated inhibition of CDK2 activity
K. Detjen, F. Brembeck, A. Kaiser, E. Riecken +1 more
19981 citations Open access
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The co-activators of de-regulated Wnt/ß-catenin signaling, BCL9-2 and Pygo2, are potential targets for colon cancer therapy
M. Wiese, S. B. Talla, Nadine Schelp, S. Robine +3 more
20160 citations Open access
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K-ras transgenic mouse model recapitulates early pancreatic ductal carcinogenesis
F. Brembeck, F. Schreiber, Linden E. Craig, A. Rustgi
20010 citations
Semantic Scholar
Interplay of GKLF (KLF4) and SP1 in the transcriptional regulation of the keratin 19 gene is tissuedependent
F. Brembeck, A. Rustgi
20000 citations Open access
Semantic Scholar
A phase II trial of 13-cis retinoic acid and interferon-α in UICC stage III/IV pancreatic cancer
F. Brembeck, K. Schoppmeyer, U. Leupold, C. Gornistu +4 more
19980 citations Open access
Semantic Scholar

A. Rustgi

×5

K. Detjen×4

F. Schreiber×3

Linden E. Craig×3

B. Wiedenmann×3

E. Riecken×3

M. Wiese×3

U. Stelzl×2