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R. Crowder · SciRah

Researcher profile · Semantic Scholar

R. Crowder

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R. Crowder — researcher profile on SciRah

h-index: 25
Works: 56
Citations: 5,813

Most-cited papers

Genome Remodeling in a Basal-like Breast Cancer Metastasis and Xenograft
L. Ding, M. Ellis, Shun-Qiang Li, D. Larson +65 more
2010Nature1,201 citations Open access
Semantic Scholar
Whole Genome Analysis Informs Breast Cancer Response to Aromatase Inhibition
M. Ellis, L. Ding, D. Shen, Jingqin R Luo +55 more
2012Nature1,078 citations Open access
Semantic Scholar
Endocrine-Therapy-Resistant ESR1 Variants Revealed by Genomic Characterization of Breast-Cancer-Derived Xenografts
Shun-Qiang Li, D. Shen, Jieya Shao, R. Crowder +51 more
2013Cell Reports640 citations Open access
Semantic Scholar
Phosphatidylinositol 3-Kinase and Akt Protein Kinase Are Necessary and Sufficient for the Survival of Nerve Growth Factor-Dependent Sympathetic Neurons
R. Crowder, R. Freeman
1998Journal of Neuroscience595 citations Open access
Semantic Scholar
Lower-dose (6 mg Daily) versus High-dose (30 mg Daily) Oral Estradiol Therapy of Hormone-receptor-positive, Aromatase-inhibitor-resistant Advanced Breast Cancer: A Randomized Phase 2 Study
M. Ellis, Feng Gao, F. Dehdashti, D. Jeffe +9 more
2009Journal of the American Medical Association (JAMA)279 citations Open access
Semantic Scholar
PIK3CA and PIK3CB inhibition produce synthetic lethality when combined with estrogen deprivation in estrogen receptor positive breast cancer
R. Crowder, C. Phommaly, Y. Tao, J. Hoog +13 more
2009Cancer Research208 citations Open access
Semantic Scholar
Glycogen Synthase Kinase-3β Activity Is Critical for Neuronal Death Caused by Inhibiting Phosphatidylinositol 3-Kinase or Akt but Not for Death Caused by Nerve Growth Factor Withdrawal*
R. Crowder, R. Freeman
2000Journal of Biological Chemistry197 citations Open access
Semantic Scholar
Preclinical modeling of combined phosphatidylinositol-3-kinase inhibition with endocrine therapy for estrogen receptor-positive breast cancer
Cesar G. Sanchez, Cynthia X. Ma, R. Crowder, Therese Guintoli +4 more
2011Breast Cancer Research187 citations Open access
Semantic Scholar
Efficacy of SERD/SERM Hybrid-CDK4/6 inhibitor combinations in models of endocrine therapy resistant breast cancer
S. Wardell, M. Ellis, Holly M. Alley, Koleen Eisele +11 more
2015Clinical Cancer Research134 citations Open access
Semantic Scholar
The Long and Short Isoforms of Ret Function as Independent Signaling Complexes*
Brian A. Tsui-Pierchala, Rebecca C. Ahrens, R. Crowder, J. Milbrandt +1 more
2002Journal of Biological Chemistry131 citations Open access
Semantic Scholar
Phosphatidyl-inositol-3-kinase alpha catalytic subunit mutation and response to neoadjuvant endocrine therapy for estrogen receptor positive breast cancer
M. Ellis, Li Lin, R. Crowder, Y. Tao +14 more
2010Breast Cancer Research and Treatment126 citations Open access
Semantic Scholar
Dok-6, a Novel p62 Dok Family Member, Promotes Ret-mediated Neurite Outgrowth*
R. Crowder, H. Enomoto, Mao Yang, E. M. Johnson +1 more
2004Journal of Biological Chemistry122 citations Open access
Semantic Scholar
Tyrosine 981, a Novel Ret Autophosphorylation Site, Binds c-Src to Mediate Neuronal Survival*
M. Encinas, R. Crowder, J. Milbrandt, E. M. Johnson
2004Journal of Biological Chemistry116 citations Open access
Semantic Scholar
Relationship between plasma estradiol levels and estrogen-responsive gene expression in estrogen receptor-positive breast cancer in postmenopausal women.
A. Dunbier, H. Anderson, Z. Ghazoui, E. Folkerd +10 more
2010Journal of Clinical Oncology107 citations Open access
Semantic Scholar
NGF deprivation-induced gene expression: after ten years, where do we stand?
R. Freeman, Robert L. Burch, R. Crowder, David J. Lomb +3 more
2004Progress in Brain Research98 citations
Semantic Scholar
Functional Annotation of ESR1 Gene Fusions in Estrogen Receptor-Positive Breast Cancer
Jonathan T. Lei, Jieya Shao, Jin Zhang, M. Iglesia +39 more
2018Cell Reports96 citations Open access
Semantic Scholar
Expression of the SM‐20 Gene Promotes Death in Nerve Growth Factor‐Dependent Sympathetic Neurons
Elizabeth A. Lipscomb, Patrick D. Sarmiere, R. Crowder, R. Freeman
1999Journal of Neurochemistry82 citations
Semantic Scholar
A Phase I Study of the AKT Inhibitor MK-2206 in Combination with Hormonal Therapy in Postmenopausal Women with Estrogen Receptor Positive Metastatic Breast Cancer
Cynthia X. Ma, Cesar G. Sanchez, Feng Gao, R. Crowder +9 more
2016Clinical Cancer Research71 citations Open access
Semantic Scholar
Long-range function of secreted small nucleolar RNAs that direct 2′-O-methylation
Jamie M. Rimer, Jiyeon Lee, C. Holley, R. Crowder +4 more
2018Journal of Biological Chemistry59 citations Open access
Semantic Scholar
The Survival of Sympathetic Neurons Promoted by Potassium Depolarization, but Not by Cyclic AMP, Requires Phosphatidylinositol 3‐Kinase and Akt
R. Crowder, R. Freeman
1999Journal of Neurochemistry55 citations
Semantic Scholar
Importance of PI3-kinase pathway in response/resistance to aromatase inhibitors.
Cynthia X. Ma, R. Crowder, M. Ellis
2011Steroids53 citations
Semantic Scholar
Cytosine arabinoside rapidly activates Bax-dependent apoptosis and a delayed Bax-independent death pathway in sympathetic neurons
C. Besirli, T. Deckwerth, R. Crowder, R. Freeman +1 more
2003Cell Death and Differentiation46 citations
Semantic Scholar
Successful targeting of ErbB2 receptors-is PTEN the key?
R. Crowder, Donald P. Lombardi, M. Ellis
2004Cancer Cell30 citations Open access
Semantic Scholar
Treating breast cancer through novel inhibitors of the phosphatidylinositol 3'-kinase pathway
R. Crowder, M. Ellis
2005Breast Cancer Research29 citations Open access
Semantic Scholar
ER and PI3K independently modulate endocrine resistance in ER positive breast cancer
B. Van Tine, R. Crowder, M. Ellis
2011Cancer Discovery26 citations Open access
Semantic Scholar
31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two
C. Ager, M. Reilley, C. Nicholas, Todd Bartkowiak +496 more
2016Journal for ImmunoTherapy of Cancer18 citations Open access
Semantic Scholar
A randomized phase 2 trial of low dose (6 mg daily) versus high dose (30 mg daily) estradiol for patients with estrogen receptor positive aromatase inhibitor resistant advanced breast cancer.
M. J. Ellis, F. Dehdahti, A. Kommareddy, S. Jamalabadi-Majidi +8 more
200910 citations
Semantic Scholar
Abstract S3-05: Patient-derived xenograft study reveals endocrine therapy resistance of ER+ breast cancer caused by distinct ESR1 gene aberrations
Jieya Shao, Shu-Hong Li, R. Crowder, R. Kitchens +8 more
20134 citations
Semantic Scholar
Reaction of trifluoroacetaldehyde with amino acids, nucleotides, lipid nucleophiles, and their analogs.
He-Qun Yin, R. Crowder, Jeffrey P. Jones, M. W. Anders
1996Chemical Research in Toxicology4 citations
Semantic Scholar
Morphology of the male system and spermatophores of the arrowworm Ferosagitta hispida (Chaetognatha)
M. Bergey, R. Crowder, G. L. Shinn
1994Journal of morphology4 citations
Semantic Scholar
Assessment of CCR2 PET as a Biomarker for Head and Neck Squamous Cell Carcinoma
Alexandria Li, Deborah Sultan, G. Heo, L. Detering +19 more
2026Journal of Nuclear Medicine2 citations
Semantic Scholar
Expression of the leukocyte chemoattractant chemerin in human prostate tumors.
R. Pachynski, Brian A. Zabel, Weng-In Leong, R. Crowder +2 more
20152 citations
Semantic Scholar
Abstract PD6-4: ESR1 gene fusions implicated in endocrine therapy resistance of ER+ breast cancer
Jieya Shao, Jin Zhang, R. Crowder, R. Gonçalves +6 more
20151 citations
Semantic Scholar
Abstract 5544: Patient-derived xenograft study reveals the pharmacology and the role of ESR1 gene aberrations in endocrine therapy resistance of ER positive breast cancer
T. Sen, Shun-Qiang Li, Jieya Shao, R. Crowder +2 more
20141 citations
Semantic Scholar
The Effect of the IGF1R Antibody R1507 on ER Positive Breast Cancer Cell Lines Growth and Survival.
Cesar G. Sanchez, R. Crowder, C. Phommaly, M. Ellis
20091 citations
Semantic Scholar
Phosphatidyl-inositol-3-kinase Alpha catalytic subunit kinase domain mutations impart a favorable prognosis on estrogen receptor positive breast cancer through a mechanism that is independent of responsiveness to endocrine treatment.
M. Ellis, L. Lin, R. Crowder, Y. Tao +7 more
20091 citations
Semantic Scholar
“PIKing” the Winner for Phosphatidylinositol 3-Kinase Inhibitors in ErbB2-Positive Breast Cancer: Let's Not “PTENed” It's Easy!
M. Ellis, R. Crowder
2007Clinical Cancer Research1 citations Open access
Semantic Scholar
PET Imaging of Tumor-Associated Macrophage Dynamics and Response to Clinical Treatment for Potential Translation.
G. Heo, Alexandria Li, Joan Tao, J. Zaretsky +20 more
2026Journal of Nuclear Medicine0 citations
Semantic Scholar
Evaluating the potential of CCR2 for the early detection of head and neck cancer
Yeona Kang, Alexandria Li, Divangana Lahad, Hannah P. Luehmann +5 more
2023Nuclear Medicine and Biology0 citations
Semantic Scholar
Utility of the ADC Map in Identification of Diffusion Restriction on a Background of Basal Ganglia Iron Deposition
R. Crowder, J. Karis
20190 citations Open access
Semantic Scholar
Abstract 5240: Functional and therapeutic significance ofESR1gene fusions in breast cancer
Jonathan T. Lei, Jieya Shao, Jin Zhang, M. Iglesia +37 more
2018Clinical research0 citations
Semantic Scholar
Effect of the leukocyte chemoattractant chemerin on PTEN via CMKLR1 in human prostate cancer.
R. Pachynski, R. Crowder, William Shin, Keith Rennier
20180 citations
Semantic Scholar
Abstract 3690: The leukocyte chemoattractant chemerin modulates PTEN via CMKLR1 in human tumors
Keith Rennier, Ping Wang, R. Crowder, Russell K Pachynski
20170 citations
Semantic Scholar
SAGEEP 2017 papers with only a paragraph abstract
K. Dickey, C. Finn, W. Holbrook, P. Bedrosian +344 more
20170 citations
Semantic Scholar
Abstract 1033: Estrogen receptor gene fusions drive endocrine therapy resistance in estrogen receptor positive breast cancer
Jonathan T. Lei, Jieya Shao, Jin Zhang, M. Iglesia +28 more
20170 citations
Semantic Scholar
Abstract IA3: PI3K inhibitors in ER+ breast cancer: Next steps
M. Ellis, R. Crowder, Cynthia X. Ma
2012Clinical Cancer Research0 citations
Semantic Scholar
Abstract LB-423: Whole genome comparisons of pre- and post- aromatase inhibitor treatment in estrogen receptor positive breast cancer
M. Ellis, Ding Li, D. Shen, Jingqin R Luo +46 more
20120 citations
Semantic Scholar
Abstract 5478: Combination of fulvestrant with the allosteric Akt inhibitor MK-2206 promotes anti-tumor activity in estrogen deprivation-resistant estrogen receptor positive breast cancer
Cesar G. Sanchez, R. Crowder, C. Phommaly, M. Ellis
20110 citations
Semantic Scholar
Abstract P2-19-01: Modulating Response to Phosphoinositol-3-Kinase/mTOR Inhibition in ER Positive Breast Cancer Cell Lines after Acquired Resistance to Estrogen Deprivation
Cesar G. Sanchez, R. Crowder, C. Phommaly, M. Ellis
20100 citations
Semantic Scholar
Response to phosphoinositol-3-kinase inhibition in ER-positive breast cancer cell lines after acquired resistance to estrogen deprivation.
Cesar G. Sanchez, C. Phommaly, R. Crowder, M. Ellis
20100 citations
Semantic Scholar

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M. Ellis×23
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M. Ellis — researcher profile on SciRah
C. Phommaly×12
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C. Phommaly — researcher profile on SciRah
J. Hoog×11
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J. Hoog — researcher profile on SciRah
C. Perou×9
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M. Watson — researcher profile on SciRah

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Jieya Shao — researcher profile on SciRah

Cynthia X. Ma×8

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Cynthia X. Ma — researcher profile on SciRah

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Y. Tao — researcher profile on SciRah

Shun-Qiang Li×6

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Shun-Qiang Li — researcher profile on SciRah

Sherri R. Davies×6

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Sherri R. Davies — researcher profile on SciRah

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R. Freeman — researcher profile on SciRah

Cesar G. Sanchez×6

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Cesar G. Sanchez — researcher profile on SciRah