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Greg Poffenberger · SciRah

Researcher profile · Semantic Scholar

Greg Poffenberger

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Greg Poffenberger — researcher profile on SciRah

h-index: 28
Works: 66
Citations: 3,677

Most-cited papers

Pancreatic Islet Production of Vascular Endothelial Growth Factor-A Is Essential for Islet Vascularization, Revascularization, and Function
M. Brissova, A. Shostak, M. Shiota, Peter O. Wiebe +12 more
2006Diabetes459 citations
Semantic Scholar
Glucose Metabolism In Vivo in Four Commonly Used Inbred Mouse Strains
E. Berglund, Candice Y. Li, Greg Poffenberger, Julio E. Ayala +5 more
2008Diabetes281 citations Open access
Semantic Scholar
Activation of human T cells in hypertension: Studies of Humanized Mice and Hypertensive Humans
Hana A. Itani, W. McMaster, Mohamed A. Saleh, R. Nazarewicz +15 more
2016HYPERTENSION228 citations Open access
Semantic Scholar
Islet microenvironment, modulated by vascular endothelial growth factor-A signaling, promotes β cell regeneration
M. Brissova, Kristie I. Aamodt, Priyanka P. Brahmachary, Nripesh Prasad +8 more
2014Cell Metabolism222 citations Open access
Semantic Scholar
α Cell Function and Gene Expression Are Compromised in Type 1 Diabetes
M. Brissova, Rachana Haliyur, Diane C. Saunders, Shristi Shrestha +19 more
2018Cell Reports192 citations Open access
Semantic Scholar
Interrupted Glucagon Signaling Reveals Hepatic-α-Cell Axis and Role for L-Glutamine in α-Cell Proliferation
E. D. Dean, Ming-Yu Li, Nripesh Prasad, S. Wisniewski +24 more
2017Cell Metabolism183 citations Open access
Semantic Scholar
Cystic fibrosis-related diabetes is caused by islet loss and inflammation.
Nathaniel J. Hart, R. Aramandla, Greg Poffenberger, Cody Fayolle +17 more
2018JCI Insight168 citations Open access
Semantic Scholar
Tamoxifen-Induced Cre-loxP Recombination Is Prolonged in Pancreatic Islets of Adult Mice
Rachel B. Reinert, Jeannelle Kantz, A. Misfeldt, Greg Poffenberger +3 more
2012PLoS ONE138 citations Open access
Semantic Scholar
Age-dependent human β cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling.
C. Dai, Y. Hang, A. Shostak, Greg Poffenberger +9 more
2017Journal of Clinical Investigation137 citations Open access
Semantic Scholar
Suppression of Insulin Production and Secretion by a Decretin Hormone
Ronald W. Alfa, Sangbin Park, K. Skelly, Greg Poffenberger +7 more
2015Cell Metabolism135 citations Open access
Semantic Scholar
Assessment of Pancreatic Islet Mass after Islet Transplantation Using In Vivo Bioluminescence Imaging
Michael J Fowler, John Virostko, Zhongyi Chen, Greg Poffenberger +9 more
2005Transplantation99 citations Open access
Semantic Scholar
Vascular Endothelial Growth Factor-A and Islet Vascularization Are Necessary in Developing, but Not Adult, Pancreatic Islets
Rachel B. Reinert, M. Brissova, A. Shostak, Fong C. Pan +8 more
2013Diabetes98 citations Open access
Semantic Scholar
Stress-impaired transcription factor expression and insulin secretion in transplanted human islets.
C. Dai, Nora S Kayton, A. Shostak, Greg Poffenberger +12 more
2016Journal of Clinical Investigation97 citations Open access
Semantic Scholar
Human islet preparations distributed for research exhibit a variety of insulin-secretory profiles.
Nora S Kayton, Greg Poffenberger, Joseph Henske, C. Dai +7 more
2015American Journal of Physiology. Endocrinology and Metabolism89 citations Open access
Semantic Scholar
Enhanced expression of VEGF-A in β cells increases endothelial cell number but impairs islet morphogenesis and β cell proliferation
Qing Cai, M. Brissova, Rachel B. Reinert, Fong C. Pan +9 more
2012Developmental Biology83 citations Open access
Semantic Scholar
Ectonucleoside triphosphate diphosphohydrolase-3 antibody targets adult human pancreatic β-cells for in vitro and in vivo analysis
Diane C. Saunders, M. Brissova, Neil Phillips, Shristi Shrestha +19 more
2018Cell Metabolism78 citations Open access
Semantic Scholar
β-Cell Replacement in Mice Using Human Type 1 Diabetes Nuclear Transfer Embryonic Stem Cells
Lina Sui, N. Danzl, Sean R Campbell, Ryan Viola +12 more
2017Diabetes76 citations Open access
Semantic Scholar
Genetic risk converges on regulatory networks mediating early type 2 diabetes
John T. Walker, Diane C. Saunders, Vivek Rai, Hung-Hsin Chen +29 more
2023Nature73 citations Open access
Semantic Scholar
Age-Dependent Decline in the Coordinated [Ca2+] and Insulin Secretory Dynamics in Human Pancreatic Islets
Matthew J. Westacott, Nikki L. Farnsworth, Joshua R. St. Clair, Greg Poffenberger +5 more
2017Diabetes71 citations Open access
Semantic Scholar
Bioluminescence Imaging in Mouse Models Quantifies β Cell Mass in the Pancreas and After Islet Transplantation
John Virostko, A. Radhika, Greg Poffenberger, Zhongyi Chen +6 more
2009Molecular Imaging and Biology69 citations Open access
Semantic Scholar
Human islets expressing HNF1A variant have defective &bgr; cell transcriptional regulatory networks
Rachana Haliyur, Xin Tong, May Sanyoura, Shristi Shrestha +14 more
2018Journal of Clinical Investigation67 citations Open access
Semantic Scholar
The PGE2 EP3 Receptor Regulates Diet-Induced Adiposity in Male Mice.
Ryan P. Ceddia, Daekee Lee, M. Maulis, Bethany A. Carboneau +8 more
2016Endocrinology65 citations Open access
Semantic Scholar
Tacrolimus- and sirolimus-induced human β cell dysfunction is reversible and preventable.
C. Dai, John T. Walker, A. Shostak, A. Padgett +11 more
2020JCI Insight63 citations Open access
Semantic Scholar
Factors influencing quantification of in vivo bioluminescence imaging: application to assessment of pancreatic islet transplants.
John Virostko, Zhongyi Chen, Michael J Fowler, Greg Poffenberger +2 more
2004Molecular Imaging61 citations Open access
Semantic Scholar
Decreased pancreatic acinar cell number in type 1 diabetes
Jordan J. Wright, Diane C. Saunders, C. Dai, Greg Poffenberger +6 more
2020Diabetologia60 citations Open access
Semantic Scholar
Glucagon blockade restores functional β-cell mass in type 1 diabetic mice and enhances function of human islets
May-yun Wang, E. D. Dean, Ezekiel Quittner-Strom, Yi Zhu +21 more
2021Proceedings of the National Academy of Sciences of the United States of America50 citations Open access
Semantic Scholar
Integrated human pseudoislet system and microfluidic platform demonstrates differences in G-protein-coupled-receptor signaling in islet cells.
John T. Walker, Rachana Haliyur, Heather A. Nelson, Matthew Ishahak +11 more
2020JCI Insight38 citations Open access
Semantic Scholar
Combinatorial transcription factor profiles predict mature and functional human islet α and β cells
Shristi Shrestha, Diane C. Saunders, John T. Walker, J. Camunas-Soler +13 more
2021bioRxiv35 citations Open access
Semantic Scholar
Maintenance of Hepatic Nuclear Factor 6 in Postnatal Islets Impairs Terminal Differentiation and Function of β-Cells
Elizabeth E. Tweedie, I. Artner, Laura A. Crawford, Greg Poffenberger +4 more
2006Diabetes28 citations
Semantic Scholar
Pancreatic Islet Beta Cell-Specific Deletion of G6pc2 Reduces Fasting Blood Glucose
Karin J. Bosma, Mohsin Rahim, Kritika Singh, S. Goleva +12 more
2020Journal of Molecular Endocrinology26 citations Open access
Semantic Scholar
alpha Cell Function and Gene Expression Are Compromised in Type 1 Diabetes
M. Brissova, Rachana Haliyur, Diane C. Saunders, Shristi Shrestha +19 more
201926 citations
Semantic Scholar
Bioluminescence Imaging Reveals Dynamics of Beta Cell Loss in the Non-Obese Diabetic (NOD) Mouse Model
John Virostko, Armandla Radhika, Greg Poffenberger, A. Dula +2 more
2013PLoS ONE24 citations Open access
Semantic Scholar
Activated FoxM1 attenuates streptozotocin-mediated β-cell death.
M. Golson, M. Maulis, Jennifer C. Dunn, Greg Poffenberger +3 more
2014Molecular Endocrinology23 citations Open access
Semantic Scholar
Coordinated interactions between endothelial cells and macrophages in the islet microenvironment promote β cell regeneration
Diane C. Saunders, Kristie I. Aamodt, Tiffany M. Richardson, Alexander J. Hopkirk +8 more
2021npj Regenerative Medicine21 citations Open access
Semantic Scholar
Factor XI protein in human pancreas and kidney
Qiu-Fang Cheng, Jeanelle Kantz, Greg Poffenberger, A. Powers +1 more
2008Thrombosis and Haemostasis14 citations Open access
Semantic Scholar
Coordinated interactions between endothelial cells and macrophages in the islet microenvironment promote β cell regeneration
Diane C. Saunders, Kristie I. Aamodt, Tiffany M. Richardson, Alexander J. Hopkirk +8 more
2020bioRxiv13 citations Open access
Semantic Scholar
Healthy Donor Polyclonal IgMs Diminish B-Lymphocyte Autoreactivity, Enhance Regulatory T-Cell Generation, and Reverse Type 1 Diabetes in NOD Mice
C. S. Wilson, P. Chhabra, A. F. Marshall, C. V. Morr +6 more
2018Diabetes12 citations Open access
Semantic Scholar
Generation of Islet-Like Hormone-Producing Cells In Vitro from Adult Human Pancreas
F. Atouf, Yong-Soo Choi, Michael J Fowler, Greg Poffenberger +5 more
2005Cell Transplantation12 citations Open access
Semantic Scholar
Factors Influencing Quantification of in Vivo Bioluminescence Imaging: Application to Assessment of Pancreatic Islet Transplants
John Virostko, Zhongyi Chen, Michael J Fowler, Greg Poffenberger +2 more
200412 citations Open access
Semantic Scholar
Dapagliflozin does not directly affect human α or β cells.
C. Dai, John T. Walker, A. Shostak, Yasir Bouchi +10 more
2020Endocrinology11 citations Open access
Semantic Scholar
Heterogeneous endocrine cell composition defines human islet functional phenotypes
C. Evans-Molina, Yasminye D. Pettway, Diane C. Saunders, Seth A. Sharp +26 more
2024bioRxiv9 citations Open access
Semantic Scholar
Pancreatic islet α cell function and proliferation requires the arginine transporter SLC7A2
Erick Spears, Jade E. Stanley, Matthew Shou, L. Yin +15 more
2023bioRxiv8 citations Open access
Semantic Scholar
RFX6-mediated dysregulation defines human β cell dysfunction in early type 2 diabetes
John T. Walker, Diane C. Saunders, Vivek Rai, C. Dai +22 more
2021bioRxiv7 citations Open access
Semantic Scholar
Mapping histologic and functional maturation of human endocrine pancreas across early postnatal periods
Diane C. Saunders, Nathaniel Hart, Fong C. Pan, Conrad V. Reihsmann +25 more
2024bioRxiv6 citations
Semantic Scholar
Heterogeneous endocrine cell composition defines human islet functional phenotypes
C. Evans-Molina, Yasminye D. Pettway, Diane C. Saunders, Seth A. Sharp +26 more
2026Nature Communications4 citations Open access
Semantic Scholar
Interruption of glucagon signaling augments islet non-alpha cell proliferation in SLC7A2- and mTOR-dependent manners
Katie C. Coate, Chun-Hua Dai, Ajay Singh, Jade E. Stanley +18 more
2024Molecular Metabolism4 citations Open access
Semantic Scholar
Exploiting LY3009120 and Asciminib Combination to Target TKI-Resistant CML
Milad Rouhimoghadam, A. Pomicter, Alexandria Van Scoyk, Greg Poffenberger +5 more
2021Blood3 citations Open access
Semantic Scholar
Pancreatic islet α cell function and proliferation require the arginine transporter SLC7A2
Erick Spears, Jade E. Stanley, Matthew Shou, L. Yin +18 more
2026Journal of Clinical Investigation2 citations Open access
Semantic Scholar
Mapping histologic and functional maturation of human endocrine pancreas across early postnatal periods
Diane C. Saunders, Fan Feng, Alexander L. Hopkirk, Kristie I. Aamodt +31 more
2026Nature Communications2 citations Open access
Semantic Scholar
Integrated Analysis of the Pancreas and Islets Reveals Unexpected Findings in Human Male With Type 1 Diabetes
Rachana Haliyur, John T. Walker, May Sanyoura, Conrad V. Reihsmann +14 more
2021Journal of the Endocrine Society2 citations Open access
Semantic Scholar

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