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R. A. Howlett · SciRah

Researcher profile · Semantic Scholar

R. A. Howlett

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R. A. Howlett — researcher profile on SciRah

h-index: 30
Works: 80
Citations: 2,842

Most-cited papers

Loss of Skeletal Muscle HIF-1α Results in Altered Exercise Endurance
Steven D. Mason, R. A. Howlett, Matthew J. Kim, I. Olfert +7 more
2004PLoS Biology216 citations Open access
Semantic Scholar
An enzymatic approach to lactate production in human skeletal muscle during exercise.
L. Spriet, R. A. Howlett, G. Heigenhauser
2000Medicine & Science in Sports & Exercise209 citations Open access
Semantic Scholar
Regulation of skeletal muscle glycogen phosphorylase and PDH at varying exercise power outputs.
R. A. Howlett, M. L. Parolin, D. Dyck, E. Hultman +3 more
1998American Journal of Physiology187 citations Open access
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Muscle‐specific VEGF deficiency greatly reduces exercise endurance in mice
I. Olfert, R. A. Howlett, Ke-Chun Tang, Nancy D. Dalton +4 more
2009Journal of Physiology170 citations Open access
Semantic Scholar
Sensitivity of CPT I to malonyl-CoA in trained and untrained human skeletal muscle.
E. Starritt, R. A. Howlett, G. Heigenhauser, L. Spriet
2000American Journal of Physiology. Endocrinology and Metabolism133 citations
Semantic Scholar
Myocyte vascular endothelial growth factor is required for exercise-induced skeletal muscle angiogenesis.
I. Olfert, R. A. Howlett, P. Wagner, E. Breen
2010American Journal of Physiology. Regulatory Integrative and Comparative Physiology130 citations Open access
Semantic Scholar
Effects of dichloroacetate infusion on human skeletal muscle metabolism at the onset of exercise.
R. A. Howlett, G. Heigenhauser, E. Hultman, M. G. Hollidge-Horvat +1 more
1999American Journal of Physiology. Endocrinology and Metabolism120 citations
Semantic Scholar
HIF-1α in Endurance Training: Suppression of Oxidative Metabolism
Steven D. Mason, H. Rundqvist, I. Papandreou, Roger Duh +7 more
2007115 citations
Semantic Scholar
Skeletal muscle malonyl-CoA content at the onset of exercise at varying power outputs in humans.
L. Odland, R. A. Howlett, G. Heigenhauser, E. Hultman +1 more
1998American Journal of Physiology. Endocrinology and Metabolism114 citations
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Human skeletal muscle carnitine palmitoyltransferase I activity determined in isolated intact mitochondria.
P. Berthon, R. A. Howlett, G. Heigenhauser, L. Spriet
1998Journal of applied physiology111 citations Open access
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Selected contribution: skeletal muscle capillarity and enzyme activity in rats selectively bred for running endurance.
R. A. Howlett, N. Gonzalez, H. Wagner, Z. Fu +3 more
2003Journal of applied physiology110 citations
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Regulation of muscle glycogenolytic flux during intense aerobic exercise after caffeine ingestion.
A. Chesley, R. A. Howlett, G. Heigenhauser, E. Hultman +1 more
1998American Journal of Physiology. Regulatory Integrative and Comparative Physiology93 citations
Semantic Scholar
Effects of acute creatine kinase inhibition on metabolism and tension development in isolated single myocytes.
C. Kindig, R. A. Howlett, C. Stary, Brandon Walsh +1 more
2005Journal of applied physiology79 citations
Semantic Scholar
Kinetic control of oxygen consumption during contractions in self‐perfused skeletal muscle
R. Wüst, B. Grassi, Michael C. Hogan, R. A. Howlett +2 more
2011Journal of Physiology74 citations Open access
Semantic Scholar
HIF-1alpha in endurance training: suppression of oxidative metabolism.
Steven D. Mason, H. Rundqvist, I. Papandreou, Roger Duh +7 more
2007American Journal of Physiology. Regulatory Integrative and Comparative Physiology64 citations
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Continued divergence in VO2max of rats artificially selected for running endurance is mediated by greater convective blood O2 delivery.
N. Gonzalez, Scott D. Kirkton, R. A. Howlett, S. Britton +3 more
2006Journal of applied physiology64 citations
Semantic Scholar
Human skeletal muscle pyruvate dehydrogenase kinase activity increases after a low-carbohydrate diet.
S. J. Peters, T. S. St. Amand, R. A. Howlett, G. Heigenhauser +1 more
1998American Journal of Physiology. Endocrinology and Metabolism64 citations
Semantic Scholar
Effect of extracellular PO2 on the fall in intracellular PO2 in contracting single myocytes.
C. Kindig, R. A. Howlett, M. Hogan
2003Journal of applied physiology58 citations
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Peripheral oxygen transport and utilization in rats following continued selective breeding for endurance running capacity.
R. A. Howlett, Scott D. Kirkton, N. Gonzalez, H. Wagner +3 more
2009Journal of applied physiology57 citations Open access
Semantic Scholar
Effects of nitric oxide synthase inhibition by l‐NAME on oxygen uptake kinetics in isolated canine muscle in situ
B. Grassi, Michael C. Hogan, K. Kelley, R. A. Howlett +1 more
2005Journal of Physiology53 citations
Semantic Scholar
Assessment of O2 uptake dynamics in isolated single skeletal myocytes.
C. Kindig, K. Kelley, R. A. Howlett, C. Stary +1 more
2003Journal of applied physiology52 citations
Semantic Scholar
Age is no barrier to muscle structural, biochemical and angiogenic adaptations to training up to 24 months in female rats
H. Rossiter, R. A. Howlett, H. Holcombe, P. Entin +2 more
2005Journal of Physiology49 citations
Semantic Scholar
Measurement of activation energy and oxidative phosphorylation onset kinetics in isolated muscle fibers in the absence of cross-bridge cycling.
Brandon Walsh, R. A. Howlett, C. Stary, C. Kindig +1 more
2006American Journal of Physiology. Regulatory Integrative and Comparative Physiology43 citations
Semantic Scholar
Continued artificial selection for running endurance in rats is associated with improved lung function.
Scott D. Kirkton, R. A. Howlett, N. Gonzalez, P. Giuliano +4 more
2009Journal of applied physiology39 citations Open access
Semantic Scholar
Skeletal muscle metabolism during high-intensity sprint exercise is unaffected by dichloroacetate or acetate infusion.
R. A. Howlett, G. Heigenhauser, L. Spriet
1999Journal of applied physiology38 citations
Semantic Scholar
Faster O2 uptake kinetics in canine skeletal muscle in situ after acute creatine kinase inhibition
B. Grassi, H. Rossiter, Michael C. Hogan, R. A. Howlett +4 more
2011Journal of Physiology36 citations Open access
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Dichloroacetate accelerates the fall in intracellular PO2 at onset of contractions in Xenopus single muscle fibers.
R. A. Howlett, M. Hogan
2003American Journal of Physiology. Regulatory Integrative and Comparative Physiology36 citations
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Preconditioning improves function and recovery of single muscle fibers during severe hypoxia and reoxygenation.
Suzanne Kohin, C. Stary, R. A. Howlett, Michael C. Hogan
2001American Journal of Physiology - Cell Physiology34 citations
Semantic Scholar
The O2 cost of the tension-time integral in isolated single myocytes during fatigue.
R. Hepple, R. A. Howlett, C. Kindig, C. Stary +1 more
2010American Journal of Physiology. Regulatory Integrative and Comparative Physiology32 citations Open access
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Effect of hypoxia on fatigue development in rat muscle composed of different fibre types
R. A. Howlett, Michael C. Hogan
2007Experimental Physiology30 citations Open access
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Intracellular PO(2) decreases with increasing stimulation frequency in contracting single Xenopus muscle fibers.
R. A. Howlett, Michael C. Hogan
2001Journal of applied physiology29 citations
Semantic Scholar
Systemic oxygen transport in rats artificially selected for running endurance.
N. Gonzalez, R. A. Howlett, K. Henderson, L. Koch +4 more
2006Respiratory Physiology & Neurobiology22 citations
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Continued divergence in V̇O 2 max of rats artificially selected for running endurance is mediated by greater convective blood O 2 delivery
N. Gonzalez, Scott D. Kirkton, R. A. Howlett, S. Britton +3 more
200619 citations
Semantic Scholar
Fiber-type-related differences in the enzymes of a proposed substrate cycle.
R. A. Howlett, Wayne T. Willis
1998Biochimica et Biophysica Acta19 citations Open access
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Caffeine administration results in greater tension development in previously fatigued canine muscle in situ
R. A. Howlett, K. Kelley, B. Grassi, L. Gladden +1 more
2005Experimental Physiology17 citations Open access
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Determinants of oxidative phosphorylation onset kinetics in isolated myocytes.
Brandon Walsh, R. A. Howlett, C. Stary, C. Kindig +1 more
2005Medicine & Science in Sports & Exercise17 citations Open access
Semantic Scholar
Relationship between intracellular PO2 recovery kinetics and fatigability in isolated single frog myocytes.
C. Kindig, Brandon Walsh, R. A. Howlett, C. Stary +1 more
2005Journal of applied physiology14 citations
Semantic Scholar
Human skeletal muscle pyruvate dehydrogenase kinase activity increases after a low-carbohydrate diet.
S. J. Peters, T. S. St. Amand, R. A. Howlett, G. Heigenhauser +1 more
1998American Journal of Physiology14 citations
Semantic Scholar
Intracellular PO2 kinetics at different contraction frequencies in Xenopus single skeletal muscle fibers.
R. A. Howlett, C. Kindig, M. Hogan
2007Journal of applied physiology12 citations
Semantic Scholar
Nitric oxide synthase inhibition reduces O2 cost of force development and spares high‐energy phosphates following contractions in pump‐perfused rat hindlimb muscles
D. J. Baker, D. J. Krause, R. A. Howlett, R. Hepple
2006Experimental Physiology12 citations Open access
Semantic Scholar
Effect of contractile duration on intracellular PO2 kinetics in Xenopus single skeletal myocytes.
C. Kindig, R. A. Howlett, M. Hogan
2005Journal of applied physiology11 citations
Semantic Scholar
Glycolytic activation at the onset of contractions in isolated Xenopus laevis single myofibres
Brandon Walsh, C. Stary, R. A. Howlett, K. Kelley +1 more
2008Experimental Physiology9 citations Open access
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Trimetazidine Reduces Basal Cytosolic Ca2+ Concentration During Hypoxia in Single Xenopus Skeletal Myocytes
C. Stary, Suzanne Kohin, Michele Samaja, R. A. Howlett +1 more
2003Experimental Physiology8 citations Open access
Semantic Scholar
Effects of Acute Creatine Kinase Inhibition on Skeletal Muscle O2 Uptake Kinetics: 2710
B. Grassi, M. Hogan, H. Rossiter, R. A. Howlett +4 more
20067 citations Open access
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Recovery of force during postcontractile depression in single Xenopus muscle fibers.
R. A. Howlett, C. Stary, Michael C. Hogan
2001American Journal of Physiology. Regulatory Integrative and Comparative Physiology6 citations
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Intracellular P O 2 decreases with increasing stimulation frequency in contracting single Xenopus muscle ﬁbers
R. A. Howlett, M. Hogan
20013 citations
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Chapter 28. Caffeine
L. Spriet, R. A. Howlett
20082 citations
Semantic Scholar
EFFECTS OF L-NAME DURING METABOLIC TRANSITIONS IN ISOLATED CANINE MUSCLE
B. Grassi, M. Hogan, K. Kelley, R. A. Howlett +2 more
20032 citations Open access
Semantic Scholar
HUMAN SKELETAL MUSCLE CPT-I ACTIVITY DETERMINED IN ISOLATED INTACT MITOCHONDRIA
R. A. Howlett, P. Berthon, G. Heigenhauser, L. Spriet
19982 citations
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Implications of rapid early oxygen consumption in exercising skeletal muscle: The empirical, the theoretical and the rational
R. Wüst, B. Grassi, Michael C. Hogan, R. A. Howlett +2 more
20111 citations Open access
Semantic Scholar

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L. Spriet×10
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