Researcher profile · Semantic Scholar

Siobhan Crilly

h-index: 9
Works: 25
Citations: 235

Most-cited papers

Impaired eIF5A function causes a Mendelian disorder that is partially rescued in model systems by spermidine
V. Faundes, Martin D. Jennings, Siobhan Crilly, Sarah Legraie +20 more
2021Nature Communications56 citations Open access
Semantic Scholar
Using zebrafish larval models to study brain injury, locomotor and neuroinflammatory outcomes following intracerebral haemorrhage
Siobhan Crilly, Alexandra Njegic, S. Laurie, E. Fotiou +10 more
2018F1000Research31 citations Open access
Semantic Scholar
Analysis of U8 snoRNA Variants in Zebrafish Reveals How Bi-allelic Variants Cause Leukoencephalopathy with Calcifications and Cysts.
Andrew P. Badrock, Carolina Uggenti, L. Wacheul, Siobhan Crilly +6 more
2020American Journal of Human Genetics28 citations Open access
Semantic Scholar
Cerebral Organoids with Integrated Endothelial Networks Emulate the Neurovascular Unit and Mitigate Core Necrosis
Josep Fumadó Navarro, Siobhan Crilly, Wai-Kit Chan, S. Browne +4 more
2025bioRxiv22 citations Open access
Semantic Scholar
Using Zebrafish Larvae to Study the Pathological Consequences of Hemorrhagic Stroke.
Siobhan Crilly, Alexandra Njegic, A. Parry-Jones, S. Allan +1 more
2019Journal of Visualized Experiments18 citations Open access
Semantic Scholar
Zebrafish drug screening identifies candidate therapies for neuroprotection after spontaneous intracerebral haemorrhage
Siobhan Crilly, A. Parry-Jones, Xia Wang, Julian N. Selley +5 more
2022Disease Models & Mechanisms15 citations Open access
Semantic Scholar
Zebrafish for modeling stroke and their applicability for drug discovery and development
Siobhan Crilly, Emily McMahon, Paul R. Kasher
2022Expert Opinion on Drug Discovery14 citations Open access
Semantic Scholar
Revisiting promising preclinical intracerebral hemorrhage studies to highlight repurposable drugs for translation
Siobhan Crilly, Sarah E. Withers, S. Allan, A. Parry-Jones +1 more
2020International Journal of Stroke13 citations Open access
Semantic Scholar
The role of 25-hydroxycholesterol in the pathophysiology of brain vessel dysfunction associated with infection and cholesterol dysregulation
Victor S. Tapia, Sarah E. Withers, Ran Zhou, Abigail Bennington +9 more
2025Disease Models & Mechanisms10 citations Open access
Semantic Scholar
Characterization of a mutant samhd1 zebrafish model implicates dysregulation of cholesterol biosynthesis in Aicardi-Goutières syndrome
Sarah E. Withers, Charlie F. Rowlands, Victor S. Tapia, Frances Hedley +8 more
2023Frontiers in Immunology8 citations Open access
Semantic Scholar
Human in vitro models of neurovasculature and the application to pre-clinical intracerebral haemorrhage research
Siobhan Crilly, Mihai Lomora
2025Bioactive Materials5 citations Open access
Semantic Scholar
Investigating recovery after a spontaneous intracerebral haemorrhage in zebrafish larvae
Siobhan Crilly, I. Shand, Abigail Bennington, Emily McMahon +3 more
2024Brain Communications4 citations Open access
Semantic Scholar
Using zebrafish larval models to study brain injury, locomotor and neuroinflammatory outcomes following intracerebral haemorrhage [version 1; peer review: 1 approved, 1 approved with reservations]
Siobhan Crilly, Alexandra Njegic, S. Laurie, E. Fotiou +10 more
20213 citations
Semantic Scholar
Loss of col4a1 in zebrafish recapitulates the cerebrovascular phenotypes associated with monogenic cerebral small vessel disease.
Daisy Flatman, Richard Naylor, Siobhan Crilly, I. Carter +5 more
2025Matrix Biology2 citations Open access
Semantic Scholar
Developing an in vitro model of haematoma for study of intracerebral haemorrhage.
Siobhan Crilly, Victor S. Tapia, C. Bawn, A. Tirella
2024Biomaterials Science2 citations Open access
Semantic Scholar
RNA-Seq Dataset From Isolated Leukocytes Following Spontaneous Intracerebral Hemorrhage in Zebrafish Larvae
Siobhan Crilly, J. Cooper, L. Bradford, Ian E. Prise +2 more
2021Frontiers in Cellular Neuroscience2 citations Open access
Semantic Scholar
Editorial: Innovative models of stroke pathology
Siobhan Crilly, M. Zille, Paul R. Kasher, M. Modo
2023Frontiers in Neurology1 citations Open access
Semantic Scholar
Novel intramolecular base-pairing of the U8 snoRNA underlies a Mendelian form of cerebral small vessel disease
Andrew P. Badrock, Carolina Uggenti, L. Wacheul, Siobhan Crilly +6 more
2019bioRxiv1 citations Open access
Semantic Scholar
Hematoma Interleukin‐1 Receptor Antagonist Concentrations Predict Long‐Term Outcome in Acute Human Intracerebral Hemorrhage
A. Parry-Jones, Blessing Nyakutsikwa, M. Askenase, M. Gittins +9 more
2026Annals of Neurology0 citations Open access
Semantic Scholar
Using atorvastatin-induced vascular weakness to model brain haemorrhage in vascularised cerebral organoids
Siobhan Crilly, S. Sundararaman, Michael J. Haley, Elisa Segantin +7 more
2026bioRxiv0 citations Open access
Semantic Scholar
25-hydroxycholesterol promotes brain endothelial dysfunction by remodelling cholesterol metabolism
Victor S. Tapia, Sarah E. Withers, Ran Zhou, Abigail Bennington +8 more
2024bioRxiv0 citations Open access
Semantic Scholar
Identifying applications of virtual reality to benefit the stroke translational pipeline
Matan Bone, Maham Malik, Siobhan Crilly
2023Brain and Neuroscience Advances0 citations Open access
Semantic Scholar
First person – Siobhan Crilly
Paul R. Kasher, A. Tirella, Siobhan Crilly
2022Disease Models & Mechanisms0 citations Open access
Semantic Scholar
A method for transplantation of human HSCs into zebrafish(cid:401) to replace humanised murine transplantation models (cid:446)version
Siobhan Crilly
20190 citations
Semantic Scholar
A method for transplantation of human HSCs into zebrafishゴ to replace humanised murine transplantation models ┕ version ÷ザ refereesジ
Siobhan Crilly
20180 citations
Semantic Scholar

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