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S. Glerup · SciRah

Researcher profile · Semantic Scholar

S. Glerup

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S. Glerup — researcher profile on SciRah

h-index: 25
Works: 72
Citations: 2,245

Most-cited papers

Sortilin associates with Trk receptors to enhance anterograde transport and signaling by neurotrophins
C. Vaegter, Pernille Jansen, A. N. Fjorback, S. Glerup +10 more
2010Nature Neuroscience189 citations Open access
Semantic Scholar
The hypercholesterolemia-risk gene SORT1 facilitates PCSK9 secretion.
Camilla Gustafsen, M. Kjolby, M. Nyegaard, M. Mattheisen +7 more
2014Cell Metabolism170 citations Open access
Semantic Scholar
Targeting PCSK9 to tackle cardiovascular disease.
Sandra Hummelgaard, J. Vilstrup, Camilla Gustafsen, S. Glerup +1 more
2023Pharmacology and Therapeutics135 citations Open access
Semantic Scholar
APOE4-mediated amyloid-&bgr; pathology depends on its neuronal receptor LRP1
Masaya Tachibana, Marie-Louise Holm, Chia-Chen Liu, M. Shinohara +11 more
2019Journal of Clinical Investigation133 citations Open access
Semantic Scholar
Sortilin and SorLA Display Distinct Roles in Processing and Trafficking of Amyloid Precursor Protein
Camilla Gustafsen, S. Glerup, L. T. Pallesen, Ditte Olsen +4 more
2013Journal of Neuroscience110 citations Open access
Semantic Scholar
Heparan sulfate proteoglycans present PCSK9 to the LDL receptor
Camilla Gustafsen, Ditte Olsen, J. Vilstrup, Signe Lund +10 more
2017Nature Communications109 citations Open access
Semantic Scholar
SorCS2 is required for BDNF-dependent plasticity in the hippocampus
S. Glerup, U. Bolcho, S. Mølgaard, S. Bøggild +14 more
2016Molecular Psychiatry91 citations
Semantic Scholar
SorCS2 regulates dopaminergic wiring and is processed into an apoptotic two-chain receptor in peripheral glia.
S. Glerup, Ditte Olsen, C. Vaegter, Camilla Gustafsen +19 more
2014Neuron91 citations Open access
Semantic Scholar
Sortilin-Related Receptor SORCS3 Is a Postsynaptic Modulator of Synaptic Depression and Fear Extinction
T. Breiderhoff, G. Christiansen, L. T. Pallesen, C. Vaegter +4 more
2013PLoS ONE89 citations Open access
Semantic Scholar
Physiological and therapeutic regulation of PCSK9 activity in cardiovascular disease
S. Glerup, R. Schulz, U. Laufs, K. Schlüter
2017Basic Research in Cardiology85 citations Open access
Semantic Scholar
Glutamate-system defects behind psychiatric manifestations in a familial hemiplegic migraine type 2 disease-mutation mouse model
Pernille Bøttger, S. Glerup, Bodil Gesslein, N. Illarionova +11 more
2016Scientific Reports85 citations Open access
Semantic Scholar
SorLA regulates the activity of lipoprotein lipase by intracellular trafficking
Stine C. Klinger, S. Glerup, M. K. Raarup, M. Mari +10 more
201171 citations
Semantic Scholar
Mapping of the Interaction Site between Sortilin and the p75 Neurotrophin Receptor Reveals a Regulatory Role for the Sortilin Intracellular Domain in p75 Neurotrophin Receptor Shedding and Apoptosis*
S. Skeldal, A. Sykes, S. Glerup, Dusan Matusica +7 more
2012Journal of Biological Chemistry66 citations Open access
Semantic Scholar
SorLA controls neurotrophic activity by sorting of GDNF and its receptors GFRα1 and RET.
S. Glerup, Maria Lume, Ditte Olsen, J. Nyengaard +10 more
2013Cell Reports65 citations Open access
Semantic Scholar
Temporal course of pregnancy-associated plasma protein-A in angioplasty-treated ST-elevation myocardial infarction patients and potential significance of concomitant heparin administration.
C. Terkelsen, C. Oxvig, B. Nørgaard, S. Glerup +7 more
2009American Journal of Cardiology51 citations
Semantic Scholar
Proteinase Inhibition by Proform of Eosinophil Major Basic Protein (pro-MBP) Is a Multistep Process of Intra- and Intermolecular Disulfide Rearrangements*
S. Glerup, H. Boldt, M. Overgaard, L. Sottrup-jensen +2 more
2005Journal of Biological Chemistry48 citations Open access
Semantic Scholar
Increased serum levels of sortilin are associated with depression and correlated with BDNF and VEGF
H. Buttenschon, D. Demontis, M. Kaas, B. Elfving +7 more
2015Translational Psychiatry43 citations Open access
Semantic Scholar
Sortilins in neurotrophic factor signaling.
S. Glerup, Anders Nykjaer, C. Vaegter
2014Handbook of Experimental Pharmacology40 citations
Semantic Scholar
Cognitive deficits caused by a disease-mutation in the α3 Na+/K+-ATPase isoform
T. H. Holm, T. Isaksen, S. Glerup, A. Heuck +7 more
2016Scientific Reports38 citations Open access
Semantic Scholar
Inhibition of proteolysis by the proform of eosinophil major basic protein (proMBP) requires covalent binding to its target proteinase
M. Overgaard, S. Glerup, H. Boldt, Vivien Rodacker +5 more
2004FEBS Letters33 citations
Semantic Scholar
Loss of BDNF or its receptors in three mouse models has unpredictable consequences for anxiety and fear acquisition.
Ditte Olsen, M. Kaas, O. Schwartz, A. Nykjaer +1 more
2013Learning & memory (Cold Spring Harbor, N.Y.)30 citations Open access
Semantic Scholar
Placental Regulation of Peptide Hormone and Growth Factor Activity by proMBP1
K. Weyer, S. Glerup
2011Biology of Reproduction30 citations Open access
Semantic Scholar
Whole-Exome Sequencing Reveals Increased Burden of Rare Functional and Disruptive Variants in Candidate Risk Genes in Individuals With Persistent Attention-Deficit/Hyperactivity Disorder.
D. Demontis, F. Lescai, A. Børglum, S. Glerup +11 more
2016Journal of the American Academy of Child and Adolescent Psychiatry29 citations Open access
Semantic Scholar
Spatiotemporal patterns of sortilin and SorCS2 localization during organ development
S. Boggild, Simon Mølgaard, S. Glerup, J. Nyengaard
2016BMC Cell Biology28 citations Open access
Semantic Scholar
Proprotein convertase subtilisin/kexin type 9 targets megalin in the kidney proximal tubule and aggravates proteinuria in nephrotic syndrome.
Cecilie K. Skeby, Sandra Hummelgaard, Camilla Gustafsen, Federica Petrillo +10 more
2023Kidney International26 citations Open access
Semantic Scholar
Identification of a Linear Epitope in Sortilin That Partakes in Pro-neurotrophin Binding*
Olga Serup Andersen, P. Boisguérin, S. Glerup, S. Skeldal +4 more
2010Journal of Biological Chemistry22 citations Open access
Semantic Scholar
Brain volumetric alterations accompanied with loss of striatal medium-sized spiny neurons and cortical parvalbumin expressing interneurons in Brd1+/− mice
P. Qvist, S. Eskildsen, B. Hansen, Mohammad Baragji +12 more
2018Scientific Reports21 citations Open access
Semantic Scholar
Cell Surface Detachment of Pregnancy-associated Plasma Protein-A Requires the Formation of Intermolecular Proteinase-Inhibitor Disulfide Bonds and Glycosaminoglycan Covalently Bound to the Inhibitor*
S. Glerup, Søren Kløverpris, L. S. Laursen, F. Dagnæs-Hansen +3 more
2007Journal of Biological Chemistry21 citations Open access
Semantic Scholar
Definition, expression, and characterization of a protein domain in the N-terminus of pregnancy-associated plasma protein-A distantly related to the family of laminin G-like modules.
H. Boldt, S. Glerup, M. Overgaard, L. Sottrup-jensen +1 more
2006Protein Expression and Purification21 citations
Semantic Scholar
Risk locus identification ties alcohol withdrawal symptoms to SORCS2
Andrew H. Smith, P. Ovesen, S. Skeldal, Seungeun Yeo +10 more
2018Alcoholism: Clinical and Experimental Research18 citations Open access
Semantic Scholar
Formation of high-molecular-weight angiotensinogen during pregnancy is a result of competing redox reactions with the proform of eosinophil major basic protein.
Søren Kløverpris, L. Skov, S. Glerup, K. Pihl +2 more
2013Biochemical Journal18 citations
Semantic Scholar
Altered dopaminergic firing pattern and novelty response underlie ADHD-like behavior of SorCS2-deficient mice
Ditte Olsen, Niels Wellner, M. Kaas, I. D. de Jong +4 more
2021Translational Psychiatry16 citations Open access
Semantic Scholar
Soluble sortilin is present in excess and positively correlates with progranulin in CSF of aging individuals.
Simon Mølgaard, D. Demontis, Alexandra M. Nicholson, N. Finch +5 more
2016Experimental Gerontology15 citations
Semantic Scholar
Immunofluorescent visualization of mouse interneuron subtypes
Simon Mølgaard, Maj Ulrichsen, S. Boggild, Marie-Louise Holm +3 more
2014F1000Research15 citations Open access
Semantic Scholar
PCSK9 deficiency alters brain lipid composition without affecting brain development and function
Angela Pärn, Ditte Olsen, Jürgen Tuvikene, M. Kaas +11 more
2023Frontiers in Molecular Neuroscience14 citations Open access
Semantic Scholar
Df(h22q11)/+ mouse model exhibits reduced binding levels of GABAA receptors and structural and functional dysregulation in the inhibitory and excitatory networks of hippocampus.
Abdel-Rahman Al-Absi, Sakeerthi Kethees Thambiappa, A. R. Khan, S. Glerup +3 more
2022Molecular and cellular neurosciences13 citations Open access
Semantic Scholar
Layers II/III of Prefrontal Cortex in Df(h22q11)/+ Mouse Model of the 22q11.2 Deletion Display Loss of Parvalbumin Interneurons and Modulation of Neuronal Morphology and Excitability
Abdel-Rahman Al-Absi, P. Qvist, S. Okujeni, A. R. Khan +3 more
2020Molecular Neurobiology13 citations
Semantic Scholar
Association between circulating proprotein convertase subtilisin/kexin type 9 levels and prognosis in patients with severe chronic kidney disease.
L. D. Rasmussen, M. Bøttcher, P. Ivarsen, H. Jørgensen +7 more
2018Nephrology, Dialysis and Transplantation13 citations
Semantic Scholar
Detection of phosphorylated Akt and MAPK in cell culture assays
Simon Mølgaard, Maj Ulrichsen, Ditte Olsen, S. Glerup
2016MethodsX13 citations Open access
Semantic Scholar
Morphological profiling in human neural progenitor cells classifies hits in a pilot drug screen for Alzheimer’s disease
Amina McDiarmid, K. Gospodinova, Richard J. R. Elliott, John C. Dawson +7 more
2024Brain Communications12 citations Open access
Semantic Scholar
Sortilin Modulates Schwann Cell Signaling and Remak Bundle Regeneration Following Nerve Injury
Maj Ulrichsen, N. Gonçalves, S. Mohseni, Simone Hjæresen +8 more
2022Frontiers in Cellular Neuroscience12 citations Open access
Semantic Scholar
APOE 4-mediated amyloid-b pathology depends on its neuronal receptor LRP 1
Masaya Tachibana, Marie-Louise Holm, Chia-Chen Liu, M. Shinohara +11 more
201912 citations
Semantic Scholar
Highly segregated localization of the functionally related vps10p receptors sortilin and SorCS2 during neurodevelopment
S. Boggild, Simon Mølgaard, S. Glerup, J. Nyengaard
2018The Journal of comparative neurology12 citations
Semantic Scholar
SorLA regulates the activity of lipoprotein lipase by intracellular trafficking
Stine C. Klinger, S. Glerup, M. K. Raarup, M. Mari +10 more
2011Journal of Cell Science12 citations
Semantic Scholar
The Proform of the Eosinophil Major Basic Protein Binds the Cell Surface through a Site Distinct from Its C-type Lectin Ligand-binding Region*
S. Glerup, Søren Kløverpris, C. Oxvig
2006Journal of Biological Chemistry10 citations Open access
Semantic Scholar
Investigation of serum levels of sortilin in response to antidepressant treatment
H. Buttenschøn, M. Nielsen, S. Glerup, O. Mors
2017Acta Neuropsychiatrica9 citations
Semantic Scholar
Reduced Alcohol Seeking and Withdrawal Symptoms in Mice Lacking the BDNF Receptor SorCS2
Ditte Olsen, M. Kaas, Jesper Lundhede, Simon Mølgaard +4 more
2019Frontiers in Pharmacology8 citations Open access
Semantic Scholar
Df(h15q13)/+ Mouse Model Reveals Loss of Astrocytes and Synaptic-Related Changes of the Excitatory and Inhibitory Circuits in the Medial Prefrontal Cortex.
Abdel-Rahman Al-Absi, P. Qvist, S. Glerup, C. Sánchez +1 more
2020Cerebral Cortex7 citations Open access
Semantic Scholar
Loss of SORCS2 is Associated with Neuronal DNA Double-Strand Breaks
K. Gospodinova, Ditte Olsen, M. Kaas, S. Anderson +11 more
2021bioRxiv6 citations Open access
Semantic Scholar
Alternative splicing regulates adaptor protein binding, trafficking, and activity of the Vps10p domain receptor SorCS2 in neuronal development
S. Skeldal, L. Voss, J. Lende, Sarah Bro Pedersen +10 more
2023Journal of Biological Chemistry5 citations Open access
Semantic Scholar

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