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M. Londei · SciRah

Researcher profile · Semantic Scholar

M. Londei

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M. Londei — researcher profile on SciRah

h-index: 44
Works: 157
Citations: 9,131

Most-cited papers

Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn’s disease: unexpected results of a randomised, double-blind placebo-controlled trial
W. Hueber, B. Sands, S. Lewitzky, Marc Vandemeulebroecke +16 more
2012Gut1,503 citations Open access
Semantic Scholar
Prevention of Arthritis by Interleukin 10–producing B Cells
C. Mauri, D. Gray, Naseem Mushtaq, M. Londei
2003Journal of Experimental Medicine922 citations Open access
Semantic Scholar
Association between innate response to gliadin and activation of pathogenic T cells in coeliac disease.
L. Maiuri, C. Ciacci, I. Ricciardelli, L. Vacca +6 more
2003The Lancet647 citations
Semantic Scholar
Interleukin 15 mediates epithelial changes in celiac disease.
L. Maiuri, C. Ciacci, S. Auricchio, V. Brown +2 more
2000Gastroenterology264 citations Open access
Semantic Scholar
CD45 isoforms expression on CD4+ and CD8+ T cells throughout life, from newborns to centenarians: implications for T cell memory.
A. Cossarizza, C. Ortolani, R. Paganelli, D. Barbieri +7 more
1996Mechanisms of Ageing and Development246 citations Open access
Semantic Scholar
Proof-of-concept clinical trial of etokimab shows a key role for IL-33 in atopic dermatitis pathogenesis
Yi-Ling Chen, D. Gutowska-Owsiak, Clare S. Hardman, M. Westmoreland +7 more
2019Science Translational Medicine219 citations Open access
Semantic Scholar
Celiac disease: in vitro and in vivo safety and palatability of wheat-free sorghum food products.
C. Ciacci, L. Maiuri, N. Caporaso, C. Bucci +7 more
2007Clinical Nutrition184 citations
Semantic Scholar
Phase 2a randomized, placebo-controlled study of anti-IL-33 in peanut allergy.
S. Chinthrajah, S. Cao, Cherie Liu, Shu-Chen Lyu +6 more
2019JCI Insight172 citations Open access
Semantic Scholar
Definition of the initial immunologic modifications upon in vitro gliadin challenge in the small intestine of celiac patients.
L. Maiuri, A. Picarelli, M. Boirivant, S. Coletta +4 more
1996Gastroenterology165 citations
Semantic Scholar
Production of antiendomysial antibodies after in-vitro gliadin challenge of small intestine biopsy samples from patients with coeliac disease.
A. Picarelli, L. Maiuri, A. Frate, M. Greco +2 more
1996The Lancet159 citations
Semantic Scholar
Lysosomal accumulation of gliadin p31–43 peptide induces oxidative stress and tissue transglutaminase-mediated PPARγ downregulation in intestinal epithelial cells and coeliac mucosa
A. Luciani, V. R. Villella, A. Vasaturo, I. Giardino +7 more
2009Gut150 citations
Semantic Scholar
Split activity of interleukin‐10 on antigen capture and antigen presentation by human dendritic cells: Definition of a maturative step
Anne‐Sophie Morel, S. Quaratino, D. Douek, M. Londei
1997European Journal of Immunology144 citations
Semantic Scholar
Unexpected role of surface transglutaminase type II in celiac disease.
L. Maiuri, C. Ciacci, I. Ricciardelli, L. Vacca +6 more
2005Gastroenterology139 citations Open access
Semantic Scholar
Therapeutic activity of agonistic monoclonal antibodies against CD40 in a chronic autoimmune inflammatory process
C. Mauri, L. Mars, M. Londei
2000Nature Medicine139 citations
Semantic Scholar
Tissue Transglutaminase Activation Modulates Inflammation in Cystic Fibrosis via PPARγ Down-Regulation1
L. Maiuri, A. Luciani, I. Giardino, V. Raia +9 more
2008Journal of Immunology129 citations Open access
Semantic Scholar
Evidence of Chronic Inflammation in Morphologically Normal Small Intestine of Cystic Fibrosis Patients
V. Raia, L. Maiuri, Giorgio de Ritis, B. de Vizia +4 more
2000Pediatric Research116 citations
Semantic Scholar
Anti tumour necrosis‐α therapy increases the number of FOXP3+ regulatory T cells in children affected by Crohn’s disease
I. Ricciardelli, K. Lindley, M. Londei, S. Quaratino
2008Immunology112 citations Open access
Semantic Scholar
Similar antigenic surfaces, rather than sequence homology, dictate T-cell epitope molecular mimicry.
S. Quaratino, Christopher J. Thorpe, P. Travers, M. Londei
1995Proceedings of the National Academy of Sciences of the United States of America108 citations Open access
Semantic Scholar
Immune reactivity to glutamic acid decarboxylase 65 in stiffman syndrome and type 1 diabetes mellitus.
Tobias Lohmann, M. Hawa, R. Leslie, Russell J. M. Lane +2 more
2000The Lancet101 citations
Semantic Scholar
Lipopolysaccharide Stimulates the Proliferation of Human CD56+CD3− NK Cells: A Regulatory Role of Monocytes and IL-101
M. Goodier, M. Londei
2000Journal of Immunology93 citations
Semantic Scholar
Gliadin as a stimulator of innate responses in celiac disease.
M. Londei, C. Ciacci, I. Ricciardelli, L. Vacca +2 more
2005Molecular Immunology81 citations
Semantic Scholar
Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases define the migratory characteristics of human monocyte‐derived dendritic cells
Mohamed Osman, M. Tortorella, M. Londei, S. Quaratino
2002Immunology81 citations Open access
Semantic Scholar
Degenerate self-reactive human T-cell receptor causes spontaneous autoimmune disease in mice
S. Quaratino, E. Badami, Y. Pang, I. Bartok +4 more
2004Nature Medicine66 citations
Semantic Scholar
IL-15 drives the specific migration of CD94+ and TCR-γδ+ intraepithelial lymphocytes in organ cultures of treated celiac patients
L. Maiuri, C. Ciacci, L. Vacca, I. Ricciardelli +3 more
2001American Journal of Gastroenterology64 citations
Semantic Scholar
Human self-reactive T cell clones expressing identical T cell receptor beta chains differ in their ability to recognize a cryptic self-epitope
S. Quaratino, M. Feldmann, C. Dayan, O. Acuto +1 more
1996Journal of Experimental Medicine63 citations Open access
Semantic Scholar
Human macrophages induced in vitroby macrophage colony‐stimulating factor are deficient in IL‐12 production
William Smith, M. Feldmann, M. Londei
1998European Journal of Immunology61 citations Open access
Semantic Scholar
CD47 Ligation Induces a Rapid Caspase‐Independent Apoptosis‐Like Cell Death in Human Monocytes and Dendritic Cells
U. Johansson, K. Higginbottom, M. Londei
2004Scandinavian Journal of Immunology57 citations
Semantic Scholar
Gliadin Regulates the NK-Dendritic Cell Cross-Talk by HLA-E Surface Stabilization1
G. Terrazzano, M. Sica, C. Gianfrani, G. Mazzarella +11 more
2007Journal of Immunology56 citations Open access
Semantic Scholar
Inhibition of p38 mitogen activated protein kinase controls airway inflammation in cystic fibrosis
V. Raia, L. Maiuri, C. Ciacci, I. Ricciardelli +9 more
2005Thorax51 citations Open access
Semantic Scholar
DNA fragmentation is a feature of cystic fibrosis epithelial cells: a disease with inappropriate apoptosis?
L. Maiuri, V. Raia, G. de Marco, S. Coletta +3 more
1997FEBS Letters50 citations
Semantic Scholar
Blockage of T-cell costimulation inhibits T-cell action in celiac disease.
L. Maiuri, S. Auricchio, S. Coletta, G. de Marco +4 more
1998Gastroenterology49 citations
Semantic Scholar
Glutamic acid decarboxylase T lymphocyte responses associated with susceptibility or resistance to type I diabetes: analysis in disease discordant human twins, non-obese diabetic mice and HLA-DQ transgenic mice.
R. Boyton, T. Lohmann, M. Londei, H. Kalbacher +6 more
1998International Immunology49 citations Open access
Semantic Scholar
Protein Conformation Significantly Influences Immune Responses to Prion Protein1
A. Khalili-Shirazi, S. Quaratino, M. Londei, Linda Summers +5 more
2005Journal of Immunology48 citations Open access
Semantic Scholar
Differential effects of interleukin‐10 on the expression of HLA class II and CD1 molecules induced by granulocyte/macrophage colony‐stimulating factor/interleukin‐4
H. Thomssen, M. Kahan, M. Londei
1995European Journal of Immunology43 citations
Semantic Scholar
Optimal human pathogenic TH2 cell effector function requires local epithelial cytokine signaling
J. Calise, Nahir Garabatos, V. Bajzik, M. Farrington +4 more
2021Journal of Allergy and Clinical Immunology42 citations Open access
Semantic Scholar
IL-15 drives the specific migration of CD94+ and TCR-gammadelta+ intraepithelial lymphocytes in organ cultures of treated celiac patients.
L. Maiuri, C. Ciacci, L. Vacca, I. Ricciardelli +3 more
2001American Journal of Gastroenterology36 citations
Semantic Scholar
Autoantibody-mediated capture and presentation of autoantigen to T cells via the Fc epsilon receptor by a recombinant human autoantibody Fab converted to IgE.
Jin Guo, S. Quaratino, J. Jaume, G. Costante +3 more
1996JIM - Journal of Immunological Methods35 citations
Semantic Scholar
Humoral and Cellular Autoimmune Responses in Stiff Person Syndrome
T. Lohmann, M. Londei, M. Hawa, R. D. Leslie
2003Annals of the New York Academy of Sciences34 citations
Semantic Scholar
Expression of IL-33 and TSLP and Their Receptors in Asthmatic Airways after Inhaled Allergen Challenge.
D. Al‐Sajee, R. Sehmi, T. Hawke, Amani I. El-Gammal +5 more
2018American Journal of Respiratory and Critical Care Medicine33 citations
Semantic Scholar
Ligation of CD47 During Monocyte Differentiation into Dendritic Cells Results in Reduced Capacity for Interleukin‐12 Production
U. Johansson, M. Londei
2004Scandinavian Journal of Immunology28 citations
Semantic Scholar
Altered Monocyte Cyclooxygenase Response to Lipopolysaccharide in Type 1 Diabetes
H. Beyan, M. Goodier, N. Nawroly, M. Hawa +5 more
2006Diabetes27 citations Open access
Semantic Scholar
Reactive Nitrogen Species Modulate the Effects of Rhein, an Active Component of Senna Laxatives, on Human Epithelium In Vitro
F. Raimondi, P. Santoro, L. Maiuri, M. Londei +3 more
2002Journal of Pediatric Gastroenterology and Nutrition - JPGN27 citations Open access
Semantic Scholar
Human CD4-CD8- alpha beta + T-cell receptor T cells recognize different mycobacteria strains in the context of CD1b.
H. Thomssen, J. Ivanyi, C. Espitia, A. Arya +1 more
1995Immunology27 citations
Semantic Scholar
Management of Fulminating Ulcerative Colitis in Childhood with Chimeric Anti-CD25 Antibody
A. Schwarzer, I. Ricciardelli, S. Kirkham, K. Binnie +9 more
2006Journal of Pediatric Gastroenterology and Nutrition - JPGN26 citations Open access
Semantic Scholar
Human Autoantibodies Modulate the T Cell Epitope Repertoire but Fail to Unmask a Pathogenic Cryptic Epitope1
S. Quaratino, J. Ruf, Mohamed Osman, Jin Guo +3 more
2005Journal of Immunology26 citations Open access
Semantic Scholar
Inhibition of IL-12 production in human dendritic cells matured in the presence of Bacillus Calmette-Guerin or lipoarabinomannan.
U. Johansson, J. Ivanyi, M. Londei
2001Immunology Letters25 citations
Semantic Scholar
A Phase 1 Study of ANB020, an anti-IL-33 monoclonal Antibody in Healthy Volunteers
M. Londei, B. Kenney, G. Los, M. H. Marino
201724 citations
Semantic Scholar
T cell repertoire usage in humans, from newborns to centenarians.
A. Cossarizza, D. Barbieri, M. Londei
1995International Reviews of Immunology22 citations Open access
Semantic Scholar
Role of regulatory T cells in experimental arthritis and implications for clinical use
M. Londei
2005Arthritis Research & Therapy20 citations Open access
Semantic Scholar
IL-2 Immunotherapy Reveals Potential for Innate Beta Cell Regeneration in the Non-Obese Diabetic Mouse Model of Autoimmune Diabetes
Yaiza Diaz-de-Durana, J. Lau, D. Knee, Christophe M. Filippi +6 more
2013PLoS ONE16 citations Open access
Semantic Scholar

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